diff --git a/.changeset/quick-onions-guess.md b/.changeset/quick-onions-guess.md
new file mode 100644
index 000000000..f03afbb2a
--- /dev/null
+++ b/.changeset/quick-onions-guess.md
@@ -0,0 +1,8 @@
+---
+"@lens-protocol/domain": minor
+"@lens-protocol/react": minor
+"@lens-protocol/react-native": minor
+"@lens-protocol/react-web": minor
+---
+
+**feat:** added hooks to manage profile interests: useAddProfileInterests and useRemoveProfileInterests
diff --git a/examples/web/src/App.tsx b/examples/web/src/App.tsx
index e46ca615d..d3c5afd7d 100644
--- a/examples/web/src/App.tsx
+++ b/examples/web/src/App.tsx
@@ -51,6 +51,7 @@ import {
   UseProfileActionHistory,
   UseProfileFollowers,
   UseProfileFollowing,
+  UseProfileInterests,
   UseProfileManagers,
   UseProfiles,
   UseRecommendProfileToggle,
@@ -151,6 +152,7 @@ export function App() {
                   <Route path="useBlockedProfiles" element={<UseBlockedProfiles />} />
                   <Route path="useReportProfile" element={<UseReportProfile />} />
                   <Route path="useRecommendProfileToggle" element={<UseRecommendProfileToggle />} />
+                  <Route path="useProfileInterests" element={<UseProfileInterests />} />
                 </Route>
 
                 <Route path="/discovery">
diff --git a/examples/web/src/profiles/ProfilesPage.tsx b/examples/web/src/profiles/ProfilesPage.tsx
index d89f75f7a..1fd499ff3 100644
--- a/examples/web/src/profiles/ProfilesPage.tsx
+++ b/examples/web/src/profiles/ProfilesPage.tsx
@@ -96,6 +96,11 @@ const profileHooks = [
     description: 'Recommend a profile.',
     path: '/profiles/useRecommendProfileToggle',
   },
+  {
+    label: 'useProfileInterests',
+    description: 'Add and remove profile interests.',
+    path: '/profiles/useProfileInterests',
+  },
 ];
 
 export function ProfilesPage() {
diff --git a/examples/web/src/profiles/UseProfileInterests.tsx b/examples/web/src/profiles/UseProfileInterests.tsx
new file mode 100644
index 000000000..38e7b1787
--- /dev/null
+++ b/examples/web/src/profiles/UseProfileInterests.tsx
@@ -0,0 +1,122 @@
+import {
+  useAddProfileInterests,
+  useRemoveProfileInterests,
+  ProfileInterestTypes,
+  Profile,
+} from '@lens-protocol/react-web';
+import { Fragment, useMemo } from 'react';
+
+import { RequireProfileSession } from '../components/auth';
+
+// Capitalizes each word in a string
+function capitalize(label: string): string {
+  return label.toLowerCase().replace(/\b\w/g, (char) => char.toUpperCase());
+}
+
+type Interest = {
+  parent: string;
+  value: ProfileInterestTypes;
+  label: string;
+};
+
+// Processes raw interest types into structured interests array
+function createInterests(categories: ProfileInterestTypes[]): Interest[] {
+  return categories.map((item) => {
+    const [parent, subcategory] = item.split('__');
+    const label = capitalize(
+      subcategory ? subcategory.replace(/_/g, ' ') : parent.replace(/_/g, ' '),
+    );
+    return { parent, value: item, label };
+  });
+}
+
+type ButtonProps = {
+  isActive: boolean;
+  onClick: () => void;
+  children: React.ReactNode;
+};
+
+function ToggleButton({ isActive, onClick, children }: ButtonProps) {
+  const normalStyle = {
+    backgroundColor: 'transparent',
+    border: '1px solid grey',
+    color: '#111',
+    outline: 'none',
+  };
+
+  const activeStyle = {
+    ...normalStyle,
+    backgroundColor: '#333',
+    color: '#eee',
+  };
+
+  return (
+    <button style={isActive ? activeStyle : normalStyle} onClick={onClick}>
+      {children}
+    </button>
+  );
+}
+
+function UseProfileInterestsInner({ profile }: { profile: Profile }) {
+  const { execute: addInterests } = useAddProfileInterests();
+  const { execute: removeInterests } = useRemoveProfileInterests();
+
+  const groupedInterests = useMemo(() => {
+    const interests = createInterests(Object.values(ProfileInterestTypes));
+
+    // Group interests by category
+    return interests.reduce((acc, interest) => {
+      acc[interest.parent] = acc[interest.parent] || [];
+      acc[interest.parent].push(interest);
+      return acc;
+    }, {} as Record<string, Interest[]>);
+  }, []);
+
+  const handleClick = async (interest: ProfileInterestTypes) => {
+    const request = {
+      interests: [interest],
+    };
+
+    if (profile.interests.includes(interest)) {
+      await removeInterests(request);
+    } else {
+      await addInterests(request);
+    }
+  };
+
+  return (
+    <div>
+      {Object.entries(groupedInterests).map(([category, items]) => (
+        <div key={category}>
+          <h4>{capitalize(category.replace(/_/g, ' '))}</h4>
+          <div>
+            {items.map((item) => (
+              <Fragment key={item.value}>
+                <ToggleButton
+                  onClick={() => handleClick(item.value)}
+                  isActive={profile.interests.includes(item.value)}
+                >
+                  {item.label}
+                </ToggleButton>{' '}
+              </Fragment>
+            ))}
+          </div>
+        </div>
+      ))}
+    </div>
+  );
+}
+
+export function UseProfileInterests() {
+  return (
+    <div>
+      <h2>
+        <code>useAddProfileInterests & useRemoveProfileInterests</code>
+      </h2>
+
+      <RequireProfileSession message="Log in to view this example.">
+        {({ profile }) => <UseProfileInterestsInner profile={profile} />}
+      </RequireProfileSession>
+    </div>
+  );
+}
diff --git a/examples/web/src/profiles/index.ts b/examples/web/src/profiles/index.ts
index 315246fd1..999f42aca 100644
--- a/examples/web/src/profiles/index.ts
+++ b/examples/web/src/profiles/index.ts
@@ -10,6 +10,7 @@ export * from './UseProfile';
 export * from './UseProfileActionHistory';
 export * from './UseProfileFollowers';
 export * from './UseProfileFollowing';
+export * from './UseProfileInterests';
 export * from './UseProfileManagers';
 export * from './UseProfiles';
 export * from './UseRecommendProfileToggle';
diff --git a/packages/domain/src/use-cases/profile/ManageProfileInterests.ts b/packages/domain/src/use-cases/profile/ManageProfileInterests.ts
new file mode 100644
index 000000000..6bebae3ba
--- /dev/null
+++ b/packages/domain/src/use-cases/profile/ManageProfileInterests.ts
@@ -0,0 +1,30 @@
+export type ProfileInterestsRequest<T> = {
+  interests: T[];
+};
+
+export interface IProfileInterestsGateway<T> {
+  add(request: ProfileInterestsRequest<T>): Promise<void>;
+  remove(request: ProfileInterestsRequest<T>): Promise<void>;
+}
+
+export interface IProfileInterestsPresenter<T> {
+  add(request: ProfileInterestsRequest<T>): Promise<void>;
+  remove(request: ProfileInterestsRequest<T>): Promise<void>;
+}
+
+export class ManageProfileInterests<T> {
+  constructor(
+    private readonly gateway: IProfileInterestsGateway<T>,
+    private readonly presenter: IProfileInterestsPresenter<T>,
+  ) {}
+
+  async add(request: ProfileInterestsRequest<T>) {
+    void this.gateway.add(request);
+    await this.presenter.add(request);
+  }
+
+  async remove(request: ProfileInterestsRequest<T>) {
+    void this.gateway.remove(request);
+    await this.presenter.remove(request);
+  }
+}
diff --git a/packages/domain/src/use-cases/profile/index.ts b/packages/domain/src/use-cases/profile/index.ts
index 50a870255..1c3156114 100644
--- a/packages/domain/src/use-cases/profile/index.ts
+++ b/packages/domain/src/use-cases/profile/index.ts
@@ -5,6 +5,7 @@ export * from './DismissRecommendedProfiles';
 export * from './FollowPolicy';
 export * from './FollowProfile';
 export * from './LinkHandle';
+export * from './ManageProfileInterests';
 export * from './ReportProfile';
 export * from './SetProfileMetadata';
 export * from './ToggleProfileProperty';
diff --git a/packages/react/src/profile/adapters/ProfileInterestsGateway.ts b/packages/react/src/profile/adapters/ProfileInterestsGateway.ts
new file mode 100644
index 000000000..38292cca0
--- /dev/null
+++ b/packages/react/src/profile/adapters/ProfileInterestsGateway.ts
@@ -0,0 +1,41 @@
+import {
+  AddProfileInterestsData,
+  AddProfileInterestsDocument,
+  AddProfileInterestsVariables,
+  ProfileInterestTypes,
+  RemoveProfileInterestsData,
+  RemoveProfileInterestsDocument,
+  RemoveProfileInterestsVariables,
+  SafeApolloClient,
+} from '@lens-protocol/api-bindings';
+import { IProfileInterestsGateway } from '@lens-protocol/domain/use-cases/profile';
+
+export type ProfileInterestsRequest = {
+  interests: ProfileInterestTypes[];
+};
+
+export class ProfileInterestsGateway implements IProfileInterestsGateway<ProfileInterestTypes> {
+  constructor(private apolloClient: SafeApolloClient) {}
+
+  async add(request: ProfileInterestsRequest) {
+    await this.apolloClient.mutate<AddProfileInterestsData, AddProfileInterestsVariables>({
+      mutation: AddProfileInterestsDocument,
+      variables: {
+        request: {
+          interests: request.interests,
+        },
+      },
+    });
+  }
+
+  async remove(request: ProfileInterestsRequest) {
+    await this.apolloClient.mutate<RemoveProfileInterestsData, RemoveProfileInterestsVariables>({
+      mutation: RemoveProfileInterestsDocument,
+      variables: {
+        request: {
+          interests: request.interests,
+        },
+      },
+    });
+  }
+}
diff --git a/packages/react/src/profile/adapters/ProfileInterestsPresenter.ts b/packages/react/src/profile/adapters/ProfileInterestsPresenter.ts
new file mode 100644
index 000000000..ba275ead4
--- /dev/null
+++ b/packages/react/src/profile/adapters/ProfileInterestsPresenter.ts
@@ -0,0 +1,33 @@
+import { ProfileInterestTypes } from '@lens-protocol/api-bindings';
+import { ProfileId } from '@lens-protocol/domain/entities';
+import { IProfileInterestsPresenter } from '@lens-protocol/domain/use-cases/profile';
+
+import { IProfileCacheManager } from './IProfileCacheManager';
+import { ProfileInterestsRequest } from './ProfileInterestsGateway';
+
+export class ProfileInterestsPresenter implements IProfileInterestsPresenter<ProfileInterestTypes> {
+  constructor(
+    private readonly profileCacheManager: IProfileCacheManager,
+    private readonly profileId: ProfileId,
+  ) {}
+
+  async add(request: ProfileInterestsRequest) {
+    this.profileCacheManager.update(this.profileId, (current) => {
+      return {
+        ...current,
+        interests: [...current.interests, ...request.interests],
+      };
+    });
+  }
+
+  async remove(request: ProfileInterestsRequest) {
+    this.profileCacheManager.update(this.profileId, (current) => {
+      return {
+        ...current,
+        interests: current.interests.filter(
+          (interest) => !request.interests.includes(interest as ProfileInterestTypes),
+        ),
+      };
+    });
+  }
+}
diff --git a/packages/react/src/profile/adapters/useProfileInterestsController.ts b/packages/react/src/profile/adapters/useProfileInterestsController.ts
new file mode 100644
index 000000000..caef2029a
--- /dev/null
+++ b/packages/react/src/profile/adapters/useProfileInterestsController.ts
@@ -0,0 +1,43 @@
+import { ManageProfileInterests } from '@lens-protocol/domain/use-cases/profile';
+import { invariant } from '@lens-protocol/shared-kernel';
+
+import { SessionType, useSession } from '../../authentication';
+import { useSharedDependencies } from '../../shared';
+import { ProfileInterestsGateway, ProfileInterestsRequest } from './ProfileInterestsGateway';
+import { ProfileInterestsPresenter } from './ProfileInterestsPresenter';
+
+export function useProfileInterestsController() {
+  const { apolloClient, profileCacheManager } = useSharedDependencies();
+  const { data: session } = useSession();
+
+  const add = async (request: ProfileInterestsRequest) => {
+    invariant(
+      session?.type === SessionType.WithProfile,
+      'You must be authenticated with a profile to use this hook. Use `useLogin` hook to authenticate.',
+    );
+
+    const presenter = new ProfileInterestsPresenter(profileCacheManager, session.profile.id);
+    const gateway = new ProfileInterestsGateway(apolloClient);
+    const manageInterests = new ManageProfileInterests(gateway, presenter);
+
+    await manageInterests.add(request);
+  };
+
+  const remove = async (request: ProfileInterestsRequest) => {
+    invariant(
+      session?.type === SessionType.WithProfile,
+      'You must be authenticated with a profile to use this hook. Use `useLogin` hook to authenticate.',
+    );
+
+    const presenter = new ProfileInterestsPresenter(profileCacheManager, session.profile.id);
+    const gateway = new ProfileInterestsGateway(apolloClient);
+    const manageInterests = new ManageProfileInterests(gateway, presenter);
+
+    await manageInterests.remove(request);
+  };
+
+  return {
+    add,
+    remove,
+  };
+}
diff --git a/packages/react/src/profile/index.ts b/packages/react/src/profile/index.ts
index d5d0ebb4e..ae06b6d71 100644
--- a/packages/react/src/profile/index.ts
+++ b/packages/react/src/profile/index.ts
@@ -1,6 +1,7 @@
 /**
  * Hooks
  */
+export * from './useAddProfileInterests';
 export * from './useBlockedProfiles';
 export * from './useLazyProfile';
 export * from './useLazyProfiles';
@@ -12,6 +13,7 @@ export * from './useProfileFollowing';
 export * from './useProfileManagers';
 export * from './useProfiles';
 export * from './useRecommendProfileToggle';
+export * from './useRemoveProfileInterests';
 export * from './useReportProfile';
 export * from './useWhoActedOnPublication';
 
diff --git a/packages/react/src/profile/useAddProfileInterests.ts b/packages/react/src/profile/useAddProfileInterests.ts
new file mode 100644
index 000000000..6a5d6fe8f
--- /dev/null
+++ b/packages/react/src/profile/useAddProfileInterests.ts
@@ -0,0 +1,53 @@
+import { ProfileInterestTypes } from '@lens-protocol/api-bindings';
+import { success } from '@lens-protocol/shared-kernel';
+
+import { UseDeferredTask, useDeferredTask } from '../helpers/tasks';
+import { useProfileInterestsController } from './adapters/useProfileInterestsController';
+
+export { ProfileInterestTypes };
+
+export type AddProfileInterestsArgs = {
+  interests: ProfileInterestTypes[];
+};
+
+/**
+ * Add profile interests.
+ *
+ * You MUST be authenticated via {@link useLogin} to use this hook.
+ *
+ * @example
+ * ```tsx
+ * function ProfileInterests({ profile }: { profile: Profile }) {
+ *   const { execute: addInterests } = useAddProfileInterests();
+ *   const { execute: removeInterests } = useRemoveProfileInterests();
+ *
+ *   const handleClick = async (interest: ProfileInterestTypes) => {
+ *     const request = {
+ *       interests: [interest],
+ *     };
+ *
+ *     if (profile.interests.includes(interest)) {
+ *       await removeInterests(request);
+ *     } else {
+ *       await addInterests(request);
+ *     }
+ *   };
+ *
+ *   return <button onClick={() => handleClick(ProfileInterestTypes.Business)}>Business</button>;
+ * }
+ * ```
+ *
+ * @category Profiles
+ * @group Hooks
+ */
+export function useAddProfileInterests(): UseDeferredTask<void, never, AddProfileInterestsArgs> {
+  const { add } = useProfileInterestsController();
+
+  return useDeferredTask(async (request) => {
+    await add({
+      interests: request.interests,
+    });
+
+    return success();
+  });
+}
diff --git a/packages/react/src/profile/useRemoveProfileInterests.ts b/packages/react/src/profile/useRemoveProfileInterests.ts
new file mode 100644
index 000000000..5c23f8969
--- /dev/null
+++ b/packages/react/src/profile/useRemoveProfileInterests.ts
@@ -0,0 +1,57 @@
+import { ProfileInterestTypes } from '@lens-protocol/api-bindings';
+import { success } from '@lens-protocol/shared-kernel';
+
+import { UseDeferredTask, useDeferredTask } from '../helpers/tasks';
+import { useProfileInterestsController } from './adapters/useProfileInterestsController';
+
+export { ProfileInterestTypes };
+
+export type RemoveProfileInterestsArgs = {
+  interests: ProfileInterestTypes[];
+};
+
+/**
+ * Remove profile interests.
+ *
+ * You MUST be authenticated via {@link useLogin} to use this hook.
+ *
+ * @example
+ * ```tsx
+ * function ProfileInterests({ profile }: { profile: Profile }) {
+ *   const { execute: addInterests } = useAddProfileInterests();
+ *   const { execute: removeInterests } = useRemoveProfileInterests();
+ *
+ *   const handleClick = async (interest: ProfileInterestTypes) => {
+ *     const request = {
+ *       interests: [interest],
+ *     };
+ *
+ *     if (profile.interests.includes(interest)) {
+ *       await removeInterests(request);
+ *     } else {
+ *       await addInterests(request);
+ *     }
+ *   };
+ *
+ *   return <button onClick={() => handleClick(ProfileInterestTypes.Business)}>Business</button>;
+ * }
+ * ```
+ *
+ * @category Profiles
+ * @group Hooks
+ */
+export function useRemoveProfileInterests(): UseDeferredTask<
+  void,
+  never,
+  RemoveProfileInterestsArgs
+> {
+  const { remove } = useProfileInterestsController();
+
+  return useDeferredTask(async (request) => {
+    await remove({
+      interests: request.interests,
+    });
+
+    return success();
+  });
+}