diff --git a/subsys/net/openthread/Kconfig.defconfig b/subsys/net/openthread/Kconfig.defconfig
index ea05e8bfae55..3eeec1e96c64 100644
--- a/subsys/net/openthread/Kconfig.defconfig
+++ b/subsys/net/openthread/Kconfig.defconfig
@@ -31,30 +31,6 @@ choice OPENTHREAD_IMPLEMENTATION
 	default OPENTHREAD_LIBRARY if OPENTHREAD_LIBRARY_AVAILABLE
 endchoice
 
-if SOC_NRF54H20_CPUAPP
-
-#To be removed
-config ENTROPY_TEST_PRNG
-	bool
-	default y
-
-#To be removed
-config IPC_SERVICE_BACKEND_RPMSG_SHMEM_RESET
-	bool
-	   default y
-
-#To be removed
-config MBOX
-	bool
-	default y
-
-#To be removed
-config MBOX_NRFX_IDS
-	bool
-	default y
-
-endif
-
 choice LIBC_IMPLEMENTATION
 	default NEWLIB_LIBC
 endchoice
@@ -108,7 +84,8 @@ config OPENTHREAD_MANUAL_START
 	default y
 
 choice OPENTHREAD_SECURITY
-	default OPENTHREAD_NRF_SECURITY_PSA_CHOICE if SOC_FAMILY_NORDIC_NRF
+	default OPENTHREAD_NRF_SECURITY_PSA_CHOICE if (SOC_FAMILY_NORDIC_NRF && !SOC_NRF54H20_CPUAPP)
+	default OPENTHREAD_NRF_SECURITY_CHOICE if SOC_NRF54H20_CPUAPP
 endchoice
 
 config MBEDTLS_SSL_PROTO_DTLS