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Cellular location based on PTN000038764 #5553

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rozaru opened this issue Nov 28, 2024 · 0 comments
Open

Cellular location based on PTN000038764 #5553

rozaru opened this issue Nov 28, 2024 · 0 comments
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@rozaru
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rozaru commented Nov 28, 2024

  • PTHR ID & PTN node:
    PTN000038764

  • Sequences with problematic annotation (ID + gene/protein name):
    Ids Q9VZP8
    Other genes affected

  • Type of Issue: Erroneous source or erroneous propagation, or other issue
    Ids is normally localised in the lysosome. The IBA annotation is cytoplasmic although is not incorrect, it's not precise.
    Both mouse and human have IDA for CC term lysosome
    The cytoplasmic annotation comes from zebrafish A1A5V0 (PMID:19761845). I have contacted them if they can amend their annotation as the paper shows that it's in the lysosome.

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