diff --git a/packages/nx/src/plugins/js/utils/register.ts b/packages/nx/src/plugins/js/utils/register.ts
index f60d7bbde2bf1..60f57e67f86c5 100644
--- a/packages/nx/src/plugins/js/utils/register.ts
+++ b/packages/nx/src/plugins/js/utils/register.ts
@@ -73,7 +73,9 @@ export function getTsNodeTranspiler(
     warnTsNodeUsage();
   }
 
-  return () => {};
+  return () => {
+    service.enabled(false);
+  };
 }
 
 export function getTranspiler(compilerOptions: CompilerOptions) {
diff --git a/packages/nx/src/project-graph/project-graph.ts b/packages/nx/src/project-graph/project-graph.ts
index a6b2c25a2cb30..f8dcd65a00370 100644
--- a/packages/nx/src/project-graph/project-graph.ts
+++ b/packages/nx/src/project-graph/project-graph.ts
@@ -14,6 +14,7 @@ import { workspaceRoot } from '../utils/workspace-root';
 import { performance } from 'perf_hooks';
 import { retrieveWorkspaceFiles } from './utils/retrieve-workspace-files';
 import { readNxJson } from '../config/nx-json';
+import { unregisterPluginTSTranspiler } from '../utils/nx-plugin';
 
 /**
  * Synchronously reads the latest cached copy of the workspace's ProjectGraph.
@@ -76,7 +77,7 @@ export async function buildProjectGraphWithoutDaemon() {
     await retrieveWorkspaceFiles(workspaceRoot, nxJson);
 
   const cacheEnabled = process.env.NX_CACHE_PROJECT_GRAPH !== 'false';
-  return (
+  const projectGraph = (
     await buildProjectGraphUsingProjectFileMap(
       projectConfigurations.projects,
       externalNodes,
@@ -86,6 +87,10 @@ export async function buildProjectGraphWithoutDaemon() {
       cacheEnabled
     )
   ).projectGraph;
+
+  unregisterPluginTSTranspiler();
+
+  return projectGraph;
 }
 
 function handleProjectGraphError(opts: { exitOnError: boolean }, e) {
diff --git a/packages/nx/src/project-graph/utils/retrieve-workspace-files.ts b/packages/nx/src/project-graph/utils/retrieve-workspace-files.ts
index 9ab713def47d8..7461fb70180ed 100644
--- a/packages/nx/src/project-graph/utils/retrieve-workspace-files.ts
+++ b/packages/nx/src/project-graph/utils/retrieve-workspace-files.ts
@@ -25,6 +25,7 @@ import {
   loadNxPlugins,
   loadNxPluginsSync,
   NxPluginV2,
+  unregisterPluginTSTranspiler,
 } from '../../utils/nx-plugin';
 import { CreateProjectJsonProjectsPlugin } from '../../plugins/project-json/build-nodes/project-json';
 import {
diff --git a/packages/nx/src/utils/nx-plugin.ts b/packages/nx/src/utils/nx-plugin.ts
index 7c93cc91c9ae4..4fde168d9874d 100644
--- a/packages/nx/src/utils/nx-plugin.ts
+++ b/packages/nx/src/utils/nx-plugin.ts
@@ -178,7 +178,7 @@ function getPluginPathAndName(
 
   // Register the ts-transpiler if we are pointing to a
   // plain ts file that's not part of a plugin project
-  if (extension === '.ts' && !tsNodeAndPathsRegistered) {
+  if (extension === '.ts' && !tsNodeAndPathsUnregisterCallback) {
     registerPluginTSTranspiler();
   }
 
@@ -369,14 +369,14 @@ export function resolveLocalNxPlugin(
   return localPluginCache[importPath];
 }
 
-let tsNodeAndPathsRegistered = false;
+let tsNodeAndPathsUnregisterCallback = undefined;
 
 /**
  * Register swc-node or ts-node if they are not currently registered
  * with some default settings which work well for Nx plugins.
  */
 export function registerPluginTSTranspiler() {
-  if (!tsNodeAndPathsRegistered) {
+  if (!tsNodeAndPathsUnregisterCallback) {
     // nx-ignore-next-line
     const ts: typeof import('typescript') = require('typescript');
 
@@ -390,8 +390,8 @@ export function registerPluginTSTranspiler() {
       ? readTsConfig(tsConfigName)
       : {};
 
-    registerTsConfigPaths(tsConfigName);
-    registerTranspiler({
+    const unregisterTsConfigPaths = registerTsConfigPaths(tsConfigName);
+    const unregisterTranspiler = registerTranspiler({
       experimentalDecorators: true,
       emitDecoratorMetadata: true,
       ...tsConfig.options,
@@ -401,8 +401,21 @@ export function registerPluginTSTranspiler() {
       inlineSourceMap: true,
       skipLibCheck: true,
     });
+    tsNodeAndPathsUnregisterCallback = () => {
+      unregisterTsConfigPaths();
+      unregisterTranspiler();
+    };
+  }
+}
+
+/**
+ * Unregister the ts-node transpiler if it is registered
+ */
+export function unregisterPluginTSTranspiler() {
+  if (tsNodeAndPathsUnregisterCallback) {
+    tsNodeAndPathsUnregisterCallback();
+    tsNodeAndPathsUnregisterCallback = undefined;
   }
-  tsNodeAndPathsRegistered = true;
 }
 
 function lookupLocalPlugin(importPath: string, root = workspaceRoot) {
@@ -412,7 +425,7 @@ function lookupLocalPlugin(importPath: string, root = workspaceRoot) {
     return null;
   }
 
-  if (!tsNodeAndPathsRegistered) {
+  if (!tsNodeAndPathsUnregisterCallback) {
     registerPluginTSTranspiler();
   }
 
@@ -452,6 +465,7 @@ function findNxProjectForImportPath(
 }
 
 let tsconfigPaths: Record<string, string[]>;
+
 function readTsConfigPaths(root: string = workspaceRoot) {
   if (!tsconfigPaths) {
     const tsconfigPath: string | null = ['tsconfig.base.json', 'tsconfig.json']