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sample.yaml
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sample.yaml
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- directed: true
graph:
disease: Keratitis
disease_mesh: MESH:D007634
drug: cortisone acetate
drug_mesh: MESH:D003348
drugbank: DB:DB01380
links:
- key: increases activity of
source: MESH:D003348
target: UniProt:P04150
- key: negatively regulates
source: UniProt:P04150
target: UniProt:P23219
- key: increases abundance of
source: UniProt:P23219
target: MESH:D011453
- key: located in
source: MESH:D011453
target: GO:0006954
- key: causes
source: GO:0006954
target: MESH:D007634
multigraph: true
nodes:
- id: MESH:D003348
label: Drug
name: cortisone acetate
- id: UniProt:P04150
label: Protein
name: Glucocorticoid receptor
- id: UniProt:P23219
label: Protein
name: COX genes
- id: MESH:D011453
label: ChemicalSubstance
name: Prostaglandins
- id: GO:0006954
label: BiologicalProcess
name: Inflammation
- id: MESH:D007634
label: Disease
name: Keratitis
reference: https://go.drugbank.com/drugs/DB01380#mechanism-of-action