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ML applicataion on CRISPR data

Data source

GUIDEseq_allgRNAs_identified.csv: Output cleavage frequency and corresponding chromosomal position identified by GUIDE-seq technique with 10 different gRNAs. This table is the output table from guideseq package developed by jounglab.

CIRCLEseq_allgRNAs_identified_matched.txt: Output cleavage frequency and correspoinding chromoslmal position identifed by CIRCLE-seq technique with 10 different gRNAs. This table is the output table from circleseq package developed by jounglab.

gRNAs.casoff.scores.csv: Output potential off-target sites with less than 7 mismatches against gRNA sequence from input file gRNAs.casoff.input using published program cas-offinder. The listed 10 gRNAs in gRNAs.casoff.input was the 10 gRNAs examined in the GUIDE-seq and CIRCLE-seq papers.

Preprocessing

Analyses

Discussion

Features

  • TODO