diff --git a/extensions/positron-python/pythonFiles/positron/positron_ipykernel/data_explorer.py b/extensions/positron-python/pythonFiles/positron/positron_ipykernel/data_explorer.py
index 123933dce15..76ee2e00d3c 100644
--- a/extensions/positron-python/pythonFiles/positron/positron_ipykernel/data_explorer.py
+++ b/extensions/positron-python/pythonFiles/positron/positron_ipykernel/data_explorer.py
@@ -273,7 +273,7 @@ def _get_schema(self, column_start: int, num_columns: int) -> TableSchema:
         for i, (c, dtype) in enumerate(zip(columns_slice, dtypes_slice)):
             if dtype == object:
                 column_index = i + column_start
-                if i not in self._inferred_dtypes:
+                if column_index not in self._inferred_dtypes:
                     self._inferred_dtypes[column_index] = infer_dtype(
                         self.table.iloc[:, column_index]
                     )
diff --git a/extensions/positron-python/pythonFiles/positron/positron_ipykernel/tests/test_data_explorer.py b/extensions/positron-python/pythonFiles/positron/positron_ipykernel/tests/test_data_explorer.py
index f2811b21a5a..453229da5c8 100644
--- a/extensions/positron-python/pythonFiles/positron/positron_ipykernel/tests/test_data_explorer.py
+++ b/extensions/positron-python/pythonFiles/positron/positron_ipykernel/tests/test_data_explorer.py
@@ -436,6 +436,27 @@ def test_pandas_get_schema(pandas_fixture: PandasFixture):
     assert result["columns"] == _wrap_json(ColumnSchema, bigger_schema[10:20])
 
 
+def test_pandas_wide_schemas(pandas_fixture: PandasFixture):
+    arr = np.arange(10).astype(object)
+
+    ncols = 10000
+    df = pd.DataFrame({f"col_{i}": arr for i in range(ncols)})
+
+    pandas_fixture.register_table("wide_df", df)
+
+    chunk_size = 100
+    for chunk_index in range(ncols // chunk_size):
+        start_index = chunk_index * chunk_size
+        pandas_fixture.register_table(
+            f"wide_df_{chunk_index}",
+            df.iloc[:, start_index : (chunk_index + 1) * chunk_size],
+        )
+
+        schema_slice = pandas_fixture.get_schema("wide_df", start_index, chunk_size)
+        expected = pandas_fixture.get_schema(f"wide_df_{chunk_index}", 0, chunk_size)
+        assert schema_slice["columns"] == expected["columns"]
+
+
 def _trim_whitespace(columns):
     return [[x.strip() for x in column] for column in columns]