diff --git a/submission.yaml b/submission.yaml
index fa6e84f4b..b3e65e3d0 100644
--- a/submission.yaml
+++ b/submission.yaml
@@ -936,202 +936,6 @@
         name: Cystinuria
     reference:
     - https://go.drugbank.com/drugs/DB00859
--   comment: gabapentin enacarbil is a prodrug of gabapentin, it's physiological effects are the same as gabapentin
-    directed: true
-    graph:
-        disease: Postherpetic neuralgia
-        disease_mesh: MESH:D051474
-        drug: gabapentin enacarbil
-        drug_mesh: MESH:C493250
-        drugbank: DB:DB08872
-    links:
-    -   key: has metabolite
-        source: MESH:C493250
-        target: CHEBI:42797
-    -   key: decreases activity of
-        source: CHEBI:42797
-        target: UniProt:Q9NY47
-    -   key: decreases molecular interaction
-        source: UniProt:Q9NY47
-        target: InterPro:IPR018882
-    -   key: decreases expression of
-        source: InterPro:IPR018882
-        target: UniProt:Q00975
-    -   key: decreases molecular interaction
-        source: UniProt:Q9NY47
-        target: InterPro:IPR037440
-    -   key: decreases expression of
-        source: InterPro:IPR037440
-        target: UniProt:Q00975
-    -   key: decreases molecular interaction
-        source: UniProt:Q9NY47
-        target: InterPro:IPR000884
-    -   key: decreases expression of
-        source: InterPro:IPR000884
-        target: UniProt:Q00975
-    -   key: located in
-        source: UniProt:Q00975
-        target: GO:0098793
-    -   key: regulates
-        source: GO:0098793
-        target: GO:0015278
-    -   key: regulates
-        source: GO:0015278
-        target: GO:0007269
-    -   key: regulates
-        source: GO:0098793
-        target: GO:0005262
-    -   key: regulates
-        source: GO:0005262
-        target: GO:0007269
-    -   key: ameliorates
-        source: GO:0007269
-        target: HP:0012531
-    -   key: correlated with
-        source: HP:0012531
-        target: MESH:D051474
-    multigraph: true
-    nodes:
-    -   id: MESH:C493250
-        label: Drug
-        name: gabapentin enacarbil
-    -   id: CHEBI:42797
-        label: ChemicalSubstance
-        name: gabapentin
-    -   id: UniProt:Q9NY47
-        label: Protein
-        name: Voltage-dependent calcium channel subunit alpha-2/delta-2
-    -   id: InterPro:IPR018882
-        label: GeneFamily
-        name: NMDA receptors
-    -   id: InterPro:IPR037440
-        label: GeneFamily
-        name: Neurexins
-    -   id: InterPro:IPR000884
-        label: GeneFamily
-        name: Thrombospondins
-    -   id: UniProt:Q00975
-        label: Protein
-        name: Voltage-gated calcium channels
-    -   id: GO:0098793
-        label: CellularComponent
-        name: Presynapse
-    -   id: GO:0015278
-        label: MolecularActivity
-        name: Calcium-release channel activity
-    -   id: GO:0005262
-        label: MolecularActivity
-        name: Calcium channel activity
-    -   id: GO:0007269
-        label: BiologicalProcess
-        name: Neurotransmitter release
-    -   id: HP:0012531
-        label: PhenotypicFeature
-        name: Pain
-    -   id: MESH:D051474
-        label: Disease
-        name: Postherpetic neuralgia
-    reference:
-    - https://go.drugbank.com/drugs/DB08872#BE0000691
-    - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874339/
--   comment: gabapentin enacarbil is a prodrug of gabapentin, it's physiological effects are the same as gabapentin
-    directed: true
-    graph:
-        disease: Restless legs
-        disease_mesh: MESH:D012148
-        drug: gabapentin enacarbil
-        drug_mesh: MESH:C493250
-        drugbank: DB:DB08872
-    links:
-    -   key: has metabolite
-        source: MESH:C493250
-        target: CHEBI:42797
-    -   key: decreases activity of
-        source: CHEBI:42797
-        target: UniProt:Q9NY47
-    -   key: decreases molecular interaction
-        source: UniProt:Q9NY47
-        target: InterPro:IPR018882
-    -   key: decreases expression of
-        source: InterPro:IPR018882
-        target: UniProt:Q00975
-    -   key: decreases molecular interaction
-        source: UniProt:Q9NY47
-        target: InterPro:IPR037440
-    -   key: decreases expression of
-        source: InterPro:IPR037440
-        target: UniProt:Q00975
-    -   key: decreases molecular interaction
-        source: UniProt:Q9NY47
-        target: InterPro:IPR000884
-    -   key: decreases expression of
-        source: InterPro:IPR000884
-        target: UniProt:Q00975
-    -   key: located in
-        source: UniProt:Q00975
-        target: GO:0098793
-    -   key: regulates
-        source: GO:0098793
-        target: GO:0015278
-    -   key: regulates
-        source: GO:0015278
-        target: GO:0007269
-    -   key: regulates
-        source: GO:0098793
-        target: GO:0005262
-    -   key: regulates
-        source: GO:0005262
-        target: GO:0007269
-    -   key: ameliorates
-        source: GO:0007269
-        target: HP:0012514
-    -   key: correlated with
-        source: HP:0012514
-        target: MESH:D012148
-    multigraph: true
-    nodes:
-    -   id: MESH:C493250
-        label: Drug
-        name: gabapentin enacarbil
-    -   id: CHEBI:42797
-        label: ChemicalSubstance
-        name: gabapentin
-    -   id: UniProt:Q9NY47
-        label: Protein
-        name: Voltage-dependent calcium channel subunit alpha-2/delta-2
-    -   id: InterPro:IPR018882
-        label: GeneFamily
-        name: NMDA receptors
-    -   id: InterPro:IPR037440
-        label: GeneFamily
-        name: Neurexins
-    -   id: InterPro:IPR000884
-        label: GeneFamily
-        name: Thrombospondins
-    -   id: UniProt:Q00975
-        label: Protein
-        name: Voltage-gated calcium channels
-    -   id: GO:0098793
-        label: CellularComponent
-        name: Presynapse
-    -   id: GO:0015278
-        label: MolecularActivity
-        name: Calcium-release channel activity
-    -   id: GO:0005262
-        label: MolecularActivity
-        name: Calcium channel activity
-    -   id: GO:0007269
-        label: BiologicalProcess
-        name: Neurotransmitter release
-    -   id: HP:0012514
-        label: PhenotypicFeature
-        name: Lower limb pain
-    -   id: MESH:D012148
-        label: Disease
-        name: Restless legs
-    reference:
-    - https://go.drugbank.com/drugs/DB08872#BE0000691
-    - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874339/
 -   directed: true
     graph:
         disease: Gastrointestinal stromal tumor