diff --git a/Dockerfile b/Dockerfile
new file mode 100644
index 0000000..561dc0c
--- /dev/null
+++ b/Dockerfile
@@ -0,0 +1,62 @@
+FROM python:3.7.3-stretch
+
+RUN mkdir -p /usr/src/app
+WORKDIR /usr/src/app
+
+COPY requirements.txt /usr/src/app/
+RUN pip install --upgrade pip
+RUN pip3 install --no-cache-dir -r requirements.txt
+RUN apt-get update && apt-get install -y wget && apt-get install coreutils && apt-get install unzip  && apt-get install -y default-jre
+
+# Install GNormPlus
+RUN wget https://www.ncbi.nlm.nih.gov/CBBresearch/Lu/Demo/tmTools/download/GNormPlus/GNormPlusJava.zip \
+&& unzip GNormPlusJava.zip && rm GNormPlusJava.zip
+RUN wget -O /usr/src/app/GNormPlusJava/crfpp-0.58.tar.gz https://drive.google.com/uc?id=0B4y35FiV1wh7QVR6VXJ5dWExSTQ
+RUN tar xvfz /usr/src/app/GNormPlusJava/crfpp-0.58.tar.gz
+RUN cp -rf /usr/src/app/CRF++-0.58/* /usr/src/app/GNormPlusJava/CRF
+RUN cd /usr/src/app/GNormPlusJava/CRF/ && sh ./configure
+RUN cd /usr/src/app/GNormPlusJava/CRF/ && make 
+RUN cd /usr/src/app/GNormPlusJava/CRF/ && make install
+RUN chmod 764 /usr/src/app/GNormPlusJava/Ab3P
+RUN cd /usr/src/app/GNormPlusJava/ && sed -i 's/= All/= 9606/g' setup.txt; echo "FocusSpecies: from All to 9606 (Human)"
+RUN cd /usr/src/app/GNormPlusJava/ && sh Installation.sh
+RUN cd /usr/src/app/GNormPlusJava/ && wget --load-cookies /tmp/cookies.txt "https://docs.google.com/uc?export=download&confirm=$(wget --quiet --save-cookies /tmp/cookies.txt --keep-session-cookies --no-check-certificate 'https://docs.google.com/uc?export=download&id=1g-JlhqeDIlZX5YFk8Y27_M8BXUXcQRSX' -O- | sed -rn 's/.*confirm=([0-9A-Za-z_]+).*/\1\n/p')&id=1g-JlhqeDIlZX5YFk8Y27_M8BXUXcQRSX" -O GNormPlusServer.jar && rm -rf /tmp/cookies.txt
+
+# Install tmVar2
+RUN cd /usr/src/app/ && wget ftp://ftp.ncbi.nlm.nih.gov/pub/lu/Suppl/tmVar2/tmVarJava.zip \
+&& unzip tmVarJava.zip  && rm tmVarJava.zip
+RUN cp -rf /usr/src/app/CRF++-0.58/* /usr/src/app/tmVarJava/CRF && rm -R /usr/src/app/CRF++-0.58 && rm /usr/src/app/GNormPlusJava/crfpp-0.58.tar.gz
+RUN cd /usr/src/app/tmVarJava/CRF/ && sh ./configure
+RUN cd /usr/src/app/tmVarJava/CRF/ && make 
+RUN cd /usr/src/app/tmVarJava/CRF/ && make install
+RUN chmod 764 /usr/src/app/tmVarJava/CRF/crf_test
+RUN cd /usr/src/app/tmVarJava/ && sh Installation.sh
+RUN cd /usr/src/app/tmVarJava/ && wget --load-cookies /tmp/cookies.txt "https://docs.google.com/uc?export=download&confirm=$(wget --quiet --save-cookies /tmp/cookies.txt --keep-session-cookies --no-check-certificate 'https://docs.google.com/uc?export=download&id=1kQYzLHLFLsU9qKpRRGjXkIYmaYK6bPJm' -O- | sed -rn 's/.*confirm=([0-9A-Za-z_]+).*/\1\n/p')&id=1kQYzLHLFLsU9qKpRRGjXkIYmaYK6bPJm" -O tmVar2Server.jar && rm -rf /tmp/cookies.txt
+RUN cd /usr/src/app/tmVarJava/ && wget https://repo1.maven.org/maven2/org/xerial/sqlite-jdbc/3.20.0/sqlite-jdbc-3.20.0.jar
+RUN cd /usr/src/app/tmVarJava/ && wget https://repo1.maven.org/maven2/edu/stanford/nlp/stanford-corenlp/3.5.2/stanford-corenlp-3.5.2.jar
+
+# Copy Project into App
+COPY . /usr/src/app
+RUN mkdir /usr/src/app/logs
+RUN touch /usr/src/app/logs/nohup_BERN.out \
+&& touch /usr/src/app/logs/nohup_disease_normalize.out \
+&& touch /usr/src/app/logs/nohup_drug_normalize.out \
+&& touch /usr/src/app/logs/nohup_gene_normalize.out \
+&& touch /usr/src/app/logs/nohup_gnormplus.out \
+&& touch /usr/src/app/logs/nohup_mutation_normalize.out \
+&& touch /usr/src/app/logs/nohup_species_normalize.out \
+&& touch /usr/src/app/logs/nohup_tmvar.out
+
+# Download normalization resources and pre-trained BioBERT NER models
+RUN cd /usr/src/app/scripts && sh download_norm.sh \
+&& cd /usr/src/app/scripts && sh download_biobert_ner_models.sh
+
+EXPOSE 8888
+
+# Execute
+CMD (cd /usr/src/app/GNormPlusJava/ && nohup java -Xmx16G -Xms16G -jar /usr/src/app/GNormPlusJava/GNormPlusServer.jar 18895 >> /usr/src/app/logs/nohup_gnormplus.out 2>&1 &) \
+&& (cd /usr/src/app/tmVarJava/ && nohup java -Xmx8G -Xms8G -jar /usr/src/app/tmVarJava/tmVar2Server.jar 18896 >> /usr/src/app/logs/nohup_tmvar.out 2>&1 &) \
+&& (cd /usr/src/app/ && sh load_dicts.sh) \
+&& echo $CUDA_VISIBLE_DEVICES && export CUDA_VISIBLE_DEVICES=0 \
+&& (nohup python3 -u /usr/src/app/server.py --port 8888 --gnormplus_home /usr/src/app/GNormPlusJava --gnormplus_port 18895 --tmvar2_home /usr/src/app/tmVarJava --tmvar2_port 18896 >> /usr/src/app/logs/nohup_BERN.out 2>&1 &) \
+&& tail -f logs/nohup_BERN.out
\ No newline at end of file
diff --git a/README.md b/README.md
index 4d25b96..9c0fd9e 100644
--- a/README.md
+++ b/README.md
@@ -160,6 +160,12 @@ tail -F logs/nohup_BERN.out
         print(result_dict)
         ```
 
+## BERN in Docker
+
+Build and run BERN in a single container::
+
+    docker build --tag bern_service_component:1.0 . && docker run --publish 8888:8888 --detach --name bern bern_service_component:1.0
+
 ## Result
 <details>
     <summary>See a result example in JSON (PMID:29446767) </summary>
@@ -347,7 +353,6 @@ nohup python3 -u server.py --port 8888 --gnormplus_home ~/bern/GNormPlusJava --g
 tail -F logs/nohup_BERN.out
 ```
 
-
 ## Troubleshooting
 * Trouble: It takes a long time to get results. 
     * Solution: Make sure TensorFlow is using a GPU.
diff --git a/requirements.txt b/requirements.txt
index 54c71db..67f2b15 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,5 +1,5 @@
-numpy
-pandas
-requests
-tensorflow-gpu
-xmltodict
+numpy==1.19.2
+pandas==1.1.3
+requests==2.24.0
+tensorflow-gpu==1.15
+xmltodict==0.12.0