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10.1007%2Fs00424-004-1377-z.pcr
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10.1007%2Fs00424-004-1377-z.pcr
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[
{
"annotId": "ae9d0c74-0af5-11e6-9abd-64006a4c56ef",
"authors": [
"oreilly"
],
"comment": "Age of rats used for the evaluation of calcium-binding protein expression.",
"experimentProperties": [],
"localizer": {
"location": 20395,
"text": "14-\nto 21-day-old rats",
"type": "text"
},
"parameters": [
{
"description": {
"depVar": {
"typeId": "BBP-002001",
"values": {
"type": "compound",
"valueLst": [
{
"statistic": "min",
"type": "simple",
"unit": "d",
"values": [
14
]
},
{
"statistic": "max",
"type": "simple",
"unit": "d",
"values": [
21
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}
]
}
},
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},
"id": "d9bd213c-0af5-11e6-9abd-64006a4c56ef",
"isExperimentProperty": true,
"requiredTags": []
}
],
"pubId": "10.1007/s00424-004-1377-z",
"tags": [
{
"id": "NIFGA:birnlex_1595",
"name": "Dorsal nucleus of lateral geniculate body"
},
{
"id": "NIFORG:nlx_organ_20081201",
"name": "Long Evans Rat"
}
],
"version": "1"
},
{
"annotId": "dbcb27d0-0af5-11e6-9abd-64006a4c56ef",
"authors": [
"oreilly"
],
"comment": "From 60um thick slices; Nissl staining; Annotation with general category \"Neuron\" since Nissl staining shows both TC cells and interneurons (which proportion is not negligeable in rats in LGN); from 6 slices from 3 animals.",
"experimentProperties": [
{
"instanceId": "d9bd213c-0af5-11e6-9abd-64006a4c56ef",
"paramTypeId": "BBP-002001"
}
],
"localizer": {
"location": 20472,
"text": "overall density of neurons in the dLGN\nof 5,434\u00b1326 cells/mm2",
"type": "text"
},
"parameters": [
{
"description": {
"depVar": {
"typeId": "BBP-131001",
"values": {
"type": "compound",
"valueLst": [
{
"statistic": "mean",
"type": "simple",
"unit": "1/mm^2",
"values": [
5434
]
},
{
"statistic": "sem",
"type": "simple",
"unit": "1/mm^2",
"values": [
326
]
},
{
"statistic": "N",
"type": "simple",
"unit": "dimensionless",
"values": [
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}
]
}
},
"type": "pointValue"
},
"id": "01fbb77a-0af7-11e6-9abd-64006a4c56ef",
"isExperimentProperty": false,
"requiredTags": [
{
"id": "NIFGA:birnlex_1662",
"name": "Lateral geniculate body",
"rootId": "NIFGA:birnlex_1167"
},
{
"id": "NIFCELL:sao1417703748",
"name": "Neuron",
"rootId": "NIFCELL:sao1813327414"
}
]
}
],
"pubId": "10.1007/s00424-004-1377-z",
"tags": [
{
"id": "NIFGA:birnlex_1595",
"name": "Dorsal nucleus of lateral geniculate body"
},
{
"id": "NIFORG:nlx_organ_20081201",
"name": "Long Evans Rat"
}
],
"version": "1"
},
{
"annotId": "009c137c-0afa-11e6-89e6-64006a4c56ef",
"authors": [
"oreilly"
],
"comment": "CB : Calbindin-D28K",
"experimentProperties": [
{
"instanceId": "d9bd213c-0af5-11e6-9abd-64006a4c56ef",
"paramTypeId": "BBP-002001"
}
],
"localizer": {
"location": 20721,
"text": "In dLGN\nslices, CB-immunoreactive cells were found at a density\nof 183\u00b141 cells/mm2 (n=3), indicating that about 3%\nof neurons in dLGN express CB. Among the CB-positive\nstructures small (soma diameter 8\u201312 lm) bipolar\ncells (Fig. 3A) and, to a much lesser extent, large (soma\ndiameter 15\u201325 lm) multipolar cells could be identified,\nmost likely representing interneurons and relay neurons,\nrespectively [21, 24, 48].",
"type": "text"
},
"parameters": [],
"pubId": "10.1007/s00424-004-1377-z",
"tags": [
{
"id": "NIFGA:birnlex_1595",
"name": "Dorsal nucleus of lateral geniculate body"
},
{
"id": "NIFORG:nlx_organ_20081201",
"name": "Long Evans Rat"
},
{
"id": "NIFGA:birnlex_1595",
"name": "Dorsal nucleus of lateral geniculate body"
},
{
"id": "NIFORG:nlx_organ_20081201",
"name": "Long Evans Rat"
}
],
"version": "1"
},
{
"annotId": "28a9cc60-0afa-11e6-89e6-64006a4c56ef",
"authors": [
"oreilly"
],
"comment": "CR-labelled neurons were found at a density of 488\u00b132 cells/mm2 (n=3 slices), indicating that about 9% of dLGN neurons express CR. Size and shape of CR-positive cells were indicative of interneurons (Fig. 3A).\n\nCR: calretinin",
"experimentProperties": [
{
"instanceId": "d9bd213c-0af5-11e6-9abd-64006a4c56ef",
"paramTypeId": "BBP-002001"
}
],
"localizer": {
"location": 21275,
"text": "CR-labelled\nneurons were found at a density of 488\u00b132 cells/mm2",
"type": "text"
},
"parameters": [],
"pubId": "10.1007/s00424-004-1377-z",
"tags": [
{
"id": "NIFGA:birnlex_1595",
"name": "Dorsal nucleus of lateral geniculate body"
},
{
"id": "NIFORG:nlx_organ_20081201",
"name": "Long Evans Rat"
},
{
"id": "NIFGA:birnlex_1595",
"name": "Dorsal nucleus of lateral geniculate body"
},
{
"id": "NIFORG:nlx_organ_20081201",
"name": "Long Evans Rat"
}
],
"version": "1"
},
{
"annotId": "6001200a-0afa-11e6-89e6-64006a4c56ef",
"authors": [
"oreilly"
],
"comment": "PV: parvalbumin",
"experimentProperties": [
{
"instanceId": "d9bd213c-0af5-11e6-9abd-64006a4c56ef",
"paramTypeId": "BBP-002001"
}
],
"localizer": {
"location": 22096,
"text": "Size and shape of PV-positive\ncells were typical of relay neurons (Fig. 3A). Analysis of\nPV expression in dLGN slices and thalamic cell cultures\n(data not shown) indicated that 79\u00b11% (a total of 1687\ncells were counted on seven different slides) of thalamic\ncells and 100% of cultured relay neurons (a total of 49\nrelay neurons were identified in 12 different cultures)\nwere PV positive, respectively.",
"type": "text"
},
"parameters": [],
"pubId": "10.1007/s00424-004-1377-z",
"tags": [
{
"id": "NIFGA:birnlex_1595",
"name": "Dorsal nucleus of lateral geniculate body"
},
{
"id": "NIFORG:nlx_organ_20081201",
"name": "Long Evans Rat"
},
{
"id": "NIFGA:birnlex_1595",
"name": "Dorsal nucleus of lateral geniculate body"
},
{
"id": "NIFORG:nlx_organ_20081201",
"name": "Long Evans Rat"
}
],
"version": "1"
}
]