diff --git a/newsfragments/4814.fixed.md b/newsfragments/4814.fixed.md
new file mode 100644
index 00000000000..6634efc2b9f
--- /dev/null
+++ b/newsfragments/4814.fixed.md
@@ -0,0 +1 @@
+`derive(FromPyObject)` support raw identifiers like `r#box`.
\ No newline at end of file
diff --git a/pyo3-macros-backend/src/frompyobject.rs b/pyo3-macros-backend/src/frompyobject.rs
index 14c8755e9be..565c54da1f3 100644
--- a/pyo3-macros-backend/src/frompyobject.rs
+++ b/pyo3-macros-backend/src/frompyobject.rs
@@ -3,6 +3,7 @@ use crate::utils::Ctx;
 use proc_macro2::TokenStream;
 use quote::{format_ident, quote};
 use syn::{
+    ext::IdentExt,
     parenthesized,
     parse::{Parse, ParseStream},
     parse_quote,
@@ -323,11 +324,11 @@ impl<'a> Container<'a> {
     fn build_struct(&self, struct_fields: &[NamedStructField<'_>], ctx: &Ctx) -> TokenStream {
         let Ctx { pyo3_path, .. } = ctx;
         let self_ty = &self.path;
-        let struct_name = &self.name();
-        let mut fields: Punctuated<TokenStream, syn::Token![,]> = Punctuated::new();
+        let struct_name = self.name();
+        let mut fields: Punctuated<TokenStream, Token![,]> = Punctuated::new();
         for field in struct_fields {
-            let ident = &field.ident;
-            let field_name = ident.to_string();
+            let ident = field.ident;
+            let field_name = ident.unraw().to_string();
             let getter = match field.getter.as_ref().unwrap_or(&FieldGetter::GetAttr(None)) {
                 FieldGetter::GetAttr(Some(name)) => {
                     quote!(#pyo3_path::types::PyAnyMethods::getattr(obj, #pyo3_path::intern!(obj.py(), #name)))
diff --git a/tests/test_frompyobject.rs b/tests/test_frompyobject.rs
index 344a47acf72..2192caf1f7c 100644
--- a/tests/test_frompyobject.rs
+++ b/tests/test_frompyobject.rs
@@ -648,3 +648,41 @@ fn test_transparent_from_py_with() {
         assert_eq!(result, expected);
     });
 }
+
+#[derive(Debug, FromPyObject, PartialEq, Eq)]
+pub struct WithKeywordAttr {
+    r#box: usize,
+}
+
+#[pyclass]
+pub struct WithKeywordAttrC {
+    #[pyo3(get)]
+    r#box: usize,
+}
+
+#[test]
+fn test_with_keyword_attr() {
+    Python::with_gil(|py| {
+        let cls = WithKeywordAttrC { r#box: 3 }.into_pyobject(py).unwrap();
+        let result = cls.extract::<WithKeywordAttr>().unwrap();
+        let expected = WithKeywordAttr { r#box: 3 };
+        assert_eq!(result, expected);
+    });
+}
+
+#[derive(Debug, FromPyObject, PartialEq, Eq)]
+pub struct WithKeywordItem {
+    #[pyo3(item)]
+    r#box: usize,
+}
+
+#[test]
+fn test_with_keyword_item() {
+    Python::with_gil(|py| {
+        let dict = PyDict::new(py);
+        dict.set_item("box", 3).unwrap();
+        let result = dict.extract::<WithKeywordItem>().unwrap();
+        let expected = WithKeywordItem { r#box: 3 };
+        assert_eq!(result, expected);
+    });
+}