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release notes for v1.4
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zakandrewking committed Oct 9, 2017
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2 changes: 1 addition & 1 deletion bigg_models/static/css/frontpage.css
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3 changes: 2 additions & 1 deletion bigg_models/templates/index.html
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Expand Up @@ -87,7 +87,8 @@ <h1 class="title">BiGG Models</h1>
<div class="col-lg-12">
<div class="well well-sm updates-link">
<a href="updates">
<i><b>Latest update</b></i>&nbsp;&nbsp;&nbsp;Version 1.3: Introducing the <i>i</i>CHO model
<i><b>Latest update</b></i>
&nbsp;&nbsp;Version 1.4: New <i>E.&nbsp;coli</i> model <i>i</i>ML1515, and more!
</a>
</div>
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38 changes: 38 additions & 0 deletions bigg_models/templates/updates.html
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{% block content %}
<h1 class="centered">Updates</h1>
<br/>
<h2>Version 1.4: Four new models, including the latest for <i>E.&nbsp;coli</i> K-12 MG1655</h2>
<p>
<i>Oct. 10, 2017</i>
</p>
<p>
Version 1.4 introduces four models to BiGG, including the latest
genome-scale model of <i>Escherichia coli</i> K-12 MG1655 from the Systems
Biology Research Group at UCSD. In addition, a new universal model can be
downloaded in JSON format from the <a href="/data_access">Data Access</a>
page, and a number of <a
href="https://github.com/SBRG/bigg_models/releases/tag/v1.4.0">bug fixes and
improvements</a> are included.
</p>
<p>
To account for newly discovered metabolic capabilities in
<i>E.&nbsp;coli</i> K-12 MG1655, Monk and Lloyd et al. have developed an
updated genome-scale model, <a href="/models/iML1515"><i>i</i>ML1515</a>,
that bridges systems and
structural biology. The new model was extensively validated using omics
datasets and boasts a 3.7% improvement in gene essentiality predictions over
the previous model, <i>i</i>JO1366, along with 184 new genes and 196 new
reactions. Check out the manuscript to see how this model can be applied to
analyze the metabolic capabilities <i>E.&nbsp;coli</i> strains in
metagenomic samples or used to build draft reconstructions of freshly
sequenced clinical isolates.
</p>
<p>
Other new models are: <a href="/models/iLB1027_lipid"><i>i</i>LB1027_lipid</a>
for <i>Phaeodactylum tricornutum</i> described by <a
href="http://www.ncbi.nlm.nih.gov/pubmed/27152931">Levering et al.</a>,
<a href="/models/iJB785"><i>i</i>JB785</a> for <i>Synechococcus elongatus</i> described by
<a href="http://www.ncbi.nlm.nih.gov/pubmed/27911809">Broddrick et al.</a>,
and <a href="/models/iNF517"><i>i</i>NF517</a> for <i>Lactococcus lactis</i> described by
<a href="http://www.ncbi.nlm.nih.gov/pubmed/23974365">Flahaut et al.</a>.
</p>
<a href="https://github.com/SBRG/bigg_models/releases/tag/v1.4.0">Github Release</a>
<br/>
<br/>
<h2>Version 1.3: Introducing the <i>i</i>CHO model</h2>
<p>
<i>Nov. 23, 2016</i>
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