diff --git a/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_creation/custom_saved_query_rule.cy.ts b/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_creation/custom_saved_query_rule.cy.ts
index 913218797fd76..48f2bd4002f3b 100644
--- a/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_creation/custom_saved_query_rule.cy.ts
+++ b/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_creation/custom_saved_query_rule.cy.ts
@@ -132,22 +132,27 @@ describe('Saved query rules', { tags: ['@ess', '@serverless'] }, () => {
           cy.get(TOASTER).should('contain', FAILED_TO_LOAD_ERROR);
         });
 
-        it('Allows to update saved_query rule with non-existent query', () => {
-          cy.get(LOAD_QUERY_DYNAMICALLY_CHECKBOX).should('exist');
-
-          cy.intercept('PUT', '/api/detection_engine/rules').as('editedRule');
-          saveEditedRule();
-
-          cy.wait('@editedRule').then(({ response }) => {
-            // updated rule type shouldn't change
-            cy.wrap(response?.body.type).should('equal', 'saved_query');
-          });
-
-          cy.get(DEFINE_RULE_PANEL_PROGRESS).should('not.exist');
-
-          assertDetailsNotExist(SAVED_QUERY_NAME_DETAILS);
-          assertDetailsNotExist(SAVED_QUERY_DETAILS);
-        });
+        // https://github.com/elastic/kibana/issues/187623
+        it(
+          'Allows to update saved_query rule with non-existent query',
+          { tags: ['@skipInServerlessMKI'] },
+          () => {
+            cy.get(LOAD_QUERY_DYNAMICALLY_CHECKBOX).should('exist');
+
+            cy.intercept('PUT', '/api/detection_engine/rules').as('editedRule');
+            saveEditedRule();
+
+            cy.wait('@editedRule').then(({ response }) => {
+              // updated rule type shouldn't change
+              cy.wrap(response?.body.type).should('equal', 'saved_query');
+            });
+
+            cy.get(DEFINE_RULE_PANEL_PROGRESS).should('not.exist');
+
+            assertDetailsNotExist(SAVED_QUERY_NAME_DETAILS);
+            assertDetailsNotExist(SAVED_QUERY_DETAILS);
+          }
+        );
       });
     });
 
diff --git a/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_creation/machine_learning_rule.cy.ts b/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_creation/machine_learning_rule.cy.ts
index 57c0c39f8a8f9..50ca504e7a125 100644
--- a/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_creation/machine_learning_rule.cy.ts
+++ b/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_creation/machine_learning_rule.cy.ts
@@ -54,7 +54,8 @@ import { CREATE_RULE_URL } from '../../../../urls/navigation';
 import { forceStopAndCloseJob } from '../../../../support/machine_learning';
 import { deleteAlertsAndRules } from '../../../../tasks/api_calls/common';
 
-describe('Machine Learning rules', { tags: ['@ess', '@serverless'] }, () => {
+// https://github.com/elastic/kibana/issues/187622
+describe('Machine Learning rules', { tags: ['@ess', '@serverless, @skipInServerlessMKI'] }, () => {
   const expectedUrls = (getMachineLearningRule().references ?? []).join('');
   const expectedFalsePositives = (getMachineLearningRule().false_positives ?? []).join('');
   const expectedTags = (getMachineLearningRule().tags ?? []).join('');
diff --git a/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_edit/indicator_match_rule.cy.ts b/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_edit/indicator_match_rule.cy.ts
index 7d5a21b6f7c82..378bcedf835f6 100644
--- a/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_edit/indicator_match_rule.cy.ts
+++ b/x-pack/test/security_solution_cypress/cypress/e2e/detection_response/detection_engine/rule_edit/indicator_match_rule.cy.ts
@@ -56,7 +56,9 @@ describe(
       login();
       deleteAlertsAndRules();
     });
-    describe('without suppression', () => {
+
+    // https://github.com/elastic/kibana/issues/187621
+    describe('without suppression', { tags: ['@skipInServerlessMKI'] }, () => {
       beforeEach(() => {
         createRule(rule);
       });