From 1299361bd0a6f61b59f7a89ae2427a6ea6ac40f4 Mon Sep 17 00:00:00 2001
From: TanskaAnnna <TanskaAnnna@users.noreply.github.com>
Date: Fri, 21 May 2021 18:54:04 +0000
Subject: [PATCH] Commit from GitHub Actions (Update Indications on Merge)

---
 indication_paths.json | 64 +++++++++++++++++++++++++++++++++++++++++++
 indication_paths.yaml | 40 +++++++++++++++++++++++++++
 submission.yaml       | 39 +-------------------------
 3 files changed, 105 insertions(+), 38 deletions(-)

diff --git a/indication_paths.json b/indication_paths.json
index 040d5a68d..4cdee8635 100644
--- a/indication_paths.json
+++ b/indication_paths.json
@@ -195516,5 +195516,69 @@
     "reference": [
       "https://go.drugbank.com/drugs/DB09245"
     ]
+  },
+  {
+    "directed": true,
+    "graph": {
+      "_id": "DB00792_MESH_D065631_3",
+      "disease": "Allergic rhinitis",
+      "disease_mesh": "MESH:D065631",
+      "drug": "loratadine",
+      "drug_mesh": "MESH:D017336",
+      "drugbank": "DB:DB00792"
+    },
+    "links": [
+      {
+        "key": "decreases activity of",
+        "source": "MESH:D017336",
+        "target": "UniProt:P35367"
+      },
+      {
+        "key": "positively regulates",
+        "source": "UniProt:P35367",
+        "target": "GO:0004969"
+      },
+      {
+        "key": "positively correlated with",
+        "source": "GO:0004969",
+        "target": "GO:0002441"
+      },
+      {
+        "key": "positively correlated with",
+        "source": "GO:0002441",
+        "target": "MESH:D065631"
+      }
+    ],
+    "multigraph": true,
+    "nodes": [
+      {
+        "id": "MESH:D017336",
+        "label": "Drug",
+        "name": "loratadine"
+      },
+      {
+        "id": "UniProt:P35367",
+        "label": "Protein",
+        "name": "Histamine H1 receptor"
+      },
+      {
+        "id": "GO:0004969",
+        "label": "MolecularActivity",
+        "name": "histamine receptor activity"
+      },
+      {
+        "id": "GO:0002441",
+        "label": "BiologicalProcess",
+        "name": "histamine secretion involved in inflammatory response"
+      },
+      {
+        "id": "MESH:D065631",
+        "label": "Disease",
+        "name": "Allergic rhinitis"
+      }
+    ],
+    "reference": [
+      "https://go.drugbank.com/drugs/DB00455"
+    ]
   }
 ]
\ No newline at end of file
diff --git a/indication_paths.yaml b/indication_paths.yaml
index f8abfd828..77ea5277f 100644
--- a/indication_paths.yaml
+++ b/indication_paths.yaml
@@ -122909,3 +122909,43 @@
         name: Depressive disorder
     reference:
     - https://go.drugbank.com/drugs/DB09245
+-   directed: true
+    graph:
+        _id: DB00792_MESH_D065631_3
+        disease: Allergic rhinitis
+        disease_mesh: MESH:D065631
+        drug: loratadine
+        drug_mesh: MESH:D017336
+        drugbank: DB:DB00792
+    links:
+    -   key: decreases activity of
+        source: MESH:D017336
+        target: UniProt:P35367
+    -   key: positively regulates
+        source: UniProt:P35367
+        target: GO:0004969
+    -   key: positively correlated with
+        source: GO:0004969
+        target: GO:0002441
+    -   key: positively correlated with
+        source: GO:0002441
+        target: MESH:D065631
+    multigraph: true
+    nodes:
+    -   id: MESH:D017336
+        label: Drug
+        name: loratadine
+    -   id: UniProt:P35367
+        label: Protein
+        name: Histamine H1 receptor
+    -   id: GO:0004969
+        label: MolecularActivity
+        name: histamine receptor activity
+    -   id: GO:0002441
+        label: BiologicalProcess
+        name: histamine secretion involved in inflammatory response
+    -   id: MESH:D065631
+        label: Disease
+        name: Allergic rhinitis
+    reference:
+    - https://go.drugbank.com/drugs/DB00455
diff --git a/submission.yaml b/submission.yaml
index 0287a4c38..8b1378917 100644
--- a/submission.yaml
+++ b/submission.yaml
@@ -1,38 +1 @@
-- directed: true
-  graph:
-    disease: Allergic rhinitis
-    disease_mesh: MESH:D065631
-    drug: loratadine
-    drug_mesh: MESH:D017336
-    drugbank: DB:DB00792
-  links:
-    - key: decreases activity of
-      source: MESH:D017336
-      target: UniProt:P35367
-    - key: positively regulates
-      source: UniProt:P35367
-      target: GO:0004969
-    - key: positively correlated with
-      source: GO:0004969
-      target: GO:0002441
-    - key: positively correlated with
-      source: GO:0002441
-      target: MESH:D065631
-  multigraph: true
-  nodes:
-    - id: MESH:D017336
-      label: Drug
-      name: loratadine
-    - id: UniProt:P35367
-      label: Protein
-      name: Histamine H1 receptor
-    - id: GO:0004969
-      label: MolecularActivity
-      name: histamine receptor activity
-    - id: GO:0002441
-      label: BiologicalProcess
-      name: histamine secretion involved in inflammatory response
-    - id: MESH:D065631
-      label: Disease
-      name: Allergic rhinitis
-  reference: https://go.drugbank.com/drugs/DB00455
+