From 3a875381a32b55f45aa71ee4662f0cd0bc745845 Mon Sep 17 00:00:00 2001 From: Colby Chiang Date: Wed, 14 Dec 2016 10:44:57 -0600 Subject: [PATCH] FAQ to address #31 and #94 --- README.md | 5 +++++ 1 file changed, 5 insertions(+) diff --git a/README.md b/README.md index 43ea498..acdb788 100644 --- a/README.md +++ b/README.md @@ -630,6 +630,11 @@ SpeedSeq is available as a public AMI (Amazon Machine Image) on the Amazon Elast * example.vcf.gz * example.sv.vcf.gz +## Frequently asked questions (FAQ) + +* Can I use SpeedSeq on exome data? + * SpeedSeq can detect SNVs and indels from exome data using `speedseq var` or `speedseq somatic`. However, you should not use the [excluded regions](https://github.com/hall-lab/speedseq#annotations), as these were designed for WGS data. SpeedSeq cannot detect SVs from exome data. + ## Troubleshooting If you encounter errors or strange behavior from SpeedSeq, please report them to the [issues](https://github.com/hall-lab/speedseq/issues) page with the following information: