[BUG] Dotnet profiler auto instrument not working

[ysj2018]

I would like to use dotnet Profiler Auto instrumentation to probe my test application developed based on the .NET Framework, but it's not working.

Details about my application:

The test application is developed using .NET Framework 4.8.1.
It runs normally and functions correctly.
Details about my computer:

My computer's operating system is Windows 11.
The pre-installed .NET Framework version on my computer is 4.8.
Details about my development environment:

I use Rider 2024 as my development tool.
When creating the project, the target framework selected was 4.8.1.
When building the project, v4.0 was chosen.
For publishing, I chose a local folder.
I packaged and published the project on IIS and configured environment variables with the script as follows:

$appcmd = "$($env:systemroot)\system32\inetsrv\AppCmd.exe"
$appPool = "test"
$profilerHomeDir = "D:\IIS\agent\agent"
$environment = @{
COR_ENABLE_PROFILING = "1"
COR_PROFILER = "{FA65FE15-F085-4681-9B20-95E04F6C03CC}"
COR_PROFILER_PATH = "$profilerHomeDir\elastic_apm_profiler.dll"
ELASTIC_APM_PROFILER_HOME = "$profilerHomeDir"
ELASTIC_APM_PROFILER_INTEGRATIONS = "$profilerHomeDir\integrations.yml"
COMPlus_LoaderOptimization = "1"
ELASTIC_APM_SERVER_URL = "http://localhost:8200"
ELASTIC_APM_SERVICE_NAME = "dotnettest"
}
$environment.Keys | ForEach-Object {
& $appcmd set config -section:system.applicationHost/applicationPools /+"[name='$appPool'].environmentVariables.[name='$',value='$($environment[$])']"
}

The project runs normally, but the profiler did not successfully attach.

An error was found in the Event Viewer: "NET Runtime version 4.0.30319.0 - Failed to load profiler during CoCreateInstance. Profiler CLSID: '{FA65FE15-F085-4681-9B20-95E04F6C03CC}'. HRESULT: 0x800700c1. Process ID (decimal): 26524. Message ID: [0x2504]."

What could be the possible reasons for this?