-
Notifications
You must be signed in to change notification settings - Fork 0
/
old-publications.html
602 lines (559 loc) · 33.2 KB
/
old-publications.html
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
<!DOCTYPE HTML>
<!--
Spectral by HTML5 UP
html5up.net | @ajlkn
Free for personal and commercial use under the CCA 3.0 license (html5up.net/license)
-->
<html>
<head>
<title>The Waudby Group | Publications</title>
<meta charset="utf-8" />
<meta name="viewport" content="width=device-width, initial-scale=1, user-scalable=no" />
<link rel="stylesheet" href="assets/css/main.css" />
<link rel="stylesheet" href="https://cdn.jsdelivr.net/gh/jpswalsh/academicons@1/css/academicons.min.css">
<noscript><link rel="stylesheet" href="assets/css/noscript.css" /></noscript>
</head>
<body class="is-preload">
<!-- Page Wrapper -->
<div id="page-wrapper">
<!-- Header -->
<header id="header">
<h1><a href="index.html">The Waudby Group</a></h1>
<nav id="nav">
<ul>
<li class="special">
<a href="#menu" class="menuToggle"><span>Menu</span></a>
<div id="menu">
<ul>
<li><a href="index.html"><i class="icon solid fa-home"></i> Home</a></li>
<li><a href="index.html#news"><i class="icon solid fa-newspaper"></i> News</a></li>
<li><a href="research.html"><i class="icon solid fa-flask"></i> Research</a></li>
<li><a href="teaching.html"><i class="icon solid fa-person-chalkboard"></i> Teaching</a></li>
<li><a href="publications.html"><i class="icon solid fa-book-open"></i> Publications</a></li>
<li><a href="software.html"><i class="icon solid fa-code"></i> Software</a></li>
<li><a href="facilities.html"><i class="icon solid fa-magnet"></i> Facilities</a></li>
<li><a href="team.html"><i class="icon solid fa-people-group"></i> Team</a></li>
<li><a href="contact.html"><i class="icon solid fa-envelope"></i> Contact</a></li>
</ul>
</div>
</li>
</ul>
</nav>
</header>
<!-- Main -->
<article id="main">
<header>
<h2>Publications</h2>
<ul class="actions special">
<li><a href="https://orcid.org/0000-0001-7810-3753" class="button primary">ORCID</a></li>
<li><a href="https://scholar.google.com/citations?hl=en&user=e2RJhjcAAAAJ" class="button">Google Scholar</a></li>
</ul>
</header>
<!-- <section id="one" class="wrapper alt style5">
<section class="spotlight">
<div class="image"><img src="images/pic01.jpg" alt="" /></div><div class="content">
<h2>Distinct dissociation rates of murine and human norovirus P-domain dimers suggest a role of dimer stability in virus-host interactions.</h2>
<p>
Creutznacher R, Maass T, Dülfer J, Feldmann C, Hartmann V, Lane MS, Knickmann J, Westermann LT, Thiede L, Smith TJ, Uetrecht C, Mallagaray A, Waudby CA, Taube S, Peters T.
<i>Commun Biol</i> <b>13</b> 1214-1220 (2021).
<a href="https://www.nature.com/articles/s42003-022-03497-4.pdf"><i class="icon solid fa-file-pdf"></i></a>
</p>
</div>
</section>
</section> -->
<section class="wrapper style5">
<div class="inner">
<h2>Publication list</h2>
<ul class="actions">
<li><a href="#articles" class="button">Articles</a></li>
<li><a href="#reviews" class="button">Reviews</a></li>
<li><a href="#talks" class="button">Talks</a></li>
</ul>
<!--
<a href=""><i class="icon solid fa-file-pdf"></i></a>
<a href=""><i class="ai ai-doi"></i></a>
<a href=""><i class="icon solid fa-link"></i></a>
-->
<h3 id="articles">Articles</h3>
<h4>Preprints</h4>
<ol>
<li>
Chan SHS, Waudby CA, Christodoulou J.
<i>ChemRxiv</i>.
NMR snapshots of nascent chains emerging from the ribosome during biosynthesis.
<a href="https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/621cfe7157a9d2e3156e38c3/original/nmr-snapshots-of-nascent-chains-emerging-from-the-ribosome-during-biosynthesis.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Waudby CA, Christodoulou J.
<i>ChemRxiv</i>.
NMR Resolution Enhancement and Homonuclear Decoupling Using Non-Uniform Weighted Sampling.
<a href="https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/60c748ff0f50db1b94396842/original/nmr-resolution-enhancement-and-homonuclear-decoupling-using-non-uniform-weighted-sampling.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2022</h4>
<ol>
<li>
Waudby CA, Alvarez-Teijeiro S, Ruiz EJ, Suppinger S, Pinotsis N, Brown PR, Behrens A, Christodoulou J, Mylona A.
<i>Nat Commun</i> <b>13</b> 6133 (2022).
An intrinsic temporal order of c-JUN N-terminal phosphorylation regulates its activity by orchestrating co-factor recruitment.
<a href="https://www.nature.com/articles/s41467-022-33866-w"><i class="icon solid fa-link"></i></a>
<a href="https://www.nature.com/articles/s41467-022-33866-w.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Pavlović RZ, Zhiquan L, Finnegan TJ, Waudby CA, Wang X, VWL, Zhu X, Wong CM, Hamby T, Moore CE, Hoefer N, McComb DW, Sevov CS, Badjic JC.
<i>Angew Chem Int Ed</i> (2022).
Closed Aromatic Tubes - Capsularenes.
<a href="https://onlinelibrary.wiley.com/doi/10.1002/anie.202211304"><i class="icon solid fa-link"></i></a>
<a href="https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202211304"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Chan SHS, Włodarski T, Streit JO, Cassaignau AME, Woodburn LF, Ahn M, von Sass GJF, Waudby CA, Budisa N, Cabrita LD, Christodoulou J.
<i>Nature Chemistry</i> (2022).
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein.
<a href="https://www.nature.com/articles/s41557-022-01004-0"><i class="icon solid fa-link"></i></a>
<a href="https://www.nature.com/articles/s41557-022-01004-0.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Ahn M, Włodarski T, Mitropoulou A, Chan SHS, Sidhu H, Plessa E, Becker TA, Budisa N, Waudby CA, Beckmann R, Cassaignau AME, Cabrita LD, Christodoulou J.
<i>Nat Commun</i> <b>13</b> 4243 (2022).
Modulating co-translational protein folding by rational design and ribosome engineering.
<a href="https://www.nature.com/articles/s41467-022-31906-z"><i class="icon solid fa-link"></i></a>
<a href="https://www.nature.com/articles/s41467-022-31906-z.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Creutznacher R, Maass T, Dülfer J, Feldmann C, Hartmann V, Lane MS, Knickmann J, Westermann LT, Thiede L, Smith TJ, Uetrecht C, Mallagaray A, Waudby CA, Taube S, Peters T.
<i>Commun Biol</i> <b>5</b> 563 (2022).
Distinct dissociation rates of murine and human norovirus P-domain dimers suggest a role of dimer stability in virus-host interactions.
<a href="https://www.nature.com/articles/s42003-022-03497-4"><i class="icon solid fa-link"></i></a>
<a href="https://www.nature.com/articles/s42003-022-03497-4.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2021</h4>
<ol>
<li>
Deckert A, Cassaignau AME, Wang X, Włodarski T, Chan SHS, Waudby CA, Kirkpatrick J, Vendruscolo M, Cabrita LD, Christodoulou J.
<i>Proc Natl Acad Sci U S A</i> <b>118</b> e2103015118 (2021).
Common sequence motifs of nascent chains engage the ribosome surface and trigger factor.
<a href="https://doi.org/10.1073/pnas.2103015118"><i class="ai ai-doi"></i></a>
<a href="https://www.pnas.org/doi/pdf/10.1073/pnas.2103015118"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Plessa E, Chu LP, Chan SHS, Thomas OL, Cassaignau AME, Waudby CA, Christodoulou J, Cabrita LD.
Nat Commun 12 6447 (2021).
Nascent chains can form co-translational folding intermediates that promote post-translational folding outcomes in a disease-causing protein.
<a href="https://doi.org/10.1038/s41467-021-26531-1"><i class="ai ai-doi"></i></a>
<a href="https://www.nature.com/articles/s41467-021-26531-1.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Cassaignau AME, Włodarski T, Chan SHS, Woodburn LF, Bukvin IV, Streit JO, Cabrita LD, Waudby CA*, Christodoulou J*.
<i>Nature Chemistry</i> <b>13</b> 1214-1220 (2021).
Interactions between nascent proteins and the ribosome surface inhibit co-translational folding.
<a href="https://www.nature.com/articles/s41557-021-00796-x.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Burridge C*, Waudby CA*, Wlodarski T, Cassaignau AME, Cabrita LD, Christodoulou J.
<i>Chem Sci</i> <b>12</b> 13120-13126 (2021).
Nascent chain dynamics and ribosome interactions within folded ribosome-nascent chain complexes observed by NMR spectroscopy.
<a href="https://doi.org/10.1039/d1sc04313g"><i class="ai ai-doi"></i></a>
<a href="https://pubs.rsc.org/en/content/articlepdf/2021/sc/d1sc04313g"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Badjic JD, Pavlović RZ, Lalisse RF, Hansen AL, Waudby CA, Zhiquan L, Guney M, Wang X, Hadad CM.
<i>Angew Chem Int Ed</i> <b>60</b> 19942-19948 (2021).
From Selection to Instruction and Back: Competing Conformational Selection and Induced Fit Pathways in Abiotic Hosts.
<a href="https://doi.org/10.1002/anie.202107091"><i class="ai ai-doi"></i></a>
<a href="https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202107091"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Waudby CA, Christodoulou J.
<i>Magn Reson</i> <b>2</b> 777-793 (2021).
Analysis of conformational exchange processes using methyl-TROSY-based Hahn echo measurements of quadruple-quantum relaxation.
<a href="https://mr.copernicus.org/articles/2/777/2021/"><i class="icon solid fa-link"></i></a>
<a href="https://mr.copernicus.org/articles/2/777/2021/mr-2-777-2021.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Waudby CA, Burridge C, Christodoulou J.
<i>J Magn Reson</i> <b>326</b> 106973 (2021).
Optimal design of adaptively sampled NMR experiments for measurement of methyl group dynamics with application to a ribosome-nascent chain complex.
<a href="https://doi.org/10.1016/j.jmr.2021.106937"><i class="ai ai-doi"></i></a>
</li>
</ol>
<h4>2020</h4>
<ol>
<li>
Jagger AM*, Waudby CA*, Irving JA, Christodoulou J, Lomas DA.
<i>Nature Commun</i> <b>11</b> 6371 (2020).
High-resolution ex vivo NMR spectroscopy of human Z ɑ<sub>1</sub>-antitrypsin.
<a href="https://www.nature.com/articles/s41467-020-20147-7.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Waudby CA, Christodoulou J.
<i>Methods Mol Biol</i> <b>2141</b> 477-504 (2020).
NMR Lineshape Analysis of Intrinsically Disordered Protein Interactions.
<a href="https://link.springer.com/protocol/10.1007%2F978-1-0716-0524-0_24"><i class="icon solid fa-link"></i></a>
</li>
<li>
Stadmiller S, Aguilar J, Waudby CA, Pielak G.
<i>Biophys J</i> <b>118</b> 2537-2548 (2020).
Rapid quantification of protein-ligand binding via <sup>19</sup>F NMR lineshape analysis.
<a href="https://www.cell.com/biophysj/fulltext/S0006-3495(20)30304-0"><i class="icon solid fa-link"></i></a>
</li>
<li>
Ben Bdira F, Waudby CA, Volkov AN, Schröder SP, Ab E, Codée JDC, Overkleeft HS, Aerts JMFG, van Ingen H, Ubbink M.
<i>Angew Chem Int Ed</i> <b>59</b> 20508-20514 (2020).
Dynamics of Ligand Binding to a Rigid Glycosylase.
<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202003236"><i class="icon solid fa-link"></i></a>
</li>
<li>
Waudby CA, Ouvry M, Davis B, Christodoulou J.
<i>J Biomol NMR</i> <b>74</b> 95-109 (2020).
Two-dimensional NMR lineshape analysis of single, multiple, zero and double quantum correlation experiments.
<a href="https://link.springer.com/article/10.1007/s10858-019-00297-7"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2019</h4>
<ol>
<li>
Wang X, Kirkpatrick JP, Launay HMM, De Simone A, Häussinger D, Dobson CM, Vendruscolo M, Cabrita LD, Waudby CA*, Christodoulou J*.
<i>Scientific Reports</i> <b>9</b> 13528 (2019).
Probing the dynamic stalk region of the ribosome using solution NMR.
<a href="https://www.nature.com/articles/s41598-019-49190-1.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Corazza A, Verona G, Waudby CA, Mangione P, Bingham R, Uings I, Canetti D, Nocerino P, Taylor GW, Pepys MB, Christodoulou J & Bellotti V.
<i>J Med Chem</i> <b>62</b> 8274-8283 (2019).
Binding of Monovalent and Bivalent Ligands by Transthyretin Causes Different Short- and Long-Distance Conformational Changes.
<a href="https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01037"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Waudby CA, Frenkiel T, Christodoulou J.
<i>Angew Chemie Int Ed</i> <b>131</b> 8876-8880 (2019).
Cross-peaks in simple two-dimensional NMR experiments from chemical exchange of transverse magnetization.
<a href="https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201903245"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2018</h4>
<ol>
<li>
Waudby CA, Karyadi M, Wlodarski T, Cassaignau A, Chan S, Schmidt-Engler J, Wentink A, Camilloni C, Vendruscolo M, Cabrita LD, Christodoulou J.
<i>Proc Natl Acad Sci U S A</i> <b>115</b> 9744-9749 (2018).
Systematic mapping of energy landscapes identifies a kinetic intermediate associated with the co-translational folding of a filamin domain.
<a href="https://www.pnas.org/content/pnas/115/39/9744.full.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2017</h4>
<ol>
<li>
Ahn M, Waudby CA, Bernardo-Gancedo A, De Genst E, Dhulesia A, Salvatella X, Christodoulou C, Dobson CM, Kumita JM.
<i>Sci Rep</i> <b>7</b> 15018 (2017).
Application of lysine-specific labeling to detect transient interactions present during human lysozyme amyloid fibril formation.
<a href="https://www.nature.com/articles/s41598-017-14739-5.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2016</h4>
<ol>
<li>
Cassaignau AM, Launay HM, Karyadi ME, Wang X, Waudby CA, Deckert A, Robertson AL, Christodoulou J, Cabrita LD.
<i>Nat Protoc</i> 11 1492-1507 (2016).
A strategy for co-translational folding studies of ribosome-bound nascent chain complexes using NMR spectroscopy.
<a href="https://www.nature.com/articles/nprot.2016.101.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Waudby CA, Ramos A, Cabrita LD, Christodoulou J.
<i>Sci Rep</i> <b>6</b> 24826 (2016).
Two-Dimensional NMR Lineshape Analysis.
<a href="https://www.nature.com/articles/srep24826.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Deckert A, Waudby CA, Wlodarski T, Wentink AS, Wang X, Kirkpatrick JP, Paton JF, Camilloni C, Kukic P, Dobson CM, Vendruscolo M, Cabrita LD, Christodoulou J.
<i>Proc Natl Acad Sci U S A</i> <b>113</b> 5012-7 (2016).
Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor.
<a href="https://www.pnas.org/content/pnas/113/18/5012.full.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Cabrita LD, Cassaignau AM, Launay HM, Waudby CA, Wlodarski T, Camilloni C, Karyadi ME, Robertson AL, Wang X, Wentink AS, Goodsell LS, Woolhead CA, Vendruscolo M, Dobson CM, Christodoulou J.
<i>Nat Struct Mol Biol</i> <b>23</b> 278-85 (2016).
A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.
<a href="http://www-vendruscolo.ch.cam.ac.uk/cabrita2016nsmb.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Valleix S, Verona G, Jourde-Chiche N, Nédelec B, Mangione PP, Bridoux F, Mangé A, Dogan A, Goujon JM, Lhomme M, Dauteuille C, Chabert M, Porcari R, Waudby CA, Relini A, Talmud PJ, Kovrov O, Olivecrona G, Stoppini M, Christodoulou J, Hawkins PN, Grateau G, Delpech M, Kontush A, Gillmore JD, Kalopissis AD, Bellotti V.
<i>Nat Commun</i> <b>7</b> 10353 (2016).
D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile.
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735822/pdf/ncomms10353.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2015</h4>
<ol>
<li>
Chan SH*, Waudby CA*, Cassaignau AM, Cabrita LD, Christodoulou J.
<i>J Biomol NMR</i> <b>63</b> 151-63 (2015).
Increasing the sensitivity of NMR diffusion measurements by paramagnetic longitudinal relaxation enhancement, with application to ribosome-nascent chain complexes.
<a href="https://link.springer.com/content/pdf/10.1007%2Fs10858-015-9968-x.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Porcari R, Proukakis C, Waudby CA, Bolognesi B, Mangione PP, Paton JF, Mullin S, Cabrita LD, Penco A, Relini A, Verona G, Vendruscolo M, Stoppini M, Tartaglia GG, Camilloni C, Christodoulou J, Schapira AH, Bellotti V.
<i>J Biol Chem</i> <b>290</b> 2395-404 (2015).
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.
<a href="http://www.jbc.org/content/290/4/2395.full.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2013</h4>
<ol>
<li>
Waudby CA, Camilloni C, Fitzpatrick AWP, Dobson CM, Vendruscolo M, Christodoulou J.
<i>PLoS ONE</i> <b>8</b> e72286 (2013).
In-cell NMR spectroscopy reveals the secondary structure of a disordered conformation of α-synuclein within the cell.
<a href="https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0072286&type=printable"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Daturpalli S, Wang S, Buell A, Waudby CA, Meehan S, Jackson SE.
<i>J Mol Biol</i> <b>425</b> 4614-4628 (2013).
Hsp90 Inhibits α-Synuclein Aggregation by Interacting with Soluble Oligomers.
<a href="https://www.sciencedirect.com/science/article/pii/S0022283613005093"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Fitzpatrick AWP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Vajaj VS, Jaroniec CP, Wang L, Ladizhandsky V, Muller S, MacPhee CE, Waudby CA, Mott H, de Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova E, Griffin RG, Dobson CM.
<i>Proc Natl Acad Sci U S A</i> <b>110</b> 5468-5473 (2013).
Atomic-resolution structure of a cross-β amyloid fibril.
<a href="https://www.pnas.org/content/pnas/110/14/5468.full.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2012</h4>
<ol>
<li>
Waudby CA, Mantle MD, Cabrita LD, Gladden LF, Dobson CM, Christodoulou J.
<i>J Am Chem Soc</i> <b>134</b> 11312-11315 (2012).
Rapid distinction of intracellular and extracellular proteins using NMR diffusion measurements.
<a href="https://pubs.acs.org/doi/pdf/10.1021/ja304912c"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Waudby CA (corresponding), Christodoulou J.
<i>J Magn Reson</i> <b>219</b> 46-52 (2012).
An analysis of NMR sensitivity enhancements obtained using non-uniform weighted sampling, and the application to protein NMR.
<a href="https://www.sciencedirect.com/science/article/pii/S1090780712001711"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Nyon MP, Lévy GR, Segu L, Cabrita LD, Kirkpatrick J, Roussel BD, Patschull AOM, Barrett TE, Ekeowa UI, Kerr R, Waudby CA, Kalsheker N, Hill M, Thalassinos K, Christodoulou J, Gooptu B, Lomas DA.
<i>Structure</i> <b>20</b> 504-512 (2012).
Structural dynamics associated with intermediate formation in an archetypal conformational disease.
<a href="https://www.sciencedirect.com/science/article/pii/S0969212612000202"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2011</h4>
<ol>
<li>
Shammas SL, Waudby CA, Wang S, Buell AK, Ecroyd H, Welland ME, Carver JA, Dobson CM, Meehan S.
<i>Biophys J</i> <b>101</b> 1681-9 (2011).
Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation.
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183811/pdf/main.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Fitzpatrick A, Knowles TPJ, Waudby CA, Vendruscolo M, Dobson CM.
<i>PLoS Comp Biol</i> <b>7</b>, e1002169 (2011).
Inversion of the Balance between Hydrophobic and Hydrogen Bonding Interactions in Protein Folding and Aggregation.
<a href="https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002169&type=printable"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Cabrita LD*, Waudby CA*, Dobson CM, Christodoulou J.
<i>Methods Mol Biol</i> <b>752</b>, 97-120 (2011).
Solution-state nuclear magnetic resonance spectroscopy and protein folding.
<a href="https://link.springer.com/protocol/10.1007/978-1-60327-223-0_7"><i class="icon solid fa-link"></i></a>
</li>
<li>
Baldwin AJ, Knowles TPJ, Tartaglia G, Fitzpatrick A, Devlin G, Shammas S, Waudby CA, Mossuto MF, Gras SL, Christodoulou J, Anthony-Cahill SJ, Barker PD, Dobson CM.
<i>J Am Chem Soc</i> <b>133</b>, 14160-3 (2011).
Metastability of native proteins and the phenomenon of amyloid formation.
<a href="https://pubs.acs.org/doi/pdf/10.1021/ja2017703"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Waudby CA, Christodoulou J.
<i>J Magn Reson</i> <b>211</b>, 67-73 (2011).
GPU accelerated Monte Carlo simulation of pulsed-field gradient NMR experiments.
<a href="https://www.sciencedirect.com/science/article/pii/S1090780711001376"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Roodveldt C, Labrador-Garrido A, Gonzalez-Rey E, Fernandez-Monrtesinos R, Caro M, Lachaud CC, Waudby CA, Delgado M, Dobson CM, Pozo D.
<i>PLoS ONE</i> <b>5</b>, e13481 (2011).
Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants.
<a href="http://discovery.ucl.ac.uk/339613/1/339613.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
de-Genst EJJ, Guilliams T, Wellens J, O'Day E, Waudby CA, Meehan S, Dumoulin M, Hsu STD, Cremades N, Pardon E, Steyaert J, Wyns L, Christodoulou J, Dobson CM.
<i>J Mol Biol</i> <b>402</b>, 326-343 (2011).
Structure and properties of a complex of α-synuclein and a single domain camelid antibody.
<a href="https://www.sciencedirect.com/science/article/pii/S0022283610007424"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2010</h4>
<ol>
<li>
Carnall JM, Waudby CA, Belenguer AM, Stuart MC, Peyralans JJ & Otto S.
<i>Science</i> <b>327</b>, 1502-1506 (2010).
Mechanosensitive self-replication driven by self-organization.
<a href="https://science.sciencemag.org/content/327/5972/1502.full.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Waudby CA, Knowles TPJ, Devlin GL, Skepper JN, Ecroyd H, Carver JA, Welland ME, Christodoulou J, Dobson CM, Meehan S.
<i>Biophys J</i> <b>98</b>, 843-851 (2010).
The interaction of αB-crystallin with mature α-synuclein amyloid fibrils inhibits their elongation.
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830463/pdf/main.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2009</h4>
<ol>
<li>
Knowles TPJ, Waudby CA, Devlin GL, Cohen SIA, Aguzzi A, Vendruscolo M, Terentjev EM, Welland ME & Dobson CM.
<i>Science</i> <b>326</b>, 1533-1537 (2009).
An analytical solution to the kinetics of breakable filament assembly.
<a href="https://science.sciencemag.org/content/326/5959/1533.full.pdf"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Lendel C, Bertoncini CW, Cremades N, Waudby CA, Vendruscolo M, Dobson CM, Schenk D, Christodoulou J & Toth G.
<i>Biochemistry</i> <b>48</b>, 8322-8334 (2009).
On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and Lacmoid.
<a href="https://pubs.acs.org/doi/pdf/10.1021/bi901285x"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Büll AK, Tartaglia GG, Birkett NR, Waudby CA, Vendruscolo M, Salvatella X, Welland ME, Dobson CM & Knowles TPJ.
<i>ChemBioChem</i> <b>10</b>, 1309-1312 (2009).
Position-dependent electrostatic protection against protein aggregation.
<a href="https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.200900144"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2004</h4>
<ol>
<li>
Townsend JA, Adams SE, Waudby CA, de Souza VK, Goodman JM & Murray-Rust P.
<i>Org Biomol Chem</i> <b>2</b>, 3294-3300 (2004).
Chemical documents: machine understanding and automated information extraction.
<a href="https://pubs.rsc.org/en/content/articlepdf/2004/ob/b411033a"><i class="icon solid fa-file-pdf"></i></a>
</li>
<li>
Adams SE, Goodman JM, Kidd RJ, McNaught AD, Murray-Rust P, Norton FR, Townsend JA & Waudby CA.
<i>Org Biomol Chem</i> <b>2</b>, 3067-3070 (2004).
Experimental data checker: better information for organic chemists.
<a href="https://pubs.rsc.org/en/content/articlepdf/2004/ob/b411699m"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h3 id="reviews">Reviews</h3>
<h4>2022</h4>
<ol>
<li>
Waudby CA*, Burridge C*, Cabrita LD, Christodoulou J.
<i>Curr Opin Struct Biol</i> <b>74</b> 102357 (2022).
Thermodynamics of co-translational folding and ribosome-nascent chain interactions.
<a href="https://www.sciencedirect.com/science/article/pii/S0959440X22000367/pdfft?isDTMRedir=true"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h4>2019</h4>
<ol>
<li>
Waudby CA, Dobson CM, Christodoulou J.
<i>Trends Biochem Sci</i> (2019).
The regulation of protein folding on the ribosome.
<a href="https://doi.org/10.1016/j.tibs.2019.06.008"><i class="ai ai-doi"></i></a>
</li>
</ol>
<h4>2013</h4>
<ol>
<li>
Waudby CA, Launey H, Cabrita LD, Christodoulou J.
<i>Prog Nucl Magn Reson Spectrosc</i> <b>74</b> 57-75 (2013).
Protein folding on the ribosome studied using NMR spectroscopy.
<a href="https://www.sciencedirect.com/science/article/pii/S0079656513000654"><i class="icon solid fa-file-pdf"></i></a>
</li>
</ol>
<h3 id="bookreviews">Book Reviews</h3>
<ol>
<li>
Waudby CA, Christodoulou J.
<i>ChemBioChem</i> (2013).
NMR of Biomolecules: Towards Mechanistic Systems Biology.
<a href="https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.201300209"><i class="ai ai-doi"></i></a>
</li>
</ol>
<h3 id="talks">Selected talks</h3>
<ul>
<li>
Advanced Isotopic Labelling Methods (Grenoble, September 2022).
NMR without labelling: High-resolution <i>ex vivo</i> spectroscopy of patient-derived, disease-associated α<sub>1</sub>-antitrypsin variants.
</li>
<li>
Global NMR Twitter Conference (Aug 2022).
NMRTools.jl: a simple, open source interface for NMR data in Julia.
<a href="https://twitter.com/chris_waudby/status/1554731293455183874?s=20&t=0g8ZqE0r816f1HjNoZQkWg"><i class="icon brands fa-twitter"></i></a>
</li>
<li>
EUROMAR (Utrecht, Jul 2022).
Analysis of sidechain dynamics using slowly-relaxing methyl quadruple-quantum coherences.
</li>
<li>
CCPN (Ambleside, Aug 2021).
Probing chemical exchange using multiple-quantum coherences.
<a href="https://youtu.be/xvgz2XRgUq4"><i class="icon brands fa-youtube"></i></a>
</li>
<li>
Global NMR Discussion Meetings (June 2021).
Two-dimensional lineshape analysis of biomolecular interactions.
<a href="https://www.youtube.com/watch?v=-06ewqtUJzM"><i class="icon brands fa-youtube"></i></a>
</li>
<li>
ELRIG (Feb 2021).
New developments in the analysis of molecular interactions using NMR spectroscopy.
</li>
<li>
ICMRBS ECR Webinar (Sep 2020).
High-resolution ex vivo NMR spectroscopy of human Z ɑ<sub>1</sub>-antitrypsin.
<a href="https://www.youtube.com/watch?v=9X4aLPQbn18&t=1597s"><i class="icon brands fa-youtube"></i></a>
</li>
<li>
ENC (Baltimore, Mar 2020).
Dissecting interactions of nascent chains with the ribosome surface using NMR spectroscopy.
</li>
<li>
British Crystallographic Association Spring Meeting (Nottingham, Apr 2019).
Dissecting the interactions of nascent chains with the ribosome surface: an intrinsic holdase activity of the ribosome surface?
</li>
<li>
London NMR Forum (London, Jan 2019).
New developments in two-dimensional NMR lineshape analysis.
</li>
<li>
ICMRBS (Dublin, Aug 2018).
High-resolution 2D NMR spectroscopy of patient-derived glycoproteins at natural isotopic abundance.
</li>
<li>
EUROMAR (Nantes, Jul 2018).
Quantifying ribosome-nascent chain interactions and intracellular quinary structure using adaptively sampled measurements of cross-correlated relaxation in methyl spin systems.
</li>
<li>
British/Belgian Biophysical Societies (Brussells, Feb 2018).
Mapping the free energy landscapes for co-translational folding of a filamin domain.
</li>
</ul>
</div>
</section>
</article>
<!-- Footer -->
<footer id="footer">
<ul class="icons">
<li><a href="https://www.twitter.com/chris_waudby" class="icon brands fa-twitter"><span class="label">Twitter</span></a></li>
<li><a href="contact.html" class="icon solid fa-envelope"><span class="label">Contact</span></a></li>
</ul>
<ul class="copyright">
<li>© Waudby Group 2022</li><li>Design: <a href="http://html5up.net">HTML5 UP</a></li>
</ul>
</footer>
</div>
<!-- Scripts -->
<script src="assets/js/jquery.min.js"></script>
<script src="assets/js/jquery.scrollex.min.js"></script>
<script src="assets/js/jquery.scrolly.min.js"></script>
<script src="assets/js/browser.min.js"></script>
<script src="assets/js/breakpoints.min.js"></script>
<script src="assets/js/util.js"></script>
<script src="assets/js/main.js"></script>
<script src="https://kit.fontawesome.com/2ea35fb7c9.js" crossorigin="anonymous"></script>
</body>
</html>