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DESCRIPTION
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DESCRIPTION
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Package: joineR
Type: Package
Title: Joint Modelling of Repeated Measurements and Time-to-Event Data
Version: 1.2.2
Authors@R: c(
person("Pete", "Philipson", email = "[email protected]",
role = "aut"),
person("Ines", "Sousa", email = "[email protected]",
role = "aut"),
person("Peter J.", "Diggle", email = "[email protected]",
role = "aut"),
person("Paula", "Williamson", email = "[email protected]",
role = "aut"),
person("Ruwanthi", "Kolamunnage-Dona", email = "[email protected]",
role = "aut"),
person("Robin", "Henderson", email = "[email protected]",
role = "aut"),
person("Graeme L.", "Hickey", email = "[email protected]",
role = c("aut", "cre")),
person("Maria", "Sudell", email = "[email protected]",
role = "ctb")
)
Encoding: UTF-8
Maintainer: Graeme L. Hickey <[email protected]>
Description: Analysis of repeated measurements and time-to-event data via random
effects joint models. Fits the joint models proposed by Henderson and colleagues
<doi:10.1093/biostatistics/1.4.465> (single event time) and by Williamson and
colleagues (2008) <doi:10.1002/sim.3451> (competing risks events time) to a
single continuous repeated measure. The time-to-event data is modelled using a
(cause-specific) Cox proportional hazards regression model with time-varying
covariates. The longitudinal outcome is modelled using a linear mixed effects
model. The association is captured by a latent Gaussian process. The model is
estimated using am Expectation Maximization algorithm. Some plotting functions
and the variogram are also included. This project is funded by the Medical
Research Council (Grant numbers G0400615 and MR/M013227/1).
License: GPL-3 | file LICENSE
URL: https://github.com/graemeleehickey/joineR/
BugReports: https://github.com/graemeleehickey/joineR/issues
LazyData: true
ByteCompile: true
Depends:
R (>= 3.1),
survival
Imports:
graphics,
lattice,
MASS,
nlme,
statmod,
stats,
utils
Suggests:
knitr,
rmarkdown,
testthat,
covr
VignetteBuilder: knitr
RoxygenNote: 6.0.1