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I am trying to use badMIXTURE but I have the following doubts:
1.- If I have already results from chomopainter in which I have used the -a option (all inds x all inds), and I want to use that for badMIXTURE, should I:
a) just sum chunks for all inds within the same pop, and generate a inds x pops matrix?
or
b) run again chromopainter this time using the -f option (inds x pops)?
2.- In addition, should I use the option in which all pops are D (donors) and R (recipients) ? or...
3.- should I select some pops as D and some as R (or D+R)? For this case, as a guide, imagine an ADMIXTURE plot with 3 pops in which popA is all red, popB is all green and popC is 50%green, 50%red. Should I select pops A and B as "only donors"? and C as "D and/or R"? Or shoud I use all pops as "D and R"?
I am asking because I think perhaps this could have an influence in the marginals, and consequently, in the inferences made from the badMIXTURE plots.
Thanks in advance
The text was updated successfully, but these errors were encountered:
Hello, has your issue been resolved? I have another question: which output file from chomopainter should I use as the input N x P matrix for badmixture?
Dear Dan
I am trying to use badMIXTURE but I have the following doubts:
1.- If I have already results from chomopainter in which I have used the -a option (all inds x all inds), and I want to use that for badMIXTURE, should I:
a) just sum chunks for all inds within the same pop, and generate a inds x pops matrix?
or
b) run again chromopainter this time using the -f option (inds x pops)?
2.- In addition, should I use the option in which all pops are D (donors) and R (recipients) ? or...
3.- should I select some pops as D and some as R (or D+R)? For this case, as a guide, imagine an ADMIXTURE plot with 3 pops in which popA is all red, popB is all green and popC is 50%green, 50%red. Should I select pops A and B as "only donors"? and C as "D and/or R"? Or shoud I use all pops as "D and R"?
I am asking because I think perhaps this could have an influence in the marginals, and consequently, in the inferences made from the badMIXTURE plots.
Thanks in advance
The text was updated successfully, but these errors were encountered: