-
Notifications
You must be signed in to change notification settings - Fork 1
/
README.Rmd
83 lines (57 loc) · 2.26 KB
/
README.Rmd
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
---
output: github_document
---
<!-- README.md is generated from README.Rmd. Please edit that file -->
```{r, include = FALSE}
knitr::opts_chunk$set(
collapse = TRUE,
comment = "#>",
fig.path = "man/figures/README-",
out.width = "100%"
)
```
# tmod <a href='https://january3.github.com/tmod/'><img src='man/figures/logo.png' align="right" height="138.5" /></a>
<!-- badges: start -->
[![R-CMD-check](https://github.com/january3/tmod/actions/workflows/R-CMD-check.yaml/badge.svg)](https://github.com/january3/tmod/actions/workflows/R-CMD-check.yaml)
[![test-coverage](https://github.com/january3/tmod/actions/workflows/test-coverage.yaml/badge.svg)](https://github.com/january3/tmod/actions/workflows/test-coverage.yaml)
[![CRAN status](https://www.r-pkg.org/badges/version/tmod)](https://CRAN.R-project.org/package=tmod)
<!-- badges: end -->
Tmod is a suite of gene set enrichment algorithms, visualizations and
utilities which comes bundled with a few libraries of gene sets
("modules"). Following features distinguish tmod from other packages:
* "panel plot" visualizations which allow to compare results of gene set
enrichments;
* several enrichment algorithms are implemented in tmod, in particular the
very efficient, versatile and
[reproducible](https://academic.oup.com/bioinformatics/article/35/24/5146/5511403)
algorithm called "CERNO";
* it includes a library of gene sets derived from clustering of gene
expression data from human blood, which is especially useful in
functional analysis in infection and immune responses.
## Installation
You can install the released version of tmod from [CRAN](https://CRAN.R-project.org/) with:
``` r
install.packages("tmod")
```
And the development version from [GitHub](https://github.com/) with:
``` r
# install.packages("devtools")
devtools::install_github("january3/tmod")
```
## Tmod manual
* Access the documentation using `vignette("tmod")`
* Full user manual is found [here](https://january3.github.io/tmod/articles/user_manual/tmod_user_manual.html)
## Example usage
```{r include=FALSE}
library(ggplot2)
library(cowplot)
theme_set(theme_minimal())
```
```{r}
library(tmod)
data(EgambiaResults)
tt <- EgambiaResults
## gene set enrichment analysis
res <- tmodCERNOtest(tt$GENE_SYMBOL)
head(res)
```