HLA_B_13_02.txt

HLA_Allele	Significance test	Clinical Relevance	Method	Experimental methods	Reference	Armenia_combined_Regions_(n=100)	Australia_New_South_Wales_Caucasian_(n=134)	Australia_Yuendumu_Aborigine_(n=191)	Austria_(n=200)	Azores_Central_Islands_(n=59)	Azores_Oriental_Islands_(n=43)	Azores_Terceira_Island_(n=130)	Belgium_(n=99)	Brazil_Puyanawa_(n=150)	Brazil_Barra_Mansa_Rio_State_Black_(n=73)	Brazil_Barra_Mansa_Rio_State_Caucasian_(n=405)	Brazil_Belo_Horizonte_Caucasian_(n=95)	Brazil_Rio_de_Janeiro_Black_(n=68)	Brazil_Rio_de_Janeiro_Caucasian_(n=521)	Brazil_Rio_de_Janeiro_Parda_(n=170)	Brazil_Vale_do_Ribeira_Quilombos_(n=144)	Bulgaria_(n=55)	Cameroon_Baka_Pygmy_(n=10)	Cameroon_Bakola_Pygmy_(n=50)	Cameroon_Bamileke_(n=77)	Cameroon_Beti_(n=174)	Cameroon_Sawa_(n=13)	Cameroon_Yaounde_(n=92)	Cape_Verde_Northwestern_Islands_(n=62)	Cape_Verde_Southeastern_Islands_(n=62)	Central_African_Republic_Mbenzele_Pygmy_(n=36)	Chile_Santiago_Mixed_(n=70)	China_Beijing_(n=67)	China_Beijing_Shijiazhuang_Tianjian_Han_(n=618)	China_Canton_Han_(n=264)	China_Guangdong_Province_Meizhou_Han_(n=100)	China_Guangzhou_(n=102)	China_Han_HIV_negative_(n=72)	China_Henan_HIV_negative_(n=16)	China_Hubei_Han_(n=3732)	China_Inner_Mongolia_Region_(n=102)	China_Jiangsu_Han_(n=3238)	China_Jiangsu_Province_Han_(n=334)	China_North_Han_(n=105)	China_Qinghai_Province_Hui_(n=110)	China_Shanxi_HIV_negative_(n=22)	China_Sichuan_HIV_negative_(n=34)	China_South_Han_(n=284)	China_Tibet_Region_Tibetan_(n=158)	China_Uyghur_HIV_negative_(n=19)	China_Yunnan_Bulang_(n=116)	China_Yunnan_Hani_(n=150)	China_Yunnan_Province_Han_(n=101)	China_Zhejiang_Han_(n=1734)	Colombia_Bogotá_Cord_Blood_(n=1463)	Costa_Rica_African_-Caribbean_(G)_(n=102)	Costa_Rica_Amerindians_(G)_(n=125)	Costa_Rica_Central_Valley_Mestizo_(G)_(n=221)	Costa_Rica_Guanacaste_Mestizo_(G)_(n=110)	Croatia_(n=150)	Croatia_pop_4_(n=4000)	Cuba_Caucasian_(n=70)	Cuba_Mixed_Race_(n=42)	Czech_Republic_(n=106)	Czech_Republic_NMDR_(n=5099)	England_Blood_Donors_of_Mixed_Ethnicity_(n=519)	England_North_West_(n=298)	Finland_(n=91)	France_French_Bone_Marrow_Donor_Registry_(n=42623)	Gaza_(n=42)	Georgia_Svaneti_Region_Svan_(n=80)	Georgia_Tibilisi_(n=109)	Georgia_Tibilisi_Kurd_(n=31)	Germany_DKMS_-_Austria_minority_(n=1698)	Germany_DKMS_-_Bosnia_and_Herzegovina_minority_(n=1028)	Germany_DKMS_-_China_minority_(n=1282)	Germany_DKMS_-_Croatia_minority_(n=2057)	Germany_DKMS_-_France_minority_(n=1406)	Germany_DKMS_-_German_donors_(n=3456066)	Germany_DKMS_-_Greece_minority_(n=1894)	Germany_DKMS_-_Italy_minority_(n=1159)	Germany_DKMS_-_Netherlands_minority_(n=1374)	Germany_DKMS_-_Portugal_minority_(n=1176)	Germany_DKMS_-_Romania_minority_(n=1234)	Germany_DKMS_-_Spain_minority_(n=1107)	Germany_DKMS_-_Turkey_minority_(n=4856)	Germany_DKMS_-_United_Kingdom_minority_(n=1043)	Germany_pop_6_(n=8862)	Germany_pop_8_(n=39689)	Ghana_Accre_Asutuare_Akan_(n=429)	Greece_pop_6_(n=242)	Greece_pop_8_(n=83)	Guinea_Bissau_(n=65)	Hong_Kong_Chinese_(n=569)	Hong_Kong_Chinese_BMDR_(n=7595)	Hong_Kong_Chinese_cord_blood_registry_(n=3892)	Hong_Kong_Chinese_HKBMDR_HLA_11_loci_(n=5266)	India_Andhra_Pradesh_Golla_(n=111)	India_Andhra_Pradesh_Telugu_Speaking_(n=186)	India_Delhi_pop_2_(n=90)	India_Karnataka_Kannada_Speaking_(n=174)	India_Kerala_Malayalam_speaking_(n=356)	India_Khandesh_Region_Pawra_(n=50)	India_Mumbai_Maratha_(n=91)	India_Tamil_Nadu_(n=2492)
B*13:02	P = 0.036	Associated with vaccinia-induced antibodies	Experimentally proven	Neutralizing Antibody Assay, IFN-γ Elispot, Cytokine Measurements, HLA Genotyping	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096794/	0.035	0.008	0	0.048	0.027	0.013	0.008	0.015	0.02			0.005				0	0.027	0		0.019	0.023	0	0.027	0	0			0.076	0.055	0.021	0.015	0.015	0.094	0.094	0.044		0.116	0.101	0.038	0.059	0.114	0.015	0.018	0.003	0.026	0.004	0.003	0.015		0.00923					0.02	0.038	0.029	0.012	0.066	0.047		0.007	0.017	0.02	0.024	0.063	0.056	0.034	0.038	0.049	0.067	0.037	0.022	0.034	0.031	0.038	0.023	0.023	0.036	0.019	0.039	0.029	0.031	0.035	0.008	0.033	0.03	0.023	0.019	0.017	0.017		0.014		0.022			0	0.043	0.013
B*13:02:01															0.021	0.00988		0.015	0.014	0.024																																		0.047		0.005	0.012	0.005	0.009							0.023																															0.017		0.016		0.02	0.008			
B*13:02:02																																									0.034																																																																
Total Frequency						0.035	0.008	0	0.048	0.027	0.013	0.008	0.015	0.02	0.021	0.01	0.005	0.015	0.014	0.024	0	0.027	0	0	0.019	0.023	0	0.027	0	0	0	0	0.076	0.055	0.021	0.015	0.015	0.094	0.094	0.044	0.034	0.116	0.101	0.038	0.059	0.114	0.015	0.018	0.003	0.026	0.004	0.003	0.015	0.047	0.009	0.005	0.012	0.005	0.009	0.02	0.038	0.029	0.012	0.066	0.047	0.023	0.007	0.017	0.02	0.024	0.063	0.056	0.034	0.038	0.049	0.067	0.037	0.022	0.034	0.031	0.038	0.023	0.023	0.036	0.019	0.039	0.029	0.031	0.035	0.008	0.033	0.03	0.023	0.019	0.017	0.017	0.017	0.014	0.016	0.022	0.02	0.008	0	0.043	0.013