diff --git a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.cpp b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.cpp
index 3d199351be5ef..2922d08ef8834 100644
--- a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.cpp
+++ b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.cpp
@@ -77,6 +77,7 @@ QWidget* SymbolTreeValueDelegate::createEditor(QWidget* parent, const QStyleOpti
 					{
 						QCheckBox* editor = new QCheckBox(parent);
 						editor->setChecked(value.toBool());
+						connect(editor, &QCheckBox::checkStateChanged, this, &SymbolTreeValueDelegate::onCheckBoxStateChanged);
 						result = editor;
 
 						break;
@@ -276,6 +277,13 @@ void SymbolTreeValueDelegate::setModelData(QWidget* editor, QAbstractItemModel*
 		model->setData(index, value, SymbolTreeModel::EDIT_ROLE);
 }
 
+void SymbolTreeValueDelegate::onCheckBoxStateChanged(Qt::CheckState state)
+{
+	QCheckBox* check_box = qobject_cast<QCheckBox*>(sender());
+	if (check_box)
+		commitData(check_box);
+}
+
 void SymbolTreeValueDelegate::onComboBoxIndexChanged(int index)
 {
 	QComboBox* combo_box = qobject_cast<QComboBox*>(sender());
diff --git a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.h b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.h
index 934727fe73146..03028297c5952 100644
--- a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.h
+++ b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeDelegates.h
@@ -21,8 +21,10 @@ class SymbolTreeValueDelegate : public QStyledItemDelegate
 	void setModelData(QWidget* editor, QAbstractItemModel* model, const QModelIndex& index) const override;
 
 protected:
-	// Without this, setModelData would only be called when a combo box was
-	// deselected rather than when an option was picked.
+	// These make it so the values inputted are written back to memory
+	// immediately when the widgets are interacted with rather than when they
+	// are deselected.
+	void onCheckBoxStateChanged(Qt::CheckState state);
 	void onComboBoxIndexChanged(int index);
 
 	DebugInterface& m_cpu;
diff --git a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeModel.cpp b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeModel.cpp
index b7c10901cebea..b7cf365b46464 100644
--- a/pcsx2-qt/Debugger/SymbolTree/SymbolTreeModel.cpp
+++ b/pcsx2-qt/Debugger/SymbolTree/SymbolTreeModel.cpp
@@ -484,6 +484,9 @@ std::vector<std::unique_ptr<SymbolTreeNode>> SymbolTreeModel::populateChildren(
 		}
 	}
 
+	for (std::unique_ptr<SymbolTreeNode>& child : children)
+		child->readFromVM(cpu, database);
+
 	return children;
 }