diff --git a/CMakeLists.txt b/CMakeLists.txt
index 8d5ac0ad1..212e3eec3 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -32,14 +32,16 @@ if(NOT SILKWORM_HAS_PARENT)
         CACHE FILEPATH "" FORCE
     )
   endif()
-
-  include(cmake/conan.cmake)
-
 endif()
 
 project(silkworm)
 set(PROJECT_VERSION 0.1.0-dev)
 
+# conan must be initiailzed after project definition to properly detect target architecture.
+if(NOT SILKWORM_HAS_PARENT)
+  include(cmake/conan.cmake)
+endif()
+
 include(CableBuildInfo)
 
 string(REGEX MATCH "([0-9]+)\\.([0-9]+)\\.([0-9]+)" _ ${PROJECT_VERSION})
diff --git a/cmake/conan.cmake b/cmake/conan.cmake
index 3f5afacd6..187e65968 100644
--- a/cmake/conan.cmake
+++ b/cmake/conan.cmake
@@ -16,7 +16,11 @@
 
 function(guess_conan_profile)
   if(CMAKE_HOST_SYSTEM_NAME STREQUAL "Linux")
-    set(PROFILE linux_gcc_11_release)
+    if(CMAKE_HOST_SYSTEM_PROCESSOR STREQUAL "aarch64")
+      set(PROFILE linux_arm_gcc_11_release)
+    else()
+      set(PROFILE linux_gcc_11_release)
+    endif()
   elseif(CMAKE_HOST_SYSTEM_NAME STREQUAL "Darwin")
     if(CMAKE_OSX_ARCHITECTURES STREQUAL "arm64")
       set(PROFILE macos_arm_clang_13_release)
diff --git a/cmake/profiles/linux_arm_gcc_11_debug b/cmake/profiles/linux_arm_gcc_11_debug
new file mode 100644
index 000000000..93d21f94c
--- /dev/null
+++ b/cmake/profiles/linux_arm_gcc_11_debug
@@ -0,0 +1,12 @@
+[settings]
+os=Linux
+os_build=Linux
+arch=armv8
+arch_build=armv8
+compiler=gcc
+compiler.version=11
+compiler.libcxx=libstdc++11
+build_type=Debug
+[options]
+[build_requires]
+[env]
diff --git a/cmake/profiles/linux_arm_gcc_11_release b/cmake/profiles/linux_arm_gcc_11_release
new file mode 100644
index 000000000..2222f4639
--- /dev/null
+++ b/cmake/profiles/linux_arm_gcc_11_release
@@ -0,0 +1,12 @@
+[settings]
+os=Linux
+os_build=Linux
+arch=armv8
+arch_build=armv8
+compiler=gcc
+compiler.version=11
+compiler.libcxx=libstdc++11
+build_type=Release
+[options]
+[build_requires]
+[env]
diff --git a/silkworm/silkrpc/commands/ots_api.cpp b/silkworm/silkrpc/commands/ots_api.cpp
index 22e213e55..bdc696e48 100644
--- a/silkworm/silkrpc/commands/ots_api.cpp
+++ b/silkworm/silkrpc/commands/ots_api.cpp
@@ -34,6 +34,13 @@
 #include <silkworm/silkrpc/ethdb/transaction_database.hpp>
 #include <silkworm/silkrpc/json/types.hpp>
 
+// GCC in this setting will report mismatch in new delete when checking dtor of boost::asio::awaitable.
+// Possibly cuased by GCC process ctor as inline but not for dtor. https://gcc.gnu.org/bugzilla/show_bug.cgi?id=100485
+// Any more fine-grained fix will need toching the boost files. So we supress the warning here.
+// As for now, GCC does not report such warning in other architecture. So we can still rely on this check on other platform for protection.
+#ifdef __aarch64__
+#pragma GCC diagnostic ignored "-Wmismatched-new-delete"
+#endif
 namespace silkworm::rpc::commands {
 
 constexpr int kCurrentApiLevel{8};