Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Incorporate RNAplex model with seed heuristic #37

Open
martin-raden opened this issue Nov 25, 2016 · 2 comments
Open

Incorporate RNAplex model with seed heuristic #37

martin-raden opened this issue Nov 25, 2016 · 2 comments

Comments

@martin-raden
Copy link
Member

  • include RNAplex model
  • enable seed heuristic
  • enable nested + pseudoknot accessibilities
@martin-raden
Copy link
Member Author

accessibility computation models to be tested

  • RNAplex
  • Accessfold
  • NUPACK-based

@martin-raden
Copy link
Member Author

concerning NUPACK

NUPACK enables the computation of (position-wise) unpaired probabilities. These could be incorporated in a AccessFold-like approach to incorporate pseudoknotted intramolecular structure into the interaction prediction.

Two options:

  • read Pu values from NUPACK ppairs output file
  • use NUPACK library for direct computation (check if possible)

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Projects
None yet
Development

No branches or pull requests

1 participant