diff --git a/.bazelrc b/.bazelrc
index 01a3b4c7bb..67af89da30 100644
--- a/.bazelrc
+++ b/.bazelrc
@@ -10,6 +10,10 @@ common --enable_platform_specific_config
 # Needed by gRPC to build on some platforms.
 build --copt -DGRPC_BAZEL_BUILD
 
+# Avoid conflicting boringssl/protobuf system brew install
+# https://github.com/bazelbuild/bazel/issues/10472
+build:macos --copt=-isystem/usr/local/include
+
 # Set minimum supported C++ version
 build:macos --host_cxxopt=-std=c++14 --cxxopt=-std=c++14
 build:linux --host_cxxopt=-std=c++14 --cxxopt=-std=c++14