Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Kinase annotations question #12

Open
ravitharakan opened this issue Sep 12, 2022 · 0 comments
Open

Kinase annotations question #12

ravitharakan opened this issue Sep 12, 2022 · 0 comments

Comments

@ravitharakan
Copy link

Hi Hani and team, thank you for making such a useful package! I have a question about the PhosphoSitePlus annotations. It seems for many kinases, there are only a few annotated phosphosites. For example for mouse JAK1, a kinase we are interested in, the annotation is only

PhosphoSite.mouse$JAK1
[1] "STAT3;Y705;" "PTPN11;Y327;" "PTPN11;Y304;" "IL7R;Y449;"

JAK1 is known to phosphorylate STAT1 and STAT2, so it is surprising those annotations are not there. How are the annotations derived from PhosphoSitePlus? Can they be extended?

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant