diff --git a/conda/recipes/cuproj/meta.yaml b/conda/recipes/cuproj/meta.yaml
index 4721daefb..d65a983c6 100644
--- a/conda/recipes/cuproj/meta.yaml
+++ b/conda/recipes/cuproj/meta.yaml
@@ -63,7 +63,6 @@ requirements:
     - python
     - rmm ={{ minor_version }}
     - scikit-build-core >=0.7.0
-    - setuptools
     - proj
     - sqlite
   run:
diff --git a/conda/recipes/cuspatial/meta.yaml b/conda/recipes/cuspatial/meta.yaml
index 1bc68677f..b3ea40cb7 100644
--- a/conda/recipes/cuspatial/meta.yaml
+++ b/conda/recipes/cuspatial/meta.yaml
@@ -65,7 +65,6 @@ requirements:
     - python
     - rmm ={{ minor_version }}
     - scikit-build-core >=0.7.0
-    - setuptools
   run:
     {% if cuda_major == "11" %}
     - cudatoolkit
diff --git a/dependencies.yaml b/dependencies.yaml
index fa7b82381..7fe3fa2f6 100644
--- a/dependencies.yaml
+++ b/dependencies.yaml
@@ -232,7 +232,6 @@ dependencies:
       - output_types: [requirements, pyproject]
         packages:
           - wheel
-          - setuptools
   cuda_version:
     specific:
       - output_types: conda
diff --git a/python/cuproj/pyproject.toml b/python/cuproj/pyproject.toml
index 88066054f..8392dc75f 100644
--- a/python/cuproj/pyproject.toml
+++ b/python/cuproj/pyproject.toml
@@ -20,7 +20,6 @@ requires = [
     "ninja",
     "rmm==24.8.*",
     "scikit-build-core[pyproject]>=0.7.0",
-    "setuptools",
     "wheel",
 ] # This list was generated by `rapids-dependency-file-generator`. To make changes, edit ../../dependencies.yaml and run `rapids-dependency-file-generator`.
 
diff --git a/python/cuspatial/pyproject.toml b/python/cuspatial/pyproject.toml
index d174f8689..b2d6eddbd 100644
--- a/python/cuspatial/pyproject.toml
+++ b/python/cuspatial/pyproject.toml
@@ -21,7 +21,6 @@ requires = [
     "ninja",
     "rmm==24.8.*",
     "scikit-build-core[pyproject]>=0.7.0",
-    "setuptools",
     "wheel",
 ] # This list was generated by `rapids-dependency-file-generator`. To make changes, edit ../../dependencies.yaml and run `rapids-dependency-file-generator`.