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Pathway_Commons.4.All.BIOPAX.library.9606.gmt
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Pathway_Commons.4.All.BIOPAX.library.9606.gmt
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PID_smad2_3nuclearpathway HSPA8 AKT1 SMAD3/SMAD4/ER_alpha_(complex) SMAD3/SMAD4/MYOD_(complex) RUNX1-3 SMAD2-3/SMAD4/SP1/MIZ-1_(complex) Cbp/p300/SNIP1_(complex) Cbp/p300/PIAS3_(complex) SMAD3/E2F4-5/DP1/p107/SMAD4_(complex) SMAD2/SMAD2/SMAD4/FOXH1/NKX2-5_(complex) SMAD3/SMAD4/ATF3_(complex) SMAD3/SMAD4/DLX1_(complex) CBFB SAP18 FOXO1-3a-4 E2F4-5 SNIP1 SP1 Cbp/p300/Src-1_(complex) SMAD2/SMAD2/SMAD4/FOXH1_(complex) FOXH1 GATA3 SMAD3/SMAD4/IRF7_(complex) MAX RBBP7 RBBP4 RUNX2 SMAD3/SMAD4_(complex) CTBP1 VDR Cbp/p300/MSG1_(complex) SMAD2-3/SMAD4/SP1_(complex) KAT2B KAT2A DCP1A SKI SERPINE1 SMAD3/SMAD4/GATA3_(complex) SAP30 JUN SKI/SIN3/HDAC_complex/NCoR1_(complex) SMAD2/SMAD2/SMAD4/FOXH1/SMIF_(complex) TFE3 NKX2-5 DLX1 SMAD2-3/SMAD4/ARC105_(complex) FOS SMAD3/SMAD4/AR_(complex) SMAD2-3-active SMAD3/SMAD4/Max_(complex) Cbp/p300 MSG1/HSC70_(complex) IRF7 ESR1 HNF4A MEF2C SMAD3/SMAD4/TFE3_(complex) TFDP1 HDAC1 HDAC2 SMAD4 SMAD7 SMAD2 SMAD3 SMAD3/SMAD4/ATF2_(complex) NCOR1 CDK2-4 NCOA2 NCOA1 ZBTB17 SMAD2/SMAD2/SMAD4_(complex) CITED1 RBL1 TGIF/SIN3/HDAC_complex/CtBP_(complex) EP300 SMAD3/SMAD4/GR_(complex) SMAD3/SMAD4/JUN/FOS_(complex) PIAS3 PIAS4 SMAD3/SMAD4/VDR_(complex) SMAD3/SMAD4/HNF4_(complex) CEBPB MYOD1 SMAD2-3/SMAD4/FOXO1-3a-4_(complex) MED15 SMAD2-3/SMAD4/FOXO1-3a-4/CEBPB_(complex) SMAD3/SMAD4/RUNX1-3/PEBPB2_(complex) SIN3B TGIF2/HDAC_complex/SMAD3/SMAD4_(complex) SIN3A NR3C1 PIASy/HDAC_complex_(complex) SMAD3/SMAD4/MEF2C_(complex) AR SMAD3/SMAD4/SP1_(complex) SKIL HDAC_complex_(complex) TGIF1 SMAD2/SMAD2/SMAD4/SnoN/SIN3/HDAC_complex/NCoR1_(complex) SMAD3/SMAD4/RUNX2_(complex) TGIF2 ATF3 ATF2
REACTOME_REACT_115529 IL7R IL7_IL7RA_JAK1_IL2RG_JAK3_(complex) p-STAT5_(family) IL7_p(Y449)-IL7RA_JAK1_IL2RG_JAK3_PI3K-regulatory_subunits_(complex) IL7 PIK3R3 PIK3R2 PIK3R1 JAK1 PI3K-regulatory_subunits_(family) JAK3 IL7_IL7RA_JAK1_(complex) p(Y449)-IL7RA_JAK1_(complex) IL7_p(Y449)-IL7RA_JAK1_IL2RG_JAK3_(complex) HGF IL7_p(Y449)-IL7RA_JAK1_(complex) IL2RG IL7RA_JAK1_(complex) STAT5B STAT5A pre-pro-B_cell_growth-stimulating_factor_(complex) IL2RG_JAK3_(complex)
REACTOME_REACT_115902 RPN1 RPN2 SRP9 FAU Translocon-associated_Complex_(complex) RPL14 RPL15 RPL17 RPL10 RPL11 RPL12 RPL13 RPL18 RPL19 SRPR 40S_ribosomal_complex_(complex) UBA52 RPS3 RPL37A RPL8 SRP19 RPL6 RPL7 RPL27A RPL5 RPL3 EMBL_V00589 60S_ribosomal_complex_(complex) RPL7A cleaved_polypeptide_Translocon_(complex) RPS9 SRP14 RPL10A RPL9P7 SEC61_alpha_(family) SRP_receptor_SRP_ribosome_polypeptide+signal_(complex) membrane-bound_ribosome_mRNA_cleaved_polypeptide_(complex) RPLP2 RPLP1 RPLP0 RPL18A RPL35A RPS15A RPS7 RPS6 RPS5 RPS27A RPS2 RPL41 RPS8 RPS4Y1 SRPRB RPS15 Translocon_(complex) RPL13A SRP72 RPL4 RPS26 RPS27 RPS24 RPS25 RPS23 RPS20 RPS21 RPS28 RPS29 RPS4X EMBL_J01866 RPSA SRP_receptor_(complex) TRAM1 SRP68 RPS3A EMBL_M11167 RPS13 RPS12 RPS11 RPS10 RPS17 RPS16 RPL23A RPS14 RPS19 RPS18 ribosome_mRNA_polypeptide+signal_(complex) RPL3L DDOST EMBL_X03205 Translocon_TRAP_(complex) SRP54 RPL29 RPL28 RPL24 RPL27 RPL26 RPL21 RPL23 RPL22 SRP_polypeptide+signal_ribosome_(complex) SEC61G SEC61B signal_recognition_particle__endoplasmic_reticulum_targeting_(complex) 80S_monosome_(complex) RPL26L1 RPL38 RPL39 RPL36 RPL37 RPL34 RPL35 RPL32 RPL30 RPL31 RPL36A SSR1 SSR2 SSR3 SSR4 SEC61A1 SEC61A2
PID_SHC_mediated_cascade SRC SHC1 SOS1 GRB2 FGFR1_GRB2_SOS1_p-SHC_SRC_(complex) Complex_of_Activated_FGFR_with_SHC_(complex) GRB2_SOS1_(complex)
REACTOME_REACT_21346 kaiante_Receptors_(complex) Kainate_receptor-glutamate_complex_(complex)
REACTOME_REACT_163994 RASGRP2 IkB(alpha)_NF-kB_complex_(complex) DAG_p-5Y-PKC-theta_CBM_oligomer_oligo-K63-poly_Ub-TRAF6_activated_TAK1_complex_(complex) RASGRP4 NFKBIA MAP3K7 IKBKB RASGRP1 MALT1oligomer_TRAF6_(complex) IKBKG UBE2V1 DAG_p-5Y-PKC-theta_CBM_oligomer_TRAF6_oligomer_(complex) TAB1_TAB2/TAB3_TAK1_(complex) DAG_p-5Y-PKC-theta_p-S552_S645-CARMA1_(complex) PKC-theta_(open)__DAG_(complex) CBM_oligomer_TRAF6_oligomer_(complex) DAG_p-5Y-PKC-theta_CBM_oligomer_(complex) DAG_p-5Y-PKC-theta_CBM_oligomer_oligo-K63-poly_Ub-TRAF6_TAK1_TAB1_TAB2/3_(complex) NFKB1 RELA RasGRPs_DAG_Ca2+_(complex) MALT1 BCL10_oligomer_MALT1_oligomer_TRAF6_(complex) DAG_p-5Y-PKC-theta_CBM_oligomer_TRAF6_(complex) TRAF6 p-5Y-PKC-theta_DAG_(complex) CARD11 p-S177_S181-IKKB_IKKA_pUb-NEMO_(complex) CHUK BCL10_MALT1_(complex) DAG_p-5Y-PKC-theta_p-S552_S645-CARMA1_BCL10_MALT1_(complex) CalDAG-GEFs_(family) PRKCQ DAG_p-5Y-PKC-theta_p-S552_S645-CARMA1_oligomer_(complex) BCL10 p-CARMA1_oligomer_BCL10_MALT1_(CBM_complex)_(complex) DAG_p-5Y-PKC-theta_CBM_oligomer_oligo-K63-poly_Ub-TRAF6_(complex) CBM_oligomer_(complex) UBE2N TAB3 TAB2 TAB1 CBM_oligomer_oligo-K63-poly_Ub-TRAF6_oligomer_(complex) TRAF6-regulated_IKK_activator_1_(complex) NF-kB_complex_(complex) IKK_complex_with_phosphorylated_IKK_beta_(complex) CBM_oligomer_TRAF6_(complex) TAB2/3_(family) p-Y90-PKC-theta_DAG_(complex)
BIOCYC_PWY-5481 LDHAL6B LDHAL6A CT32_(complex) LDH-A_(complex) LDHA LDHB LDHC
REACTOME_REACT_160305 RBX1 FBXW7_WD_mutants_SKP1_CUL1_RBX1_(complex) SKP1 CUL1 NOTCH1
PID_aurora_kinase_pathway AURKA AURKB AURKC
REACTOME_REACT_4 Cyclin_D1_Cdk4_(complex) CCND1 ubiquitin_(family) UBC phospho(T286)-Cyclin_D1_Cdk4_(complex) UBA52 CDK4 multi-ubiquitinated_phospho-(T286)_Cyclin_D1_(complex)
BIOCYC_PWY-5996 SCD ACOT1 oxidized_cytochrome_<i>b<sub>5</sub></i> a_ferrocytochrome_<i>b<SUB>5</SUB></i> SCD5 FADS1 ACOT4 FADS2 ACOT2 FADS6
PID_Pausing_and_recovery_of_Tat_mediated_HIV_1_elongation NELFB TCEB2 TCEB1 NELFA NELFE TCEB3 NELF_complex_(complex) CCNT1 Elongin_B_C_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) P-TEFb(Cyclin_T1_Cdk9)_complex_(complex) SSRP1 phospho-Spt5 HIV-1_Tat-containing_paused_processive_elongation_complex_(complex) CDK9 FACT_complex_(complex) Tat_P-TEFb(Cyclin_T1_Cdk9)_complex_(complex) ELL SUPT16H Elongin_Complex_(complex) TCEA1 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B TAT_protein POLR2L CTDP1 POLR2I POLR2H POLR2K POLR2J GTF2F1 NELFCD GTF2F2 HIV-1_Tat-containing_processive_elongation_complex_(complex) SUPT4H1 DSIF_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex)
REACTOME_REACT_18319 Metabotropic_glutamate_receptors_L-Glutamate_(complex) TAS2R20 GPRC6A_receptor_GPRC6A_ligands_(complex) GABAB_receptor_GABA_(complex) GABBR1 GABBR2 T2Rs_Bitter-tasting_compounds_(complex) Sweet_taste_receptor_(complex) TAS2R60 TAS2R50 Umami_taste_receptor_(complex) TAS2R30 CASR TAS2R38 TAS2R39 TAS2R19 T2Rs_(family) TAS2R14 TAS2R16 TAS2R31 TAS2R10 TAS2R13 Umami_taste_receptor_L-glutamate_(complex) GPRC6A GABAB_receptor_(complex) TAS2R8 TAS2R9 Sweet_taste_receptor_sweet_taste_stimuli_(complex) TAS2R7 CASR_Calcium_(complex) TAS2R5 TAS2R3 TAS2R1 TAS2R43 TAS2R42 TAS2R41 TAS2R40 TAS2R46 TAS2R45 TAS1R1 TAS1R3 TAS1R2 TAS2R4
PID_Dopamine_receptors DRD2__3__4_dopamine_(complex) DRD2__3__4 DRD1__5_dopamine_(complex) DRD1__5
REACTOME_REACT_6918 linear_duplex_viral_DNA_(complex) UniProt_P04591_gag IN_bound_to_sticky_3prime_ends_of_viral_DNA_in_PIC_(complex) UniProt_P04585_gag-pol XRCC5 XRCC4 XRCC6 viral_PIC_proteins_(complex) Matrix_(family) LIG4 Ku_proteins_bound_to_viral_DNA_(complex) XRCC4_DNA_ligase_IV_complex_(complex) viral_DNA_Ku_proteins_XRCC4_DNA_ligase_IV_complex_(complex) HMGA1 UniProt_P04618_rev UniProt_P05919_vpu 2-LTR_form_of_circular_viral_DNA_(complex) Ku70_Ku80_heterodimer_(complex) IN_bound_to_sticky_3prime_ends_of_viral_DNA_(complex) viral_DNA_with_3prime_sticky_ends_(complex) PSIP1 UniProt_P69726_vpr UniProt_P69723_vif BANF1 p6_protein_(family)
REACTOME_REACT_1574 Cyclin_E_(family) Cyclin_E_phospho-Cdk2_Complex_(complex) CCNE2 CDKN1B CDKN1A CCNE1 Cyclin_E2_phospho-Cdk2_complex_(complex) RB1 Cyclin_E_Cdk2_complex_(complex) p21/p27_(family) CDK2 Cyclin_E_Cdk2_p21/p27_complex_(complex) Cyclin_E_Phosho-Cdk2_(Thr_160)_(complex) Cyclin_E1_phospho-Cdk2_complex_(complex) Cyclin_E_Cdk2_complexes_(complex) Cyclin_E_Phospho-Cdk2(Thr160)_Rb_complex_(complex)
PID_CRMPs_in_Sema3A_signaling Cdk5_phosphorylated_CRMP_s_1-5 pCRMP_s_tetramers_(S522)_(complex) Nrp-1_PlexinA_Fyn_pCdk5_(complex) NRP-1_pPlexin-A_Fyn_(complex) Sema3A_NP-1_Plexin-A_Fes_CRMP_(complex) Phosphorylated_Plexin-A Fes_phosphorylated_CRMP_s_1-5 Sema3A_NRP-1_pPlexin-A_fyn_(complex) FYN CDK5R1 pCdk5_p35_(complex) pCRMP_s_tetramers_(S522_S518_T509_T514)_(complex) pCRMP_s_tertramers_(Y499)_(complex) Sema3A_Nrp-1_PlexinA_Fyn_pCdk5_(complex) Plexin_bound_with_Fyn_(complex) Plexin-A_(1-4) Nrp-1_PlexinA_Fyn_Cdk5_pCRMP_s_(S522_S518_T509_T514)_(complex) FES PlexinA_Fyn_Cdk5_pCRMP_s_(complex) Nrp-1_PlexinA_Fyn_Cdk5_pCRMP_s_(complex) GSK3beta_phosphorylated_CRMP_s_1-5 NRP1 SEMA3A Nrp-1_complexed_with_PlexinA_Fyn_(complex) PlexinA_Fyn_Cdk5_pCRMP_s_(S522_S518_T509_T514)_(complex) Fyn_pCdk5_(complex) GSK3B Sema3A_Nrp-1_PlexinA_Fyn_(complex) CDK5 PlexinA_Fyn_pCdk5_(complex) Sema3A_NRP-1_pPlexin-A_Fyn_Fes_(complex) Sema3A_dimer_(complex) Sema3A_Nrp-1_PlexinA_Fyn_Cdk5_pCRMP_s_(complex)
REACTOME_REACT_8028 C5b_C6_complex_(complex) C5b_(complex) C9 C8_(complex) C8A C8B C5b_C6_C7_C8_complex_(complex) C8G C5b_C6_C7_complex_(complex) Membrane_Attack_Complex_(complex) C7 C6 C5
PID_ahsppathway HMBS AHSP HbH_(complex) ALAD HbA_(complex) HB-beta_(complex) UROS HB-alpha/O2_(complex) HB-alpha_(complex) CPOX ALAS2 alpha-globin/HEME/alpha-globin/HEME/alpha-globin/HEME/alpha-globin/HEME_(complex) alpha-globin UROD HBB FECH
REACTOME_REACT_14835 SNW1 MAML2 MAML3 MAML1 NOTCH4 NICD_(family) RBPJ KAT2B KAT2A NOTCH1 MAMLD1 NOTCH2 MAML_(family) CBP_(family) CSL_NICD_coactivator_complex_(complex) NOTCH3 SKIP_(family) PCAF_(family) CREBBP
REACTOME_REACT_1619 TRAF2 TRADD TRAF2_TRADD_RIPK1_(complex) TNF-alpha_TNF-R1_(complex) TNF-alpha_trimer_(complex) TNFRSF1A TNF-alpha_trimer__soluble_form_(complex) RIPK1 TNF-alpha_trimer_TNF-R1_trimer_(complex) TNF soluble_TNF-alpha_TNF-R1_(complex) CASP8 FADD TNF-alpha_TNF-R1_TRADD_RIPK1_TRAF2_(complex) TRADD_TRAF2_RIP1_FADD_procaspase-8_(complex) TRADD_TRAF2_RIP1_FADD_(complex)
REACTOME_REACT_6282 UniProt_P03433_PA RNP_Complex_Karyopherin_alpha_(complex) UniProt_P03428_PB2 KPNA1 EMBL_AF389122_H1N1_Genomic_RNA_Segment_8 KPNB1 UniProt_P03466_NP EMBL_AF389116_H1N1_Genomic_RNA_Segment_2 EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 EMBL_AF389119_H1N1_Genomic_RNA_Segment_5 EMBL_AF389117_H1N1_Genomic_RNA_Segment_3 EMBL_AF389120_H1N1_Genomic_RNA_Segment_6 RNP_Karyopherin_alpha_Karyopherin_beta_complex_(complex) UniProt_P03431_PB1 EMBL_AF389115_H1N1_Genomic_RNA_Segment_1 Ribonucleoprotein_(RNP)_Complex_(complex) EMBL_AF389118_H1N1_Genomic_RNA_Segment_4
BIOCYC_PWY-7197 NME4 NME5 NME7 NME1 NME2 NME3 CMPK1 CMPK2 DTYMK NME2P1 nucleoside_diphosphate_kinase_(complex)
PID_Neurotransmitter_Clearance_In_The_Synaptic_Cleft ACHE SLC22A2
PID_Processing_of_Intronless_Pre_mRNAs NCBP1 NCBP2 CF_II_(complex) capped_intronless_pre-mRNA_CBC_complex_(complex) CPSF7 NUDT21 CPSF3 CPSF2 CPSF1 Cleavage_and_polyadenylation_specificity_factor_(complex) PAPOLA PCF11 CstF_CPSF_capped_intronless_pre-mRNA_CBC_complex_(complex) PABPN1 CF_I_(complex) Cleavage_Stimulation_Factor_(complex) CLP1 CSTF1 CSTF3 CSTF2 CPSF_capped_intronless_pre-mRNA_CBC_complex_(complex) intronless_pre-mRNA_cleavage_complex_(complex)
PID_Removal_of_the_Flap_Intermediate POLA2 POLA1 Processive_complex_Okazaki_fragment_Flap_RPA_heterotrimer_(complex) FEN1 RPA3 Processive_complex_Okazaki_fragment_Flap_(complex) RNA_primer-DNA_primer_origin_duplex_PCNA_(complex) RPA_heterotrimer_(complex) DNA2 DNA_Pol_alpha_primase_(complex) POLD1 POLD2 POLD3 POLD4 PRIM2 PRIM1 PCNA Processive_complex_nicked_DNA_from_adjacent_Okazaki_fragments_(complex) RNA_primer-DNA_primer_origin_duplex_(complex) PCNA_homotrimer_(complex) RNA_primer_origin_duplex_DNA_polymerase_alpha_primase_complex_(complex) Processive_complex_(complex) Processive_complex_Okazaki_fragment_Flap_RPA_heterotrimer_dna2_(complex) RPA1 DNA_Polymerase_delta_tetramer_(complex) Processive_complex_Okazaki_fragment_complex_(complex) RPA2
PID_RSK_activation Ribosomal_S6_kinase MAPK1 Phospho(S221_S363_S380_T573)-_ribosomal_S6_kinase PDPK1 Phospho(S363_S380_T573)-ribosomal_S6_kinase Phospho(S363_S380_T573)-_ribosomal_S6_kinase
PID_mRNA_Splicing___Major_Pathway NCBP1 NCBP2 Spliceosomal_E_Complex_(complex) PRPF8 SRSF11 NUDT21 U1_snRNP_(complex) PRPF4 PRPF6 EMBL_V00590_U1A_snRNA hnRNP_proteins_(complex) PCF11 PTBP1 U2_snRNP_(complex) MAGOH DHX9 SF3A2 SF3A3 TFIIF_(complex) SNRPD3 EMBL_X59360_U2_snRNA EMBL_X59362_U6_snRNA GTF2F1 SNRPD2 SNRPD1 GTF2F2 SNRPG RNA_polymerase_II_(phosphorylated)_TFIIF_complex_(complex) U4_snRNP_U6_snRNP_complex_(complex) YBX1 CD2BP2 Cap_Binding_Complex_(CBC)_(complex) FUS U4_snRNP_(complex) DHX38 U6_snRNP_(complex) CCAR1 SRSF5 SRSF4 SRSF7 Cleavage_and_polyadenylation_specificity_factor_(complex) SRSF1 RNA_Polymerase_II_(unphosphorylated)_TFIIF_complex_(complex) SRSF3 SRSF2 U2AF1 U2AF2 SRSF9 EFTUD2 PCBP2 SF3A1 EMBL_X59361_U4_snRNA PCBP1 Splicing_Factor_3B_(complex) SMC1A NHP2L1 RNPS1 SNRNP200 ALYREF RNA_Polymerase_II_holoenzyme_complex_(phosphorylated)_(complex) POLR2E SF3A_(complex) POLR2G POLR2F POLR2A POLR2C POLR2B POLR2L POLR2I POLR2H POLR2K POLR2J SNRPB2 DNAJC8 POLR2D SF3B14 snRNP_Sm_core_complex_(complex) capped__methylated_pre-mRNA_CBC_Complex_(complex) PHF5A CF_II_(complex) U5_snRNP_(complex) Exon_Junction_Complex_(complex) SNRPA1 lariat_containing_5prime-end_cleaved_mRNA_CBC_complex_(complex) HNRNPH1 HNRNPH2 Magoh-Y14_complex_(complex) RBM8A HNRNPR HNRNPU Cleavage_Stimulation_Factor_(complex) Spliceosomal_A_Complex_(complex) HNRNPK HNRNPL HNRNPM pre-EJC_complex_(complex) HNRNPC HNRNPD HNRNPF SUGP1 HNRNPA3 HNRNPA0 HNRNPA1 RNA_Polymerase_II_holoenzyme_complex_(unphosphorylated)_(complex) CF_I_(complex) Spliceosomal_Active_C_Complex_(complex) HNRNPUL1 SNRNP70 SRRM1 CDC40 RBM5 SF3B5 SF3B4 SF3B1 SF3B3 SF3B2 Spliceosomal_active_C_complex_with_lariat_containing__5prime-end_cleaved_pre-mRNP_CBC_complex_(complex) CPSF7 TXNL4A CSTF2 CPSF3 CPSF2 CPSF1 UniProt_O43831_NFX.1 HNRNPA2B1 EMBL_X04293_U5_snRNA PABPN1 LSM2 SRSF6 SNRPB SNRPA SNRPF PAPOLA SNRPE DDX23 SNRNP40 CLP1 CSTF1 CSTF3 RBMX UPF3B Spliceosomal_B_Complex_(complex) Cleavage_and_Polyadenylation_Complex_(complex)
PID_fra_pathway NFATC2 NFAT1-c-4-active Fra2/JUNB_(complex) JUNB JUND Fra1/JUND_(complex) Fra2/JUND_(complex) JUN USF2 FOSL1 Fra1/p300/JUNB/JUND/SP1_(complex) JUNB/Fra1/NFAT1-c-4_(complex) Fra1/FIAT_(complex) TXLNG SP1 FOSL2 Fra2/ATF4_(complex) Fra2/JUN_(complex) EP300 Fra1/JUN_(complex) Fra1/JUNB_(complex) Fra1/USF2_(complex) ATF4 Fra1/JUNB/NFAT1_(complex)
REACTOME_REACT_160205 NTM-NEC_2_heterodimer_(complex) RPS27A NOTCH2_fragment_DLL/JAG_(complex) NOTCH2/Fringe-modified_NOTCH2_(complex) CNTN1 MDK MDK_homodimer_(complex) NTM-NEC2-Notch_ligand_complex_(complex) CNTN1_NOTCH2_(complex) JAG2 JAG1 DLL/JAG_(family) MDK_NOTCH2_(complex) DLL1 DLL4 JAG2_NOTCH2_(complex) JAG1_NOTCH2_(complex) ubiquitin_(family) DLL4_NOTCH2_(complex) NOTCH2 UBA52 Ub-DLL/JAG_NOTCH2_(complex) UBB UBC DLL1_NOTCH2_(complex)
BIOCYC_PWY-46 ODC_(complex) ADC ODC1
BIOCYC_PWY-6129 DOLK SRD5A3 DHDDS
PID_Monoamines_are_oxidized_to_aldehydes_by_MAOA_and_MAOB__producing_NH3_and_H2O2 MAOB-FAD_complex_(complex) MAOB MAOA MAOA-FAD_complex_(complex)
PID_deathpathway TNFSF12 ACTA1 ADPRT_(cleaved) TNFRSF25 SPTAN1 RIPK1 TNFSF10 TRADD GAS2_(cleaved) DR3/TRADD/FADD/TRAF2/RIP/Caspase_8/Caspase_10/APO-3L_(complex) BID DR4/5/Caspase_8/Caspase_10/APO-2L_(complex) FADD TRAF2 PARP1 LMNA_(cleaved) CASP10 LMNA DR4/5 CASP6 CASP7 CASP3 ACTA1_(cleaved) CASP8 MAP3K14 SPTAN1_(cleaved) GAS2
BIOCYC_PWY-6317 GALT GALE GALK1 GALM
PID_Transport_of_glucose_and_other_sugars__bile_salts_and_organic_acids__metal_ions_and_amine_compounds MATE1/2 Urea_transporters CTL1-5 SLC10A6 SLC5A7
PID_Synthesis_of_Dopamine DDC Tyrosine_3-monooxygenase Tyrosine_3-monooxygenase_(Fe2+_cofactor)_(complex) Dopa_decarboxylase_homodimer_(pyridoxal_phosphate_cofactor)_(complex)
PID_g2pathway PI4KA CDKN1A ATM PRKDC ATR GADD45A Cyclin_B/CDC2_(complex) CDC34 YWHAH WEE1 CHEK2 MYT1 BRCA1 CDKN2D p53/MDM2_(complex) MDM2 RPS6KA1 CCNB1 TP53 RASGRF1 MDM2/p19_(complex) CDC25/14-3-3_(complex) SFN CDK1 14-3-3-sigma/CDC2/CYCLIN_B_(complex) CHEK1
PID_soddpathway TNF_R TNF BAG4 TNF/TNF_R/SODD_(complex)
REACTOME_REACT_116145 Cam-PDE_1_homodimer_(complex) active_Cam-PDE_1_(complex)
PID_RNA_Pol_II_CTD_phosphorylation_and_interaction_with_CE1 ERCC2 ERCC3 HIV-1_transcription_complex_containing_extruded_transcript_to_+30_(complex) RNA_Pol_II_with_phosphorylated_CTD__CE_complex_with_activated_GT_(complex) RNGTT RNA_Polymerase_II_(unphosphorylated)_TFIIF_complex_(complex) phospho-Spt5 HIV-1_transcription_complex_with_(ser5)_phosphorylated_CTD_containing_extruded_transcript_to_+30_(complex) RNMT RNA_Pol_II_with_phosphorylated_CTD__CE_complex_(complex) GTF2H3 GTF2H2 GTF2H1 RNA_Polymerase_II_holoenzyme_complex_(unphosphorylated)_(complex) RNA_Polymerase_II_holoenzyme_complex_(phosphorylated)_(complex) GTF2H4 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L MNAT1 CE_Pol_II_CTD_Spt5_complex_(complex) POLR2I POLR2H POLR2K POLR2J GTF2F1 GTF2F2 RNA_polymerase_II_(phosphorylated)_TFIIF_complex_(complex) TFIIH_(complex) CDK7 CAK_(complex) CCNH
PID_Inhibition_of_Host_mRNA_Processing_and_RNA_Silencing PABPN1 NS1_PAB_II_Complex_(complex) UniProt_P03496_NS NS1_Homodimer_(complex) CPSF4 CPSF_NS1_Complex_(complex)
PID_Calmodulin_induced_events phospho-CREB_dimer_(complex) CALM1 GRK2_calmodulin_(complex) Protein_kinase_C_(alpha__gamma__delta) Active_Calmodulin_(complex) CREB1 active_PKC_(alpha__gamma__delta)_(complex) ADRBK1
PANTHER_P00025 Fused Complex_(Sap18/Su(fu)/_Cubitus_interruptus_repressor)_(complex) Microtubule Debra Patched Complex_(Su(fu)/Slimb/_Cubitus_interruptus)_(complex) Smoothened Cubitus_interruptus_repressor Complex_(Cubitus_interruptus_repressor/Su(fu))_(complex) Complex_(Costal2/Smoothened/_Fused)_(complex) Complex_(Su(fu)/Cubitus_interruptus)_(complex) Complex_(Cubitus_interruptus/Su(fu)/_Slimb)_(complex) Complex_(Patched/Hedgehog)_(complex) Su(fu) Complex_(CBP/Cubitus_interruptus)_(complex) Complex_(Costal2/Fused/_Smoothened)_(complex) Cubitus_interruptus Hedgehog Slimb CBP Sap18 Costal2
REACTOME_REACT_12005 MAP2K2 MAPK1 phospho-ERK-2_dimer_(complex) MEK2_ERK-2_(complex) phospho-ERK-2_MEK2_(complex)
BIOCYC_BGALACT-PWY lactase_phlorizin_hydrolase_precursor_lactase_glycosylceramidase//lactase//phlorizin_hydrolase GLB1L3 GLB1
PID_Collagen_adhesion_via_Gp_IV GP_IV___Collagen_IV_complex_(complex) Collagen_I_(complex) CD36 COL1A2 Collagen_I_(alpha_1__alpha_1__alpha_2)_(complex) COL1A1
PID_s1p_meta_pathway SGPL1 S1PR5 S1P/S1P3/Gq_(complex) S1P1/S1P_(complex) S1PR3 S1PR2 S1P/S1P2/G12/G13_(complex) S1PR1 Gq_family S1P/S1P5/G12_(complex) SPHK GNA12 GNA13 Gi_family S1P/S1P4/Gi_(complex) S1PR4 ABCC1 SGPP1
PID_mitochondriapathway BCL2L1 APAF-1/Caspase_9_(complex) BIK BID BAX BAK1 Porin/VDAC BCL-XL/BCL-2/BIK_(complex) BAX/BCL-2/BCL-XL_(complex) DIABLO CYCS CASP9 BCL-XL/BCL-2/BAK_(complex) AIFM1 IAP APAF1 BCL2
PID_Synthesis_of_Dolichyl_phosphate DOLK DOLPP1
BIOCYC_PWY-5754-1 TAT tyrosine_transaminase_(complex)
REACTOME_REACT_1041 MAD2_CDC20_complex_(complex) MAD2L1 CDC20
PANTHER_P00039 Complex_(EAAT/Glutamate)_(complex) Complex_(mGluR_1/5/_Glutamate)_(complex) mGluR4/6/7/8 Complex_(Vglut/Glutamate)_(complex) Complex_(GTP/G-Protein)_(complex) Complex_(mGluR_5/Glutamate)_(complex) Ca(2+) Complex_(SNARE_Complex/Ca2+)_(complex) CSTA A/K Complex_(mGluR4/6/_7/8/_Glutamate/G-Protein/_GDP)_(complex) Complex_(NMDA/Glutamate)_(complex) KNG1 PKA SNARE_Complex NMDA CST1 G-Protein Complex_(A/K/_Glutamate)_(complex) CST4 Vglut
PID_Formation_of_Fibrin_Clot__Clotting_Cascade_ F2 F9 factor_IXa_(complex) Activated_thrombin_(factor_IIa)_(complex) F10 factor_Xa_(complex)
REACTOME_REACT_6772 EEF2K RPS6 EIF4G1 EIF4B
REACTOME_REACT_169436 p-p38_MAPK_p-MAPKAPK2/3_(complex) p14-ARF_MDM2_TP53_(complex) MOV10 HIST1H4F TNRC6C TNRC6B TNRC6A Histone_H3_(family) MAPKAP2/MAPKAP3_(family) p16-INK4a/p14-ARF_mRNA__miR-24_Nonendonucleolytic_RISC_(complex) H2AFB1 MAP3K5 PHC1 PHC3 PHC2 JNKs__MAPK8_MAPK9_MAPK10_(family) H2BFS CDKN2C CDKN2A phospho-p38_MAPK__MAPKAPK2/3_(complex) CDKN2D AP-1(cJun_cFos)_phosphorylated_(complex) HIST3H2BB Histone_H2B_(family) MDM2 CDKN2A_Gene_H3K27Me3-Nucleosome_PRC1.4_(complex) MDM2_TP53_(complex) Cdk4/6_INK4A_complex_(complex) H2AFX H2AFZ RBBP4 UBA52 phospho-p38_MAPK__MAPKAPK5_(complex) UBB UBC Nucleosome_(Deacetylated)_(complex) RNF2 Histone_H3_with_trimethylated_lysine_27_(family) MAPK11 MAP_kinase_p38_alpha/beta_(family) RBBP7 CDK4-6_(family) INK4A_(family) EED MAPKAPK3 MAPKAPK2 UBIQ_HUMAN_(family) TP53_Tetramer_(complex) JUN Ub-TP53_(complex) p-MKK3/p-MKK6_(family) SUZ12_EED_EZH2_RpAp46_RpAp48_(complex) H3F3B Nonendonucleolytic_Argonaute_(family) p38_MAPK_MAPKAPK5_(complex) FOS JMJD3_Fe2+_(complex) CDKN2A_Gene_H3K27Me3-Nucleosome_(complex) HIST1H2BF HIST2H3C HIST1H2BA HIST1H2BB SCMH1 HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H2BH HIST1H2BJ HIST1H2BK HIST1H2BD TP53 miR-24_Nonendonucleolytic_Minimal_RISC_(complex) RING1 PRC1.4_(complex) AGO4 AGO1 AGO3 phosphorylated_JNKs__MAPK8_MAPK9_MAPK10_(family) MAPK14 MAPK10 ASK1_Thioredoxin_(complex) CBX8 CBX6 CBX4 Histone_H2A_(family) CBX2 HIST1H2AD KDM6B MAPK8 MAPK9 HIST2H2AA4 MKK3/MKK6_(family) p-2S-cJUN_p-2S_2T-cFOS_KDM6B_Gene_(complex) Ub-MDM2_(complex) CDKN2A_Gene_Nucleosome_(complex) Active_MAPKAP_kinase_(family) CDKN2A_Transcript_Variant_4 CDKN2A_Transcript_Variant_1 p-S37-TP53_Tetramer_(complex) CDK4 CDK6 phospho-p38_MAPK_p-T-182-MAPKAPK5_(complex) p-PRC1.4_complex_(complex) CDKN2B MAP2K4 MAP2K3 EZH2 MAP2K6 HIST2H2BE HIST1H2AJ DP-1_E2F1/2/3_(complex) HIST1H2AC HIST1H2AB Nucleosome_with_H3_Trimethylated_at_Lysine-27_(complex) TXN p38_MAPK_MAPKAPK2/3_(complex) EZH2_Gene_E2F1/2/3_DP1/2_(complex) Phosphorylated_JNKs__MAPK8__MAPK9__MAPK10_(family) SUZ12 EED_Gene_E2F1/2/3_DP1/2_(complex) TNRC6_(GW182)_(family) BMI1 HIST1H3C Cell_cycle_promoting_E2Fs_(family) HIST2H2AC SUZ12_Gene_E2F1/2/3_DP1/2_(complex) E2F3 E2F2 E2F1 Phospho-MAP_kinase_p38_alpha/beta_(family) TFDP1 miR-24_Nonendonucleolytic_RISC_(complex)
PID_Homologous_DNA_pairing_and_strand_exchange BRIP1
PID_faspathway2 PRKDC CASP10 PAK1_(cleaved) PAK2_(cleaved) MAP2K4 DAXX PRKDC_(cleaved) FAS MAP3K1 MAP3K7 RB1 CFLAR FAS/DAXX/FADD/Caspase_10/FAS_L_(complex) FADD MAPK8 MAP3K1_(cleaved) I-FLICE/RIP2_(complex) FAF1 FAS_L/FAS/DAXX/FADD/FAF1/Caspase_10_(complex) FASLG RB1_(cleaved) CASP7 CASP3 PTPN13 CASP8 RIPK2 PAK1 PAK2
BIOCYC_GLYSYN-PWY SHMT2 SHMT1
PID_vifpathway HIV-1/VIF/gag-pol/env_(complex) VIF VIF/Hck_(complex) APOBEC3G CXCR4 gag-pol CD4 HIV-1 env HCK CD4/CD4/CXCR4_(complex) HIV-1/VIF_(complex)
REACTOME_REACT_682 AHCTF1 PLK1 CCAN_network_(complex) CENP-(H_I__K)_complex_(complex) KIF2A KIF2C KIF2B BUB1B MAPRE1 CENPO CENPN CENPM CENPL CENPK CENPI CENPH CENPF CENPE CENPC RANGAP1 CENPA CENPT PAFAH1B1 CENPQ CENPP NUF2 PPP2CA PPP2CB Chromosome_passenger_complex_(complex) SPC24 NSL1 SEH1L ZWINT NUP85 MIS12 NDC80_complex_(complex) B9D2 XPO1 RZZ_complex_(complex) Mitotic_checkpoint_complex_(complex) Microtubule-bound_kinetochore_(complex) INCENP Nup107-160_complex_(complex) BUB3 SEC13 SGOL1 SGOL2 ZWILCH SPDL1 PP2A_(complex) CDC20 SPC25 PPP2R5D PPP2R5E PPP2R5A PPP2R5B PPP2R5C NUP133 DSN1 NDC80 Kinetochore_(complex) ERCC6L KNTC1 RANBP2 PP2A-subunit_A_(family) NUP107 ZW10 TAOK1 KMN_network_(complex) PPP2R1A PPP2R1B MAD2L1 RPS27 BIRC5 PP2A-catalytic_subunit_C_(family) ITGB3BP BUB1 NDE1 APITD1 MAD1L1 NUP98 NUDC NUP43 SKA1 CLIP1 SKA2 AURKB CENP-O_complex_(complex) CDCA8 Mis12_complex_(complex) CLASP2 CLASP1 NUP160 KIF18A PP2A_regulatory_subunit_B56_(family) CASC5 NDEL1 RCC2 PPP1CC PMF1 NUP37 MLF1IP CKAP5
REACTOME_REACT_12564 THEM4 Phospho-AKT_(family) AKT_PIP3_THEM4/TRIB3_(complex) Active_AKT_(family) AKT1 AKT2 AKT3 TRIB3 AKT_PIP3_(complex) THEM4/TRIB3_(family) AKT_(family)
REACTOME_REACT_9000 Cam-PDE_1_homodimer_(complex) active_Cam-PDE_1_(complex)
PID_Pyrimidine_salvage_reactions UPP1 CDA thymidine_phosphorylase_dimer_(complex) UCK1 thymidine_kinase_1__soluble_holoenzyme_(complex) UCK2 deoxycytidine_kinase_holoenzyme_(complex) TYMP TK2 TK1 UCK1_tetramer_(complex) cytidine_deaminase-Zn_complex_tetramer_(complex) UPP1_dimer_(complex) UCK2_tetramer_(complex) DCK
PID_Signaling_by_EGFR SRC LRIG1 EGF_Phospho-EGFR_(Y992__Y1068__Y1086__Y1148__Y1173)_dimer_(complex) p21_RAS EGFR EGF_Phospho-EGFR_(complex) p21_RAS_GTP_(complex) GRB2 EGF_EGFR_dimer_(complex) ADAM_metalloprotease_Zinc_cofactor_(complex) ADAM_metalloprotease EGF EGF_EGFR_(complex)
PID_TCR_signaling CD3_epsilon_gamma_(complex) CD3_epsilon__CD3_gamma_with_phosphorylated_ITAM_(complex) Activated_ZAP-70_(complex) CD3_epsilon__CD3_delta_with_phosphorylated_ITAMs_(complex) Antigen-bearing_MHC_Class_II__TCR_complex_CD4__Lck_phosphorylated_at_Tyr394_(complex) TCR_chain_beta CD3_epsilon_delta_(complex) MHC_Class_II_bearing_antigen_peptide_(complex) LCK CD4 T-cell_receptor_complex_(complex) CD247 TCR_chain_alpha T-cell_receptor_complex_with_phosphorylated_ITAMs_(complex) T-cell_receptor_(complex) CD3_zeta_dimer_with_phosphorylated_ITAMs_(complex) CD3G CD3D CD3E ZAP70 Antigen-bearing_MHC_Class_II__TCR_with_phosphorylated_ITAMs_CD4_(complex)
PANTHER_P00036 Complex_(Receptor_subunit_alpha/Receptor_subunit_beta/_Signaling_subunit/Interleukin)_(complex) c-fos Ets MNK1/2 BAD eNOS Jak Complex_(Grb2/Shc/_SOS)_(complex) IRS-1/2 ASS1 MAPKAPK2 ERK FKHRL1 AMBP PDK1/2 OAS1 SOS Grb2 p21CIP1 Ikk GSK3 SPINK1 Receptor_subunit_beta ELK SRF PI3K Src-like Signaling_subunit Shc Raf Receptor_subunit_alpha MEK p27KIP1 p90RSK STAT_(complex) Interleukin
REACTOME_REACT_6173 PABPN1 NS1_PAB_II_Complex_(complex) UniProt_P03496_NS NS1_Homodimer_(complex) CPSF4 CPSF_NS1_Complex_(complex)
REACTOME_REACT_18302 GPR17 LTB4R2 LTB4_receptors_(family) GPR17_cysLTs_(complex) Cysteinyl_leukotriene_receptors_(family) LTB4R LTB4_receptors_LTB4_(complex) CYSLTR2 Cysteinyl_leukotriene_receptors_Cysteinyl_leukotrienes_(complex) CYSLTR1
PID_Regulation_of_AMPK_activity_via_LKB1 RPTOR AMPK_gamma Phosphorylated_AMPK_heterotrimer_AMP_(complex) STK11 PPM1A AMPK_alpha Phosphorylated_AMPK_alpha AMPK_heterotrimer_(complex) MO25 LKB1_STRAD_MO25_(complex) STRAD Phosphorylated_AMPK_heterotrimer_(complex) AMPK_beta
REACTOME_REACT_163910 NOTCH2_Coactivator_Complex_FCER2_gene_(complex) MAML2 MAML3 GZMB FCER2 RBPJ MAML1 CREB1 NOTCH2_Coactivator_Complex_(complex) NOTCH2_Coactivator_Complex_HES1_gene_(complex) MAMLD1 NOTCH2 NOTCH2_coactivator_complex_p-S133-CREB1_EP300_GZMB_Gene_(complex) MAML_(family) HES1 EP300 HES5 NOTCH2_Coactivator_Complex_HES5_gene_(complex)
PID_Lagging_Strand_Synthesis PCNA POLA2 POLA1 DNA_polymerase_alpha_primase_(complex) POLD2 RNA_primer-DNA_primer_origin_duplex_(complex) POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 PCNA_homotrimer_(complex) RNA_primer_origin_duplex_DNA_polymerase_alpha_primase_complex_(complex) POLD4 Processive_complex_(complex) RNA_primer-DNA_primer_origin_duplex_PCNA_(complex) PRIM1
BIOCYC_PWY0-1305 GAD_KDA_GLUTAMIC_ACID_DECARBOXYLASE GAD-67_(complex) GAD2 GAD1 GAD-65_(complex)
REACTOME_REACT_150206 Collagen_type_I_fibrils_with_hydroxylysyl-pyrrole_cross-links_(complex) LOXL1 LOXL2 LOXL3 LOXL4 Prolysyl_oxidases_(family) Collagen_type_I_fibrils_with_hydroxylysino-5-ketonorleucine_crosslinks_(complex) Collagen_type_I_fibrils_with_histidino-hydroxylysinoleucine_cross-links_(complex) Collagen_type_1_fibrils_cross-linked_by_dehydro-lysinonorleucine_crosslinks_(complex) Lysyl_oxidases_(family) Collagen_type_I_fibrils_with_lysyl-pyridinoline_cross-links_(complex) Collagen_type_I_fibrils_with_lysino-5-ketonorleucine_cross-links_(complex) Lysyl_oxidase_propeptides_(family) Collagen_type_I_fibrils_with_hydroxylysyl-pyridinoline_cross-links_(complex) Collagen_type_I_fibrils_with_lysyl-pyrrole_cross-links_(complex) LOX Collagen_type_I_fibrils_with_deH-HLNL_cross-links_(complex)
PID_Regulation_of_Commissural_axon_pathfinding_by_Slit_and_Robo Robo1/Robo2_Robo3A.1_(complex) ROBO3 SLIT2 Robo1/_Robo2
PID_mRNA_3__end_processing CF_II_(complex) CLP1 PCF11 CF_I_(complex) mRNA_3prime-end_cleavage_factor_(complex) CPSF7 NUDT21 PAPOLA
PID_no1pathway Ach_R PI3K_(complex) VEGF_R SLC7A1 PRKAR2A AKT1 PLCG1 PRKAR2B PLN CAV1 VEGF/VEGF_R_(complex) PIK3CA RYR2 PDE3A PDE3B CaM/Ca_++_(complex) PKG PIK3R1 TNNI1 bradykinin/Bradykinin_receptor_B2_(complex) NOS3 GNGT1 GNB1 VEGFA PRKAR1A PRKAR1B HSP90AA1 Ach/Ach_R/G-alpha-q/G-beta/G-gamma_(complex) NOS_III/Caveolin-1_(complex) guanylate_cyclase BDKRB2 GNAQ PKA_(complex) KNG1 PDE_III_(complex) PDE2A PRKACG CaM PRKACB PDPK1
REACTOME_REACT_21285 TSC1_TSC2_(complex) TSC1_p-S1387-TSC2_(complex) Rheb_GDP_(complex) TSC1 RHEB TSC2 Rheb_GTP_(complex)
REACTOME_REACT_21402 NTN3 CDH15 MYF5 MYF6 CDO_BOC_Neogenin_Netrin-3_(complex) CTNNB1 MAPK11 MAPK12 Cadherin_Catenin_(complex) ABL1 CDO_BOC_Trans-cadherin_homodimer_catenin_(complex) MYOG Cadherin-catenin_CDO_BOC_Bnip2_CDC42-GTP_(complex) p38_MAPK_alpha/beta/gamma_(family) BOC ABL1_JLP_CDO_complex_(complex) Myod_(family) MEF2B Promyogenic_cadherins_(family) MEF2A alpha/beta_catenin_(family) pp38_alpha/beta/gamma_ABL1_JLP_CDO_complex_(complex) phospho-MEF2_proteins_(family) NEO1 BNIP2 Phospho-p38_MAPK_alpha/beta/gamma_(family) CDH2 CDH4 TCF4 TCF3 SPAG9 Trans-cadherin_homodimers_(complex) TCF12 Myod_phospho-E_heterodimers_(complex) phospho-E_proteins_(family) CDO_BOC_(complex) Cadherin-catenin_JLP_CDO_BOC_Bnip2-Cdc42_(complex) CTNNA1 CTNNA2 MYOD1 MAPK14 phospho-p38_alpha/beta/gamma_MAPK_(family) MyoD_phospho-E_phospho_MEF2_(complex) MEF2C CDC42-GTP_(complex) CDON Cadherin-catenin_CDO_BOC_Bnip2_(complex) MEF2D Netrin-3_Neogenin_(complex) p38_alpha/beta/gamma_ABL1_JLP_CDO_complex_(complex) phospho_p38_phospho_MEF2_(complex) CDC42
PID_TRAIL__signaling TRAIL_receptor-2_TRAIL_complex_(complex) TNFSF10 TNFRSF10B TRAIL_receptor-2_TRAIL_Trimer_(complex) TRAIL_TRAIL_receptor-2_FADD_complex_(complex) CASP8 CASP10 CFLAR TRAIL_TRAIL_receptor-2_Trimer_FADD_Caspase-8_precursor_complex_(complex) TRAIL_TRAIL_receptor-2_Trimer_FADD_Caspase-10_precursor_complex_(complex) FADD
PID_Beta_oxidation_of_hexanoyl_CoA_to_butanoyl_CoA HADH ACADS HADHB enoyl-CoA_hydratase_hexamer_(complex) HADHA short_chain_3-hydroxyacyl-CoA_dehydrogenase_homodimer_(complex) ECHS1 Trifunctional_Protein_(complex) SCAD_acyl-CoA_dehydrogenase_homotetramer_(complex)
REACTOME_REACT_23891 SOS1 Interleukin_receptor_complexes_with_activated_SHC1_SHIP1_(complex) Interleukin_receptor_complexes_with_activated_SHC1_SHIP1_2_(complex) INPP5D SHIP1_2_(family) INPPL1 Interleukin_receptor_complexes_with_activated_SHC1_GRB2_SOS1_(complex) HRAS_GTP_(complex) GAB2 PTPN6 GRB2 GRB2_GAB2_(complex) Interleukin_receptor_complexes_with_activated_SHC1_SHIP_GRB2_(complex) p85-containing_Class_1A_PI3Ks_(complex) HRAS GRB2_SOS1_(complex)
PID_FGFR1b_ligand_binding_and_activation FGFR1b_homodimer_bound_to_FGF_(complex) Activated_FGFR1b_homodimer_bound_to_FGF_(complex) FGFR1b_homodimer_(complex) FGFR_1b_binding_FGFs Activated_FGFR_complexed_with_phosphorylated_FRS2__GRB2_and_CBL_(complex) CBL Phospho-FRS2 GRB2 SDC2
BIOCYC_PWY66-367 BDH1_(complex) HMGCS2 HL_(complex) HADHB acetoacetate_decarboxylase ACAT1 HMGCL mitochondrial_acetyl-CoA_acetyltransferase_(complex)
BIOCYC_PWY-6012 AASDHPPT
REACTOME_REACT_24980 SUMO1 IFNGR1 IFNGR2 IFNGR_complex_with_p-JAK_(complex) IFNG_IFNGR1_p-JAK1_IFNGR2_p-JAK2_(complex) STAT1 IFNG_homodimer_(complex) JAK2 JAK1 IFNG_IFNGR1_JAK1_IFNGR2_JAK2_(complex) p-STAT1_dimer_PIAS_SUMO1_(complex) IFNGR_complex_with_p-JAK2_(complex) IFNG IFNGR1_p-JAK1_(complex) IFNGR2_p-JAK2_(complex) IFNGR2_JAK2_(complex) IFNG_IFNGR1_JAK1_IFNGR2_p-JAK2_SOCS-1/-3_(complex) SOCS1 SOCS3 IFNG_IFNGR1_JAK1_IFNGR2_p-JAK2_(complex) IFNG-activated_factor_(GAF)_(complex) SOCS-1_and_SOCS-3_(family) PIAS1 IFNGR1_JAK1_(complex) IFNGR1_JAK1_INFG2_JAK2_(complex)
PID_Caspase_mediated_cleavage_of_cytoskeletal_proteins CASP6 active_caspase-6_(complex) active_caspase-3_(complex) DBNL CASP3 ADD1 SPTAN1 CASP8 VIM PLEC MAPT Caspase-8_dimer_(complex) GAS2 GSN
REACTOME_REACT_160242 EMD ANKLE2_VRK1/VRK2_(complex) ANKLE2 VRK1 BANF1_homodimer_(complex) EMD/TMPO/LEMD3/LEMD2_Lamin_dimers_BANF1_Chromatin_(complex) VRK1/VRK2_(family) Lamin_dimers_(complex) VRK2 EMD/_TMPO/_LEMD3/_LEMD2_(family) TMPO BANF1 LEMD3 LEMD2
PID_Transcription_coupled_NER__TC_NER_ ERCC8 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex) ERCC1_XPF_complex_(complex) Active_Pol_II_complex_with_repaired_DNA_template_mRNA_hybrid_(complex) Transcription-coupled_(TC)_repair_complex_(complex) GTF2H3 GTF2H2 GTF2H1 GTF2H4 POLR2E POLR2D POLR2G POLR2F POLR2A POLR2C POLR2B POLR2L MNAT1 TCEA1 POLR2I POLR2H POLR2K POLR2J TFIIH_(complex) CDK7 CAK_(complex) CCNH XAB2
PID_Estrogen_biosynthesis CYP19A1
PID_Packaging_of_Eight_RNA_Segments EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 EMBL_AF389119_H1N1_Genomic_RNA_Segment_5 EMBL_AF389120_H1N1_Genomic_RNA_Segment_6 Ribonucleoprotein_(RNP)_Complex_(complex) palmitylated_M2_Tetramer_(complex) Glycosylated__palmitylated_and_folded_HA_trimer_(complex) UniProt_P03485_M EMBL_AF389117_H1N1_Genomic_RNA_Segment_3 UniProt_P03466_NP UniProt_P03431_PB1 UniProt_P03508_NS UniProt_P03428_PB2 EMBL_AF389122_H1N1_Genomic_RNA_Segment_8 UniProt_P03452_HA UniProt_P03433_PA EMBL_AF389115_H1N1_Genomic_RNA_Segment_1 EMBL_AF389118_H1N1_Genomic_RNA_Segment_4 UniProt_P06821_M Gycosylated_NA_Tetramer_(complex) RNP_pre-assembly_complex_(complex) EMBL_AF389116_H1N1_Genomic_RNA_Segment_2 UniProt_P03468_NA
BIOCYC_TRNA-CHARGING-PWY SARS2 FARS2 tRNA<SUP>leu</SUP> L-leucyl-tRNA<SUP>leu</SUP> WARS2 L-PROLYL-TRNA(PRO) EARS2 KARS DARS L-TYROSYL-TRNA(TYR) tRNA<SUP>gly</SUP> L-THREONYL-TRNA(THR) L-seryl-tRNA<SUP>ser</SUP> CARS2 TRNA(TRP) DARS2 L-histidyl-tRNA<SUP>his</SUP> TRNA(LYS) L-valyl-tRNA<SUP>val</SUP> HARS YARS2 IARS2 tRNA<SUP>his</SUP> VARS TRNA(ALA) TARSL2 PARS2 TRNA(TYR) GLYCYL-TRNA(GLY) MARS2 EPRS NARS L-glutamyl-tRNA<SUP>Glu</SUP> YARS NARS2 L-arginyl-tRNA<SUP>arg</SUP> AARS2 RARS2 L-phenylalanyl-tRNA<SUP>phe</SUP> tRNA<SUP>thr</SUP> TRNA(PRO) L-CYSTEINYL-TRNA(CYS) IARS VARS2 tRNA<SUP>val</SUP> TRNA(PHE) CARS tRNA<SUP>asp</SUP> WARS L-glutaminyl-tRNA<SUP>gln</SUP> LYSINE_TRNA_LIGASE_LYSRS L-ALANYL-TRNA(ALA) L-asparaginyl-tRNA<SUP>asn</SUP> QARS tRNA<SUP>ile</SUP> GARS TRNA(CYS) LARS L-METHIONYL-TRNA L-TRYPTOPHANYL-TRNA(TRP) tRNA<SUP>met</SUP> TRNA(GLN) L-ISOLEUCYL-TRNA(ILE) AARS TRNA(ASN) TRNA(SER) tRNA<SUP>Glu</SUP> TRNA(ARG) L-LYSYL-TRNA(LYS) FARSB FARSA L-ASPARTYL-TRNA(ASP) TARS2 MARS TARS SARS HARS2
BIOCYC_PWY-6076 vitamin_D_25-hydroxylase_(complex) CYP2R1 POR CYP27B1
PID_Activation_of_CaMK_IV Calmodulin_CaMK_IV_(complex) Active_Calmodulin_(complex) CALM3 phospho-CaMK_IV_Calmodulin_(complex) CAMK4
PID_ptdinspathway RAB5A RAC1 EEA1 PRKCE ARF1 VAV2 GSK3A PLCG1 GSK3B GTF3A AKT1 BAD PRKCZ GRASP PDPK1 LYN RPS6KB1 PFK BTK
REACTOME_REACT_20580 PARVA_Paxillin_(complex) ACTN1 RSU1 Rsu-1_Pinch1_complex_(complex) ARHGEF6 PARVA_TESK1_(complex) LIMS1 PARVB_alpha_actinin_(complex) PXN PARVB PARVA TESK1 ParvB/Affixin_Alpha-Pix_(complex)
PID_Rho_GTPase_cycle RhoGTPase_GTP_(complex) GDI_proteins RhoGTPase_GDP_(complex) RhoGTPase_GTP_Effectors_complex_(complex) Inactivated_RhoGTPase_GDP_GDI_complex_(complex)
PID_foxm1pathway ONECUT1 MAP2K1 FOXM1 FOXM1B/Cbp/p300_(complex) Cyclin_A-E1/CDK1-2_(complex) FOXM1B/p14ARF_(complex) Cyclin_A-E1 RB1 FOXM1C/SP1_(complex) CHEK2 CDKN2A SP1 FOXM1B/HNF6_(complex) Cbp/p300 CCNB1 CCND1 GSK3A CDK1 CDK2 CDK4 Cyclin_D1/CDK4_(complex) Cyclin_B1/CDK1_(complex)
REACTOME_REACT_13415 NGF mature_NGF_homodimer_p75NTR_(complex) RPS27A IKBKB RIPK2 IRAK1_MYD88_(complex) NGFR NGF_ligand_p75NTR_IRAK1_MYD88_(complex) mature_beta-NGF_homodimer_(complex) IRAK1 PRKCI IKK-beta_homdimer_(complex) TRAF6 NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_IKK-beta_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_aPKCi_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_MYD88_TRAF6_(complex) SQSTM1 NGF_p75NTR_RIP2_(complex) MYD88 MYD88_homodimer_(complex) ubiquitin_(family) NGF_ligand_p75NTR_Phospho-IRAK1_polyubiquitinated_TRAF6_p62_(complex) UBA52 UBB NGF_ligand_p75NTR_p-IRAK1_MYD88_(complex)
PID_SMAC_mediated_apoptotic_response CASP3 SMAC_XIAP_Caspase-3_(complex) XIAP_Caspase-3_(complex) XIAP DIABLO active_caspase-3_(complex)
PID_MRN_complex_relocalizes_to_nuclear_foci gamma-H2AX_NBS1_complex_at_the_site_of_double-strand_break_(complex) H2AFX NBN
PID_Na__dependent_glucose_transporters SLC5A1 SLC5A2 SLC5A9
REACTOME_REACT_150425 Ac-Cohesin_PDS5_Sororin_WAPAL_(complex) AHCTF1 PLK1 CCAN_network_(complex) CENP-(H_I__K)_complex_(complex) p-RAD21-Ac-Cohesin_(complex) KIF2A KIF2C KIF2B BUB1B Ac-Cohesin_PDS5_CDCA5_WAPAL_Sister_Centromeres_Kinetochores_Microtubules_(complex) PDS5A/B_(family) p-RAD21-Ac-Cohesin_PDS5_p-CDCA5_WAPAL_Sister_Centromeres_Kinetochores_Microtubules_(complex) MAPRE1 CENPO CENPN CENPM CENPL CENPK CENPI CENPH CENPF CENPE CDCA5 CENPC RANGAP1 CENPA CENPT PAFAH1B1 CENPQ CENPP NUF2 p-Ac-Cohesin_(complex) PPP2CA PPP2CB Chromosome_passenger_complex_(complex) SPC24 NSL1 SEH1L p-Cohesin_PDS5_WAPAL_(complex) ZWINT PDS5A NUP85 PDS5B p-STAG2_RAD21-Ac-Cohesin_(complex) MIS12 NDC80_complex_(complex) B9D2 XPO1 RZZ_complex_(complex) PDS5A/PDS5B_(family) Ac-Cohesin_Complex_(complex) Mitotic_checkpoint_complex_(complex) p-STAG2_RAD21-Ac-Cohesin_PDS5_p-CDCA5_WAPAL_Sister_Centromeres_Kinetochores_Microtubules_(complex) Microtubule-bound_kinetochore_(complex) SMC1A INCENP Nup107-160_complex_(complex) BUB3 STAG2 SEC13 STAG1 SGOL1 SGOL2 ZWILCH SPDL1 PP2A_(complex) CDC20 SPC25 Acetylated_Cohesin_Complex_(complex) PPP2R5D PPP2R5E PPP2R5A PPP2R5B PPP2R5C NUP133 Ac-Cohesin_PDS5_WAPAL_Centromere_Kinetochore_(complex) DSN1 PPP2R1B NDC80 Kinetochore_(complex) ERCC6L KNTC1 p-SA2_RAD21-Ac-Cohesin_PDS5_p-Sororin_WAPAL_(complex) Sister_Chromosomal_Arms_Ac-Cohesin_PDS5_p-CDCA5_WAPAL_(complex) RANBP2 PP2A-subunit_A_(family) NUP107 ZW10 TAOK1 KMN_network_(complex) WAPAL SMC3 PPP2R1A Ac-Cohesin_PDS5_p-CDCA5_WAPAL_Sister_Centromeres_Kinetochores_Microtubules_(complex) MAD2L1 RPS27 BIRC5 PP2A-catalytic_subunit_C_(family) ITGB3BP BUB1 NDE1 APITD1 MAD1L1 NUP98 NUDC NUP43 SKA1 CLIP1 SKA2 AURKB CENP-O_complex_(complex) CDCA8 Mis12_complex_(complex) p-Cohesin_(complex) CLASP2 CLASP1 RAD21 NUP160 KIF18A PP2A_regulatory_subunit_B56_(family) Ac-Cohesin_PDS5_p-Sororin_WAPAL_(complex) CASC5 NDEL1 RCC2 PPP1CC PMF1 Sister_Centromere_Kinetochore_(complex) NUP37 p-Ac-Cohesin_PDS5_WAPAL_(complex) Sister_Chromosomal_Arms_p-STAG2_RAD21-Ac-Cohesin_PDS5_p-CDCA5_WAPAL_(complex) MLF1IP CKAP5
PID_tcrraspathway ERK1-2/ELK1_(complex) Erk1-2-active MAP3K8 FOS PRKCA RAF1 PRKCB MAP2K1 ERK1-2 ELK1 BRAF RAS_family/GTP_(complex) PTPN7 RAS_family
REACTOME_REACT_11202 ferrous_CYB5A_(complex) CYB5A CYB5A_ferriheme_(complex)
REACTOME_REACT_169325 Nonendonucleolytic_Argonaute_(family) p14-ARF_MDM2_TP53_(complex) MOV10 CDK4-6_(family) RPS27A ENSEMBL_ENST00000579755_CDKN2A ERF INK4A_(family) TNRC6C TNRC6B TNRC6A DP-1_E2F1/2/3_(complex) MDM2 UBIQ_HUMAN_(family) ERF_ETS2_Gene_(complex) TP53_Tetramer_(complex) p16-INK4a/p14-ARF_mRNA__miR-24_Nonendonucleolytic_RISC_(complex) Ub-TP53_(complex) ETS2 ETS1 p-T72-ETS2_ID1_(complex) ETS1/ETS2_(family) TNRC6_(GW182)_(family) CDKN2B CDKN2C CDKN2A UBB CDKN2D SP1 miR-24_Nonendonucleolytic_RISC_(complex) ENSEMBL_ENST00000304494_CDKN2A TP53 Cell_cycle_promoting_E2Fs_(family) Ub-MDM2_(complex) MDM2_TP53_(complex) E2F3 E2F2 E2F1 p-T38-ETS1/_p-T72-ETS2_CDKN2A_Gene_(complex) Cdk4/6_INK4A_complex_(complex) miR-24_Nonendonucleolytic_Minimal_RISC_(complex) p-T38-ETS1/_p-T72-ETS2_(family) ID1 UBA52 CDK4 TFDP1 CDK6 UBC AGO4 AGO1 AGO3 DP1/2__E2F1/2/3__SP1__CDKN2A_Gene_(complex)
PID_NADPH_regeneration IDH1 IDH1_dimer_(complex)
PID_Multifunctional_anion_exchangers SLC26_chloride_transporters Sulfate_transporters Cl-/HCO3-_exchanger_proteins_(SLC26)
PID_Signalling_to_ERKs NGF beta-NGF_homodimer_(complex) Activated_TrkA_receptor_complex_(complex) NTRK1
PID_tubbypathway Ligand GPCR 1-phosphatidylinositol-4-5-bisphosphate_phosphodiesterase G-alpha-q/PLC-beta/TUBBY_(complex) TUB ligand/GPCR(+)_(complex) GNAQ
REACTOME_REACT_822 MAD2L2 UniProt_Q9UID5_hREV3 Pol_zeta_complex_(complex) Pol_zeta_damaged_DNA_template_complex_(complex)
REACTOME_REACT_118713 TEAD2 RUNX2_WWTR1(TAZ)_(complex) WWTR1 TEAD_(family) KAT2B RUNX2 TEAD_WWTR1(TAZ)_(complex) TEAD_YAP1_(complex) TBX5 TEAD3 TBX5_WWTR1_PCAF_(complex) TEAD1 YAP1 TEAD4
REACTOME_REACT_22339 POLR3F RPC7/RPC7-like_(family) GTF3C4 SNAPc_(complex) GTF3C3 GTF3C2 GTF3C1 POLR1C POLR1D POLR3C GTF3C5 POLR3A SNAPC3 POLR3K POLR3H ZNF143 TFIIIB-Type_3_Promoter_Selective_Complex_(complex) Elongating_RNA_Polymerase_III_Transcription_Complex_(complex) RNA_Polymerase_III_TFIIIB_TFIIIC_Type_2_Open_Promoter_Complex_(complex) BDP1 RNA_Polymerase_III_TFIIIB_SNAPc_Type_3_Open_Promoter_Complex_(complex) LZTS1 RNA_Polymerase_III_Holoenzyme_(complex) RNA_polymerase_III_TFIIIB_TFIIIC_TFIIIA_Type_1_Open_Promoter_Complex_(complex) POLR3GL HsRPC4_HsRPC5_(complex) SNAPC2 SNAPC1 POLR2F SNAPC5 SNAPC4 BRF2 POLR2L BRF1 POLR2H POLR2K POLR2E TFIIIB-Type_1_and_2_Promoter_Selective_Complex_(complex) HsRPC6_HsRPC3_HsRPC7_(complex) POLR3G TBP POLR3D GTF3A HsRPC8_HsRPC9_(complex) POLR3E Paused_RNA_Polymerase_III_Transcription_Complex_(complex) TFIIIC_(complex) POLR3B POU2F1
BIOCYC_PWY-6573 ARSB HEXA beta_hexosaminidase_S_(complex) GALNS HYAL4 beta-hexosaminidase_A_(complex) SPAM1 beta-hexosaminidase_B_(complex) HYAL1
PID_Frs2_mediated_activation NGF Active_TrkA_receptor_Frs2_complex_(complex) RAP1/GDP_(complex) Active_TrkA_receptor_Phospho-Frs2_complex_(complex) Activated_TrkA_receptor_complex_(complex) RAP1A FRS2 YWHAB NTRK1 Active_TrkA_receptor_Phospho-Frs2_CrkL_complex_(complex) BRAF CrkL_(SH3_domain) B-Raf_complex_(complex) RAP1/GTP_(complex) beta-NGF_homodimer_(complex) Active_TrkA_receptor_Phospho-Frs2_CrkL_C3G_complex_(complex) C3G Rap1-GTP_B-Raf_complex_(complex)
BIOCYC_PWY-6241 TPO CTSD
PID_erkpathway NGF SRC MKNK2 HRAS MKNK1 MAP2K2 MAP2K1 NGFR RAF1 STAT3 SHC/GRB2/SOS-1_(complex) MAPK3 GRB2 MYC TERT NGF/NGF_R_(complex) SHC1 PTPRR RPS6KA1 RPS6KA5 SOS1 ELK1 EST1 PPP2R5D MAPK1
BIOCYC_PWY-6517 GNPDA2 AMDHD2 GNPDA1 NAGK
PID_Pregnenolone_biosynthesis CYP11A1 STAR cholesterol_STAR_(complex) cholesterol_StAR-related_protein_(complex) AKR1B1 STARD5
BIOCYC_ALANINE-DEG3-PWY GPT
PID_Beta_oxidation_of_pristanoyl_CoA CRAT ACOX2 ACOX3 CROT SCP2 AMACR Acyl-CoA_oxidase_2_(FAD_cofactor)_(complex) Peroxisomal_multifunctional_enzyme_type_2_dimer_(complex) ACOT8 Acyl-CoA_oxidase_3_(FAD_cofactor)_(complex) HSD17B4
REACTOME_REACT_120827 Overexpressed_FGFR1_homodimers_(complex) Overexpressed_FGFR1_TKIs_(complex) Activated_overexpressed_FGFR1_homodimers_(complex)
PID_erbb1_receptor_proximal_pathway Erk1-2-active PTK2 EGFR/EGFR/EGF/EGF/GRB2_(complex) EGFR/EGFR/EGF/EGF/GNAI1/GNAI3/GAB1_(complex) TLN1 EGFR GAB1 PLCG1 WASL GSN GRB2/SOS-1_(complex) RAS_family/GDP_(complex) EGF EGFR/EGFR/EGF/EGF/p46_SHC_(complex) EGFR/EGFR/EGF/EGF/FAK_(complex) EGFR/EGFR/EGF/EGF/p52_SHC/GRB2/SOS1_(complex) STAT3 STAT1 EGFR/EGFR/EGF/EGF/GRB2/SOS1_(complex) RASA1 GNAI3 EGFR/EGFR/EGF/EGF/p52_SHC_(complex) EGFR/EGFR/EGF/EGF/p66_SHC_(complex) GNAI1 JAK1-JAK2 RAS_family/GTP_(complex) SRC PIP5K1C/Talin_(complex) EGFR/EGFR/EGF/EGF/GRB2/PAK1_(complex) SHC1 PI3K_Class_IA_family_(complex) EGFR/EGFR/EGF/EGF/RasGAP_(complex) EGFR/EGFR/EGF/EGF/GNAI1/GNAI3/GAB1/RasGAP_(complex) EGFR/EGFR/EGF/EGF/p46_SHC/GRB2/SOS1_(complex) PTPN1 EGFR/EGFR/EGF/EGF_(complex) PTPN6 NCK1-2 EGFR/EGFR/EGF/EGF/PLCgamma1_(complex) EGFR/EGFR/EGF/EGF/GRB2/GAB1_(complex) SOS1 EGFR/EGFR/EGF/EGF/JAK1-JAK2_(complex) PIP5K1C PTPN11 EGFR/EGFR/EGF/EGF/GRB2/GAB1/RasGAP_(complex) EGFR/EGFR/EGF/EGF/NCK1-2/PAK1_(complex) GRB2 EGFR/EGFR/EGF/EGF/GRB2/N-WASP_(complex) PAK1 RAS_family
PID_ABC_family_proteins_mediated_transport PEX19_ABCD1/ABCD3_(complex) ABCA7-1_ApoA1_complex_(complex) CFTR PEX19 ABCA7 ABCB7 APOA1
BIOCYC_PWY-7224 NME4 NME5 NME6 NME7 NME1 NME2 NME3 AK5 dGK_(complex) GUK1 NME2P1 DGUOK dCK_(complex) nucleoside_diphosphate_kinase_(complex) DCK
REACTOME_REACT_163931 NUP88 AAAS NUP133 NUP85 NUP62 SEH1L NUP98 NUP43 NUP188 NUP214 NUP210 Partially_Disassembled_NPC_(complex) RANBP2 POM121 NUP107 Nup107_Complex_(complex) NUP160 NUP93 TPR Nuclear_Pore_Complex_(p-2S_3T-NUP98)_(complex) NUPL1 NUPL2 NUP50 NUP54 NUP35 p-2S_3T-NUP98_(family) NUP37 NUP153 NUP155 Nup62_Complex_(complex) p-4S_3T-NUP98_(family) NUP205 RAE1
BIOCYC_PWY-6111 CPT1A CPT1C
REACTOME_REACT_75822 NCBP1 NCBP2 Exon_Junction_UPF2_UPF3_Complex_(complex) RPL22 SMG5 SMG7 SMG6 SMG1 SMG9 SMG8 RPS26 SMG1_UPF1_eRF1_eRF3_Complex_Exon_Junction_Complex_on_Translated_mRNA_(complex) MAGOH Translated_mRNA_Complex_with_Premature_Termination_Codon_Preceding_Exon_Junction_(complex) PPP2R2A RPL14 RPL15 RPL17 RPL10 RPL11 RPL12 RPL13 RPL18 RPL19 PPP2CA 40S_ribosomal_complex_(complex) UBA52 RPS15 RPS3 EIF4G1 Cap_Binding_Complex_(CBC)_(complex) RPL37A RPL8 RPL9 RPL6 PABPC1 RPL27A RPL5 SMG1_Phosphorylated_UPF1_EJC_Translated_mRNP_(complex) RPL3 EMBL_V00589 60S_ribosomal_complex_(complex) RPL7A Phosphorylated_UPF1_SMG5_SMG7_SMG6_PP2A_Translated_mRNP_(complex) RPS9 RPS3A GSPT2 RNPS1 UPF1 UPF3_(family) mRNA_Cleaved_by_SMG6_(complex) EIF4A3 RPS12 RPLP2 RPLP1 RPLP0 RPL18A RPL35A RPS15A RPS7 RPS6 RPS5 RPS27A RPS2 UPF2 Magoh-Y14_complex_(complex) RPL41 RPS8 ETF1 RPS4Y1 RBM8A PP2A_(Aalpha_B55alpha_Calpha)_(complex) RPL13A RPL7 RPL4 RPL36A RPS27 RPS24 RPS25 RPS23 RPS20 RPS21 RPS28 RPS29 RPS4X EMBL_J01866 RPSA Core_Exon_Junction_Complex_(Core_EJC)_(complex) mRNA_Complex_with_a_Premature_Termination_Codon_Preceding_an_Exon_Junction_(complex) RPL10A EMBL_M11167 RPS13 PPP2R1A RPS11 RPS10 RPS17 RPS16 RPL23A RPS14 RPS19 RPS18 RPL3L EMBL_X03205 SMG1_SMG8_SMG9_Complex_(complex) RPL29 RPL28 RPL24 RPL27 RPL26 RPL21 RPL23 FAU CASC3 80S_monosome_(complex) RPL26L1 RPL38 RPL39 RPL36 RPL37 RPL34 RPL35 RPL32 GDP_bound_eRF3_(complex) RPL30 RPL31 UPF3B UPF3A
REACTOME_REACT_18423 BiP_Unfolded_Protein_(complex) ATF6 ATF6-alpha_BiP_(complex) HSPA5
PID_Common_Pathway thrombin_cleaved_antithrombin_III_(complex) PROS1 thrombin_antithrombin_III_heparin_(complex) antithrombin_III_heparin_(complex) F13A1 F10 cleaved_antithrombin_III_(complex) SERPINC1 factor_Vi_(complex) thrombin_cleaved_antithrombin_III_heparin_(complex) fibrin_multimer_(complex) fibrin_monomer_(complex) FGG FGA factor_Xa_(complex) Va_Xa_complex_(prothrombinase)_(complex) activated_protein_C_(complex) activated_factor_XIII_(complex) Platelet_Factor_4 Activated_thrombin_(factor_IIa)_(complex) THBD F2 F5 factor_Va_(complex) FGB activated_thrombin_thrombomodulin_(complex) PROC
PID_mtorpathway GHR 40s_Ribosome_subunit MKNK1 AKT1 EIF-4E/EIF-4G/EIF-4A_(complex) TSC2 TSC1 FKBP12/Rapamycin_(complex) TSC1/TSC2_(complex) EIF3A RPS6KB1 RNA_strand 60s_Ribosome_Subunit PI3K_(complex) GH/GH_R_(complex) GH_R/IRS-1_(complex) RPS6(+)/eIF3/40s_Ribosome_subunit_(complex) PIK3R1 40s_Ribosome_subunit/60s_Ribosome_Subunit/RNA_strand_(complex) MTOR PIK3CA EIF4E EIF-4E/EIF4EBP_(complex) EIF-4E/EIF-4G/EIF-4A/eIF-4B/RNA_strand_(complex) EIF4B GH1 RPS6 EIF4G1 IRS1 PTEN PDK2 EIF4EBP1 FKBP1A PPP2R5D RHEB EIF4A1
PID__5_Phosphoribose_1_diphosphate_biosynthesis phosphoribosyl_pyrophosphate_synthetase_1_holoenzyme_(complex) PRPS1
BIOCYC_PWY66-387 2-HPCL_(complex) ALDH3A2 ACSL1 HACL1 PHYH SLC27A2
BIOCYC_PWY-66 TSTA3 GMDS
REACTOME_REACT_160243 FBXW7_SKP1_CUL1_RBX1_(complex) p-NICD1_PEST_domain_mutants_(family) NEXT1_PEST_domain_mutants_(family) Ub-DLL/JAG_NOTCH1_fragment_(complex) RPS27A NOTCH1_PEST_Domain_Mutants_Coactivator_Complex_HEY_Genes_(complex) KAT2A NICD1_PEST_domain_mutants_RBPJ_SNW1_(complex) NOTCH1_PEST_Domain_Mutants_Coactivator_Complex_(complex) JAG1_NOTCH1_PEST_Domain_Mutants_(complex) RBPJ_SNW1_(complex) HEYL MAML2 MAML3 DLL/JAG_NOTCH1_PEST_Domain_Mutants_(complex) MAML1 NOTCH_Ligand_(family) RBPJ NOTCH1_PEST_Domain_Mutants_Coactivator_Complex_CDK8_CCNC_(complex) UBA52 NOTCH1_PEST_Domain_Mutants_Coactivator_Complex_MYC_Gene_(complex) JAG2 MYC JAG1 CUL1 FBXW7 CDK8_CCNC_(complex) Ub-DLL/JAG_NOTCH1_PEST_Domain_Mutants_(complex) NOTCH1_PEST_Domain_Mutants_Coactivator_Complex_HES5_Gene_(complex) KAT2B_(family) UBC DLL1 NOTCH1_PEST_Domain_Mutants_Coactivator_Complex_HES1_Gene_(complex) DLL4 NOTCH1_fragment_DLL/JAG_(complex) FBXW7alpha/gamma_(family) MAML_(family) DLL1_NOTCH1_PEST_Domain_Mutants_(complex) EP300 HEY2 HEY1 DLL4_NOTCH1_PEST_Domain_Mutants_(complex) SNW1 RBX1 ubiquitin_(family) NOTCH1_fragment_(complex) NICD1_PEST_Domain_Mutants_(family) NOTCH1 JAG2_NOTCH1_PEST_Domain_Mutants_(complex) SKP1 MAMLD1 NOTCH1_PEST_domain_mutants_(complex) UBB CCNC CDK8 HES1 HEY_(family) HES5 CREBBP
PID_glypicanpathway GPC1 GPC2 GPC3
PID_tertpathway HDAC1 SP1 SP1/HDAC_(complex) TP53 p53/SP1_(complex)
PID_Collagen_adhesion_via_alpha_2_beta_1_glycoprotein ITGB1 ITGA2 Alpha_2_Beta_1_Integrin_(complex) COL1A2 Alpha_2_Beta_1_Integrin___Collagen_IV__Mg++_complex_(complex) Collagen_I_(alpha_1__alpha_1__alpha_2)_(complex) COL1A1
REACTOME_REACT_8 REV1 REV1_damaged_DNA_template_complex_(complex) REV1_lesioned_DNA_template_with_misinserted_bases_(complex)
PID_RNA_Polymerase_III_Transcription NFIC NFIB NFIA POLR3F RNA_Polymerase_III_Holoenzyme_(complex) SSB Paused_RNA_Polymerase_III_Transcription_Complex_(complex) POLR2E POLR3D Elongating_RNA_Polymerase_III_Transcription_Complex_(complex) POLR3B POLR3H POLR2F POLR3A POLR2L POLR3E NFIX POLR2H POLR2K LZTS1
REACTOME_REACT_6244 NELFB P-TEFb_complex_(complex) TCEB1 NELFA NELFE TCEB3 CCNT1 Elongin_B_C_complex_(complex) CCNT2 RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) SUPT5H SSRP1 POLR2K CDK9 TCEB2 FACT_complex_(complex) ELL SUPT16H Elongin_Complex_(complex) TCEA1 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L CTDP1 POLR2I POLR2H HIV-1_processive_elongation_complex_(complex) POLR2J GTF2F1 NELFCD GTF2F2 HIV-1_paused_processive_elongation_complex_(complex) NELF_complex_(complex) SUPT4H1 DSIF_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex)
BIOCYC_GLNSYN-PWY GLUL GLUTAMATE_AMMONIA_LIGASE GS_(complex)
PID_il6pathway CEBPB SHC/GRB2/SOS-1_(complex) STAT3 LRPPRC SOS1 HRAS NF-IL-6/NF-IL-6_(complex) IL6R IL-6/IL-6/IL-6R-alpha/IL-6R-alpha/GP130/GP130_(complex) IL6 GRB2 JAKs STAT3/STAT3_(complex) IL-6/IL-6/IL-6R-alpha/IL-6R-alpha/GP130/GP130/JAKs_(complex) STAT3/STAT3/STAT3/STAT3_(complex) PTPN11 SHP-2/GRB2/SOS-1_(complex) SHC1
BIOCYC_PWY66-394 LTA4H PTGS2 ALOX5
REACTOME_REACT_25060 TF holoTF_(complex)
REACTOME_REACT_12582 CD3_epsilon__CD3_gamma_with_phosphorylated_ITAM_(complex) Antigen-bearing_MHC_Class_II__TCR_with_phosphorylated_ITAMs_CD4_(complex) TCRA PAG1 CD3_epsilon_delta_(complex) CD4 CD247 TCR_chain_beta_(family) TCR_chain_alpha_(family) HLA-DRA CD3_zeta_dimer_with_phosphorylated_ITAMs_(complex) TRBC1 CD3_epsilon__CD3_delta_with_phosphorylated_ITAMs_(complex) MHC_class_II_alpha/beta_dimer_(complex) HLA-DQB1 HLA-DQB2 T-cell_receptor_(complex) TVA1_HUMAN HLA-DPB1 TCRB CSK HLA-DRB3 HLA-DRB1 MHC_Class_II_bearing_antigen_peptide_(complex) CD3_epsilon_gamma_(complex) HLA-DRB4 HLA-DRB5 TRBV12-3 Antigen-bearing_MHC_Class_II___TCR_complex_CD4_p-Lck(Y505)_(complex) Antigen-bearing_MHC_Class_II___TCR_complex_CD4_Lck_(complex) LCK TVA3_HUMAN TRAC Antigen-bearing_MHC_Class_II__TCR_complex_CD4__Lck_phosphorylated_at_Tyr394_(complex) HLA_II_beta_chain_(family) Csk_p-PAG_(complex) CD3E T-cell_receptor_complex_(complex) T-cell_receptor_complex_with_phosphorylated_ITAMs_(complex) HLA_II_alpha_chain_(family) HLA-DPA1 CD3D HLA-DQA1 HLA-DQA2 CD3G
PID_tall1pathway TNFSF13 TRAF2 TRAF3 APRIL/TACI/TRAF6/TRAF5/TRAF2_(complex) TRAF6 TNFRSF17 BAFF/BCMA/TRAF6/TRAF5/TRAF3_(complex) TRAF5 APRIL/BCMA/TRAF6/TRAF5/TRAF3_(complex) BAFF/TACI/TRAF6/TRAF5/TRAF2_(complex) TNFRSF13B TNFSF13B
PID_Thyroxine_biosynthesis TPO Iodotyrosine_dehalogenase DEHAL1_FMN_(complex) SLC5A5
PID_Plus_strand_DNA_synthesis minus_sssDNA_primer_for_minus_strand_DNA_extension_(complex) Reverse_Transcriptase_heterodimer_(complex) VIF RTC_with_duplex_DNA_containing_discontinuous_plus_strand_flap_(complex) EMBL_AF033819_EMBL_AF033819 p51_subunit_of_RT p6_protein RTC_without_viral_RNA_template_(complex) Rev RTC_with_extending_second-strand_DNA_(complex) PPIA p66_subunit_of_RT Vpu_protein RTC_with_extending_minus_strand_DNA_(complex) Vpr_protein Integrase RTC_with_annealed_complementary_PBS_seqments_in_+sssDNA_and_-strand_DNA_(complex) Matrix
PID_Activation_of_Pro_Caspase_8 TRAF2 TNFSF10 TRAIL_receptor-2_TRAIL_Trimer_(complex) TRAIL_TRAIL_receptor-2_FADD_complex_(complex) TRAIL_receptor-2_TRAIL_complex_(complex) TRADD RIPK1 TNFRSF10B CASP8 FADD TRAF2_TRADD_RIP1_Complex_(complex) TRAF2_TRADD_RIP1_FADD_(complex)
PANTHER_P05734 synaptic_vesicle_fusion_complex_(complex) SNAP25 Synaptobrevin Munc13 Syntaxin_1/2 RIM1alpha/2alpha Munc18 Synaptotagmin Rab3A SNARE_Complex_(complex)
Pathway_a13ba6a482692bda0eed390243d56f81.owl CYP2C9 CYP1A1 CYP2D6 CYP2A13 CYP2B6 CYP2C19 CYP2A6 CYP3A4 CYP3A5 CYP2C18
REACTOME_REACT_11152 RAET1E NKG2D_ligand_(family) AMICA1 CD34 HV305_HUMAN B2M CD226 Lymphoid-expressed_Fc-gamma_receptors_(family) MICB Integrin_alpha4beta1_(VLA-4)_(complex) HV303_HUMAN KIR2DS1_complexed_with_DAP12_(complex) TCR_interacting_with_antigen-bearing_MHC_Class_I_(complex) HLA-C_Cw3_(group_1)_(complex) TYROBP Complex_of_CD19__CD81__CD225_and_CD21_(complex) Ligand_interacting_with_NKG2D_(complex) HV205_HUMAN HV206_HUMAN CDH1 HLA-E_interacting_with_KLRC1_KLRD1_(complex) IFITM1 Ig_Heavy_Chain_V_Region_(family) CXADR CRTAM_bound_to_NECL2_(complex) Antigen-bound_antibody_bound_to_lymphoid_Fc_gamma_receptors_(complex) KIR2DS2_complexed_with_DAP12_(complex) CD8_(complex) HV107_HUMAN HV314_HUMAN T-cell_receptor_complex_(complex) MHC_Class_I_(family) TCR_chain_alpha_(family) HV313_HUMAN ULBP3 HV310_HUMAN PVR HV308_HUMAN CD3E Integrin_alphaLbeta2_(LFA-1)_(complex) CD3G KLRC1 CD40_complexed_with_CD40L_(complex) HV304_HUMAN HLA-B HLA-A CD3_epsilon_delta_(complex) ITGA4 HLA-F HV209_HUMAN HCST CD200 Ig_Antibody_Light_Chain_(complex) HV319_HUMAN HLA-C_group_1_interacting_with_KIR2DS2_(complex) LILR-interacting_MHC_Class_I_molecules_(complex) LILRB4 LILRB3 LILRB2 LILRB1 KIR2DS2 KIR2DS1 XXbac-BPG181B23.1-003 HV203_HUMAN PVRL2 HV316_HUMAN MADCAM1 CD226_bound_to_Nectin_2_(complex) HV105_HUMAN HV302_HUMAN CXADR_bound_to_JAML_(complex) HV306_HUMAN CD40 HV321_HUMAN HV102_HUMAN KIR3DL1 KIR3DL2 UniProt_A2KUC3_IGHV KLRG1 HV208_HUMAN CD3_epsilon_gamma_(complex) T-cell_receptor_complex_with_CD8_(complex) CD96 CD3D HLA_Bw4_interacting_with_KIR3DL1_(complex) HLA-A3_(complex) KIR2DL3 KIR2DL2 HV315_HUMAN ITGAL HV207_HUMAN Beta-2-microglobulin_class_I_MHC_heavy_chain_Complex_(complex) HV312_HUMAN ICAM_1-4_(family) CD19 CD40LG LILRB5 HV201_HUMAN Integrin_alpha4beta7_(complex) NKG2D_complexed_with_DAP10_(complex) HV106_HUMAN Integrin_alpha4beta7_MADCAM1_(complex) HLA-C_group_2_interacting_with_KIR2DL1_(complex) HV202_HUMAN HLA-Bw4_(complex) TRBC1 HLA-C_group_2_interacting_with_KIR2DS1_(complex) CD81 ULBP1 MHC_Class_I_interacting_with_CD160_(complex) HLA-E_(complex) HLA-C ICAM4 ICAM3 ICAM2 HV311_HUMAN C3 CD200R1 Antigen-bound_Ig_G_Antibody_(complex) ICAM1 MHC_Class_I_molecules_interacting_with_CD160_(complex) CD96_PVR_(complex) HV317_HUMAN LFA-1_ICAM_1-4_(complex) Complex_of_CD19__CD81__CD225_and_CD21_with_C3d-bound_Antigen_(complex) VCAM1 T-cell_receptor_(complex) CD8A CD8B HLA-C_Cw4_(group_2)_(complex) CRTAM L-selectin_ligands_(family) TVA1_HUMAN CD200_bound_to_CD200R_(complex) HV101_HUMAN HV307_HUMAN HLA-G_interacting_with_KIR2DL4_(complex) GLYCAM1 HLA-G_(complex) LILR_set_(family) C3d_complexed_with_antigen_(complex) HLA-A3_interacting_with_KIR3DL2_(complex) MHC_Class_I_interacting_with_LILRs_(complex) KLRD1 TCRA TCRB FCGR3A CD247 TCR_chain_beta_(family) HV104_HUMAN CD226_PVR_(complex) HV309_HUMAN E-cadherin_bound_to_KLRG1_(complex) integrin_alpha4beta1_VCAM1_(complex) KIR2DL1 HLA-C_group-I-interacting_KIRs_(family) HV320_HUMAN L-selectin_interacting_with_known_ligands_(complex) TRBV12-3 HV204_HUMAN HV318_HUMAN ITGB1 ITGB2 ITGB7 KIR2DL4 FCGR2B HV301_HUMAN SELL TVA3_HUMAN KLRK1 CD160 HLA-C_group_1_interacting_with_KIR2DL2/3_(complex) UniProt_O15181_cd21 Antigen_peptide_bound_class_I_MHC_(complex) UniProt_Q6PIL0_IGHV7-81 LILRA1
PID_Netrin_1_signaling pEzrin_PIP2_(complex) Neogenin_RGD_(complex) RGD Ezrin_PIP2_(complex) Robo_Slit_(complex) PIKE-L_UNC5B_(complex) Netrin_DCC_oligomer_(complex) SIAH1_bound_to_DCC_Netrin-1_(complex) DCC/UNC5A DCC/Neogenin DCC NEO1 Slit_[1-3] Myosin-X_DCC/Neogenin_(complex) SIAH2_bound_to_DCC_Netrin-1_(complex) SIAH1 SIAH2 Netrin-1_Neogenin_(complex) UNC5B DCC_Ezrin_complex_(complex) AGAP2 DCC_Netrin-1_(complex) PRKCQ ROBO1 NTN1 NTN4 DCC_Robo_Slit_(complex) EZR DCC&UNC5A_Netrin-4_(complex) MYO10
PID_agpcrpathway NT_(neurotransmitter) PRKAR1B NT/GPCR_(cytoplasm)_(complex) NT/GPCR_(complex) PKC GRK4 NT_transporter GNB1 GPCR/g-alpha-s/g-beta/g-gamma_(complex) g-alpha/g-beta/g-gamma_(complex) PRKAR2A PKA_(complex) GPCR PRKACB PRKAR1A GNGT1 ARRB1 PRKAR2B G-alpha-S PRKACG NT/GPCR/g-alpha/g-beta/g-gamma_(complex)
PID_dsppathway MAPK DSP
PID_Polyamines_are_oxidized_to_amines__aldehydes_and_H2O2_by_PAOs PAOX PAO-FAD_complex_(complex) Spermidine_Oxidase_(SMOX)
PID_Na__Cl__dependent_neurotransmitter_transporters SLC6A3 SLC6A2 SLC6A20 SLC6A7 SLC6A6 GLYT SLC6A19 VMAT1/2 SLC6A_GABA_transporters SLC6A18 SLC22A2 SLC6A12 SLC6A15 SLC6A14
PID_Apoptotic_cleavage_of_cell_adhesion__proteins OCLN TJP2 TJP1 CASP3 active_caspase-3_(complex) DSP CTNNB1 DSG2 PKP1 CDH1 DSG3 DSG1
REACTOME_REACT_15309 STX1A SNAP25 VAMP2 Docked_acetylcholine_loaded_Synaptic_Vesicle_(complex) Rab3-RIM_complex_(complex) Acetylcholine_Loaded_Synaptic_Vesicle_(complex) STXBP1 CPLX1 RAB3A SYT1 SLC18A3 RIMS1
PID_egfpathway PI3K_(complex) HRAS EGFR PLCG1 ELK1 MAP2K4 EGF STAT3 STAT1 PIK3CA SHC/GRB2/SOS-1_(complex) MAP3K1 PKC EGF/EGF-R_(complex) PIK3R1 JAK1 MAPK8 SHC1 STAT1/STAT3_(complex) RASA1 SOS1 MAP2K1 GRB2 STAT3/STAT3_(complex)
PID_SOS_mediated_signalling SOS1 GRB2_SOS_IRS-P_(complex) p21_RAS p21_RAS_GTP_(complex) GRB2 phospho-IRS-1/2 GRB2_SOS1_(complex)
PID_Viral_Messenger_RNA_Synthesis RNA_Polymerase_II_(phosphorylated)_TFIIF_capped_pre-mRNA_(complex) UniProt_P03433_PA Viral_RNA_dependent_RNA_polymerase_(complex) Initiated_vRNA_Transcription_Complex_(complex) vRNA_(Genomic)_NP_Complex_(complex) NS2_mRNA EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 EMBL_J02150_NS1_mRNA vRNA_polymerase_host_mRNA_complex_(complex) UniProt_P03466_NP UniProt_P03431_PB1 Genomic_RNA_Segment_3 UniProt_P03428_PB2 RNA_Polymerase_II_holoenzyme_complex_(phosphorylated)_(complex) POLR2E POLR2D POLR2G POLR2F TFIIF_(complex) POLR2C POLR2B POLR2L POLR2I POLR2H POLR2K POLR2J GTF2F1 GTF2F2 Elongated_vRNA-mRNA_Complex_(complex) RNA_polymerase_II_(phosphorylated)_TFIIF_complex_(complex) EMBL_J02150_NS2_mRNA
BIOCYC_PWY66-399 PCK1 MDH1 BPGM G6PC3 G6PC2 fructose-bisphosphate_aldolase_A_(complex) TPI1 PGAM2 FBP1 FBP2 PGAM1 fructose-bisphosphate_aldolase_C_(complex) PGAM-M_(complex) MSE_(complex) PC TIM_(complex) PGK2 PGK1 fructose-bisphosphate_aldolase_B_(complex) GPI GAPDH_(complex) GAPDHS MBP-1_(complex) ENO1 ENO3 ALDOA ALDOB NSE_(complex) G6PC cytosolic_malate_dehydrogenase_(complex) MDH2
PID_PERK_regulated_gene_expression Proteins_Upregulated_by_ATF4 HSPA5 EIF2AK3 PERK_Homodimer_(complex) ASNS BiP_unfolded_protein_complex_(complex) ATF4 EIF2S1 ATF3
PID_Early_Phase_of_HIV_Life_Cycle linear_duplex_viral_DNA_(complex) Matrix p51_subunit_of_RT Reverse_Transcriptase_heterodimer_(complex) Rev FEN1 RTC_with_tRNA_primer_RNA_template_(complex) Vpr_protein EMBL_AF033819_EMBL_AF033819 p66_subunit_of_RT LIG1 RNA_template_tRNA_primer_(complex) RTC_with_integration_competent_viral_DNA_(complex) Nucleocapsid Vpu_protein Integrase VIF Protease p6_protein HIV-1_RNA_homodimer_(complex) Viral_core_surrounded_by_Matrix_layer_(complex) PPIA
PID_Integration_of_energy_metabolism SNAP25 VAMP2 Core_SNARE_Complex_(complex) 6-phosphofructo-2-kinase/fructose-2_6-biphosphatase_1_homodimer_(complex) PP2A-ABdeltaC_complex_(complex) MLXIPL Inactive_PP2A-ABdeltaC_complex_(complex) PFKFB1 Syntaxin_1A phosphoPFKFB1_dimer_(complex) PKA_catalytic_subunit
PID_il1pathway IL1_beta_fragment/IL1R1/IL1RAP/MYD88/IRAK4/IRAK/TOLLIP_(complex) ERC1 IRAK/TRAF6/MEKK3_(complex) IL1_alpha/IL1R2_(complex) MAP3K7 IKBKB IL1RN/IL1R1_(complex) IKBKG IL1RN/IL1R2_(complex) IL1A IL1B IL1_alpha/IL1R1/IL1RAP/MYD88_(complex) IL1R1 IL1_alpha/IL1R1/IL1RAP_(complex) IL1_beta_fragment/IL1R1/IL1RAP/PI3K_(complex) TICAM2 MAP3K3 UBC13/UEV1A_(complex) JUN IL1_beta_fragment/IL1R1/IL1RAP/MYD88_(complex) IL1R2 IL1_beta_fragment/IL1R1/IL1RAP/MYD88/IRAK4_(complex) PIK3R1 IL1_beta_fragment/IL1R1/IL1RAP_(complex) IKK_complex/ELKS_(complex) IRAK1 IRAK4 IRAK/TRAF6/TAK1/TAB1/TAB2_(complex) TRAF6 IL1RN NF_kappa_B1_p50/RelA_(complex) CHUK MYD88s SQSTM1 PIK3CA IRAK/TRAF6/p62/Atypical_PKCs_(complex) IL1RAP UBE2V1 MAPK8 IL1_alpha/IL1R1/IL1RAP/MYD88/IRAK4/TOLLIP_(complex) Caspase_1_(cleaved) Atypical_PKCs MYD88 TOLLIP UBE2N IL1_beta_fragment/IL1R1/IL1RAP/MYD88s_(complex) TAB1 NFKB1 IL1_alpha/IL1R1/IL1RAP/MYD88/IRAK4_(complex) RELA IRAK/TRAF6_(complex) IL1_beta_fragment/IL1R1/IL1RAP/TICAM2/IRAK4_(complex) IRAK3 IL1_alpha/IL1R1/IL1RAP/MYD88/IRAK4/IRAK/TOLLIP_(complex) Pellinos TRAF6/TAK1/TAB1/TAB2_(complex) TAB2 MAP2K6
REACTOME_REACT_6326 EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 EMBL_AF389119_H1N1_Genomic_RNA_Segment_5 EMBL_AF389120_H1N1_Genomic_RNA_Segment_6 Ribonucleoprotein_(RNP)_Complex_(complex) Influenza_A_Viral_Envelope_(complex) palmitylated_M2_Tetramer_(complex) UniProt_P03485_M EMBL_AF389117_H1N1_Genomic_RNA_Segment_3 UniProt_P03466_NP UniProt_P03431_PB1 UniProt_P03508_NS UniProt_P03428_PB2 EMBL_AF389122_H1N1_Genomic_RNA_Segment_8 Influenza_A_Viral_Particle_(complex) UniProt_P03452_HA UniProt_P03433_PA EMBL_AF389115_H1N1_Genomic_RNA_Segment_1 EMBL_AF389118_H1N1_Genomic_RNA_Segment_4 UniProt_P06821_M Gycosylated_NA_Tetramer_(complex) EMBL_AF389116_H1N1_Genomic_RNA_Segment_2 UniProt_P03468_NA Cleaved_Trimeric_palmitylated_HA_(complex)
PID_betacatenin_nuc_pathway HDAC1 TCF1E/TLE2_(complex) TCF4E/beta_catenin/p300_(complex) BRG1 MYF5 CDX1 TLE2 TCF7 beta_catenin/APC/CtBP_(complex) MDFIC HDAC1/PITX2_(complex) TCF3/beta_catenin_(complex) TNIK LEF1/beta_catenin/PITX2_(complex) TLE2/LEF1_(complex) beta_catenin/myogenin_(complex) PITX2 MYOG TCF4/beta_catenin/HBP1_(complex) XPO1 beta_catenin/ICAT_(complex) TCF1E/beta_catenin_(complex) RUVBL2 CHD8 TCF4E/TLE4_(complex) JUN 14-3-3_family/chibby/beta_catenin_(complex) TCF4/beta_catenin/JUN/DVL3_(complex) DVL3 MED12 14-3-3_family beta_catenin/IMFA_(complex) TLE4 TERT beta_catenin/TBL1/TBLR1_(complex) CUL1 TCF4 TCF4/beta_catenin/Cbp_(complex) TCF4/beta_catenin/TBLR1/TBL1_(complex) LEF1/beta_catenin/CDX1_(complex) TCF4/beta_catenin/TNIK_(complex) IMFA/MYF5_(complex) KLF4 TRRAP TCF4/beta_catenin/KLF4_(complex) beta_catenin/MED12_(complex) TCF4/HDAC1-HDAC2_(complex) TCF1/beta_catenin_(complex) TCF4E/beta_catenin/BCL9_(complex) APC TCF4/beta_catenin_(complex) LEF1 EP300 TCF4/beta_catenin/TIP49B_(complex) CBY1 TBL1XR1 CTNNB1 ADCY7 TBL1X CK2_(complex) beta_catenin/APC_(complex) TCF4/beta_catenin/TRRAP/SCF_(complex) BTRC LEF1/beta_catenin_(complex) TCF7L2 HBP1 beta_catenin/duplin_(complex) SKP1 TCF3/beta_catenin/TERT/BRG1_(complex) BCL9 CTNNBIP1 CTBP1 beta_catenin/PITX2_(complex) TCF7L1 TCF4/beta_catenin/p300_(complex) TCF4E/beta_catenin_(complex) HDAC1-HDAC2
REACTOME_REACT_1391 MAP2K2 MAPK1 phospho-ERK-2_dimer_(complex) MEK2_ERK-2_(complex) phospho-ERK-2_MEK2_(complex)
PID_plcepathway RAP2B AC Forskolin/B2AR_(complex) PRKAR1A Prostaglandin_E1/PGE1R_(complex) RAPGEF3 PRKACG PTGER1 PRKAR2A PKA_(complex) ADRB2 PRKAR2B PLCE1 G-alpha-S/AC_(complex) PRKAR1B PRKACB G-alpha-S Epinephrine/B2AR_(complex)
PID_Activation_of_PUMA_and_translocation_to_mitochondria TFDP1 BBC3 DP-1_E2F1_complex_(complex) E2F1
PID_Pyrimidine_biosynthesis carbamoyl-phosphate_synthetase_2__aspartate_transcarbamylase__and_dihydroorotase_hexamer_(complex) UMPS TS_dimer_(complex) DCTD_hexamer_(complex) DHODH DCTD dihydroorotate_dehydrogenase_holoenzyme_(complex) TYMS UMPS_dimer_(complex) DUT_trimer_(complex) DUT CAD
PID_Transport_of_connexons_to_the_plasma_membrane Connexon_26_(complex) GJB2
PID_Regulation_of_thyroid_hormone_activity DIO3
PANTHER_P06211 IGF2 PUT_(complex) NEJ pro_ligand_dimer_(complex) Full-length_BMP_orthologous_ligand ligand/phosphoTGFbetaR_I_TGFbetaR_II_(complex) BABO_(complex) STAT Co-Smad_phospho_R-Smad_(complex) __(complex) BCHE LV107_HUMAN SHN/MED/_phosphoMAD_(complex) TGFbetaR_II ligand_TGFbetaR_I_TGFbetaR_II_(complex) KV206_HUMAN ligand/phosphoTGFbetaR_I_TGFbetaR_II_phosphoR-Smad_(complex) ligand/phosphoTGFbetaR_I_TGFbetaR_II_R-Smad_(complex) SOG FYN ALP23B_full_length proDPP_(complex) SAX TSG SOG/TSG_DPP_dimer_(complex) phospho-ubiq_R-Smad/Smurf_(complex) BMP_ligand_TGFbetaR_II_(complex) R-Smad BMP_orthologous_ligand_(complex) phosphoR-Smad_Smurf_(complex) MAD_(complex) CREB_(complex) WIT_(complex) activinbeta_full_length DPP_(complex) NEJ/MED/_phosphoMAD_(complex) Smurf TKV_(complex) SHN ligand/phosphoTGFbetaR_I_TGFbetaR_II_I-Smad_(complex) TL_(complex) TRIF_(complex) SPZ_(complex) BMP_ligand_TGFbetaR_I_(complex) TGFbetaR_I_(complex) SMOX_(complex) I-Smad CHRNA4_(complex) Co-Smad
REACTOME_REACT_12507 Sec23p_Sec24p_Complex_(complex) Sar1b_GDP_Complex_(complex) SEC23A Sar1b_Sec23p_Sec24p_Sec13p_Sec31p_Complex_(complex) Sar1b_GTP_Sec23p_Sec24p_Sec13p_Sec31p_Complex_(complex) SEC13 Sar1b_GTP_Sec23p_Sec24p_(complex) SEC24D Sar1b_GTP_Complex_(complex) SEC24A SEC24C SEC24B Sec24_(family) SAR1B Sec13p_Sec31p_Complex_(complex) SEC31A
PID_Highly_sodium_permeable_acetylcholine_nicotinic_receptors O-Acetylcholine_bound_to_Acetylcholine_receptor_(complex)
REACTOME_REACT_22292 CHL1_alpha1beta1/alpha2beta1_integrins_(complex) HSPA8 CHL1_CNTN6_(complex) ANK1 CNTN6 CHL1_Ankyrin-G_(complex) CHL1 CHL1_HSP7C_(complex) Integrin_alpha1beta1__alpha2beta1__alpha10beta1_(complex) NRP1 CHL1_NRP1_(complex)
PID_Leukotriene_synthesis Gamma-glutamyltransferase_5_(complex) ALOX5_(iron__calcium_cofactors)_(complex) ALOX5 LTC4_synthase_homodimer_(complex) ABCC1 MAPKAPK2 LTC4S GGT5 LTA4H Dipeptidase_homodimer_(zinc_cofactor)_(complex) DPEP2 LTA4_hydrolase_(Zinc_cofactor)_(complex)
PID_Synthesis_of_bile_acids_and_bile_salts_via_7alpha_hydroxycholesterol SLC27A5 ACOX2 BAAT SCP2 AKR1D1 Acyl-CoA_oxidase_2_(FAD_cofactor)_(complex) CYP27A1 AMACR ABCB11 HSD3B7 ACOT8 CYP8B1 AKR1C4 Peroxisomal_multifunctional_enzyme_type_2_dimer_(complex) CYP7A1 HSD17B4 SLC27A2
PID_wnvpathway CASP6 APAF-1/Caspase_9_(complex) CASP3 CASP7 WNV_RNA CYCS CASP9 TIAL1 TIA1 APAF1
PID_Miscellaneous_substrates CYP2S1 CYP3A43 CYP4F11 CYP2W1 CYP2U1
PID_Apoptotic_execution__phase CASP3 CASP8 STK24 DNM1L Caspase-8_dimer_(complex) active_caspase-3_(complex)
REACTOME_REACT_25091 unfolded_protein_(GlcNAc)2_(Man)8c_(complex) unfolded_protein_(Glc)1_(GlcNAc)2_(Man)9_(Asn)1_(complex) unfolded_protein_(GlcNAc)2_(Man)8b_(complex) unfolded_protein_(Glc)1_(GlcNAc)2_(Man)9_(complex) unfolded_protein_(GlcNAc)2_(Man)7aa_(complex) (un)folded_protein_(GlcNAc)2_(Man)9_(complex) unfolded_protein_(GlcNAc)2_(Man)8a_(complex)
REACTOME_REACT_11103 AP-1_Complex_(complex) AP1S2 AP1M2 AP1G1 HLA-A AP1M1 Nef_class_I_MHC_complex_Ap-1_PACS-1_Complex_(complex) B2M AP-1_mu_(family) AP1S1 AP-1_sigma_(family) AP1S3 Nef_class_I_MHC_complex_AP-1_PACS-1_Complex_(complex) AP1B1 UniProt_P04601_nef class_I_MHC_complex_(complex) PACS1 Nef_class_I_MHC_complex_(complex)
BIOCYC_GLUTDEG-PWY GOT2 GOT1 GOT1L1 TRANSAMINASE_A_GLUTAMATE_OXALOACETATE_TRANSAMINASE SIMILAR_TO_FH_(FUMARATE_HYDRATASE)
PID_Regulation_of_beta_cell_development NEUROD1 ONECUT3 ONECUT1 NKX2-2 NEUROG3 PDX1 NKX6-1
REACTOME_REACT_6818 monoubiquitinated_N-myristoyl_GAG_(P04591)_protein_(complex) ubiquitin_(family) RPS27A UniProt_P04591_gag UBA52 UBC
PID_igf1pathway PI3K_(complex) HRAS MAP2K1 RAF1 PIK3CA SHC/GRB2/SOS-1_(complex) JUN MAPK3 ELK1 PIK3R1 MAPK8 AP-1_(complex) IGF1R IGF1 SRF SHC1 FOS RASA1 CSNK2A1 ELK-1/SRF/SRF_(complex) SOS1 PTPN11 IRS1 IGF-1/IGF-1/IGF-1R-alpha/IGF-1R-alpha/IGF-1R-beta/IGF-1R-beta_(complex) GRB2 SHP-2/GRB2/SOS-1_(complex)
PID_parkinpathway UbC6/7/ubiquitin_(complex) UbC6/7 Substrate UbC6/7/Parkin/PAEL-R/ubiquitin_(complex) UbCH7/8/Parkin/Substrate/ubiquitin_(complex) SUMO1 PAEL-R/ubiquitin_(complex) PARK2 UbCH7/8 SUMO-1/ubiquitin_(complex) UbCH7/8/ubiquitin_(complex) GPR37 ubiquitin
PID_LPS_transferred_from_LBP_carrier_to_CD14 CD14 LPS_complexed_with_secreted_CD14_(complex) LPS_complexed_with_GPI-anchored_CD14_(complex)
PID_Activation_of_ATR_in_response_to_replication_stress RAD17 CLSPN RFC5 ATR-ATRIP-RPA-ssDNA_signaling_complex_(complex) ATR_monomer RFC3 RFC2 Rad17-RFC_complex_(complex) Cdc45_CDK_DDK_Mcm10_Activated_claspin_pre-replicative_complex_(complex) ATM-_and_rad3-related_(ATR)_(complex) RAD1 CDC6 CDC7 RPA_heterotrimer_(complex) Rad17-RFC_complex_bound_to_DNA_(complex) HUS1 Orc2_associated_with_MCM8_(complex) ATRIP ORC6 RAD9 RFC4 DDK_(complex) Rad9-Hus1-Rad1_bound_to_DNA_(complex) ORC4 CDC6_ORC_origin_complex_(complex) CHEK1 MCM10 CDC25C CDC25A ORC5 ORC2 ORC3 ORC1 MCM7 CDK_DDK_Mcm10_pre-replicative_complex_(complex) MCM5 MCM4 MCM3 MCM2 ATR-interacting_protein_(ATRIP)_(complex) Mcm2-7_complex_(complex) MCM8 active_pre-replicative_complex_(complex) MCM6 Rad9-Hus1-Rad1_complex_(complex) Cdc45_CDK_DDK_Mcm10_claspin_pre-replicative_complex_(complex) Cdc45_CDK_DDK_Mcm10_pre-replicative_complex_(complex) RPA1 RPA3 RPA2 CDK2 Mcm10_active_pre-replicative_complex_(complex) DBF4 RPA_complexed_to_ssDNA_(complex) CDC45 ORC_origin_(complex) CDK_(complex)
PID_Activation_of_BH3_only_proteins TFDP1 MAPK8 DP-1_E2F1_complex_(complex) E2F1
REACTOME_15354 Dipeptidase_2_/_LTD4_dipeptidase_2_(complex) gamma-glutamyltransferase_5_(complex) DPEP1 leukotriene_C4_synthase_(complex) LTC4S LTA4H ALOX5 DPEP2
PID_Regulation_of_ornithine_decarboxylase__ODC_ PSMD9 PSMD8 PSMB10 PSMD5 PSMD11 PSMD7 ODC_OAZ_complex_(complex) PSMD1 PSMD3 NQO1 PSMD6 OAZ PSMF1 AZIN1_bound_OAZ_ODC_complex_(complex) AZIN1_bound_OAZ_(complex) ODC1 PSMA2 PSMA3 PSMA1 PSMA6 PSMA7 PSMA4 PSMA5 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 ODC_NQO1_complex_(complex) PSME2 PSME3 PSME1 PSMD2 PSMD4 PSMD14 AZIN1 PSMD10 PSMD13 PSMD12 PSMB9 PSMB8 PSMB7 PSMB6 PSMB5 PSMB4 PSMB3 PSMB2 PSMB1
REACTOME_REACT_15307 Prostacyclin_prostacyclin_receptor_Gs_(inactive)_(complex) Prostacyclin_prostacyclin_receptor_G-protein_Gs_(active)_(complex) G-protein_alpha_(s)_GDP_(complex) Heterotrimeric_G-protein_Gs_(inactive)_(complex) GNG10 GNG11 GNG12 GNG13 GNG2 G-protein_gamma_subunit_(family) IP_receptor_Prostacyclin_(complex) GNGT2 GNB5 GNB4 GNB1 G-protein_beta-gamma_complex_(complex) GNB3 GNB2 G-protein_alpha_(s)_GTP_(complex) PTGIR GNAS Heterotrimeric_G-protein_Gs_(active)_(complex) GNG7 GNG4 GNG5 G-protein_beta_subunit_(family) GNG3 GNGT1 GNG8
REACTOME_REACT_160106 NOTCH1_t(7;9)(NOTCH1_M1580_K2555)_fragment_(complex) NOTCH1 DLL1 DLL4 JAG2 JAG1 NOTCH1_t(7;9)(NOTCH1_M1580_K2555)_(complex)
BIOCYC_PWY-6363 OCRL INPP5A INPP5B INPP1 INPPL1 INPP5F INPP5J INPP5K inositol(myo)-1(or_4)-monophosphatase_2_(complex) IMPA1 IMPA2 IMPAD1 SYNJ1 inositol(myo)-1(or_4)-monophosphatase_1_(complex)
PID_Activation_of_Chaperones_by_ATF6_alpha MBTPS2 HSPA5 MBTPS1 NFYA BiP_unfolded_protein_complex_(complex) ATF6
PID_Histidine_catabolism FTCD_octamer_(complex) HAL UROC1 AMDHD1 FTCD urocanase_(complex)
BIOCYC_PWY-6613 MTHFD2L MTHFD2 MTHFD1 methenyltetrahydrofolate_cyclohydrolase_[multifunctional]_(complex) C1_tetrahydrofolate_synthase_cytoplasmic_C1_THF_synthase bifunctional_methylenetetrahydrofolate_dehydrogenase/cyclohydrolase_mitochondrial_precursor GART
BIOCYC_TRIGLSYN-PWY PPAP2C PPAP2B PPAP2A LCLAT1 GPAT2 MBOAT2 MBOAT1 LPPR4 LPPR3 LPPR2 GPAM DGAT1 DGAT2 PPAPDC1A LPCAT4 LPCAT3 GPAT MOGAT3 MOGAT1 ABHD5 AGPAT6 AGPAT5 AGPAT4 AGPAT3 AGPAT2 AGPAT1 MBOAT7 AGPAT9
PID_Autointegration_results_in_viral_DNA_circles Integrase
BIOCYC_PWY-2161B GGH
BIOCYC_PROPIONMET-PWY PCCB MUT MCEE PCCA propionyl-CoA_carboxylase_(complex)
REACTOME_REACT_19328 Di-peptides/tri-peptides_(complex)
PID_NICD_trafficks_to_nucleus NOTCH4 NOTCH1 NOTCH2 NOTCH3
PANTHER_P00034 Complex_(SOS/Grb2/_Shc)_(complex) B-Raf Complex_(Integrin_beta/Integrin__alpha/_Integrin_beta/Integrin__alpha/_Collagen/Laminin/_Fibronectin)_(complex) ELMO Ras Laminin Abl Complex_(p130CAS/Crk/_Dock180/ELMO)_(complex) Complex_(Integrin_beta/Integrin__alpha/_Caveolin/Integrin__alpha/_Integrin_beta/Collagen/_Laminin/Fibronectin)_(complex) TPI1 Actin CRK Complex_(Csk/Paxillin)_(complex) alpha_actinin VASP Complex_(Crk/C3G/_p130CAS)_(complex) RAP1 Complex_(Paxillin/Crk)_(complex) Csk Rac Arf1 Talin FYN Arf6 FAK Complex_(ILK/PINCH/_Parvin)_(complex) Complex_(PIP2/Vinculin)_(complex) Rho PINCH ERK Complex_(Paxillin/PTP-PEST)_(complex) Complex_(Integrin__alpha/Paxillin/_Integrin_beta/Talin/_Vinculin/Actin/_Integrin__alpha/alpha_actinin/_Actin/Integrin_beta/_Filamin/Collagen/_Laminin/Fibronectin)_(complex) Complex_(Integrin_beta/Integrin__alpha/_Paxillin/FAK/_Talin/Vinculin/_Actin/Integrin__alpha/_alpha_actinin/Actin/_Integrin_beta/Filamin/_Collagen/Laminin/_Fibronectin)_(complex) Src SOS PI3K Parvin p130CAS Paxillin Arp2/3 Shc Complex_(Vinculin/PIP2/_Arp2/3)_(complex) Integrin_beta Integrin_alpha Raf Dock180 Complex_(Vinculin/PIP2/_VASP)_(complex) Filamin CA2 CA1 Collagen Grb2 MEK ASAP1 Vinculin Fibronectin Complex_(Abl/Paxillin)_(complex) ILK GRAF Jnk C3G Complex_(Grb2/SOS/_FAK)_(complex)
REACTOME_REACT_7999 PCNA RPA_heterotrimer_(complex) DNA2 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_RPA_heterotrimer_(complex) RPA1 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_RPA_heterotrimer_dna2_(complex) POLD2 RPA3 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_(complex) Processive_complex_loaded_on_telomere_nicked_DNA_from_adjacent_Okazaki_fragments_(complex) DNA_Polymerase_delta_tetramer_(complex) POLD3 PCNA_homotrimer_(complex) POLD4 Processive_complex_loaded_on_telomere_Okazaki_fragments_Remaining_Flap_(complex) RPA2
PID_Nuclear_Receptor_transcription_pathway NR-MED1_Coactivator_Complex_(complex) MED1
REACTOME_REACT_115852 Resistant_ligand-responsive_EGFR_mutants_(complex) Active_dimers_of_ligand-responsive_EGFR_mutants_sensitive_to_non-covalent_TKIs_(complex) GRB2_GAB1_PIK3R1_(complex) p-EGFR_mutants_p-Y472_771_783_1254-PLCG1_(complex) HRAS RPS27A EGFR GAB1 PLCG1 EGF_EGFR_dimer_(complex) p21_RAS_GDP_(complex) EGF EGF_EGFR_(complex) p21_RAS_GTP_(complex) p21_RAS_(family) CDC37_homodimer_(complex) Ligand-responsive_EGFR_mutants_HSP90_CDC37_(complex) HSP90_homodimer_(complex) NRAS CDC37 Phospho-EGFRvIIImut_HSP90_CDC37_(complex) Ligand-responsive_p-6Y-EGFR_mutants_CBL_(complex) EGF_EGFR_Dimer_Covalent_EGFR_TKIs_(complex) Ligand-responsive_p-6Y-EGFR_mutants_p-Y371-CBL_(complex) Active_dimers_of_ligand-responsive_EGFR_mutants_(complex) GRB2_SOS1_(complex) GRB2_GAB1_PI3Kreg_PI3Kcat-Active_dimers_of_phospho-EGFR_KD_mutants_HSP90_CDC37_(complex) GRB2_SOS1_Phospho-SHC1_Phospho-EGFRmutKD_HSP90_CDC37_(complex) Phospho-EGFRmutKD_PLCgamma1_(complex) GRB2_SOS1_Phospho-EGFRmutKD_HSP90_CDC37_(complex) PIK3R1 GRB2_GAB1_PI3Kreg-Active_dimers_of_phospho-EGFR_KD_mutants_HSP90_CDC37_(complex) Ligand-responsive_p-6Y-EGFR_mutant_dimers_(complex) Activated_EGFRvIIImut_HSP90_CDC37_(complex) EGFRvIII_mutant_HSP90_CDC37_(complex) Active_dimers_of_phospho-EGFR_KD_mutants_HSP90_CDC37_SHC1_(complex) Ligand-responsive_EGFR_mutants_dimer_(complex) Resistant_ligand-responsive_EGFR_mutants_Covalent_EGFR_TKIs_(complex) KRAS Complex_of_heat_shock_protein_90_and_one_of_the_benzoquinoid_ansamycins_(complex) EGF_Ligand-responsive_EGFR_mutants_HSP90_CDC37_(complex) SOS1 EGF_Ligand-responsive_EGFR_mutants_dimer_(complex) Sensitive_ligand-responsive_EGFR_mutants_Non-covalent_EGFR_TKIs_(complex) CBL Ligand-responsive_Ub-p-6Y-EGFR_mutants_p-Y371-CBL_(complex) EGFR_Cetuximab_(complex) UBA52 GRB2 p-EGFR_mutants_p-Y349_350-SHC1_(complex) PIK3CA Activated_phospho-EGFRvIIImut_HSP90_CDC37_(complex) HSP90AA1 ubiquitin_(family) SHC1
BIOCYC_PWY66-341 MSMO1 LBR TM7SF2 NSDHL FDFT1 DHCR7 SC5D EBP LSS CYP51A1 HSD17B7 Emopamil-binding_protein_(complex) SQLE DHCR24
PID_Endogenous_sterols CYP7B1 CYP11A1 CYP1B1 CYP21A2 CYP19A1 CYP27A1 CYP17A1 CYP39A1 CYP51A1 CYP11B2 CYP11B1 CYP7A1 CYP46A1
REACTOME_REACT_118699 RISC__Target_RNA_Complex_with_Inexact_Match_Between_Target_RNA_and_Guide_RNA_(complex) Nonendonucleolytic_RISC__Target_RNA_Complex_with_Exact_Match_between_Target_RNA_and_Guide_RNA_(complex) Nonendonucleolytic_RISC_(complex) TNRC6C TNRC6B TNRC6A RISC_(complex) RNA-induced_Silencing_Complex_(complex) Nonendonucleolytic_Minimal_RISC_(complex) TNRC6_(GW182)_(family)
BIOCYC_PWY-5143 ACSL3 ACSL1 ACSL6 ACSL4 ACSL5 ACSBG1 ACSBG2 SLC27A2
REACTOME_REACT_19342 SrGAP_(family) Glypican-1_HSPG_(complex) RAC1 ROBO1 RAC1-GDP_(complex) CDC42_GDP_(complex) SRGAP1 SRGAP3 SRGAP2 GPC1 SLIT2 ARHGAP39 Robo1_Slit2_KIAA1688_(complex) Robo1_Slit2_SrGAP_(complex) Slit2_Glypican-1_(complex) Robo1_Slit2_Glypican-1_(complex) CDC42
PID_Toll_Like_Receptor_TLR1_TLR2_Cascade TLR1_TLR2_with_ligand_(complex) TLR2 UniProt_Q5FWG5_TLR1 TLR1_TLR2_(complex)
PID_Organic_anion_transporters SLC5A8 SLC17A5 VGLUTs SLC17A1 SLC5A5
BIOCYC_PWY-6281 L-selenocysteinyl-tRNA<SUP>sec</SUP> SELENOPHOSPHATE_SYNTHETASE_SELENIUM_DONOR tRNA<SUP>sec</SUP> <i>O</i>-phospho-L-seryl-tRNA<sup>Sec</sup> SEPHS2 SEPHS1 L-seryl-tRNA<SUP>sec</SUP> SEPSECS PSTK SARS
BIOCYC_PWY-5941-1 AGL G6PC PGM1 PGM2 G6PC2 PYGB glycogen_phosphorylase__muscle_isoform_(complex) G6PC3 glycogen_phosphorylase__liver_isoform_(complex) glycogen_phosphorylase__brain_isoform_(complex) PYGL PYGM
REACTOME_REACT_160086 WASP/N-WASP_(family) ACTG1 IGHG4 clustered_IgG-Ag_p-FCGRs_(complex) IGHG1 IGHG2 IGHG3 BRK1 HV305_HUMAN WAVEs_(family) p-Y291-WASP/p-Y256-N-WASP_(family) Ig_gamma_C_region_(family) ELMO_(family) p-WRC_(complex) HV321_HUMAN HV205_HUMAN Ig_gamma_heavy_chain_(complex) MYO5A HV206_HUMAN Activated_WAVE2_and_WASP/N-WASP_ARP2/3_complex_G-actin_(complex) NCKIPSD Ig_Heavy_Chain_V_Region_(family) MYO1C HSP-90_(family) p-ABI_(family) HV107_HUMAN HV314_HUMAN SYK ARPC1A HV313_HUMAN actin_ATP_(complex) GRB2 HV310_HUMAN ARP2/3_complex_(ATP_bound)_(complex) ACTB HV308_HUMAN ELMO1 ELMO2 Activated_WAVE2_and_WASP/N-WASP_(complex) p-WAVE_(family) HV304_HUMAN DOCK1 p-Vav_(family) HV209_HUMAN Ig_G_Antibody_(complex) CRK Actin_filament_bound_Myosin-X_(complex) WAVE_Regulatory_Complex_(complex) Ig_Antibody_Light_Chain_(complex) HV319_HUMAN pCofilin__Active_LIMK-1_(complex) HV203_HUMAN HV316_HUMAN CRKII_DOCK180_ELMO_complex_recruited_to_phagocytic_cup_(complex) WIP_family_proteins_(family) CRK_DOCK180_ELMO_(complex) HV105_HUMAN Actin_ADP_(complex) clustered_IgG-Ag_p-FCGRs_p-6Y-SYK_p-VAV_(complex) ARPC3 ARPC2 HV302_HUMAN ARPC5 ARPC4 HV102_HUMAN HV306_HUMAN Mother_filament_branching_complex_(complex) UniProt_A2KUC3_IGHV HV208_HUMAN VAV1 VAV3 VAV2 PAK1 HV315_HUMAN HV207_HUMAN HV312_HUMAN MYO10 ACTR3 ACTR2 HV201_HUMAN HV106_HUMAN actin_(family) MYH2 HSP90AB1 HV202_HUMAN MYH9 Myosin-Actin_filaments_(complex) Mother_filament_ARP2/3_actin_GDP_(complex) HV311_HUMAN clustered_IgG-Ag_p-FCGRs_p-6Y-SYK_(complex) RAC1/CDC42_p-S144_T423-PAK_(complex) HV317_HUMAN CDC42-GTP_WASP/N-WASP_WIP_SH3_proteins_(complex) HV303_HUMAN WAS RAC1/CDC42_PAK_dimer_(complex) Myosin_(family) HV101_HUMAN clustered_IgG-Ag_p-FCGRs_p-6Y-SYK_VAV_(complex) HV307_HUMAN CDC42-GTP_(complex) MYO9B HSP90AA1 Active_RAC1/CDC42_(complex) Active_LIMK1_(complex) Myosin-X_dimer_(complex) p-WRC_IRSp53/58_RAC1-GTP_PIP3_(complex) CDC42 CYFIP2 SH3_domain_proteins_(family) CDC42-GTP_p-WASP/p-N-WASP_WIP_SH3_proteins_(complex) LIMK1 WASL PAK1_(dimer)_(complex) RAC1-GTP_(complex) WRC_IRSp53/58_RAC1-GTP_PIP3_(complex) HV104_HUMAN HV309_HUMAN WASF2 WASF3 VAV_(family) HV320_HUMAN Mother_filament_branching_complex_daughter_filament_(complex) NCKAP1 RAC1-GDP_(complex) HV204_HUMAN HV318_HUMAN RAC1 Antigen-antibody_complex_(complex) HV301_HUMAN WIPF3 pLIMK_dimer_HSP-90_(complex) CFL1 BAIAP2 ARP2_ATP_(complex) CDC42-GTP_WASP/N-WASP_(complex) WASF1 NCK1 ABI2 ABI1 ARP3_ATP_(complex) ABI_(family) WIPF2 WIPF1 UniProt_Q6PIL0_IGHV7-81
PID_Class_A_1__Rhodopsin_like_receptors_ pH_sensing_receptors Niacin_receptors_niacin_(complex) pH_sensing_receptors_H+_(complex) PAF_receptor_PAF_(complex) Melatonin_receptors_melatonin_(complex) Niacin_receptors GPBAR1 Cannabinoid_receptor_2-AG_(complex) GPR18 GPR39 PTAFR GPR39_Zn++_(complex) G-protein_coupled_bile_acid_receptor__Bile_acids_(complex) N-arachidonyl_glycine_receptor_NAGly_(complex) Melatonin_receptors Cannabinoid_receptors
PID_ifngpathway Erk1-2-active CRKL IFN-gamma/IFN-gammaR/JAK1/JAK1/JAK2/JAK2/SOCS1_(complex) PI3K_(complex) SMAD7 AKT1 MAP2K1 IFNGR1 CAMKII_(family) IL1B RAP1/GTP_(complex) STAT1_(dimer)/PIAS1_(complex) CEBPB CALM2 STAT1 STAT1_(dimer)_(complex) STAT1_(dimer)/PIASy_(complex) PIK3CA MAP3K1 IFN-gamma/IFN-gammaR/JAK1/JAK1/JAK2/JAK2_(complex) Caspase_1_(tetramer)_(complex) JAK2 PIK3R1 JAK1 CBL/CRKL/C3G_(complex) STAT1_(dimer)/SHP2_(complex) DAPK1 STAT3 IFNG CEBPB/PTGES2/Cbp/p300_(complex) PRKCD MTOR PTPN2 RAPGEF1 STAT3_(dimer)-active_(complex) Cbp/p300 IFN-gamma/IFN-gammaR/JAK1/JAK1/JAK2/JAK2_/TCPTP_(complex) SOCS1 IL1_beta_fragment CASP1 PTGES2 PTPN11 STAT1_(dimer)/Cbp/p300_(complex) CBL CaM/Ca2+_(complex) MAP3K11 ERK1-2 PIAS1 PIAS4 RAP1 CaM/Ca2+/CAMKII_(complex)
PID_eif4pathway Met-tRNA GHR PI3K_(complex) 40s_Ribosome_subunit MKNK1 MAPK14 AKT1 PKC EIF-4F_(complex) PIK3CA RPS6KB1 MAPK3 MAPK1 PIK3R1 PABPC1 48S/S6_(complex) GH/GH_R_(complex) PSMC4 GH_R/IRS-1_(complex) MTOR EIF4E EIF-4E/EIF4EBP_(complex) PABP/EIF-4F_(complex) GH1 PPP2CA EIF4G1 IRS1 PTEN PDK2 EIF4EBP1 PDPK1 EIF4A1
REACTOME_REACT_163906 MUSK TGFB1 BGN_Collagen_types_I__VI__(IX)_(complex) TGFB3 LUM ACAN Aggrecan_HA_HAPLN1_(complex) BGN AGRN Tenascins_C__R__(X__N)_Lecticans_(complex) COMP_pentamer_(complex) NCAM1 Integrin_alphaVbeta1_(complex) LRP4_MUSK_(complex) IBSP Integrins_alphaVbeta1__alphaVbeta3__alphaVbeta5__alpha2bbeta3_(complex) DCN DSPP(463-1301)_Integrin_alphaVbeta1_(complex) Laminins_with_gamma-1_(complex) AGRN_LRP4_MUSK_(complex) Vitronectin_Plasminogen_activator_inhibitor_1_(complex) Biglycan_(family) Tenascins_C__R__(X__N)_(complex) ASPN SPARC Agrin_Laminins_with_gamma-1_(complex) SERPINE1 AGRN_Alpha-dystroglycan_(complex) AGRN_Beta_amyloid_fibril_(complex) FMOD BGN_Collagen_types_II__III_(complex) SLRPs_TGF_beta_(complex) DMP1_Integrin_alphVbeta3_(complex) Integrin_alphaVbeta3__alphaVbeta6__alpha2beta1__alpha7beta1__alpha8beta1__alpha9beta1__alphaXbeta1_(complex) ITGB1 TNC_Integrin_alphaVbeta3__alphaVbeta6__alpha2beta1__alpha7beta1__alpha8beta1__alpha9beta1__alphaXbeta1_(complex) ITGB3 Integrin_alphaVbeta3_(complex) COMP AGRN_NCAM1__PTPRS_(complex) DMP1 VTN_Collagen_type_I_IV_VI_(complex) IBSP_Collagen_type_I_fibril_(complex) Collagen_type_I_fibril_SPARC_Hydroxylapatitie_Ca2+_(complex) NCAM1__PTPRS_(family) Tenascins_C__R__(X__N)_Fibronectin_matrix_(complex) DAG1 TNC PTPRS COMP_pentamer_COMP_interactors_(complex) Aggrecan_(family) TGFB2 SLRPs_(family) VTN VTN_Collagen_types_II_III_V_(complex) DCN_Collagen_type_I__II__III__VI_fibrils_(complex) LRP4 VTN_Integrins_alphaVbeta1__alphaVbeta3__alphaVbeta5__alpha2bbeta3_(complex) ITGAV Tenascin-C_hexamer_(complex) TGF-beta_(family) DSPP HAPLN1
PID_Polymerase_switching POLA2 POLA1 RFC5 RFC4 RFC1 RFC3 RFC2 DNA_Polymerase_delta_tetramer_(complex) RNA_primer-DNA_primer_origin_duplex_PCNA_(complex) DNA_Pol_alpha_primase_(complex) POLD1 POLD2 POLD3 POLD4 PRIM2 PRIM1 PCNA RFC_Heteropentamer_RNA_primer-DNA_primer_origin_duplex_(complex) RFC_Heteropentamer_(complex) RFC_Heteropentamer_RNA_primer-DNA_primer_origin_duplex_PCNA_homotrimer_(complex) RNA_primer-DNA_primer_origin_duplex_(complex) PCNA_homotrimer_(complex) RNA_primer_origin_duplex_DNA_polymerase_alpha_primase_complex_(complex) Processive_complex_(complex)
REACTOME_REACT_115574 Defensins_alpha_1-4_(family) gp120_homotrimer_(complex) Alpha-defensins_(family) UniProt_P04578_env Pro-defensins_alpha_1-4_(family) Defensins_alpha_1-3_(family) Alpha-defensin_dimers_(complex) DEFA5 Defensins_alpha_1-3_CD4_(complex) CD4 DEFA6 Alpha-defensin_dimers_anionic_phospholipids_(complex) DEFA4 DEFA3 HNP1-3_gp120_(complex) DEFA1B Alpha-defensin_pore_complex_(complex)
BIOCYC_PWY4FS-6 PCYT2 CEPT1 EPT1 ETNK2 ETNK1 CHKB
PID_p75_NTR_receptor_mediated_signalling NGF mature_NGF_homodimer_p75NTR_(complex) NGFR mature_beta-NGF_homodimer_(complex)
PANTHER_P00040 AC Complex_(GTP/G-protein)_(complex) Ca(2+) Complex_(SNARE_Complex/Ca2+)_(complex) SNARE_Complex Complex_(mGluR2/3/_Glutamate/G-protein/_GDP)_(complex) PKA mGluR2/3 G-protein
BIOCYC_TRYPTOPHAN-DEGRADATION-1 KMO KYNU mitochondrial_acetyl-CoA_acetyltransferase_(complex) HADHB AFMID cytosolic_acetyl-CoA_acetyltransferase_(complex) ACAT1 ACAT2 TDO2 ETFH<sub>2</sub>_(complex) an_oxidized_electron-transferring_flavoprotein_(complex) ACMSD GCDH HAAO
PID_LDL_mediated_lipid_transport apolipoprotein(a)_LDL_complex_(complex) CETP LDLR low-density_lipoprotein_complex_(complex) APOB LDL_LDLR_complex_(complex) CETP_triacylglycerol_complex_(complex) LDLRAP1 LPA
PID_Downstream_TCR_signaling TRAF6_trimer_bound_to_CBM_complex_(complex) TAK1/TAB2_complex_bound_to_TRAF6/CBM_complex_(complex) MALT1_trimer_bound_to_Bcl10_and_CARMA1_trimer_(complex) Ub-NEMO_(complex) PI3K_(complex) CD3_epsilon_delta_(complex) CD4 CD247 IKBKG PDK1_bound_to_either_PIP3_or_PI(3_4)P2_(complex) Activated_CARMA1_(complex) Active_PKC_theta_bound_to_DAG_(complex) Ub-TRAF6_trimer_bound_to_CBM_complex_(complex) PI3K-regulatory_subunit TRAT1 MAP3K7 MALT1_trimer_(complex) Inactive_PKC_theta_bound_to_DAG_(complex) TCR_chain_alpha TAB2/TAK1_complex_(complex) PI3K_bound_to_TRAT_(complex) phosphorylated_TAK1_bound_to_TAB2_(complex) CARMA1_trimer_(complex) MALT1 NFKBIA TRAF6 CARD11 MHC_Class_II_bearing_antigen_peptide_(complex) CHUK PI3K-catalytic_subunit Poly-ubiquitinated_TRAF6_(complex) T-cell_receptor_(complex) PRKCQ Bcl10_trimer_bound_to_CARMA1_trimer_(complex) BCL10 CARMA1_bound_to_PDK1_(complex) IKBKB CD3_epsilon_gamma_(complex) INPP5D PKC_theta_(opened_conformation)_bound_to_DAG_(complex) Antigen-bearing_MHC_Class_II__TCR_complex_CD4__Lck_phosphorylated_at_Tyr394_(complex) T-cell_receptor_complex_(complex) Phosphorylated_Bcl10_bound_to_CARMA1_and_RIP2_(complex) TCR_chain_beta LCK PTEN RIPK2 IKK_complex_with_phosphorylated_IKK_beta_(complex) PTEN_(Mg2+_cofactor)_(complex) TAB2 Bcl10_bound_to_CARMA1_(complex) PDPK1 IKK_complex_with_Ub-NEMO_(complex) CD3D CD3E CD3G
REACTOME_REACT_12519 PECAM-1_PLC_gamma1_complex_(complex) PECAM1 ITGB3 INPP5D PECAM-1_SHP-1_complex_(complex) PTPN11 ITGAV PECAM-1_PECAM-1_(complex) Integrin_alphaVbeta3_PECAM1_(complex) PLCG1 PECAM-1_SHP-2_complex_(complex) Integrin_alphaVbeta3_(complex) p-PECAM1_p-PECAM1_(complex) PECAM-1_SHIP1_complex_(complex) PTPN6
PID_phospho_PLA2_pathway Active_PLA2_phosphatidylcholine_(complex) PLA2G4A
BIOCYC_PWY-4984 arginase-2__mitochondrial_(complex) OTCase_(complex) argininosuccinate_synthase_(complex) ARG2 OTC ASL_(complex) liver-type_arginase_(complex) argininosuccinate_lyase CITRULLINE_ASPARTATE_LIGASE ASS1 CPS1
PID_FGFR1_ligand_binding_and_activation GRB2 SDC2 Activated_FGFR_complexed_with_phosphorylated_FRS2__GRB2_and_CBL_(complex) CBL Phospho-FRS2
PID_Unblocking_of_NMDA_receptor__glutamate_binding_and_activation ACTN2 DLG4 CaMKII_alpha/beta_subunits NEFL NR2_subunits CaMKII_delta/gamma_subunits NR2_interacting_proteins_(complex) tcag7.318 CaMKII_(complex) NMDA_receptor_complex_(complex) NMDA_receptor_ligand_complex_(complex) NR1_interacting_proteins_(complex)
PID_Formation_of_incision_complex_in_GG_NER RAD23B ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 pre-incision_complex_in_GG-NER_(complex) XPC_HR23B_damaged_DNA_complex_(complex) TFIIH_(complex) RPA_heterotrimer_(complex) ERCC1_XPF_complex_(complex) XPC DDB2 DDB1 XPA GTF2H3 GTF2H2 GTF2H1 GTF2H4 XPC_HR23B_complex_(complex) MNAT1 pre-incision_complex_with_open_DNA_bubble_(complex) RPA1 RPA3 RPA2 incision_complex_for_GG-NER_(complex) CDK7 CAK_(complex) CCNH
PID_FGFR1c_and_Klotho_ligand_binding_and_activation Klotho_homodimer_(complex) SDC2 Activated_FGFR_complexed_with_phosphorylated_FRS2__GRB2_and_CBL_(complex) CBL Phospho-FRS2 GRB2 FGFR1c_homodimer_(complex) FGF23_bound_to_Klotho_and_FGFR1c_(complex) Activated_FGFR1c_bound_to_FGF23_Klotho_(complex) Klotho_bound_to_FGF23_(complex) FGF23 FGFR1
REACTOME_REACT_25299 DSCAM_DCC_(complex) DSCAM_pPAK(S144)_Rac1-GTP_(complex) MAPK14 MAPK11 MAPK12 MAPK13 RAC1-GTP_(complex) DCC DSCAM pPAK(S144)_Rac1-GTP_(complex) MAPK8 DSCAM/DSCAML1_(family) RAC1 Phospho-MAP_kinase_p38_(Mg2+_cofactor)_(complex) MAP_kinase_p38_(Mg2+_cofactor)_(complex) DSCAM/DSCAML1_homodimers_(complex) NTN1 DSCAM_netrin_(complex) p38_MAP_Kinase_(family) Phospho-p38_MAPK_alpha/beta_(family) PAK1 DSCAML1
PID_Effects_of_PIP2_hydrolysis Diacylglycerol_kinase IP3_receptor_bound_to_IP3_and_Ca++_(complex) IP3_receptor_(complex)
PID_Nectin_Necl__trans_heterodimerization Necl-1_Nectin-3_trans_heterodimer_(complex) Necl-1_Nectin-1_trans_heterodimer_(complex) Necl-5_Nectin-3_trans_heterodimer_(complex) Nectin-4_cis_homodimer_(complex) Nectin-3_Necl-2_trans_heterodimer_(complex) Nectin-1_Nectin-3_trans_heterodimer_(complex) Nectin-2_cis_homodimer_(complex) PVRL1 PVRL4 PVRL3 Nectin-2_Nectin-3_transheterodimer_(complex) PVRL2 Nectin-3_cis_homodimer_(complex) Necl-1_Necl-2_trans_heterodimer_(complex) PVR Nectin-1_Nectin-4_trans_heterodimer_(complex) Nectin-1_cis_homodimer_(complex) CADM3 CADM1
PID_A_third_proteolytic_cleavage_releases_NICD gamma-secretase_complex_(complex) NOTCH4 NOTCH1 NOTCH2 NOTCH3 Presenilin_homodimer_(complex) Nicastrin PSENEN Presenilin
BIOCYC_PWY66-389 ALDH3A2 PECR
PID_notch_pathway NOTCH1_heterodimer/CNTN1_(complex) YY1 DTX1 ITCH NEURL NECD/MAGP1-2_(complex) Gamma_Secretase_(complex) NCSTN ADAM10 NOTCH1_heterodimer/Delta_1_(complex) ADAM12 CNTN1 CNTN6 DSL_ligands NOTCH1_heterodimer/DLK1_(complex) PSENEN RBPJ/NICD/MAML1-2_(complex) NOTCH3 RAB11/GTP_(complex) NOTCH3_heterodimer_(complex) MAGP1-2 FURIN APH1B APH1A NOTCH1_heterodimer_(complex) SKP1 NECD/Jagged_1_(complex) RBPJ LNX1 MIB1 NECD/Delta_1_(complex) RAB11A NOTCH4/Delta_4_(complex) NOTCH1_heterodimer/DNER_(complex) RBPJ/NICD/MAML1-2/p300_(complex) NOTCH1_heterodimer/NB-3_(complex) NOTCH2_heterodimer/DSL_(complex) MARK2 JAG2 JAG1 CUL1 FBXW7 NOTCH3_heterodimer/DSL_(complex) RBPJ/NICD_(complex) EPS15 NOTCH2 NOTCH2_heterodimer/CNTN1_(complex) DLL1 DLL3 DLL4 NOTCH2_heterodimer_(complex) NOTCH1_heterodimer/sDelta_1_(complex) SCF/SEL10_(complex) MAML1-2 EP300 PSEN1_(dimer)_(complex) NOTCH1/Jagged_1_(complex) NOTCH1 DNER NUMB NUMB/ITCH_(complex) NECD2/DSL_(complex) NOTCH1_heterodimer/Jagged_1_(complex) DLK1 NOTCH4 BTRC DNM1/GTP_(complex) MFAP5 CBL NOTCH1_heterodimer/Jagged_2_(complex) NECD/sDelta_1_(complex) NECD/Jagged_2_(complex) DNM1 NICD/YY1_(complex) NOTCH1_heterodimer/MAGP1-2_(complex)
REACTOME_REACT_13472 LMNA LMNB1
PID_nthipathway MAP4K4 IKKs SMAD4 TGFBR1 SMAD3 MAPK14 Dexamethasone/glucocorticoid_receptor/Dexamethasone/glucocorticoid_receptor_(complex) MAPK11 TGF-beta/TGF-beta-R1/TGF-beta-R2_(complex) IL1B TLR2 MAP3K7 RELA MYD88 DUSP1 p300/CBP/RELA/p50_(complex) TGFBR2 NR3C1 RELA/p50_(complex) Dexamethasone/glucocorticoid_receptor_(complex) TNF TGF-beta EP300 p50 MAP2K3 NTHI/TLR2/MYD88_(complex) SMAD3/SMAD4_(complex) CREBBP IL8 MAP2K6
PID_proteasomepathway Rpt6 RPN1 RPN2 Rpt5 Rpt2 Rpt3 Rpt1 PSMD4 Rpt4 PSMD3 Substrate/ubiquitin_(complex) ubiquitin UBE3A PSMA2 PSMA3 PSMA1 PSMA6 PSMA7 PSMA4 PSMA5 Rpn12 PA-28_Activator PA28_Proteasome_(complex) Substrate Rpn7 E2/ubiquitin_(complex) Rpn9 Hybrid_Proteasome_(complex) Rpn8 UBE2A PSMD14 PSMD11 PSMD12 PA700_Activator_(complex) PSMB7 PSMB6 PSMB5 PSMB4 PSMB3 PSMB2 PSMB1
PID_Activation__myristolyation_of_BID_and_translocation_to_mitochondria GZMB BID NMT1 Caspase-8_dimer_(complex) CASP8
PID_Cleavage_of_Growing_Transcript_in_the_Termination_Region_ Cap_Binding_Complex_(CBC)_(complex) SNRPD3 NCBP1 NCBP2 CF_II_(complex) CLP1 U7_snRNP_ZFP100_Complex_(complex) LSM10 LSM11 PCF11 SNRPB U7_snRNP-specific_Sm_core_complex_(complex) ZNF473 CF_I_(complex) mRNA_3prime-end_cleavage_factor_(complex) CPSF7 NUDT21 SNRPF SNRPG Mature_intronless_transcript_derived_Histone_pre-mRNA_CBC_complex_(complex) SNRPE
REACTOME_REACT_11096 COPZ1 COPA Coatomer_Arf1-GTP_GAP_Complex_(complex) COPE ARF1 COPG1 ARCN1 Coatomer_(complex) ARFGAP1 COPB1 ARF1/GTP_(complex) COPB2 ARF1/GDP_(complex) Coatomer_Arf1-GTP_Complex_(complex)
PANTHER_P00042 IP3R Complex_(VAChT/ACh)_(complex) Complex_(CHT1/choline)_(complex) CHT1 PKC VAChT PLC NMDA
PID_Transport_of_Mature_mRNAs_Derived_from_Intronless_Transcripts NUP88 AAAS NCBP1 NCBP2 NUP85 NUP62 NUP133 NUP98 NUP43 NUP188 Cap_Binding_Complex_(CBC)_(complex) NUP214 NUP210 RANBP2 POM121 NXF1 NUP107 Nup107_Complex_(complex) NUP160 NUP93 ALYREF TPR Nup62_Complex_(complex) NUPL1 NUPL2 EIF4E SEH1L NUP50 NUP54 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 NUP153 NUP155 NUP205 RAE1
PID_G2_M_Transition CDC25C Cdc25 WEE1
REACTOME_REACT_6344 HIV-1_Tat-containing_arrested_processive_elongation_complex_(complex) NELFB TCEB2 TCEB1 NELFA NELFE TCEB3 NELF_complex_(complex) CCNT1 Elongin_B_C_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) P-TEFb(Cyclin_T1_Cdk9)_complex_(complex) SUPT5H SSRP1 CDK9 FACT_complex_(complex) POLR2D Tat_P-TEFb(Cyclin_T1_Cdk9)_complex_(complex) ELL SUPT16H Elongin_Complex_(complex) TCEA1 POLR2E HIV-1_Tat-containing_aborted_elongation_complex_after_arrest_(complex) POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L CTDP1 POLR2I POLR2H POLR2K POLR2J GTF2F1 NELFCD GTF2F2 HIV-1_Tat-containing_processive_elongation_complex_(complex) SUPT4H1 UniProt_P04608_tat DSIF_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex)
PID_Activated_AMPK_stimulates_fatty_acid_oxidation_in_muscle AMPK_gamma ACSL1 AMPK_heterotrimer_(active)_(complex) AMPK_alpha ACACB Phosphorylated_AMPK_alpha AMPK_heterotrimer_(complex) PRKAA2 AMPK_beta LKB1_STRAD_MO25_(complex) STRAD STK11 PRKAG2 Phosphorylated_AMPK_heterotrimer_(complex) PRKAB2 MO25
PID_Tryptophan_catabolism IDO1 2-amino-3-carboxymuconate-6-semialdehyde_decarboxylase_homodimer_(complex) KMO kynureninase_dimer_(complex) tryptophan_2_3-dioxygenase_tetramer_(complex) AFMID indoleamine_2_3-dioxygenase_heme_(complex) KYNU HAAO 3-hydroxyanthranilate_oxygenase_holoenzyme_(complex) ACMSD TDO2
PID_Inactivation_of_APC_C_via_direct_inhibition_of_the_APC_C_complex UBE2D1 phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) MAD2L1 CDC16 BUB3 BUB1B CDC27 CDC23 UBE2C ANAPC11 ANAPC10 UBE2E1 CDC20 hBUBR1_hBUB3_MAD2__CDC20_complex_(complex) CDC26 ANAPC1 MCC_APC/C_complex_(complex) ANAPC2 ANAPC5 ANAPC4 ANAPC7
PID_BH3_only_proteins_associate_with_and_inactivate_anti_apoptotic_BCL_2_members BCL2L1 Bcl-XL_BH3-only_protein_complex_(complex) Bcl2_BH3-only_protein_complex_(complex) BID tBID_BCL-2_(complex) BCL2
PID__2_LTR_circle_formation Ku_proteins_bound_to_viral_DNA_(complex) linear_duplex_viral_DNA_(complex) XRCC4_DNA_ligase_IV_complex_(complex) viral_DNA_Ku_proteins_XRCC4_DNA_ligase_IV_complex_(complex) XRCC4 LIG4 XRCC5 Integrase Ku70_Ku80_heterodimer_(complex) XRCC6
PID_G_beta_gamma_signalling_through_PI3Kgamma PI3K_gamma_(complex) PIP3_RhoA_(complex) PDK1_AKT_(complex) G-protein_beta-gamma_PI3K_gamma_(complex) GNB1 G-protein_beta-gamma_complex_(complex) PI3-kinase_gamma__regulatory_subunit AKT1 GNG2 PDK1_AKT_PIP3_(complex) PDPK1 RHOA PIK3CG
PID_Signalling_to_STAT3 NGF STAT3 Activated_TrkA_receptor_complex_(complex) beta-NGF_homodimer_(complex) NTRK1 Phospho-STAT3
REACTOME_REACT_1181 Orc3_Orc2_origin_(complex) UBC Orc2_origin_(complex) geminin_ubiquitin_complex_(complex) ORC4 ORC5 ORC2 ORC3 ORC1 Orc5_Orc3_Orc2_origin_(complex) Orc4_Orc5_Orc3_Orc2_origin_(complex) UBA52 RPS27A UBB Orc1_Orc4_Orc5_Orc3_Orc2_origin_(complex) GMNN ubiquitin_(family)
REACTOME_REACT_16907 CCT/TriC_substrate_complex_(complex) CCT/TriC(ADP)_Sphingosine_kinase_1_(complex) SPHK1 CCT8 CCT2 CCT3 CCT/TriC(ADP)_(complex) CCT7 CCT4 CCT5 TCP1 CCT6A
BIOCYC_PWY-6121 GART PPAT GLUTAMINE_PHOSPHORIBOSYLPYROPHOSPHATE_AMIDOTRANSFERASE_ATASE_GPAT PFAS
REACTOME_REACT_11240 STX1A STX8 STX1B hCG_96107 STX3 STX2 STX5 STX4 STX7 STX6 STX11 STX10 STX12 STX16 Syntaxins_(family) Syntaxin_fragment_(family)
REACTOME_REACT_121208 Cam-PDE_1_homodimer_(complex) active_Cam-PDE_1_(complex)
PID_Platelet_degranulation_ Platelet_releasate_secretory_granule_proteins HSPA5 PSAP Platelet_alpha_granule_membrane_components CALU Platelet_releasate_cytosolic_proteins Platelet_dense_granule_membrane_components Platelet_releasate_(inferred)_cytosolic_proteins
PID_Translocation_of_BoNT_Light_chain Gangliosides_Synaptogamin_(complex) Synaptotagmins BoNT_Heavy_Chain BoNT_with_conformational_change_in_Heavy_chain_N-terminal_(complex)
REACTOME_REACT_19230 CAP_Abl_Robo1_Slit2_Glypican-1_(complex) Abl_Robo1_Slit2_Glypican-1_(complex) CLASP_(family) CLASP1 Glypican-1_HSPG_(complex) ROBO1 SLIT2 Slit2_Glypican-1_(complex) CAP1 CAP2 Robo1_Slit2_Glypican-1_(complex) GPC1 Clasp_Abl_Robo1_Slit2_Glypican-1_(complex) Abl_tyrosine_kinases_(family) ABL1 Abl_pRobo1_slit2_Glypican-1_(complex) ABL2 Adenylyl_cyclase-associated_proteins_(family) CLASP2
PID_Digestion_of_dietary_lipid PNLIPRP2 pancreatic_lipase_colipase_complex_(complex) CLPS CEL dimerized_CEL_bile_salt_complex_(complex) CEL_bile_salt_complex_(complex) PNLIP
PID_barrmapkpathway Ligand/GPCR(+)/Arrestin/RAF1/MEK1/MEK2/ERK1/ERK2(cy)_(complex) Ligand MAPK3 Ligand/GPCR(+)/g-beta/g-gamma_(complex) GNB1 MAP2K1 G-protein_Receptor MAP2K2 GPCR MAPK1 DNM1 GNGT1 ARRB1 Ligand/GPCR(+)/Arrestin_(complex) Ligand/GPCR(+)/Arrestin/RAF1/MEK1/MEK2/ERK1/ERK2_(complex) RAF1 ADRBK1
BIOCYC_PWY0-1182 HKDC1 GALM GCK TREH ALPHA_ALPHA_TREHALASE_ALPHA_ALPHA_TREHALOSE_GLUCOHYDROLASE
BIOCYC_PWY-5664 GCH1 SIMILAR_TO_SEPIAPTERIN_REDUCTASE SPR_(complex) GTP_cyclohydrolase_I_(complex) PTS PTPS_(complex)
BIOCYC_PWY-6362 ITPK1 INPP5A INPP5B INPP5D INPPL1 INPP5J IPMK ITPKA ITPKC ITPKB SYNJ1 SYNJ2 OCRL IPPK
PID_MyD88_cascade IRAK4_MyD88_Mal_activated_TLR_receptor_(complex) IRAK1-P_IRAK4_MyD88_activated_TLR_(complex) MYD88 TRAF6 TIRAP IRAK1_IRAK4_MyD88_activated_TLR_(complex) MAP3K1 IRAK1-P(n)_TRAF6_(complex) MyD88_Mal_complexed_with_the_activated_TLR_receptor_(complex) MEKK1_TRAF6_IRAK1-P(n)_(complex) ECSIT SIGIRR IRAK3 IRAK1 IRAK1-P(n)_IRAK4_MyD88_activated_TLR_(complex) IRAK4 IRAK1-PP_IRAK4_MyD88_activated_TLR_(complex)
REACTOME_REACT_120996 HMMR HA_receptors_(family) LYVE1 STAB2 CD44 HA_HAR_HYAL2_SLC9A1_(complex) HA_HAR_HYAL2_(complex) HYAL2 SLC9A1
REACTOME_REACT_8027 PCNA RPA_heterotrimer_(complex) DNA2 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_RPA_heterotrimer_(complex) RPA1 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_RPA_heterotrimer_dna2_(complex) POLD2 RPA3 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_(complex) Processive_complex_loaded_on_telomere_nicked_DNA_from_adjacent_Okazaki_fragments_(complex) POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 PCNA_homotrimer_(complex) POLD4 Processive_complex_loaded_on_telomere_Okazaki_fragments_Remaining_Flap_(complex) RPA2
REACTOME_REACT_1650 DYNLL1 BIM_sequestered_to_dynein_(DLC1)_(complex) BCL2L11 Dynein_(DLC1)_on_microtubules_(complex)
BIOCYC_PROSYN-PWY PYCR2 ALDH18A1 PYCR1_(complex) PYCRL
REACTOME_REACT_1096 upstream_mRNA_fragment_CPSF_PAP_PABPN1_complex_(complex) Cap_Binding_Complex_(CBC)_(complex) NCBP1 NCBP2 CF_II_(complex) capped_intronless_pre-mRNA_CBC_complex_(complex) Mature_intronless_derived_mRNA_complex_(complex) CPSF7 NUDT21 CPSF3 CPSF2 CPSF1 Cleavage_and_polyadenylation_specificity_factor_(complex) PAPOLA PCF11 CstF_CPSF_capped_intronless_pre-mRNA_CBC_complex_(complex) PABPN1 CF_I_(complex) Cleavage_Stimulation_Factor_(complex) CLP1 CSTF1 CSTF3 CSTF2 CPSF_capped_intronless_pre-mRNA_CBC_complex_(complex) intronless_pre-mRNA_cleavage_complex_(complex)
PID_pdgfpathway PDGFRA PI3K_(complex) HRAS PLCG1 MAP2K4 RAF1 PDGF/PDGF/PDGF_R/PDGF_R_(complex) STAT3 STAT1 PKC PIK3CA SHC/GRB2/SOS-1_(complex) MAP3K1 JUN MAPK3 ELK1 PIK3R1 JAK1 MAPK8 AP-1_(complex) PDGFA SRF SHC1 FOS STAT1/STAT3_(complex) RASA1 CSNK2A1 ELK-1/SRF/SRF_(complex) SOS1 MAP2K1 GRB2
BIOCYC_PWY-4821 UGDH UXS1
PID_Glycogen_breakdown__glycogenolysis_ phosphorylase_kinase_complex_(PHKL)_(complex) AGL glycogen_phosphorylase__muscle_form__dimer_b_(complex) glycogenin-1_dimer_(complex) glycogen_phosphorylase__brain_form__tetramer_a_(complex) glycogen_phosphorylase__liver_form__dimer_b_(complex) PGYM_b_dimer_AMP_(complex) GYG1 glycogen_phosphorylase__muscle_form__dimer_a_(complex) CALM2 poly((1_4)-alpha-glucosyl)_glycogenin-2_dimer_(complex) limit_dextrin-glycogenin-2_dimer_(complex) PHKB PYGB glycogenin-2_dimer_(complex) GYG2 PYGL glycogen-glycogenin-1_dimer_(complex) PHKG1 glycogen-glycogenin-2_dimer_(complex) phosphorylase_kinase_complex_(PHKM)_(complex) PHKA1 PHKA2 limit_dextrin-glycogenin-1_dimer_(complex) glycogen_phosphorylase__liver_form__dimer_a_(complex) PHKG2 PGYB_b_dimer_AMP_(complex) glycogen_phosphorylase__brain_form__dimer_b_(complex)
REACTOME_REACT_163773 DHX9 IRF7 DHX36_CpG_(complex) Nuclear_factor_NF-kappa-B_(family) DHX9/DHX36_CpG_(complex) NF-kB_complex_(complex) p-2S-IRF7_p-2S-IRF7_(complex) DHX9_CpG_(complex) DHX9/DHX36_CpG_MyD88_(complex) NFKB1 NFKB2 MYD88 RELA DHX36
BIOCYC_PWY-5386 HAGH GLO1 LDHD
REACTOME_REACT_318 Platelet_dense_granule_membrane_components_(family) POTEKP HSPA5 Platelet_releasate_(inferred)_cytosolic_proteins_(family) SCG3 HABP4 Platelet_releasate_cytosolic_proteins_(family) APOA1 Platelet_releasate_secretory_granule_proteins_(family) CALM2 CAP1 TLN1 BRPF3 TTN TF CD63 WDR1 SOD1 VCL LAMP2 CFL1 TUBA4A PLEK PSAP CALU PFN1 FLNA SELP PPIA
REACTOME_REACT_6253 ERCC2 ERCC3 TFIIA_(complex) TAF13 TAF12 TAF11 TAF10 GTF2A1 GTF2A2 HIV-1_transcription_complex_(complex) GTF2E1 GTF2E2 RNA_Polymerase_II_(unphosphorylated)_TFIIF_complex_(complex) GTF2B HIV-1_transcription_complex_containing_11_nucleotide_long_transcript_(complex) TAF4B TFIIE_(complex) HIV-1_transcription_complex_containing_4-9_nucleotide_long_transcript_(complex) HIV-1_transcription_complex_containing_transcript_to_+30_(complex) HIV-1_transcription_complex_containing_3_nucleotide_long_transcript_(complex) GTF2H3 GTF2H2 GTF2H1 RNA_Polymerase_II_holoenzyme_complex_(unphosphorylated)_(complex) GTF2H4 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L MNAT1 POLR2I POLR2H POLR2K POLR2J TAF6 TAF5 TAF4 GTF2F1 TAF1 GTF2F2 TBP TAF9 TFIIH_(complex) TFIID_(complex) HIV-1_transcription_complex_containing_9_nucleotide_long_transcript_(complex) CDK7 CAK_(complex) HIV-1_transcription_complex_containing_4_nucleotide_long_transcript_(complex) CCNH
REACTOME_REACT_18407 Ligand_GPCR_complexes_that_activate_G12/13_Heterotrimeric_G-protein_G12/13_(inactive)._(complex) G-protein_G12/G13_(active)_(complex) RhoA-B-C_(family) VAV1_effectors_(family) ROCK_(family) RHOB G-protein_alpha_(12/13)_LARG_(complex) G-protein_alpha_(12/13)_GTP_(complex) GNG8 RHOA PLXNB1 PIK3CA PI3K_alpha_(complex) RAC1 GNG10 GNG11 GNG12 ARHGEF1 PIK3R3 PIK3R2 PIK3R1 GNG2 GNGT2 G-protein_gamma_subunit_(family) PI3K-regulatory_subunits_(family) Activated_ROCK_RhoA/B/C_GTP_(complex) GNG3 ARHGEF12 RAC2 Ligand_GPCR_complexes_that_activate_G12/13_Heterotrimeric_G-protein_G12/13_(active)._(complex) Activated_Rac1_PI3K_alpha_(complex) GNB5 GNB4 GNB1 G-protein_beta-gamma_complex_(complex) GNB3 GNB2 VAV1_Rho/Rac_effectors_GTP_(complex) G-protein_G12/G13_(inactive)_(complex) RHOC Ligand_GPCR_complexes_that_activate_G12/13_(complex) G-protein_alpha_(13)_GTP_(complex) RHOG G-protein_alpha_(12/13)_GDP_(complex) ROCK1 ROCK2 G-protein_alpha_(12/13)_LARG_Plexin_B1_(complex) GNG7 GNG4 GNG5 G-protein_beta_subunit_(family) GNA13 GNGT1 RhoA/B/C_GTP_(complex) GNG13 G13-activated_p115-RhoGEF_(complex) CDC42
REACTOME_REACT_70 POLA2 POLA1 Processive_complex_Okazaki_fragment_Flap_RPA_heterotrimer_(complex) RPA3 Processive_complex_Okazaki_fragment_Flap_(complex) RNA_primer-DNA_primer_origin_duplex_PCNA_(complex) RPA_heterotrimer_(complex) DNA2 DNA_Pol_alpha_primase_(complex) POLD1 POLD2 POLD3 POLD4 Processive_complex_Okazaki_fragments_Remaining_Flap_(complex) PRIM1 PCNA PRIM2 Processive_complex_nicked_DNA_from_adjacent_Okazaki_fragments_(complex) RNA_primer-DNA_primer_origin_duplex_(complex) PCNA_homotrimer_(complex) RNA_primer_origin_duplex_DNA_polymerase_alpha_primase_complex_(complex) Processive_complex_(complex) Processive_complex_Okazaki_fragment_Flap_RPA_heterotrimer_dna2_(complex) RPA1 DNA_Polymerase_delta_tetramer_(complex) Processive_complex_Okazaki_fragment_complex_(complex) RPA2
PID_PKA_mediated_phosphorylation_of_CREB phospho-CREB_dimer_(complex) PKA_catalytic_subunit CREB1
REACTOME_REACT_118563 viral_DNA_with_3prime_sticky_ends_(complex) TREX1 TREX1_viral_DNA_(complex) TREX1_dimer_(complex)
BIOCYC_LCYSDEG-PWY CTH
REACTOME_REACT_115831 ISG15_NEDD4_(complex) ISGylated_PP2CB_(complex) E2_congugating_enzymes_(family) ISGylated_IRF3_(complex) UBE2L6 PIN1 ISGylated_E2_conjugating_enzymes_(complex) ISGylated_NS1_(complex) NS1_homodimer_Importin_(complex) p-IRF3_dimer_PIN1_(complex) NEDD4 ISGylated_Filamin_B_(complex) UniProt_P03496_NS ISG15 UBA52 TRIM25 NS1_Homodimer_(complex) RPS27A p-IRF3_p-IRF3_(complex) ARIH1 ISG15_UBCH8_(complex) monoubiquitinated_N-myristoyl_GAG_(P12493)_protein_(complex) UBE2E1 UBA7 HERC5 ISGylated_4EHP_mRNA_(complex) ISGylated_host_proteins_(complex) PPM1B IRF3 EIF4E2 UBE2N ISG15_E3_ligases_(family) ISGylated_4EHP_(complex) UniProt_P12493_gag ISG15_UBCH8_ISG15_E3_ligase_(complex) UBB UBC Activated_ISG15_(complex) FLNB ubiquitin_(family)
REACTOME_REACT_6274 Cap_Binding_Complex_(CBC)_(complex) NCBP1 NCBP2 HIV-1_capped_pre-mRNA_CBC_RNA_Pol_II_(phosphorylated)_complex_(complex) NELFA CTDP1 RNA_Pol_II_(hypophosphorylated)_capped_pre-mRNA_complex_(complex) SUPT5H RNA_Pol_II_(hypophosphorylated)_complex_bound_to_DSIF_protein_(complex) NELFB RNA_Polymerase_II_holoenzyme_complex_(phosphorylated)_(complex) POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L NELFE POLR2I POLR2H POLR2K POLR2J GTF2F1 Aborted_HIV-1_early_elongation_complex_(complex) NELFCD GTF2F2 RNA_Polymerase_II_holoenzyme_complex_(hypophosphorylated)_TFIIF_complex_(complex) RNA_polymerase_II_(phosphorylated)_TFIIF_complex_(complex) NELF_complex_(complex) SUPT4H1 DSIF_NELF_early_elongation_complex_(complex) DSIF_complex_(complex) HIV-1_Polymerase_II_(phosphorylated)_TFIIF_capped_pre-mRNA_(complex)
BIOCYC_THREONINE-DEG2-PWY GCAT
REACTOME_REACT_11208 COPZ1 COPA Coatomer_Arf1-GTP_GAP_Complex_(complex) COPE ARF1 COPG1 ARCN1 Coatomer_(complex) ARFGAP1 COPB1 ARF1/GTP_(complex) COPB2 ARF1/GDP_(complex) Coatomer_Arf1-GTP_Complex_(complex)
PID_The_role_of_Nef_in_HIV_1_replication_and_disease_pathogenesis myristoylated_Nef_Protein_(numerous_variants)
REACTOME_REACT_6964 TSC1_TSC2_(complex) TSC1_p-S1387-TSC2_(complex) Rheb_GDP_(complex) RHEB TSC2 TSC1
BIOCYC_PWY-5972 ACSL3 ACSL1 ACSL4 ACSL5 ELOVL6 ACSBG1 ACSBG2 ELOVL1 ACOT7 ACOT4 SLC27A2 ACOT2 ACOT1
PID_Arachidonate_production_from_DAG Diacylglycerol_lipase MGLL
PANTHER_P00010 Complex_(BLNK/vav)_(complex) GSR Calmodulin Complex_(Ras/GTP)_(complex) DHFR I_kappa_B mIgM CYB5R3 Grb2 CD45_(complex) ERK Complex_(fos/jun)_(complex) Complex_(Ras/Raf/_MEK/GTP)_(complex) fos Syk PI3K Ig-beta SOS Complex_(CD19/Lyn/_PI3K)_(complex) PKC Complex_(PKC/DAG)_(complex) Complex_(SHP-1/CD22)_(complex) Complex_(Rac/GTP)_(complex) IKK Raf PLC_gamma2 vav BLNK IP3R Complex_(Ras/GDP_)_(complex) Calcineurin Ig-alpha MEKK Complex_(mIgM/Ig-alpha/_Ig-beta/Blk/_Btk/Lyn/_Syk)_(complex) jun p38 Complex_(BLNK/PLC_gamma2/_Btk/Grb2/_SOS)_(complex) Complex_(Ras/GTP/_Raf)_(complex) SHP-1 Complex_(mIgM/Ig-alpha/_Ig-beta)_(complex) Complex_(Calmodulin/Ca++/_Ca++)_(complex) Rac Complex_(BLNK/Btk/_PLC_gamma2/Grb2/_SOS)_(complex) MEK MT-CO1 Ras Jnk Btk CD19
PID_AKT_mediated_inactivation_of_FOXO1A AKT1 FOXO1
REACTOME_REACT_2100 Dynein_(DLC2)_on_microtubules_(complex) BMF DYNLL2
REACTOME_REACT_1231 A_to_I_edited_RNA_Editosome_(ADAR1)_complex_(complex) ADAR2_homodimer_(complex) A_to_I_edited_RNA_Editosome_(ADAR2)_complex_(complex) ADAR ADARB1 ADAR1_homodimer_(complex)
REACTOME_REACT_160089 UBC Ub-DLL/JAG_NOTCH1_HD_domain_mutants_(complex) JAG2_NOTCH1_HD_domain_mutants_(complex) DLL/JAG_NOTCH1_HD_domain_mutants_(complex) NOTCH1_heterodimerization_domain_mutants_(complex) RPS27A NOTCH1 DLL1 JAG1_NOTCH1_HD_domain_mutants_(complex) DLL4 UBB DLL1_NOTCH1_HD_domain_mutants_(complex) JAG2 JAG1 DLL4_NOTCH1_HD_domain_mutants_(complex) ubiquitin_(family)
BIOCYC_MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS dolichyl-phosphate_mannosyltransferase_polypeptide_2__regulatory_subunit ALG8 DPAGT1 Dolichyl-phosphate_mannosyltransferase_(complex) ALG3 ALG1 ALG6 ALG5 ALG13 DPM3 DPM1
BIOCYC_PWY0-162 NME5 NME6 NME7 UMPS CTPS2 CTPS1 NME3 CMPK1 CMPK2 NME1 NME2P1 CAD NME2 nucleoside_diphosphate_kinase_(complex) CAD_protein_(complex)
BIOCYC_GLUTAMINDEG-PWY GLS ASNS GLS2 glutaminase__kidney_isoform_(complex)
REACTOME_REACT_160194 RBP4_mutants_(family) OPN1SW OPN1SW/OPN1LW_(family) TTR_tetramer_(complex) RLBP1 STRA6 STRA6_mutants_(family) RBP1_atROL_(complex) OPN1MW2 RLBP1_11cRAL_(complex) RBP1 OPN1SW/OPN1MW_(family) RBP4 RLBP1_11cROL_(complex) OPN1LW OPN1MW/OPN1LW_(family) TTR TTR_RBP4_atROL_STRA6_mutants_(complex)
REACTOME_REACT_111168 HLA-C HLA-B HLA-A MHC_Class_I_(family) HLA-G Class_I_MHC_B2M_(complex) HLA-E HLA-F B2M Class_I_MHC_heavy_chain_(MHC_HC)_(family) Beta-2-microglobulin_class_I_MHC_heavy_chain_Complex_(complex) Antigen_peptide_bound_class_I_MHC_(complex)
PID_Peptide_chain_elongation eEF1A_GDP_(complex) FAU 80S_aminoacyl_tRNA_mRNA_eEF1A_GTP_(complex) RPL14 RPL15 RPL17 RPL10 RPL11 RPL12 RPL13 RPL18 RPL19 40S_ribosomal_complex_(complex) UBA52 80S_ribosome_(complex) RPS3 RPL37A RPL8 RPL6 RPL7 RPL27A RPL5 RPL3 EMBL_V00589 60S_ribosomal_complex_(complex) RPL7A eEF1A_GTP_(complex) RPS9 RPS3A RPL9P7 eEF1A_GTP_aminoacyl-tRNA_complex_(complex) eEF2_GTP_(complex) Elongation_complex_with_growing_peptide_chain_(complex) RPLP2 RPLP1 RPLP0 RPL18A RPL35A RPS15A RPS7 RPS6 RPS5 RPS27A RPS2 RPL41 RPS8 RPS4Y1 RPS15 eEF2_GDP_(complex) RPL13A 80S_Met-tRNAi_mRNA_(complex) RPL4 RPS26 RPS27 RPS24 RPS25 RPS23 RPS20 RPS21 RPS28 RPS29 RPS4X EMBL_J01866 RPSA 80S_Ribosome_mRNA_peptidyl-tRNA_with_elongating_peptide_(complex) RPL10A EMBL_M11167 Ceruloplasmin_mRNA RPS13 RPS12 RPS11 RPS10 RPS17 RPS16 RPL23A RPS14 EEF1A1 RPS19 RPS18 RPL3L EMBL_X03205 RPL29 RPL28 RPL24 RPL27 RPL26 RPL21 RPL23 RPL22 RPL26L1 RPL38 RPL39 RPL36 RPL37 RPL34 RPL35 RPL32 RPL30 RPL31 RPL36A EEF2
PID_Collagen_adhesion_via_GPVI FCER1G GPVI_FceRI_gamma_FYN_LYN_Collagen_I_(complex) FYN FceRI_gamma_dimer_(complex) GPVI_FceRI_gamma_FYN_LYN_(complex) GP_VI___FceRI_gamma_dimer_(complex) GP6 LYN
PID_syndecan_pathway SDC1 SDC2 SDC3 SDC4 Syndecan_Family
PID_Processive_synthesis_on_the_lagging_strand PCNA POLA2 POLA1 RNA_primer-DNA_primer_origin_duplex_PCNA_(complex) DNA_Pol_alpha_primase_(complex) Processive_complex_Okazaki_fragment_complex_(complex) POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 PCNA_homotrimer_(complex) LIG1 PRIM2 RNA_primer_origin_duplex_DNA_polymerase_alpha_primase_complex_(complex) POLD4 Processive_complex_(complex) POLD2 RNA_primer-DNA_primer_origin_duplex_(complex) Processive_complex_Okazaki_fragment_Flap_(complex) PRIM1
PID_arenrf2pathway Nrf2/bZip_(complex) PKC NFE2L2 Small_Mafs KEAP1 bZip Nrf2/Small_Mafs_(complex)
PID_S6K1_mediated_signalling RPTOR RHEB RPS6KB1 Activated_mTORC1_(complex) MTOR MLST8 Rheb_GTP_(complex)
PID_fibrinolysispathway Fibrin_E1_(complex) fibrin F2 Thrombin/Fibrin_(complex) F_XIIIa alpha-2_antiplasmin UBE2A DD Fibrin_E2_(complex) Thrombin/Thrombin_receptor_(complex) PLAU PLAT PLG F2R carboxypeptidase_u ZFHX3 UBA1 SERPINB2 Plasminogen SERPINE1
PID_M_Phase SMC1A STAG1 RAD21 PLK1 SMC3 Cohesin_Complex_with_a_phosphorylated_SA2_Subunit_(complex) STAG2 REC8
BIOCYC_SAM-PWY MAT2A MAT1A MAT2B
REACTOME_REACT_120916 HIF3A TCEB2 TCEB1 RPS27A UBE2D2 UBE2D3 HIF1A UBE2D1 VHL UBIQ_HUMAN_(family) E2_Conjugating_Enzymes_UbcH5a/b/c_Ubiquitin_Complex_(complex) VBC_complex_(complex) hydroxyPro-HIF-alpha_VHL_EloB/C_CUL2_RBX1_(complex) UbcH5a/b/c_(family) CUL2 Ubiquitinated_HIF-alpha_VHL_EloB/C_CUL2_RBX1_(complex) ECV_E3_ligase_complex_(complex) Ubiquitinated_HIF-alpha_(complex) HIF-alpha_with_Hydroxylated_Proline_(family) VHL_EloB/C_CUL2_RBX1_(complex) UbcH5a/b/c_Ubiquitin_(complex) EPAS1 ubiquitin_(family) UBA52 UBB UBC RBX1 UbcH5a_b_c_(family)
PID_APC_Cdc20_mediated_degradation_of_Nek2A MAD2L1 Multiubiquitinated_Nek2A_(complex) BUB1B phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) UBE2D1 CDC16 ANAPC11 ANAPC10 MCC_APC/C_complex_(complex) BUB3 UBE2E1 Nek2A_MCC_APC/C_complex_(complex) ANAPC1 NEK2 ANAPC2 ANAPC5 ANAPC4 ANAPC7 CDC27 CDC26 UBE2C CDC23 CDC20 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 hBUBR1_hBUB3_MAD2__CDC20_complex_(complex)
REACTOME_REACT_12389 NOS3 eNOS_Caveolin-1_NOSTRIN_Dynamin-2_(complex) eNOS_Caveolin-1_NOSTRIN_complex_(complex) eNOS_Caveolin-1_NOSTRIN_dynamin-2_N-WASP_(complex) NOSTRIN_homotrimer_(complex) WASL DNM2 palmitoylated__myristoylated_eNOS_dimer_(complex) NOSTRIN eNOS_Caveolin-1_(complex) CAV1
BIOCYC_PWY-6535 ALDH5A1 GABA-T_(complex) NAD-dependent_succinate_semialdehyde_dehydrogenase_(complex) ABAT
REACTOME_REACT_13638 NGF RAC1_GDP_(complex) BCL2L11 RAC1 MAGED1 mature_beta-NGF_homodimer_(complex) NGF_p75NTR_NRAGE_(complex) mature_NGF_homodimer_p75NTR_(complex) BAD RAC1_GTP_(complex) AATF NGFR NGF_ligand_p75NTR_NRAGE_CHE1_(complex) MAPK8
REACTOME_REACT_13696 NF-kB_complex_(complex) NGF Phospho-IKK-beta_homdimer_(complex) mature_NGF_homodimer_p75NTR_(complex) mature_beta-NGF_homodimer_(complex) TRAF6 NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_Phospho-IKK-beta_(complex) ubiquitin_(family) NFKBIA UBA52 IKBKB SQSTM1 IkB(alpha)_NF-kB_complex_(complex) RPS27A NGFR UBB UBC NFKB1 RELA IRAK1 Ubiquitinated_phospho-IkB_(complex)
REACTOME_REACT_1385 POLA2 POLA1 Processive_complex_Okazaki_fragment_Flap_RPA_heterotrimer_(complex) RPA3 Processive_complex_Okazaki_fragment_Flap_(complex) RNA_primer-DNA_primer_origin_duplex_PCNA_(complex) RPA_heterotrimer_(complex) DNA2 POLD3 POLD4 Processive_complex_Okazaki_fragments_Remaining_Flap_(complex) PRIM1 PCNA DNA_polymerase_alpha_primase_(complex) PRIM2 Processive_complex_nicked_DNA_from_adjacent_Okazaki_fragments_(complex) RNA_primer-DNA_primer_origin_duplex_(complex) PCNA_homotrimer_(complex) RNA_primer_origin_duplex_DNA_polymerase_alpha_primase_complex_(complex) Processive_complex_(complex) Processive_complex_Okazaki_fragment_Flap_RPA_heterotrimer_dna2_(complex) RPA1 DNA_Polymerase_delta_tetramer_(complex) Processive_complex_Okazaki_fragment_complex_(complex) RPA2
PID_Bile_salt_and_organic_anion_SLC_transporters MATE1/2 SLC10A6
BIOCYC_PWY-7205 NME5 NME6 NME7 NME1 NME2 NME3 NME2P1 nucleoside_diphosphate_kinase_(complex)
REACTOME_REACT_6235 EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 EMBL_AF389119_H1N1_Genomic_RNA_Segment_5 EMBL_AF389120_H1N1_Genomic_RNA_Segment_6 Segment_1_RNP_(complex) matrix_associated_complete_RNP_complex_(complex) palmitylated_M2_Tetramer_(complex) Glycosylated__palmitylated_and_folded_HA_trimer_(complex) UniProt_P03485_M EMBL_AF389117_H1N1_Genomic_RNA_Segment_3 Segment_3_RNP_(complex) UniProt_P03431_PB1 Segment_5_RNP_(complex) UniProt_P03508_NS UniProt_P03428_PB2 EMBL_AF389122_H1N1_Genomic_RNA_Segment_8 UniProt_P03466_NP UniProt_P03452_HA UniProt_P03433_PA Segment_4_RNP_(complex) EMBL_AF389115_H1N1_Genomic_RNA_Segment_1 Segment_6_RNP_(complex) Segment_7_RNP_(complex) Segment_8_RNP_(complex) EMBL_AF389118_H1N1_Genomic_RNA_Segment_4 UniProt_P06821_M Gycosylated_NA_Tetramer_(complex) Segment_2_RNP_(complex) RNP_pre-assembly_complex_(complex) EMBL_AF389116_H1N1_Genomic_RNA_Segment_2 UniProt_P03468_NA
PID_Resolution_of_AP_sites_via_the_multiple_nucleotide_patch_replacement_pathway POLD2 APEX1 POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 POLD4 LIG1 Ligated_patch-repaired_DNA_(complex)
PID_FGFR_ligand_binding_and_activation GRB2 SDC2 Activated_FGFR_complexed_with_phosphorylated_FRS2__GRB2_and_CBL_(complex) CBL Phospho-FRS2
REACTOME_REACT_12524 MAP2K2 MAPK1 phospho-ERK-2_dimer_(complex) MEK2_ERK-2_(complex) phospho-ERK-2_MEK2_(complex)
REACTOME_REACT_570 phospho-IRS_(family) activated_insulin_receptor_(complex) Insulin_(complex) phospho-IRS_activated_insulin_receptor_(complex) IRS1 IRS2 INS INSR DOK1 IRS_activated_insulin_receptor_(complex) IRS_(family) phospho-insulin_receptor_(complex)
PID_Activation_of_the_pre_replicative_complex POLA2 POLA1 Orc2_associated_with_MCM8_(complex) active_pre-replicative_complex_(complex) POLE RPA_Cdc45_CDK_DDK_Mcm10_pre-replicative_complex_(complex) CDC6 CDC7 CDT1_CDC6_ORC_origin_complex_(complex) CDC45 phosphorylated_Mcm2-7_complex_(complex) CDT1 DNA_Pol_alpha_primase_(complex) PRIM1 Mcm10_pre-replicative_complex_(complex) DDK_(complex) DNA_polymerase_alpha_primase_DNA_polymerase_alpha_origin_complex_(complex) CDC6_ORC_origin_complex_(complex) DNA_polymerase_epsilon_(complex) MCM10 DNA_polymerase_epsilon_origin_complex_(complex) ORC6 ORC4 ORC5 ORC2 ORC3 ORC1 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2 Mcm2-7_complex_(complex) MCM8 pre-replicative_complex_(complex) RPA4 Cdc45_CDK_DDK_Mcm10_pre-replicative_complex_(complex) RPA1 RPA3 RPA2 CDK2 Mcm10_active_pre-replicative_complex_(complex) DBF4 POLE2 CDK_DDK_Mcm10_pre-replicative_complex_(complex) PRIM2 ORC_origin_(complex) RFA_(complex) CDK_(complex)
REACTOME_REACT_118656 IKKA_IKKB_NEMO_(complex) Inhibitor_of_KappaB_kinase_(IKK)_Complex_(complex) RPS27A IKBKB CARMA1_oligomer_(complex) IKBKG Activated_PKC_beta_(complex) SCF-beta-TrCp1_or_SCF-beta-TrCP2_(complex) MAP3K7 NF-kappaB_p-IkB_SCF-betaTrCP_(complex) CARMA1_BCL10_MALT1_TAK1_IKK_(complex) MALT1 NF-kappaB_p50/p65/c-Rel_Dimer_(complex) CARD11 PRKCB CHUK NF-kappa-B_(p50__p65__c-Rel)_Ubiquitinated_p-IKB_(complex) p-CARMA1_Oligomer_(complex) BCL10 NF-kappa-B_p50/_p65/c-Rel_p-IKB_(complex) CARMA1_MALT1_BCL10_(complex) UBB UBC NF-kappa-B_p50_/p65_/c-Rel_IKB_(complex) ubiquitin_(family)
PID_Attachment_of_GPI_anchor_to_uPAR PGAP1 GPI_transamidase_(complex) PLAUR PIGK PIGS PIGT GPAA1 PIGU
BIOCYC_PWY-5910 IDI1 IDI2 GGPS1 farnesyl_pyrophosphate_synthetase_FPP_synthetase_FPS_farnesyl_diphosphate_synthetase <i>E</i>-farnesyl_diphosphate_synthase_(complex) HADHB mevalonate_kinase_(complex) ACAT1 ACAT2 mitochondrial_acetyl-CoA_acetyltransferase_(complex) cytosolic_acetyl-CoA_acetyltransferase_(complex) HMGCS1 HMGCS2 hydroxymethylglutaryl-CoA_synthase_(complex) 3-hydroxy-3-methylglutaryl-coenzyme_A_reductase_(complex) geranylgeranyl_pyrophosphate_synthetase_(complex) MVD HMGCR MVK FDPS PMVK diphosphomevalonate_decarboxylase_(complex)
PID_Generic_Transcription_Pathway MED20 MED23 MED25 MED24 MED27 MED26 DRIP_coactivator_complex_(complex) MED1 MED6 MED7 MED4 MED8 MED10 MED12 MED13 MED14 MED15 MED16 MED17 MED30 MED31 ARC_coactivator_complex_(complex) TRAP_coactivator_complex_(complex) CCNC CDK8
PID_RNA_Polymerase_III_Transcription_Termination NFIC NFIB NFIA POLR3F RNA_Polymerase_III_Holoenzyme_(complex) SSB Paused_RNA_Polymerase_III_Transcription_Complex_(complex) POLR2E POLR3D POLR2F POLR3B POLR3H POLR3A POLR2L POLR3E NFIX POLR2H POLR2K LZTS1
REACTOME_REACT_118764 IRF3 p-T_4S-IRF3_p-T_4S-IRF3_(complex) TBK1 ZBP1 IRF3_IRF3_phosphorylated_(complex) dsDNA_ZBP1_pS-172-TBK_IRF3_(complex) dsDNA_ZBP1_pS-172-TBK1_(complex) dsDNA_ZBP1_(complex) ZBP1_ZBP1_(complex)
REACTOME_REACT_115697 STAT5_(family) PRLR_ligands_p(S349)-PRLR_JAK2_dimer_(complex) p-STAT5A/B_(family) PRLR_JAK2_(complex) PRLR_ligands_Activated_PRLR_JAK2_dimer_SH2B1_beta_(complex) p(Y611)-PRLR_p(Y1007)-JAK2_dimer_(complex) PRLR_ligands_p(Y611)-PRLR_p(Y1007)-JAK2_dimer_p-SHP2_(complex) SKP1 PRLR STAT5A p(S349)-PRLR_JAK2_dimer_(complex) JAK2 PRLR_ligands_p(S349)-_PRLR_JAK2_dimer_SCF_beta-TrCP_complex_(complex) CUL1 PRLR_ligands_Activated_PRLR_JAK2_dimer_(complex) beta-TrCP_Skp1_Cul1_Rbx1_(complex) p(S349)-PRLR_JAK2_(complex) PRLR_ligands_p(Y611)-PRLR_p(Y1007)-JAK2_dimer_(complex) Activated_PRLR_JAK2_(complex) p(Y611)-PRLR_p(Y1007)-JAK2_(complex) PRLR_ligands_p(Y611)-PRLR_p(Y1007)-JAK2_dimer_p-STAT5_(complex) Activated_cytokine-like_hormone_receptors__p(Y1007)-JAK2_(complex) SH2B1 PRLR_JAK2_dimer_(complex) Activated_cytokine-like_hormone_receptors_(complex) PRLR_ligands_p(Y611)-PRLR_p(Y1007)-JAK2_dimer_SHP2_(complex) PRLR_ligands_PRLR_JAK2_dimer_(complex) PTPN11 BTRC STAT5B Activated_PRLR_JAK2_dimer_(complex) PRLR_ligands_p(Y611)-PRLR_p(Y1007)-JAK2_STAT5_(complex) RBX1
BIOCYC_PWY-6756 MTAP_(complex)
PID_Intrinsic_Pathway factor_XIIa_C1Inh_(complex) factor_VIIIa_(complex) prekallikrein_high_molecular_weight_kininogen_C1q_binding_protein_tetramer_(complex) prolylcarboxypeptidase_dimer_(complex) SERPING1 activated_high_molecular_weight_kininogen_(complex) alpha2-macroglobulin_(complex) factor_VIII_(complex) A2M factor_VIIIa_factor_IXa_(complex) factor_XIa_GPIb_GPIX_GPV_complex_(complex) GP1BA kallikrein_(complex) C1QBP GP1BB factor_XI_GPIb_GPIX_GPV_complex_(complex) factor_XIa_(complex) factor_IXa_(complex) GP9 GP5 factor_XIIa_(complex) factor_Xa_(complex) von_Willibrand_factor_multimer_(complex) kallikrein_C1Inh_(complex) activated_kininogen_C1q_binding_protein_tetramer_(complex) platelet_glycoprotein_Ib_heterodimer_(complex) plasma_thromboplastin_antecedent_(complex) KLKB1 kallikrein_high_molecular_weight_kininogen_C1q_binding_protein_tetramer_(complex) C1q_binding_protein_tetramer_(complex) high_molecular_weight_kininogen_C1q_binding_protein_tetramer_(complex) F12 Activated_thrombin_(factor_IIa)_(complex) F10 F11 F2 platelet_glycoprotein_Ib-IX-V_complex_(complex) F8 F9 KNG1 kallikrein_alpha2-macroglobulin_(complex) factor_VIII_von_Willebrand_factor_multimer_(complex) VWF PRCP
PID_Glutathione_conjugation Cytosolic_GST Cytosolic_GST_homodimer_(complex)
REACTOME_REACT_21368 K63-linked_poly-Ub-p-3S_3T-IRAK1_TRAF6_(complex) p-Pellino-1_2_(3)_(family) PELI1 TRAF6 PELI3 PELI2 Inhibitor_of_KappaB_kinase_(IKK)_Complex_(complex) TRAF6_hp-IRAK1_(complex) CHUK IKBKB TRAF6-regulated_IKK_activator_1_(complex) IKBKG UBE2V1 TRAF6_K63-linked_polyUb_p-IRAK1_IKK_complex_(complex) TRAF6_hp-IRAK1_Pellino_(complex) p-Pellino_hp-IRAK1_TRAF6_(complex) IRAK1 UBE2N
PID_AKT_phosphorylates_targets_in_the_nucleus AKT1 NR4A1 CREB1 RPS6KB2
BIOCYC_COA-PWY PPCDC COASY PPCS
Pathway_a8b1180fa007e25d770d2404e0e39e2b.owl EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 EMBL_AF389119_H1N1_Genomic_RNA_Segment_5 EMBL_AF389120_H1N1_Genomic_RNA_Segment_6 Ribonucleoprotein_(RNP)_Complex_(complex) Influenza_A_Viral_Envelope_(complex) palmitylated_M2_Tetramer_(complex) UniProt_P03485_M EMBL_AF389117_H1N1_Genomic_RNA_Segment_3 UniProt_P03466_NP UniProt_P03431_PB1 UniProt_P03508_NS UniProt_P03428_PB2 EMBL_AF389122_H1N1_Genomic_RNA_Segment_8 Influenza_A_Viral_Particle_(complex) UniProt_P03452_HA UniProt_P03433_PA EMBL_AF389115_H1N1_Genomic_RNA_Segment_1 EMBL_AF389118_H1N1_Genomic_RNA_Segment_4 UniProt_P06821_M Gycosylated_NA_Tetramer_(complex) EMBL_AF389116_H1N1_Genomic_RNA_Segment_2 UniProt_P03468_NA Cleaved_Trimeric_palmitylated_HA_(complex)
REACTOME_REACT_9515 FGFR1OP2 GAB2 Activated_FGFR1_fusion_mutants_p-PLCgamma_(complex) Activated_FGFR1_fusion_mutants_PLC-gamma_(complex) MYO18A PLCG1 BCR-p-FGFR1_fusion_mutant_dimer_(complex) GRB2_GAB2_(complex) CPSF6 pY177-BCR-p-FGFR1_fusion_mutant_dimer_(complex) BCR STAT3 STAT1 PIK3CA FGFR1_fusion_mutant_dimers_(complex) PIK3R1 GRB2_pY-GAB2_(complex) ZMYM2 pY177-BCR-pY-FGFR1_mutant_GRB2_p-GAB2_(complex) TRIM24 p-FGFR1_fusion_mutant_dimers_(complex) FGFR1_fusion_mutant_dimers_TKIs_(complex) CUX1 FGFR1OP p-FGFR1_fusion_mutant_dimers_PIK3R1_(complex) STAT1_3_(family) LRRFIP1 p-Y177-BCR-pY-FGFR1_mutant_GRB2_p-GAB2_PIK3R1_(complex) pY177-BCR1-p-FGFR1_mutant_GRB2_GAB2_(complex) pY177-BCR-pY-FGFR1_mutant_GRB2_p-GAB1_PI3K_(complex) p-FGFR1_mutant_fusions_PI3K_(complex) STAT5B STAT5A GRB2 pY-STAT1_3_(family) CNTRL FGFR1_fusion_mutants_(family) p-STAT5A/B_(family)
Pathway_bea84700f9863e40740283e0699f9b64.owl CYP4F8 CYP4F2 TBXAS1 PTGIS
PID_mRNA_Splicing___Minor_Pathway Cap_Binding_Complex_(CBC)_(complex) NCBP1 NCBP2 snRNP_Sm_core_complex_(complex) SF3B5 SF3B4 SF3B1 SF3B3 SF3B2 PRPF8 POLR2L TXNL4A U12_snRNP_(complex) ATAC_C_Complex_with_lariat_containing_5prime-end_cleaved_mRNA_(complex) U4_ATAC_U5_U6_ATAC_Complex_(complex) PRPF6 SNRNP200 SRSF7 SRSF6 SRSF1 RNA_Polymerase_II_(unphosphorylated)_TFIIF_complex_(complex) SRSF2 SNRPF SNRPD3 SNRPG EFTUD2 U5_snRNP_(complex) EMBL_X04293_U5_snRNA ATAC_A_Complex_(complex) SNRPE NHP2L1 U6_ATAC_snRNP_(complex) RNA_Polymerase_II_holoenzyme_complex_(unphosphorylated)_(complex) U4_ATAC_snRNP_U6_ATAC_snRNP_(complex) LSM2 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B SNRPB ATAC_B_Complex_(complex) POLR2I POLR2H POLR2K POLR2J DDX23 SNRNP40 Splicing_Factor_3B_(complex) GTF2F1 SNRPD2 SNRPD1 GTF2F2 SF3B14 U4_ATAC_snRNP_(complex) ATAC_C_Complex_(complex) capped__methylated_pre-mRNA_CBC_Complex_(complex) U11_snRNP_(complex)
PID_CDC6_association_with_the_ORC_origin_complex E2F_transcription_factors Orc2_associated_with_MCM8_(complex) ORC6 ORC4 ORC5 ORC2 ORC3 ORC1 CDC6 ORC_origin_(complex) CDC6_ORC_origin_complex_(complex) MCM8
PID_DARPP_32_events Phosphorylated_(T34)_DARPP-32_PP1A_(complex) PPP1R1B CALM3 PPP3R1 PPP1CA PP2A-ABdeltaC_complex_(complex) PDE_4 PP1A(Fe_and_Mn_cofactors)_(complex) Active_Calmodulin_(complex) CDK5 Phosphorylated_(Thr75)_DARPP-32_PKA_(complex) PP2B_complex_(complex) PRKACA PDE4B PP2B_catalytic_(Fe3+__Zn2+)_Active_Calmodulin_(complex) PKA_regulatory_subunit cAMP_PKA_regulatory_subunit_(complex)
REACTOME_REACT_23947 STX1A SNAP25 VAMP2 SYN3 SYT1 Docked_serotonin_loaded_synaptic_vesicle_(complex) SNARE_Complex_(complex) STXBP1 CPLX1 Synapsin_(family) RAB3A Serotonin_loaded_synaptic_vesicle_(complex) SLC18A2 SYN2 RIMS1 SYN1
PID_Chylomicron_mediated_lipid_transport ApoB-48_TG_PL_complex_(complex) HSPG APOC2 APOC3 chylomicron_(complex) APOA4 APOA5 APOA1 APOA2 spherical_HDL_apoA-I_apoA-II_apoA-IV_apoC-II_apoC-III_(complex) lipoprotein_lipase_dimer_(complex) APOE APOB MTP_PDI_lipid_complex_(complex) chylomicron_remnant_(complex) mature_high-density_lipoprotein_(complex) LIPC spherical_high-density_lipoprotein_(complex) TG-depleted_chylomicron_(complex) P4HB LDLR LPL SAR1B HSPG-bound_lipoprotein_lipase_(complex) chylomicron_remnant_apoE_complex_(complex) MTTP chylomicron_remnant_apoE_LDLR_complex_(complex) LDLRAP1 nascent_chylomicron_(complex)
REACTOME_REACT_25026 dsRNA_RIG-1/MDA5_IPS-1_Ub-TRAF3_TBK1/IKKi_IRF3/IRF7_(complex) IRF3/_IRF7_(family) CBP/p300_(family) IKK_related_kinases_TBK1/IKK_epsilon_(family) IKBKE dsRNA_RIG-I/MDA5_(complex) p-T_4S-IRF3_p-T_4S-IRF3_(complex) TBK1 dsRNA_RIG-1/MDA5_IPS-1_Ub-TRAF3_TBK1/IKKi_(complex) phosphorylated_IRF3/IRF7_(family) IRF3-P_IRF7-P_(complex) IRF3-P_dimer_CBP/p300_(complex) TRAF3 TBK1/IKKi_SIKE1_(complex) SIKE1 dsRNA_RIG-I/MDA5_IPS-1_(complex) EP300 IRF3_bound_to_IFN-beta_promoter_(complex) IRF3 IRF7 IRF3_IRF3_phosphorylated_(complex) p-2S-IRF7_p-2S-IRF7_(complex) dsRNA_RIG-1/MDA5_IPS-1_Ub-TRAF3_(complex) MAVS CREBBP
REACTOME_REACT_19333 p(S27)-G_protein_alpha_(z)_GTP_(complex) G-protein_alpha_(z)_GDP_(complex) Ligand_GPCR_complexes_that_activate_Gz_(complex) Adenylate_cyclase_(Mg2+_cofactor)_(complex) Ligand_GPCR_complexes_that_activate_Gz_Heterotrimeric_G-protein_Gz_(active)_(complex) Ligand_GPCR_complexes_that_activate_Gz_Heterotrimeric_G-protein_Gz_(inactive)_(complex) GNG10 GNG11 GNG12 GNG13 Adenylate_cyclase_(family) G-protein_alpha_(z)_GTP_(complex) GNG2 G-protein_gamma_subunit_(family) Heterotrimeric_G-protein_Gz_(active)_(complex) GNB5 GNB4 GNB1 G-protein_beta-gamma_complex_(complex) GNB3 GNB2 Heterotrimeric_G-protein_Gz_(inactive)_(complex) G-protein_alpha_(z)_GTP_Adenylate_cyclase_(complex) ADCY4 ADCY6 ADCY7 ADCY1 ADCY2 ADCY3 ADCY8 ADCY9 GNAZ GNG7 GNG4 GNG5 G-protein_beta_subunit_(family) GNG3 GNGT1 GNG8
PID_Transport_of_Ribonucleoproteins_into_the_Host_Nucleus NUP88 AAAS UniProt_P03433_PA NUP133 NUP85 EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 EMBL_AF389119_H1N1_Genomic_RNA_Segment_5 EMBL_AF389120_H1N1_Genomic_RNA_Segment_6 UniProt_P03428_PB2 Ribonucleoprotein_(RNP)_Complex_(complex) RNP_Complex_Karyopherin_alpha_(complex) NUP62 SEH1L NUP98 NUP43 NUP188 EMBL_AF389117_H1N1_Genomic_RNA_Segment_3 UniProt_P03466_NP NUP214 UniProt_P03431_PB1 NUP210 RANBP2 POM121 NUP155 EMBL_AF389122_H1N1_Genomic_RNA_Segment_8 NUP107 Nup107_Complex_(complex) NUP160 KPNB1 NUP93 TPR Nup62_Complex_(complex) NUPL1 NUPL2 RNP_Karyopherin_alpha_Karyopherin_beta_complex_(complex) EMBL_AF389115_H1N1_Genomic_RNA_Segment_1 EMBL_AF389118_H1N1_Genomic_RNA_Segment_4 NUP50 NUP54 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 EMBL_AF389116_H1N1_Genomic_RNA_Segment_2 NUP153 KPNA1 NUP205 RAE1
REACTOME_REACT_163834 NFATC1 NFATC2 NFATC3 CaN-catalytic_alpha/beta_chains_(family) PPP3R1 GADS_p-Y113_Y128_Y145-SLP-76_(complex) PPP3CA/B_(family) p-5Y-LAT_p-SHC1_GRB2_SOS1_GADS_p-Y113_Y128_Y145-SLP-76_PLCG1_VAV_p-2Y-TEC_kinases_(complex) PLCG2 PLCG1 CaN_catalytic_alpha/beta_Zn++_Fe3+_CaM_Ca2+_(complex) Dephosphorylated_NFAT_(family) IP3_receptors_(family) p-5Y-LAT_p-SHC1_GRB2_SOS1_GADS_p-Y113_Y128_Y145-SLP-76_PLCG1_VAV_TEC_kinases_PIP3_(complex) GRB2_SOS1_(complex) p-5Y-LAT_p-SHC1_GRB2_SOS1_GADS_p-Y113_Y128_Y145-SLP-76_PLCG_(complex) CaN_alpha_regulatory_Ca2+_(complex) TXK p-SHC1_GRB2_SOS_(complex) CALM1 IP3_receptor_homotetramer_(complex) TEC p-5Y-LAT_p-SHC1_GRB2_SOS1_GADS_p-Y113_Y128_Y145-SLP-76_p-PLCG_(complex) GRAP2 p-4Y-PLCG_(family) Calcineurin_beta_catalytic_subunit_Fe3+_Zn2+_(complex) Dephosphorylated_NFATC1_2_3_(family) LCP2 NFAT_CaN_CaM_(complex) TEC_BTK_ITK_(TXK)_(family) p-Y223_Y551-BTK_p-Y180_Y512-ITK_p-Y206_Y519-TEC_(Y91_Y420-TXK)_(family) Active_Calmodulin_(complex) ITPR2 ITPR3 SHC1 ITPR1 Calcineurin_Calmodulin_(CaN_CaM)_(complex) p-5Y-LAT_p-SHC1_GRB2_SOS1_GADS_p-Y113_Y128_Y145-SLP-76_PLCG1_VAV_p-2Y-BTK/p-2Y-ITK_PIP3_(complex) p-5Y-LAT_p-SHC1_GRB2_SOS1_(complex) SOS1 Phospholipase_C_gamma1_and_Phospholipase_C_gamma2_(family) Calcineurin_alpha_regulatory_subunit_Calcium_(complex) VAV1 VAV3 VAV2 CaN_CaM_Ca2+_(complex) GRB2 CaN_catalytic_alpha/beta_Zn++_Fe3+_(complex) IP3_receptor_IP3_complex_(complex) LAT PPP3CA PPP3CB p-5Y-LAT_p-SHC1_GRB2_SOS1_GADS_p-Y113_Y128_Y145-SLP-76_PLCG1_VAV_p-TEC_kinases_PIP3_(complex) Calcineurin_beta_catalytic_subunit_Active_Calmodulin_(complex) p-Y551-BTK_p-Y512-ITK_p-519-TEC_(p-Y420-TXK)_(family) BTK
REACTOME_REACT_12020 MAPK7
PID_S6K1_signalling EEF2K RPS6 EIF4G1 RPS6KB1 EIF4B
PID_hivnefpathway2 APAF-1/Caspase_9_(complex) BAG4 BIRC3 CYCS RIPK1 TNF_R/Caspase_2/TNF/FADD/TRADD/RIP/cIAP/TRAF1/TRAF2/ASK1/RAIDD_(complex) MAP2K7 TNF_R Caspase_8/Caspase_8/Caspase_8/Caspase_8_(complex) CRADD HIV-1_NEF DAXX FAS BID TRADD MAP3K5 CFLAR FADD MAPK8 FAS/FADD/DAXX/ASK1/Caspase_8/Caspase_8/FAS_L_(complex) APAF1 TRAF1 TRAF2 CHUK TNF FASLG TNF/TNF_R/SODD_(complex) IAP CASP6 CASP7 CASP2 CASP3 CASP8 CASP9 MAP3K14 BCL2
PID_Inhibition_of_Insulin_Secretion_by_Adrenaline_Noradrenaline G-protein_alpha_i/o_GDP_Complex_(complex) Adrenaline/Noradrenaline_Alpha-2A/2C_Adrenergic_Receptor_Complex_(complex) Alpha-2A/2C_Adrenergic_Receptors Adenylate_cyclase_type_V_or_VI__G-protein_beta_gamma_Complex_(complex) G-protein_i/o_alpha_GTP_G-protein_beta_G-protein_gamma_Complex_(complex) G-protein_beta_gamma_Complex_(candidates)_(complex) G-protein_alpha_i/o_GTP_Complex_(complex) G-protein_i/o_alpha_GDP_G-protein_beta_G-protein_gamma_Complex_(complex)
PID_Regulated_proteolysis_of_p75NTR TRAF6 gamma-secretase_complex_(complex) PSENEN NF-kB_p75NTR_ICD_TRAF6_(complex) NF-kB_complex_(complex) Presenilin_homodimer_(complex) Nicastrin ADAM_17_metalloprotease_(Zn_cofactor)_(complex) ADAM17 NFKB1 RELA Presenilin NGFR
PID_Eukaryotic_Translation_Elongation eEF1B_complex_(complex) eEF1A_GTP_(complex) EEF1A1 EEF1D eEF1A_GTP_aminoacyl-tRNA_complex_(complex) EEF1B2 EEF1G
REACTOME_REACT_9053 Cam-PDE_1_homodimer_(complex) active_Cam-PDE_1_(complex)
PID_pelp1pathway SRC PELP1/CBP_(complex) ESR1 Estrogen/ER_alpha_(complex) Estrogen/ER_alpha/PELP1/SRC_(complex) PELP1 PELP1/p300_(complex) Estrogen/ER_alpha/PELP1_(complex) EP300 CREBBP
REACTOME_REACT_11065 PPP2R1A PPP2R1B beta-catenin_Axin_GSK3_CK1alpha_APC_PP2A_FAM123B_complex_(complex) PP2A-catalytic_subunit_C_(family) CTNNB1 p-S33_S37_T41_S45-beta-catenin_Axin_GSK3_CK1alpha_APC_PP2A_FAM123B_complex_(complex) AXIN1 AMER1 p-T41_S45-beta_catenin_(family) p-S37_T41_S45-beta-catenin_(family) p-S33_S37_T41_S45-beta-catenin_(family) PP2A-subunit_A_(family) PP2A_regulatory_subunit_B56_(family) pS45-beta-catenin_Axin_GSK3_CK1alpha_APC_PP2A_FAM123B_complex_(complex) pS45-_beta-catenin_(family) p-S37_T41_S45-beta-catenin_Axin_GSK3_CK1alpha_APC_PP2A_FAM123B_complex_(complex) Axin_GSK3_CK1alpha_APC_PP2A_FAM123B_complex_(complex) APC p-T41_S45-beta-catenin_Axin_GSK3_CK1alpha_APC_PP2A_FAM123B_complex_(complex) CSNK1A1 PPP2CA PPP2CB PP2A_(complex) GSK3B PPP2R5D PPP2R5E PPP2R5A PPP2R5B PPP2R5C
PID_Formation_of_annular_gap_junctions Planar_gap_junction_plaques_associated_with_Dab2_and_Dynamin_(complex) AP2M1 planar_gap_junction_plaques_associated_with_Dab2_(complex) Clathrin_(complex) planar_gap_junction_plaques_(complex) gap_junction_plaque_(complex) Junctional_channel_(complex)
REACTOME_REACT_311 RAD23B ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 TFIIH_(complex) RPA_heterotrimer_(complex) ERCC1_XPF_complex_(complex) XPC DDB2 Incision_complex_with_3prime-incised_damaged_DNA_(complex) DDB1 XPA GTF2H3 GTF2H2 GTF2H1 GTF2H4 XPC_HR23B_complex_(complex) MNAT1 RPA1 RPA3 RPA2 CDK7 CAK_(complex) CCNH
REACTOME_REACT_75792 H2BFS SYCP1 SYNE1 Nucleosome_(complex) HIST1H4E ACD Telomere_Attachment_Plate_(complex) POT1 TEX12 FKBP6 ATR SMC1A HIST2H2BE HIST1H2AJ HIST1H2AE HIST1H2AD Central_Element_of_Synaptonemal_Complex_(complex) LMNA HIST1H2AC Transverse_Filament_of_Synaptonemal_Complex_(complex) Synaptonemal_BRCA1_Complex_(complex) TERF2IP HSPA2 Synaptonemal_BRCA1_ATR_Complex_(complex) Nucleosome_containing_Histone_H2A.x_(complex) SUN2 Histone_H2A_(family) SMC3 SUN1 H2AFB1 SYCP2 SYCE1 Extended_And_Processed_Telomere_End_Folded_Into_Higher_Order_Structure_(complex) SYCE2 HIST2H2AA3 Extended_And_Processed_Telomere_End_and_Associated_DNA_Binding_and_Packaging_Protein_Complex_Folded_Into_Higher_Order_Structure_(complex) DIDO1 BRCA1 SYCP3 Unsynapsed_Chromatin_containing_gamma-H2A.x_(complex) SMC1B Axial/Lateral_Element_of_Synaptonemal_Complex_(complex) RAD21 STAG2 STAG3 STAG1 SYNE2 Nucleosome_containing_Histone_gamma-H2A.x_(complex) HIST1H2BD HIST1H2BE Synaptonemal_Complex_(complex) HIST3H2BB HIST1H2BA HIST1H2BB HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H2BH HIST2H2AC HIST1H2BJ HIST1H2BK UBE2I Shelterin_Complex_(complex) LMNB1 Unsynapsed_Chromatin_(complex) TINF2 H2AFX H2AFZ TERF2 REC8 TERF1 Meiotic_Cohesin_Complex_(complex) HIST3H3 Histone_H2B_(family)
PID_PDE3B_signalling AKT2 PIP3_Phosphorylated_PKB_complex_(complex) PDE3B
PID_p75NTR_signals_via_NF_kB SQSTM1 NGF mature_NGF_homodimer_p75NTR_(complex) IKK-beta_homdimer_(complex) TRAF6 NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_IKK-beta_(complex) mature_beta-NGF_homodimer_(complex) IKBKB NGFR IRAK1
PID_Carnitine_synthesis trimethyllysine_dioxygenase_dimer_(complex) gamma-butyrobetaine_hydroxylase_dimer_(complex) BBOX1 ALDH9A1 4-trimethylaminobutyraldehyde_dehydrogenase_tetramer_(complex) serine_hydroxymethyltransferase_tetramer_(complex) SHMT1 TMLHE
REACTOME_REACT_89 Apaf-1_Cytochrome_C_(complex) CYCS CASP9 Cytochrome_C_Apaf-1_Caspase-9_(complex) Cleaved_Caspase-9_(complex) Cytochrome_C_Apaf-1_ATP_Procaspase-9_(complex) APAF1
BIOCYC_PWY-5189 HMBS ALAD UROS ALAS1 ALAS2 DELTA_AMINOLEVULINATE_SYNTHASE_DELTA_ALA_SYNTHETASE_ALAS_E
REACTOME_REACT_13541 DBNL ADD1 SPTAN1 VIM PLEC MAPT GAS2 GSN
REACTOME_REACT_111178 RPS27A UBC UBB HLA-B Class_I_MHC_HC_B2M_(complex) HLA-A MHC_Class_I_(family) HLA-G HLA-F HLA-E HLA-C B2M UBA52 Class_I_MHC_heavy_chain_(MHC_HC)_(family) Beta-2-microglobulin_class_I_MHC_heavy_chain_Complex_(complex) Antigen_peptide_bound_class_I_MHC_(complex) Ag_peptide_bound_class_I_MHC_(complex) ubiquitin_(family)
PID_Beta_oxidation_of_butanoyl_CoA_to_acetyl_CoA HADH ACADS short_chain_3-hydroxyacyl-CoA_dehydrogenase_homodimer_(complex) ECHS1 enoyl-CoA_hydratase_hexamer_(complex) SCAD_acyl-CoA_dehydrogenase_homotetramer_(complex)
PID_Regulation_of_pyruvate_dehydrogenase__PDH__complex PDHX PDK_isoforms PDHA1 pyruvate_dehydrogenase_complex_(complex) DLD pyruvate_dehydrogenase_E1_complex_(complex) pyruvate_dehydrogenase_E2_trimer_(complex) alpha-keto_acid_dehydrogenase_E3_homodimer_(complex) DLAT phosphorylated_pyruvate_dehydrogenase_E1_complex_(complex) phosphorylated_pyruvate_dehydrogenase_complex_(complex) pyruvate_dehydrogenase_E2_holoenzyme_(complex) PDHB alpha-keto_acid_dehydrogenase_E3_holoenzyme_(complex)
PID_vRNA_Synthesis Initiated_cRNA-vRNA_Complex_(complex) UniProt_P03428_PB2 Viral_RNA_dependent_RNA_polymerase_(complex) UniProt_P03433_PA UniProt_P03466_NP UniProt_P03431_PB1 cRNP_(complex)
PID_Enzymatic_degradation_of_Dopamine_by_monoamine_oxidase MAOA MAOA-FAD_complex_(complex) COMT
REACTOME_REACT_11046 ADORA2A ADCYAP1R1 NTRK1 NTRK2 Nerve_Growth_Factor_receptor_(family) PACAP_PACAP_type_1_receptor_(complex) ADCYAP1 Intracellular_Phosphorylated_Trk_receptors_(family) Adenosine_Adenosine_A2a_receptor_(complex)
PID_integrin_a9b1_pathway ITGA9 TGM2 CSF2RA VEGFC SAT1 PAOX alpha9/beta1_Integrin_(complex) alpha9/beta1_Integrin/VEGFD_(dimer)_(complex) ADAM12 ADAM15 F13A1 RAC1-GTP_(complex) alpha9/beta1_Integrin/ADAM15_(complex) ADAM8 alpha9/beta1_Integrin/Tenascin_C_(complex) vWF_(complex) alpha9/beta1_Integrin/ADAM12_(complex) alpha9/beta1_Integrin/vWF_(complex) alpha9/beta1_Integrin/VCAM1_(complex) PXN alpha9/beta1_Integrin/TGM2_(complex) alpha9/beta1_Integrin/Tenascin_C/Paxillin_(complex) FIGF SRC NOS2 KCNJ15 RAC1 KIR4.2/Spermine_(complex) alpha9/beta1_Integrin/ADAM2_(complex) KIR4.2/Spermidine_(complex) alpha9/beta1_Integrin/Factor_XIII_(complex) ITGB1 VCAM1 TNC alpha9/beta1_Integrin/Tenascin_C/SSAT_(complex) BCAR1 alpha9/beta1_Integrin/Osteopontin_(complex) ADAM2 FN1 alpha9/beta1_Integrin/VEGFA_(dimer)_(complex) alpha9/beta1_Integrin/GMCSF/GMR_alpha_(complex) CSF2 alpha9/beta1_Integrin/Fibronectin_(complex) SPP1 alpha9/beta1_Integrin/VEGFC_(dimer)_(complex) VEGFA alpha9/beta1_Integrin/ADAM8_(complex)
PID_Recruitment_of_repair_and_signaling_proteins_to_double_strand_breaks BRCA1 gamma_H2AX_MDC1/NFBD1_complex_at_site_of_DNA_double-strand_break_(complex) MDC1 53BP1_H2AX_complex_at_site_of_double-strand_break_(complex) ATM H2AFX gamma_H2AX-coated_DNA_double-strand_break_ends_(complex) BRCA1_53BP1_complex_at_site_of_DNA_double-strand_break_(complex) MDC1/NFBD1_gamma-H2AX_complex_(complex) TP53BP1 ATM_associated_with_DNA_double-strand_break_ends_(complex)
PID_Pyrimidine_catabolism 5prime_3prime-nucleotidase__mitochondrial_holoenzyme_(complex) 5prime-nucleotidase_cytosolic_1A_holoenzyme_(complex) NT5C_dimer_(complex) thymidine_phosphorylase_dimer_(complex) 5prime-nucleotidase__ecto_(CD73)_holoenzyme_(complex) 5prime-nucleotidase__cytosolic_III_holoenzyme_(complex) NT5C DPYD NT5E UPP1 3-ureidopropionase-Zn_complex_(complex) DPYS Dihydropyriminidase-Zn_complex_(complex) TYMP NT5C1A UPB1 NT5M UPP1_dimer_(complex) DHUdehydrogenase-Fe-2FAD-2FMN_complex_(complex)
PANTHER_P00045 Complex_(Serrate/Notch)_(complex) Complex_(Delta/Next)_(complex) FOS Su(H) NIcs Complex_(Serrate/Next)_(complex) Serrate NIct Next Ntm Complex_(Mastermind/Su(H)/_CoA/NIcs)_(complex) MYC Notch Complex_(Notch/Delta)_(complex) HRAS KRAS
REACTOME_REACT_21308 MAP2K2 MAPK1 phospho-ERK-2_dimer_(complex) MEK2_ERK-2_(complex) phospho-ERK-2_MEK2_(complex)
PID_il2pathway IL2RA IL2RB SHC/GRB2/SOS-1_(complex) STAT5/STAT5_(complex) IL-2/IL-2R-alpha/IL-2R-beta/IL-2R-gamma/JAK1/JAK3/LCK/SYK_(complex) SOS1 IL2RG SYK HRAS STAT5 IL-2/IL-2R-alpha/IL-2R-beta/IL-2R-gamma/JAK1/JAK3_(complex) GRB2 IL2 JAK3 JAK1 LCK SHC1
PID_Folding_of_actin_by_CCT_TriC CCT8 CCT2 CCT3 CCT6A CCT/TriC(ADP)_(complex) CCT7 CCT4 CCT5 CCT/TriC(ATP)-associated_actin_(complex) CCT/TriC_(ADP)_associated_actin_(complex) ACTB CCT/TriC(ATP)_(complex) TCP1
PID_Uncoating_of_the_HIV_Virion Reverse_Transcriptase_heterodimer_(complex) uncoated_viral_complex_(complex) VIF Matrix EMBL_AF033819_EMBL_AF033819 Protease p6_protein Nucleocapsid p51_subunit_of_RT Rev HIV-1_RNA_homodimer_(complex) p66_subunit_of_RT Vpu_protein Vpr_protein Integrase PPIA Encapsidated_viral_core_(complex)
PID_antisensepathway NONO ADAR inosine_RNA dsRNA SFPQ edited_RNA MATR3 p54nrb/PSF/Matrin3/inosine_RNA_(complex)
PANTHER_P00060 Complex_(ubiquitin/E1)_(complex) E1 Protein_target E2
REACTOME_REACT_163812 SAE2_HUMAN_(complex) SUMO1_UBA2_SAE1_(complex) SUMO1 SUMO-activating_enzyme_subunit_2_(complex) SUMO2 SUMO_E1_enzyme_(complex) SAE1 UBA2 SUMO3_UBA2_SAE1_(complex) SUMO2_UBA2_SAE1_(complex) SUMO3
PID_Activation_of_DNA_fragmentation_factor caspase-3-cleaved_DFF45_(117_224)_DFF40_complex_(complex) DFF_cleaved_DNA_(complex) H1F0 CASP3 importin-alpha_importin-beta_complex_(complex) DFF45_DFF40_complex_(complex) Caspase_cleaved_DFF45_(117)_(complex) active_caspase-3_(complex) KPNB1 DFFA DFFB DFF_associated_with_the_importin-alpha_importin-beta_complex_(complex) DFF40_homodimer_(complex) importin-alpha_importin-beta_(complex) HMGB1/HMGB2-_bound_chromatin_(complex) KPNA1 DFF40_associated_with_chromatin_(complex) Histone_H1_bound_chromatin_DNA_(complex) HMGB1/HMGB2
PANTHER_P05911 EGR RhoA AngII/AT1-R_complex_(complex) beta-ARR1 beta-ARR2 GRK2 GRK3 PKC AngII b-ArrAT1aR_(complex) AT1-R Gqalpha CALB1 Gbeta Raf1 AngII/AT1-R_G_protein_complex_(complex) IP3R MEK ELK1 PLC CRAC Ggamma AT1R/G_protein_complex_(complex)
PID_mRNA_Decay_by_5__to_3__Exoribonuclease DCP2 Decapped_mRNA_LSM1-7_Complex_(complex) EDC4 LSM4 LSM5 LSM6 LSM1 LSM2 LSM3 Lsm1-7_Complex_(complex) EDC3 DDX6 DCP1B DCP1A DCP1-DCP2_Decapping_Complex_(complex) Deadenylated_mRNA_Lsm1-7_Complex_(complex) XRN1
PID_Interactions_of_Rev_with_host_cellular_proteins RCC1
PID_melanocytepathway RPS6KA1 SCF/SCF-R_(complex) MITF/p300_(complex) MAPK3 HRAS CREB1 KIT MAP2K2 MAP2K1 MAPK1 MITF KITLG EP300 RAF1
PID_NGF_signalling_via_TRKA_from_the_plasma_membrane NGF beta-NGF_homodimer_(complex) Activated_TrkA_receptor_complex_(complex) NTRK1
PID_pcsynthesispathway PCYT1A CEPT1 CHKA
REACTOME_REACT_1993 RPA_heterotrimer_(complex) RPA1 POLD2 RPA3 RPA2 POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 POLD4
PID_CYP2E1_reactions CYP2E1
REACTOME_REACT_120727 SMAD4 JUNB MEN1 SMAD2 Phospho-R-SMAD_(family) WWTR1_p-2S-SMAD2/3_SMAD4_(complex) p107_E2F4/5_DP1/2_(complex) p-SMAD2/3_SMAD4_RBL1_E2F4/5_DP1/2_(complex) Phospho-R-SMAD_CO-SMAD_complex_(complex) SERPINE1 UBIQ_HUMAN_(family) SMAD7_RNF111_(complex) p-T_2S-SMAD2/3_SMAD4_(complex) UBA52 RNF111 MYC CDKN2B RPS27A RBL1 SP1 Ub-SMAD7_(complex) SMAD7 SMAD3 p-2S-SMAD2/3_SMAD4_MEN1_(complex) p-T_2S-SMAD2/3_(family) p-S465/423_467/425-SMAD2/3_(family) E2F5 E2F4 E2F4/5_(family) WWTR1 p-2S-SMAD2/3_SMAD4_SP1_(complex) DP1/2_(family) UBB UBC TFDP2 TFDP1
BIOCYC_PWY-6620 HGPRTase_(complex) HPRT1 PNP_(complex)
PID_Transport_of_nucleotide_sugars SLC35A1 SLC35B2 UDP-glucuronate_transporter_homohexamer_(complex) SLC35B4 SLC35A2 SLC35A3 SLC35D2 SLC35D1 SLC35C1
PID_prionpathway HSP40 RPSA HSPA5 Laminin PRNP DNAJB6 Laminin/LAMR1_(complex) PrPsc GFAP BCL2
PID_Transport_of_Mature_Transcript_to_Cytoplasm NUP88 AAAS NUP133 NUP85 NUP62 SEH1L NUP98 NUP43 NUP188 NUP214 NUP210 RANBP2 POM121 NXF1 NUP107 Nup107_Complex_(complex) NUP160 NUP93 ALYREF TPR Nup62_Complex_(complex) NUPL1 NUPL2 EIF4E NUP50 NUP54 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 NUP153 NUP155 NUP205 RAE1
REACTOME_REACT_75842 UBE2Q1 UBE2Q2 UBE2J1 UBE2J2 Ubiquitin_activating_E1_enzymes_(family) UBE2D4 RPS27A UBE2D2 E2_Ubiquitin-conjugating_enzyme_(family) UBE2D1 UBE2L6 UBE2L3 UBE2V1 Ag-substrate_E3_E2_Ub_(complex) E3_Ub_substrate_(complex) Ub_substrate_(complex) CDC34 Ubiquitin_E2_conjugating_enzymes_(complex) ATG7 UBE2R2 UBE2G2 E3_K48-polyubiquitinated_substrate_(complex) UBE2E1 UBE2E3 UBE2D3 UBA6 UBA7 UBA5 UBA3 UBA1 UBE2M UBE2V2 UBE2E2 UBE2H UBE2K E1_bound_ubiquitin_(complex) UBE2O UBE2A UBE2C UBE2B UBE2F UBA52 UBE2Z UBB UBC UBE2S UBE2U ubiquitin_(family) UBE2W
PID_Amplification__of_signal_from_unattached__kinetochores_via_a_MAD2__inhibitory_signal MAD1L1 Mad1_kinetochore_complex_(complex) MAD2L1 Kinetochore_Mad1_MAD2__Complex_(complex) Kinetochore_Mad1_MAD2_Complex_(complex)
REACTOME_REACT_27258 TSG101 CHMP4A CHMP4B RPS27A ESCRT-II_(complex) CHMP2B CHMP2A CHMP3 Ubiquinated_and_PIP3_Endosmal_Membrane_Bound_Cargo_(complex) CHMP7 CHMP6 VPS25 VPS28 VPS37D ESCRT-I/Cargo_Complex_(complex) VPS37B VPS37A VPS37C CHMP4C CHMP2_(family) SNF8 ESCRT-I_(complex) VPS36 CHMP4_(family) UBA52 UBC ESCRT-II/Cargo_Complex_(complex) ESCRT-III_(complex) ESCRT-III/Cargo_Complex_(complex) ubiquitin_(family)
REACTOME_REACT_12623 phopshorylated_PLC-gamma1_bound_to_SLP-76_(complex) EVL ENAH PLCG1 p-SLP-76_ADAP_Ena/VASP_(complex) SLP-76_bound_to_Gads_LAT_(complex) FYB ITK_bound_to_SLP-76_Gads_LAT_(complex) PAK_(family) PLC-gamma1_bound_to_LAT_or_SLP-76_(complex) GRAP2 Phosphorylated_PLC-gamma1_bound_to_LAT_or_SLP-76_(complex) p-Y113_Y128_Y145-SLP-76_Gads__LAT_(complex) p-SLP-76_NCK1_(complex) Activated_PLC_gamma1_bound_to_PIP2_(complex) PLCG1_p-3Y-SLP-76_Gads_LAT_(complex) PLCG1_p-5Y-LAT_(complex) LCP2 VASP WAS Ena/VASP_proteins_(family) NCK1 p-SLP-76_NCK_PAK_(complex) ITK GADS_p-5Y-LAT_(complex) phosphorylated_PLC-gamma1_bound_to_LAT_(complex) p-SLP-76_ADAP_(complex) p-SLP-76_NCK1_WASP_(complex) LAT PAK1 PAK2
BIOCYC_PWY-6498-1 TYRP1 DCT TRPC1 TYR
PID_Immunoregulatory_interactions_between_a_Lymphoid_and_a_non_Lymphoid_cell ICAM_bound_to_integrin_CD11a-CD18_(complex) Ig_Antibody_Light_Chain KIR2DS2 AMICA1 B2M CD226 KIR2DS1_complexed_with_DAP12_(complex) TCR_interacting_with_antigen-bearing_MHC_Class_I_(complex) TYROBP Complex_of_CD19__CD81__CD225_and_CD21_(complex) Lymphoid-expressed_Fc-gamma_receptors HLA-C_group_2_interacting_with_KIR2DL1_(complex) CDH1 IFITM1 CRTAM_bound_to_NECL2_(complex) Antigen-bound_antibody_bound_to_lymphoid_Fc_gamma_receptors_(complex) VLA-4_bound_to_VCAM-1_(complex) IgG_Heavy_Chain MadCAM_inetracting_with_Integrin_alpha-4_beta-7_(complex) KIR2DS2_complexed_with_DAP12_(complex) CD8_(complex) T-cell_receptor_complex_(complex) CD3D CD3E CD3G KLRC1 CD40_complexed_with_CD40L_(complex) HLA-C HLA-B HLA-A CD3_epsilon_delta_(complex) HLA-G Complex_of_CD19__CD81__CD225_and_CD21_with_C3d-bound_Antigen_(complex) HCST CD200 L-selectin_interacting_with_known_ligands_(complex) HLA-C_group_1_interacting_with_KIR2DS2_(complex) LILR-interacting_MHC_Class_I_molecules_(complex) HLA-C_Cw4_(group_I)_(complex) KIR2DS1 PVRL2 MADCAM1 MHC_Class_I CD226_bound_to_Nectin_2_(complex) CXADR_bound_to_JAML_(complex) KIR3DL1 KIR3DL2 KLRG1 HLA-C_Cw3_(group_2)_(complex) CD3_epsilon_gamma_(complex) T-cell_receptor_complex_with_CD8_(complex) CD96 HLA_Bw4_interacting_with_KIR3DL1_(complex) HLA-A3_(complex) KIR2DL1 ITGAL Beta-2-microglobulin_class_I_MHC_heavy_chain_Complex_(complex) CD19 CD40LG Integrin_alpha4beta7_(complex) NKG2D_complexed_with_DAP10_(complex) Ligand_interacting_with_NKG2D_(complex) PVR HLA-Bw4_(complex) CD81 MHC_Class_I_interacting_with_CD160_(complex) HLA-E_(complex) HLA-C_group_2_interacting_with_KIR2DS1_(complex) C3 CD200R1 Antigen-bound_Ig_G_Antibody_(complex) ITGA4 VLA-4_(complex) VCAM1 T-cell_receptor_(complex) CD8A CD8B CXADR CRTAM CD200_bound_to_CD200R_(complex) HLA-G_interacting_with_KIR2DL4_(complex) MHC_Class_I_bearing_antigen_peptide_(complex) C3d_complexed_with_antigen_(complex) HLA-A3_interacting_with_KIR3DL2_(complex) MHC_Class_I_interacting_with_LILRs_(complex) KLRD1 CD247 E-cadherin_bound_to_KLRG1_(complex) TCR_chain_alpha CD226_bound_to_nectin-like_5_(complex) ITGB1 ITGB2 Integrin_CD11a-CD18_(LFA-1)_(complex) ITGB7 KIR2DL4 HLA-E_interacting_with_NKG2A-CD94_heterdimer_(complex) CD40 SELL Nectin-like_5_bound_to_CD96_(complex) KLRK1 CD160 HLA-C_group_1_interacting_with_KIR2DL2/3_(complex) TCR_chain_beta UniProt_O15181_cd21
PANTHER_P06210 IGKV4-1 DL KV403_HUMAN SARA/SMOX_(complex) phosphoSMOX_LACK_(complex) PUT/activinbeta_phosphoBABO_(complex) GBB_full_length_(complex) phosphoSMOX/_MED_(complex) LACK PUT_(complex) KV404_HUMAN PUT/activinbeta_phosphoBABO_SARA/phosphoSMOX_(complex) BCHE LV107_HUMAN CCK SCW_(complex) KV206_HUMAN PUT/activinbeta_BABO_(complex) myoglianin_(complex) IGF2 BMP_orthologous_ligand_(complex) MED MAD_(complex) BABO WIT_(complex) activinbeta_full_length PUT/activinbeta_(complex) __(complex) ALP23B_full_length_(complex) SARA HV107_HUMAN TRIF_(complex) SAX_(complex) PUT/activinbeta_phosphoBABO_SARA/SMOX_(complex) Full-length_BMP_orthologous_ligand SMOX_(complex) STAT_(complex) LCK proActivinbeta_(complex)
REACTOME_REACT_6361 UniProt_P04601_nef
PID_Beta_oxidation_of_decanoyl_CoA_to_octanoyl_CoA_CoA HADH Trifunctional_Protein_(complex) HADHB HADHA MCAD_acyl-CoA_dehydrogenase_homotetramer_(complex) short_chain_3-hydroxyacyl-CoA_dehydrogenase_homodimer_(complex) ECHS1 enoyl-CoA_hydratase_hexamer_(complex) ACADM
PID_EGFR_downregulation CIN85_Endophilin_(complex) EGF_Phospho-EGFR_(Y1045)_dimer_Ubiquitinated_Phospho-CBL_GRB2_(complex) EGF_Phospho-EGFR_(Y1045)_dimer_Phospho-CBL_GRB2_(complex) Eps15_HGS_STAM_(complex) EGF_Phospho-EGFR_(Y1045)_dimer_Phospho-CBL_(complex) EGFR EGF_Phospho-EGFR_(Y1045)_dimer_Phospho-CBL_CIN85_ubiquitinated_Endophilin_Epsin_Eps15R_Eps15_complex_(complex) CLTA CIN85_ubiquitinated_(complex) CLTC Phospho-CBL_GRB2_(complex) Cool/Pix_Ubiquitinated_CDC42-GTP_(complex) EGF Phospho-SPROUTY_ubiquitinated_(complex) SH3GL2 EPS15 AP2S1 Cool-1 EGF_Phospho-EGFR_(Y1045)_dimer_Phospho-CBL_CIN85_Endophilin_Epsin_Eps15R_Eps15_complex_(complex) Clathrin-coated_vesicle_(complex) CIN85_ubiquitinated_Endophilin_(complex) AP2M1 GRB2 CBL_GRB2_(complex) SH3KBP1 AP2B1 Phospho-Sprouty CBL_Cool/Pix_CDC42-GTP_(complex) EGF_Phospho-EGFR_(Y1045)_dimer_Ubiquitinated_Phospho-CBL_(complex) Cool/Pix_CDC42-GTP_(complex) EGF_Phospho-EGFR_(Y1045)_dimer_Phospho-CBL_GRB2_CIN85_Endophilin_Epsin_Eps15R_Eps15_complex_Clathrin_(complex) EPN1 HGS EGF_Phospho-EGFR_(Y1045)_dimer_Phospho-CBL_CIN85-Sprouty_Endophilin_Epsin_Eps15R_Eps15_complex_(complex) EGF_Phospho-EGFR_(Y1045)_dimer_CBL_GRB2_(complex) EPS15L1 Adaptor_protein_2_complex_(complex) Sprouty EGF_Phospho-EGFR_(Y1045)_dimer_Phospho-CBL_GRB2_CIN85_Endophilin_(complex) Adaptor_protein_complex_2_(AP-2)_large_adaptins CBL UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 CDC42-GTP_(complex) EGF_Phospho-EGFR_(Y1045)_dimer_CBL_Cool/Pix_CDC42-GTP_(complex) Clathrin_(complex) CBL_Sprouty_(complex) EGF_Phospho-EGFR_(Y1045)_dimer_CBL_(complex) STAM EGF_Phospho-EGFR_(Y1045)_dimer_CBL_Phospho-Sprouty_ubiquitinated_(complex) CDC42
PID_Transport_of_the_SLBP_independent_Mature_mRNA NUP88 AAAS NCBP1 NCBP2 Mature_Intronless_Transcript_Derived_Histone_mRNA_TAP_Aly/Ref_Complex_(complex) NUP85 NUP62 NUP133 NUP98 NUP43 NUP188 Cap_Binding_Complex_(CBC)_(complex) NUP214 NUP210 RANBP2 POM121 NXF1 NUP107 Nup107_Complex_(complex) NUP160 NUP93 ALYREF TPR Nup62_Complex_(complex) NUPL1 NUPL2 SEH1L NUP50 NUP54 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 NUP153 NUP155 NUP205 RAE1
PANTHER_P00020 Complex_(FasL/FasL)_(complex) Caspase10 Pro-Caspase9 PARP Pro-Caspase6 Pro-Caspase7 Complex_(Fas/Fas)_(complex) Apaf1 CAD DAXX Complex_(FasL/FasL/_Fas/Fas)_(complex) Bid Fas_(complex) c-Jun FADD Pro-Caspase3 Caspase6 Caspase7 Complex_(Caspase9/Apaf1)_(complex) ASK1 Caspase3 FAF1 Caspase8 Caspase9 Complex_(FasL/Fas/_FasL/Fas/_FADD/DAXX/_FAF1)_(complex) Pro-Caspase10 Cubitus_interruptus ICAD MKK4 _ Gelsolin Pro-Caspase8 Nuclear_Lamin JNK FasL_(complex)
REACTOME_REACT_169439 3_cytosolic_halocarboxylases_(complex) PCCA ACACA mitochondrial_holocarboxylases_(complex) ACACB PCCB methylcrotonyl-CoA_carboxylase_complex_(complex) 3-methylcrotonyl-CoA_carboxylase_complex_(complex) 4x(Btn-PC_Mn2+)_(complex) 4x(PC_Mn2+)_(complex) PC biotinylated_propionyl-CoA_carboxylase_dodecamer_(complex) propionyl-CoA_carboxylase_protomer_(complex) ACACA_2Mn2+_(complex) Btn-ACACA_2Mn2+_(complex) propionyl-CoA_carboxylase_dodecamer_(complex) ACACB_2Mn2+_(complex) MCCC2 MCCC1 Btn-ACACB_2Mn2+_(complex)
PID_Processing_of_Capped_Intronless_Pre_mRNA SNRPD3 U7_snRNP-specific_Sm_core_complex_(complex) U7_snRNP_ZFP100_Complex_(complex) LSM10 LSM11 SNRPB ZNF473 SNRPF SNRPG SNRPE
PID_Formation_of_ATP_by_chemiosmotic_coupling ATP5C1 ATPase_CF(1)_(complex) ATPase_CF(0)_(complex) ATPase-ADP_and_Pi_complex_(complex) ATP5J2 ATPase-ATP_complex_(complex) ATP5A1 ATPase_complex_(complex) MT-ATP8 ATP5J ATP5I ATP5H ATP5O ATP5L ATP5B MT-ATP6 ATP5D ATP5G1 ATP5E ATP5F1
PID_Ubiquitin_Mediated_Degradation_of_Phosphorylated_Cdc25A PSMD9 PSMD8 PSMB10 PSMD5 PSMD4 PSMD7 ATM PSMD1 PSMD3 PSMD2 PSMF1 PSMA2 PSMA3 PSMA1 PSMA6 PSMA4 PSMA5 PSMC1 PSMC2 PSMC3 CHEK2 PSMC5 PSMC6 CHEK1 PSMD6 Ubiquitinated_Phospho-Cdc25A_(complex) CDC25A PSME2 PSME3 PSME1 PSMD14 PSMC4 PSMD11 PSMD10 PSMD13 PSMD12 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 PSMB9 PSMB8 PSMB7 PSMB6 PSMB5 PSMB4 PSMB3 PSMB2 PSMB1
PID_PP2A_mediated_dephosphorylation_of_key_metabolic_factors MLXIPL PFKFB1 PP2A-ABdeltaC_complex_(complex) PF2K-Pase1_homodimer_(complex)
PID_Assembly_of_Viral_Components_at_the_Budding_Site Glycosylated_NA_Tetramer_(complex) Gycosylated_NA_Tetramer_(complex) UniProt_P06821_M NP_Lipid_Raft_(complex) CALR palmitylated_M2_Tetramer_(complex) Glycosylated__palmitylated_and_folded_HA_trimer_Lipid_Raft_Complex_(complex) Glycosylated__palmitylated_and_folded_HA_trimer_(complex) M2_Tetramer_(complex) Glycosylated_and_folded_HA_trimer_(complex) Gycosylated_NA_Tetramer_Lipid_Raft_(complex) UniProt_P03466_NP UniProt_P03485_M UniProt_P03452_HA UniProt_P03468_NA CANX
BIOCYC_PWY-2301 myo-inositol_monophosphatase_A2_(complex) ISYNA1 IMPA1 IMPA2 IMPAD1 inositol(myo)-1(or_4)-monophosphatase_1_(complex)
PID_Classical_antibody_mediated_complement_activation Ig_Antibody_Light_Chain C1_complement_factor_(with_activated_C1R)_(complex) Ig_G_Antibody_(complex) Antigen__antibody__C1_complex_(complex) C1S_activated_C1R_tetramer_(complex) C1Q_(complex) Antigen-antibody_complex_(complex) C1_complement_factor_(with_activated_C1R_and_C1S)_(complex) Antigen__antibody__C1_(activated_C1R_and_C1S)_complex_(complex) C1_complement_factor_(complex) C1S_C1R_tetramer_(complex) C1Q_subunit_(C1QA_C1QB_C1QC_heterotrimer)_(complex) Antigen__antibody__C1_(activated_C1R)_complex_(complex) IgG_Heavy_Chain Activated_C1S_(complex) C1QC C1QB C1QA Activated_C1S_activated_C1R_tetramer_(complex) C1S C1R Activated_C1R_(complex)
PID_mef2dpathway CAPNS1 TCR-CD3/MHC_II/CD4_(complex) CD4 PLCG1 CD247 HLA-DRA CABIN1 FYN PKC CaM/Ca_++_(complex) MHC_class_II_beta CAPN2 NFATc TCR-beta TCR-alpha Calpain2_(complex) NR4A1 TCR-CD3/MHC_II/CD4/LCK/ZAP70_(complex) ZAP70 TCR-CD3/MHC_II/CD4/LCK_(complex) CD3E PTPRC CaM LAT PPP3CA PPP3CB PPP3CC CD3D LCK Calcineurin_(complex) CD3G
REACTOME_REACT_163710 SNX3 WLS_WNT_(complex) unglycosylated_WNTs_(family) WLS N-glycosylated_WNTs_(family) palmitoleyl-N-glycosylated_WNTs_(family) WLS_retromer_(complex) WNT10B VPS29 WNT8A WNT8B retromer_subcomplex_(complex) WNT2B WNT5B VPS26A WNT3A palmitoleoyl-N-glycosylated_WNTs_(family) VPS35 WNT3 WNT2 WNT1 WNT6 WNT4 WNT9B WNT9A WNT10A WNT16 WNT5A WNTs_(family) WNT7A WNT11 WNT7B
PID_Notch_HLH_transcription_pathway CSL SNW1 KAT2B CREBBP CSL_NICD_coactivator_complex_(complex) MAM NICD
REACTOME_REACT_20510 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 Phospho(S363_S380_T573)-ribosomal_S6_kinase_(family) Phospho(S363_S380_T573)-_ribosomal_S6_kinase_(family) Phospho(S221_S363_S380_T573)-_ribosomal_S6_kinase_(family) Ribosomal_S6_kinase_(family)
BIOCYC_PWY66-14 YWHAB H/K/N-Ras activated_Raf1_complex_(complex) phospho-ERK_dimer_(complex)
PID_Sphingolipid_metabolism ceramide_CERT_(complex) LASS_proteins SGMS1 PPAP2A CERT_PPM1L_VAPA/B_trimer_(complex) SGMS2 SPHK VAPA/B ACER2 ACER3 SGPL1 ACER1 PPM1L_VAPA/B_dimer_(complex) PPM1L PPAP2 COL4A3BP multiphospho-CERT_PPM1L_VAPA/B_trimer_(complex) KDSR CSNK1G2 DEGS1 DEGS2 PRKD1 ceramide_CERT_PPM1L_VAPA/B_trimer_(complex) OSBP SGPP
PID_The_fatty_acid_cycling_model FA_anion_UCP_dimer__head-out__complex_(complex) UCP_dimer_(complex) FA_anion_UCP_dimer__head-in__complex_(complex)
PID_plcpathway PLCB1 PIK3CA PLCG1 PIK3R1 PI3K_(complex) PDPK1
PID_Cytosolic_sulfonation_of_small_molecules BPNT1 SULT2B1_b_isoform_homodimer_(complex) SULT1E1_homodimer_(complex) SULT1A4 TL_phenol_transferase_1A3_homodimer_(complex) SULT1A1 Phenol_sulfotransferase_(1A1)_homodimer_(complex) SULT2B1 SULT1E1 SULT2A1_homodimer_(complex) SULT2A1
PID_Dopamine_clearance_from_the_synaptic_cleft SLC6A3 MAOA MAOA-FAD_complex_(complex) COMT
PID_Acetylcholine_Neurotransmitter_Release_Cycle STX1A SNAP25 VAMP2 CHAT SYT1 Docked_acetylcholine_loaded_Synaptic_Vesicle_(complex) Acetylcholine_Loaded_Synaptic_Vesicle_(complex) STXBP1 SLC18A3 CPLX1 RAB3A SLC5A7 Empty_Acetylcholine_Synaptic_Vesicle_(complex) RIMS1
REACTOME_REACT_607 CASP7 active_caspase-3_(complex) CASP3 SMAC_XIAP_Caspase-3_(complex) SMAC_XIAP_Caspase-9_(complex) active_caspase-7_(complex) XIAP_Caspase-9_(complex) CASP9 XIAP_Caspase-3_(complex) XIAP DIABLO Cleaved_Caspase-9_(complex) SMAC_XIAP_Caspase-7_(complex) XIAP_Caspase-7_(complex)
REACTOME_REACT_18312 NCAM-1_ATP_(complex) NCAM1_T-_and_L-type_VDCC_(complex) NCAM-1_Collagen_complex_(complex) GFRalpha_(family) NCAM1_GFRalpha-1_(complex) CNTN2 NCAM1 NCAN NCAM1-Contactin-2_(complex) Polysialylated_NCAM_(complex) PRNP NRTN ARTN NCAM-1_Neurocan_(complex) PSPN GDNF_family_ligands_(GFLs)_(family) NCAM1_GFRalpha-1_GDNF_(complex) NCAM-1_Agrin_(complex) NCAM1_NCAM1_trans-homotetramer_(complex) AGRN GFRA4 GFRA1 GDNF NCAM-1_Major_prion_protein_(complex) GFRA2 NCAM1_cis-homodimer_(complex)
REACTOME_REACT_1221 ubiquitin_(family) RPS27A UBA52 UBB UBC ubiquitinated_Cdc6_(complex) CDC6
PID_Fatty_acids CYP2J2 CYP4F12 CYP4A11 CYP4B1
PID_Lectin_pathway_of_complement_activation Activated_MASP-2_dimer_(complex) MBL-II_MASP-2_dimer_MASP-1_dimer_complex_(complex) MBL-II_tetramer_(complex) Activated_MBL_bound_to_mannose-based_carbohydrates_on_bacterial_surfaces_(complex) MASP-2_dimer_(complex) MBL_subunit_(complex) MASP1 MASP2 MBL_bound_to_mannose-based_carbohydrates_on_bacterial_surfaces_(complex) MASP-1_dimer_(complex) Activated_MASP-1_dimer_(complex) MBL-II_Activated_MASP-1_dimer_Activated_MASP-2_dimer_complex_(complex) MBL2
PID_gata3pathway MAPK14 cAMP_activators ADCY1 PRKAR1A MAP2K3 PKA_(complex) PRKACG PRKAR2B MAP2K6 PRKAR1B PRKACB G-alpha-S GATA3 PRKAR2A G-alpha-S/AC_(complex)
REACTOME_REACT_6804 GCK glucokinase_glucokinase_regulatory_protein_complex_(complex) GCKR
BIOCYC_PWY-5269 CRLS1 PGS1
PID_bard1pathway2 BRCA1 FANCD2 BARD1 FANCD2/ubiquitin_(complex) FANCG FANCF FANCE FA_complex/FANCD2/Ubiquitin_(complex) FANCC FANCA FA_complex_(complex) ubiquitin BRCA1/BARD1_(complex)
PID_eNOS_activation_and_regulation palmitoylated__myristoylated_eNOS_dimer_(complex) eNOS_Caveolin-1_(complex) NOS3 CAV1
PID_Digestion_of_dietary_carbohydrate TREH LCT maltase-glucoamylase_dimer_(complex) AMY2A MGAM SI lactase-phlorizin_hydrolase_dimer_(complex) sucrase-isomaltase_dimer_(complex) sucrase-isomaltase_(complex)
PID_nfatpathway RAS_activating_ligand/RAS_activating_receptor_(complex) HDAC5 HDAC9 PI3K_(complex) HRAS CaM/Ca_++_(complex) AKT1 HAND1 HAND2 SERCA NFATc(+)/GATA4_(complex) NFATc(+)/MEF2C/GATA4_(complex) NKX2-5 CaMKI/CaM/Ca_++_(complex) PIK3CA SHC/GRB2/SOS-1_(complex) RPS6KB1 CAMK4 MITR/MEF2_(complex) CaMKI CaMKK PIK3R1 NFATc MAPK8 MCIP ELSPBP1 SHC1 NFATc(+)/CBP_(complex) MITR/14-3-3_(complex) CaMKI/CaM/Ca_++_(nuc)_(complex) PPP3CA RAS_activating_receptor GATA4 PPP3CB SOS1 CamKIV/CaM/Ca_++_(complex) GSK3B MEF2C NFATc(+)/MEF2C/HAND1/HAND2/NKX_2.5/E12_(complex) GRB2 CREBBP CaM PDPK1 CaMKK/CaM/Ca_++_(complex) PPP3CC RAS_activating_ligand Calcineurin_(complex) YWHAH
PID_FGFR3_ligand_binding_and_activation GRB2 SDC2 Activated_FGFR_complexed_with_phosphorylated_FRS2__GRB2_and_CBL_(complex) CBL Phospho-FRS2
PID_Class_II_GLUTs GLUT7/11 SLC2A5 SLC2A9
BIOCYC_PWY-5329 MPST
REACTOME_REACT_11038 STAR cholesterol_STAR_(complex) StAR-related_cholesterol-binding_proteins_(family) cholesterol_StAR-related_protein_(complex) STARD6 STARD4 STARD5
REACTOME_REACT_19195 Necl-1_Nectin-3_trans_heterodimer_(complex) Necl-1_Nectin-1_trans_heterodimer_(complex) Nectin-4_cis_homodimer_(complex) PVRL3_dimer_(complex) Nectin-1_PVRL3_trans_heterodimer_(complex) Nectin-3_Necl-2_trans_heterodimer_(complex) Nectin-2_cis_homodimer_(complex) PVRL1 PVRL4 PVRL3 PVR Nectin-2_PVRL3_transheterodimer_(complex) PVRL2 Necl-1_Necl-2_trans_heterodimer_(complex) PRV_PVRL3_trans_heterodimer_(complex) Nectin-1_Nectin-4_trans_heterodimer_(complex) Nectin-1_cis_homodimer_(complex) CADM3 CADM1
REACTOME_REACT_111225 MAP2K2 MAPK1 phospho-ERK-2_dimer_(complex) MEK2_ERK-2_(complex) phospho-ERK-2_MEK2_(complex)
PID_Activation_of_NOXA_and_translocation_to_mitochondria TFDP1 PMAIP1 DP-1_E2F1_complex_(complex) E2F1
PID_Metabolism_of_steroid_hormones_and_vitamin_D CYP17A1 CYP11B1 CYP21A2
PID_Pentose_phosphate_pathway__hexose_monophosphate_shunt_ PGD TALDO1 PGLS RPE_dimer_(complex) transketolase_dimer_(complex) PGD_dimer_(complex) TKT RPE RPIA
REACTOME_REACT_150128 FDXR FDXR_FADH2_(complex) FDXR_FAD_(complex)
REACTOME_REACT_20617 ITGB1 PARVA_Paxillin_(complex) ILK ILK_Integrin_beta-1_(complex) PXN PARVA
PANTHER_P02782 Triacylglycerol_lipase Protein_Kinase_A Insulin
REACTOME_REACT_23810 unfolded_protein_(Glc)1_(GlcNAc)2_(Man)9_(Asn)1_chaperone_ERp57_(complex) CALR calnexin_calreticulin_(complex) PDIA3 unfolded_protein_(Glc)1_(GlcNAc)2_(Man)9_(Asn)1_chaperone_(complex) (un)folded_protein_(GlcNAc)2_(Man)9_(complex) CANX
REACTOME_REACT_121380 Hemoglobin_beta_ferroheme_b_oxygen_(complex) Hemoglobin_alpha_ferroheme_b_oxygen_(complex) HBA2 Oxygenated_Hemoglobin_alpha_Hemoglobin_beta_Tetramer_(complex) HBB
PID_mprpathway progesterone/mPR/G-beta/G-gamma/G-alpha-I_(complex) HRAS PRKAR2A PKA_(complex) PRKAR2B PIN1 CDC2/cyclin_B_(complex) GNAI1 CAP1 MAPK3 MAPK1 PGR MYT1 SRC CDC25C GNB1 progesterone/iPR_(complex) PAQR5 MYT1/pin1_(complex) PRKAR1A PRKAR1B progesterone/iPR/SRC_(complex) G-alpha-S CCNB1 ADCY1 CDK1 PRKACG GNGT1 PRKACB
PID_Nef_Mediated_CD8_Down_regulation myristoylated_Nef_Protein_(numerous_variants) AP2S1 CD8_Nef_Complex_(complex) ATP6V1H Adaptor_protein_complex_2_(AP-2)_large_adaptins AP2M1 AP-2_Complex_(complex) CD8_Nef_AP-2_Complex_v-ATPase_Complex_(complex) CD8B AP2B1 Internalized_CD8_Nef_Clathrin-Coated_Pit_Adapter_Protein_v-ATPase_(complex)
PID_hespathway DKK2/LRP6/KRM2_(complex) Gamma_Secretase_(complex) NAKED WIF1 ADAM17 KREMEN2 GSK3B NICD/CSL_(complex) FZD1 NOTCH AXIN1 LRP6/FRIZZLED_(complex) PSEN1 NEXT DVL1 CK-1 WNT/LRP6/FRIZZLED_(complex) LFNG DLL1 CSNK2A1 DELTA/NOTCH/NOTCH(cleaved)_(complex) LRP6 WNT1 DKK2 DKK1 DKK1/LRP6/KRM2_(complex) HES1 RBPJ NICD HES7
PID_s1p_s1p4_pathway Erk1-2-active S1P/S1P5/Gi_(complex) PLCG1 S1PR5 S1P/S1P5/G12_(complex) S1P/S1P4/G12/G13_(complex) CDC42-GTP_(complex) ERK1-2 GNA12 GNA13 Gi_family S1P/S1P4/Gi_(complex) RHOA S1PR4 CDC42
REACTOME_REACT_150149 PTGS2 PTGS1 PGHS2_dimer_(complex) Ac-PTGS1_dimer_(complex) PTGS2_celecoxib_(complex) Ac-PTGS2_dimer_(complex)
PID_Toll_Like_Receptor_5__TLR5__Cascade TLR5_homodimer_bound_to_bacterial_flagellin_(complex) fliC TLR5
PID_Vpr_mediated_induction_of_apoptosis_by_mitochondrial_outer_membrane_permeabilization Vpr_protein ANT1_Vpr_complex_(complex) ADP/ATP_translocase_monomer_(generic)
PID_Serotonin_Neurotransmitter_Release_Cycle STX1A SNAP25 VAMP2 SYT1 Docked_serotonin_loaded_synaptic_vesicle_(complex) Serotonin_loaded_synaptic_vesicle_(complex) STXBP1 CPLX1 RAB3A SLC18A2 RIMS1
REACTOME_REACT_15502 SREBP1A_2_(family) HMGCS1 NF-Y_(complex) NFYB NRF1_PGC-1beta_ALAS1_gene_(complex) SREBF1A/2_NF-Y_HMGCR_gene_(complex) SREBF1A/1C/2_Dimer_(complex) SREBF2 PPARGC1B NFYC ALAS1 NFYA SREBF1 SREBF1A/1C/2_NF-Y_SP1_FDFT1_gene_(complex) HMGCR SP1 SREBF1A/1C/2_NF-Y_HMGCS1_gene_(complex) SREBP1A_1C_2_cleaved_by_S2P_(family) FDFT1 SREBF1A/2_Dimer_(complex) NRF1
PID_Vif_mediated_degradation_of_APOBEC3G PSME3 PSMD9 PSMD8 PSMB10 PSMD5 PSMD4 PSMD7 PSMD6 PSMD1 PSMD3 PSMD2 PSMF1 Vif_APOBEC3G_complex_(complex) PSMA2 PSMA3 PSMA1 PSMA6 PSMA7 PSMA4 TCEB2 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSME2 APOBEC3G_Vif_Cul5_SCF_complex_(complex) TCEB1 PSME1 CUL5 multi-ubiquitinated_APOBEC3G_Vif_Cul5_SCF_complex_(complex) RBX1 VIF PSMD14 APOBEC3G PSMD11 PSMD10 PSMD13 PSMD12 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 Cul5-SCF_complex_(complex) PSMB9 PSMB8 PSMB7 PSMB6 PSMB5 PSMB4 PSMB3 PSMB2 PSMB1
REACTOME_REACT_1614 Ubiquitinated_Phospho-Cdc25A_(complex) ubiquitin_(family) RPS27A UBC CDC25A CHEK1
BIOCYC_PWY-6405 PGAM-M_(complex) BPGM bisphosphoglycerate_2-phosphatase_(complex) PGAM2 PGAM1 PGAM-B_(complex) MINPP1
PID_Phosphorylation_of_Emi1 CCNB1 Cyclin_B1_phospho-Cdc2(Thr_161)_(complex) Emi1_Cdc20/Cdh1_complex_(complex) Cdc20/Cdh1 PLK1 phospho-Emi1(Ser_145__Ser_149)_Cdc20/Cdh1_complexes_(complex) CDK1 FBXO5 Phospho-Emi1(Ser_182)_Cdc20/Cdh1_complexes_(complex)
BIOCYC_MALATE-ASPARTATE-SHUTTLE-PWY GOT2 GOT1 GOT1L1 MDH2 TRANSAMINASE_A_GLUTAMATE_OXALOACETATE_TRANSAMINASE
REACTOME_REACT_11070 3_cytosolic_halocarboxylases_(complex) PCCA ACACA mitochondrial_holocarboxylases_(complex) ACACB PCCB methylcrotonyl-CoA_carboxylase_complex_(complex) 4x(Btn-PC_Mn2+)_(complex) 4x(PC_Mn2+)_(complex) PC biotinylated_propionyl-CoA_carboxylase_dodecamer_(complex) propionyl-CoA_carboxylase_protomer_(complex) ACACA_2Mn2+_(complex) Btn-ACACA_2Mn2+_(complex) ACACB_2Mn2+_(complex) MCCC2 MCCC1 Btn-ACACB_2Mn2+_(complex)
PID_Cholesterol_biosynthesis MSMO1 TM7SF2 NSDHL DHCR7 SC5D GGPS1 SQLE Isopentenyl-diphosphate_delta-isomerase_(Mg2+_cofactor)_(complex) LBR LSS CYP51A1 Mevalonate_kinase_homodimer_(complex) FDFT1 HSD17B7 HMGCS1 FDFT_(Mg2+_cofactor)_(complex) Isopentenyl-diphosphate_delta-isomerase Squalene_monooxygenase_(FAD_cofactor)_(complex) Diphosphomevalonate_decarboxylase_homodimer_(complex) MVD MVK DHCR24 GGPP_synthase_homooctamer_(complex) PMVK EBP Hydroxymethyl_glutaryl_CoA_reductase Hydroxymethyl_glutaryl_CoA_reductase_homodimer_(complex)
PID_Activation_of_BAD_and_translocation_to_mitochondria_ PPP3R1 BID tBID_BCL-2_(complex) AKT1 BAD YWHAB 143B_phospo-BAD_complex_(complex) BAD_BCL-2_(complex) PPP3CC Calcineurin_B_complex_(complex) BCL2
PID_CREB_phophorylation_through_the_activation_of_Ras HRAS CREB1 Ras_GTP_(complex) MAPK1 Phospho(S221_S363_S380_T573)-_ribosomal_S6_kinase RAF1
PID_Inactivation_of_Cdc42_and_Rac CDC42-GDP_(complex) Glypican-1_HSPG_(complex) RAC1 ROBO1 RAC1-GDP_(complex) Slit2_Glypican-1_(complex) SrGAP GPC1 SLIT2 RAC1-GTP_(complex) ARHGAP39 Robo1_Slit2_KIAA1688_(complex) Robo1_Slit2_SrGAP_(complex) Robo1_Slit2_Glypican-1_(complex) CDC42
PID_npcpathway NUTF2 Cargo Cargo/Importin-alpha/Ran/GDP/Importin-beta/NTF2_(complex) RCC1 NUP62 Cargo/Importin-alpha/Ran/GTP/Importin-beta_(complex) RANBP1 RAN NUP210 KPNB1 RANGAP1 NUP153 NUP214 Cargo/Importin-alpha/Ran/GTP/Importin-beta/NTF2_(complex) Ran/GTP/Importin-beta_(complex) KPNA2 Ran-GTP_(complex) NPC_(complex) Cargo/Importin-alpha_(complex) RanGAP/RanBP1/RanBP2_(complex) RANBP2
REACTOME_REACT_25078 IRF8 MT2A FCGR1A HLA-C HLA-B HLA-A HLA-G HLA-F HLA-E OASL B2M Interferon-induced_guanylate-binding_proteins_(family) PTAFR FCGR1B Class_I_MHC_heavy_chain_(MHC_HC)_(family) IFNGR_complex_with_p-JAK_(complex) NCAM1 p-STAT1_dimer_bound_to_p-IFNGR1_(complex) HLA-DRA IFNGR2_p-JAK2_(complex) IFNG_IFNGR1_p-JAK1_IFNGR2_p-JAK2_(complex) STAT1 CIITA IFNG_homodimer_(complex) Fc-gamma_receptor_alpha_(family) OAS1 IFNG OAS3 OAS2 HLA-DQB1 ICAM1 GBP2 PML IFNG_IFNGR1_JAK1_IFNGR2_JAK2_(complex) IFNGR1_p-JAK1_(complex) IRF_1-9_(family) VCAM1 IFNA-activated-factor_(AAF)_(complex) IFNGR2 HLA-DPB1 HLA-DRB1 GAF_bound_to_GAS_promoter_element_(complex) IFNGR_complex_with_p-JAK2_(complex) GBP3 CD44 GBP1 HLA-DQB2 GBP7 GBP6 GBP5 GBP4 IFN-gamma_upregulated_CAMs_(family) STAT1_bound_to_p-IFNGR1_(complex) IFNGR1_JAK1_INFG2_JAK2_(complex) HLA-DRB4 IFNGR2_JAK2_(complex) MHC_class_II_alpha/beta_dimer_(complex) HLA-DRB5 IFI30 JAK1 IRF6 IRF3 IRF2 IRF1 JAK2 IRF7 IRF5 HLA-DRB3 IFNG_IFNGR1_JAK1_IFNGR2_p-JAK2_(complex) IRF9 HLA_II_beta_chain_(family) OAS_proteins_(family) IRF4 IFNG-activated_factor_(GAF)_(complex) IFNG_p-IFNGR1_p-JAK1_IFNGR2_p-JAK2_(complex) p-STAT1(Y701)_bound_to_p-IFNGR1_(complex) p-IFNGR1_pJAK1_IFNGR2_p-JAK2_(complex) IFNGR1_JAK1_(complex) HLA_II_alpha_chain_(family) HLA-DPA1 p-IFNGR1_p-JAK1_(complex) SP100 HLA-DQA1 HLA-DQA2 IFNGR1
BIOCYC_LIPAS-PWY HS11909-MONOMER LIPC PNLIPRP2 LIPE LIPG LIPF MGLL CEL HS11905-MONOMER PNLIPRP3 ABHD12 PNPLA3 PNLIP PNPLA4 ABHD6
PID_Viral_dsRNA_TLR3_TRIF_Complex_Activates_RIP1 NF-kB_complex_(complex) RIPK1 Viral_dsRNA_TLR3_TRIF_complex_(complex) Nuclear_factor_NF-kappa-B Viral_dsRNA_bound_to_TLR3_(complex) Inhibitor_of_KappaB_kinase_(IKK)_Complex_(complex) CHUK Viral_dsRNA_TLR3_TRIF_RIP1_complex_(complex) IKBKB TLR3 RIPK3 IKBKG Activated_IKK_Complex_(complex) RELA TICAM1
REACTOME_REACT_6821 BTRC SCF-beta-TrCP_phospho-Emi1_complexes_(complex) SKP1 ubiquitin_(family) RPS27A SCF-associated_multiubiquitinated_Emi1complexes_(complex) FZR1 UBA52 SCF-beta-TrCP1_complex_(complex) UBB UBC Cdc20/Cdh1_(family) CDC20 CUL1 phospho-Emi1_Cdc20/Cdh1_complexes_(complex)
PID_Amine_derived_hormones DDC Dopa_decarboxylase_homodimer_(pyridoxal_phosphate_cofactor)_(complex)
PID_cb1rpathway CNR1 CNR2 FAAH PLD1 PLD2 PLD3 anandamide/CB-1R_(complex) BAAT anandamide/CB-2R_(complex)
REACTOME_REACT_115893 monoubiquitinated_N-myristoyl_GAG_(P04591)_protein_(complex) ubiquitin_(family) RPS27A UniProt_P04591_gag UBA52 UBB UBC
REACTOME_REACT_121061 SMAD4 JUNB MEN1 SMAD2 Phospho-R-SMAD_(family) WWTR1_p-2S-SMAD2/3_SMAD4_(complex) p107_E2F4/5_DP1/2_(complex) p-SMAD2/3_SMAD4_RBL1_E2F4/5_DP1/2_(complex) Phospho-R-SMAD_CO-SMAD_complex_(complex) SERPINE1 UBIQ_HUMAN_(family) SMAD7_RNF111_(complex) p-T_2S-SMAD2/3_SMAD4_(complex) UBA52 RNF111 MYC CDKN2B RPS27A RBL1 SP1 Ub-SMAD7_(complex) SMAD7 SMAD3 p-2S-SMAD2/3_SMAD4_MEN1_(complex) p-T_2S-SMAD2/3_(family) p-S465/423_467/425-SMAD2/3_(family) E2F5 E2F4 E2F4/5_(family) WWTR1 p-2S-SMAD2/3_SMAD4_SP1_(complex) DP1/2_(family) UBB UBC TFDP2 TFDP1
PID_Entry_of_Influenza_Virion_into_Host_Cell_via_Endocytosis CLTC EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 EMBL_AF389119_H1N1_Genomic_RNA_Segment_5 CLTA EMBL_AF389120_H1N1_Genomic_RNA_Segment_6 Ribonucleoprotein_(RNP)_Complex_(complex) Influenza_A_Viral_Envelope_(complex) palmitylated_M2_Tetramer_(complex) UniProt_P03485_M EMBL_AF389117_H1N1_Genomic_RNA_Segment_3 UniProt_P03466_NP UniProt_P03431_PB1 UniProt_P03508_NS UniProt_P03428_PB2 EMBL_AF389122_H1N1_Genomic_RNA_Segment_8 Influenza_A_Viral_Particle_(complex) UniProt_P03452_HA UniProt_P03433_PA EMBL_AF389115_H1N1_Genomic_RNA_Segment_1 EMBL_AF389118_H1N1_Genomic_RNA_Segment_4 UniProt_P06821_M Gycosylated_NA_Tetramer_(complex) EMBL_AF389116_H1N1_Genomic_RNA_Segment_2 UniProt_P03468_NA Clathrin_(complex) Cleaved_Trimeric_palmitylated_HA_(complex)
PID_tcrcalciumpathway NFAT1-c-4-active RCAN1 JUNB Calcineurin_A_alpha-beta_B1_(complex) Calcineurin_A_alpha-beta_B1/FKBP12/FK506_(complex) NFAT1-c-4 CABIN1 CALM1 JUN FOSL1 JUNB/Fra1/NFAT1-c-4_(complex) Calcineurin_A_alpha-beta_B1/DSCR1_(complex) Calcineurin_A_alpha-beta_B1/DSCR1L1_(complex) RCAN2 FOS JUN/FOS/NFAT1-c-4_(complex) AKAP5 Serine/Threonine_Kinases CaM/Ca2+_(complex) PRKACA Calcineurin_A_alpha-beta_B1/CABIN1_(complex) FKBP1A Calcineurin_A_alpha-beta_B1/AKAP79/PKA_(complex) CaM/Ca2+/Calcineurin_A_alpha-beta_B1_(complex)
REACTOME_REACT_1095 POLA2 POLA1 Orc2_associated_with_MCM8_(complex) active_pre-replicative_complex_(complex) POLE RPA_Cdc45_CDK_DDK_Mcm10_pre-replicative_complex_(complex) CDC6 CDC7 CDT1_CDC6_ORC_origin_complex_(complex) phosphorylated_Mcm2-7_complex_(complex) CDT1 DNA_Replication_Factor_A_(complex) PRIM1 Mcm10_pre-replicative_complex_(complex) DDK_(complex) DNA_polymerase_alpha_primase_DNA_polymerase_alpha_origin_complex_(complex) ORC4 CDC6_ORC_origin_complex_(complex) DNA_polymerase_epsilon_(complex) MCM10 DNA_polymerase_epsilon_origin_complex_(complex) ORC6 DNA_polymerase_alpha_primase_(complex) ORC5 ORC2 ORC3 ORC1 MCM7 CDC45 MCM5 MCM4 MCM3 MCM2 Mcm2-7_complex_(complex) MCM8 pre-replicative_complex_(complex) MCM6 RPA4 Cdc45_CDK_DDK_Mcm10_pre-replicative_complex_(complex) RPA1 RPA3 RPA2 CDK2 Mcm10_active_pre-replicative_complex_(complex) DBF4 POLE2 CDK_DDK_Mcm10_pre-replicative_complex_(complex) PRIM2 ORC_origin_(complex) CDK_(complex)
REACTOME_REACT_21328 MAP2K2 MAPK1 phospho-ERK-2_dimer_(complex) MEK2_ERK-2_(complex) phospho-ERK-2_MEK2_(complex)
REACTOME_REACT_21374 Activated_FGFR_SHC1_(complex) p21_RAS_(family) SHC1_p46_and_p52_(family) SHC1 SOS1 NRAS HRAS Activated_FGFR_p-SHC1_(complex) Activated_FGFR_p-SHC1_GRB2_SOS1_(complex) p21_RAS_GTP_(complex) GRB2 p21_RAS_GDP_(complex) Phosphorylated_SHC1_p46_and_p52_(family) KRAS GRB2_SOS1_(complex)
REACTOME_REACT_1884 gamma-H2AX_NBS1_complex_at_the_site_of_double-strand_break_(complex) H2AFX NBN
REACTOME_REACT_121337 Activated_FGFR3_cysteine_mutants_(complex) Activated_FGFR3c_P250R_mutant_(complex) FGFR3_point_mutant_dimers_with_enhanced_kinase_activity_(complex) FGFR3c_P250R_mutant_dimer_(complex) FGF2 FGFR3_cysteine_mutant_dimers_(complex) FGF18 FGF17 FGF16 FGFR3_cysteine_mutants_(family) FGFR3c-binding_FGFs_(family) phosphorylated_FGFR3c_P250R_mutant_dimer_(complex) FGF9 FGF8 FGF5 FGF4 FGFR3 FGF1 FGFR3c_P250R_mutant_dimer_bound_to_FGF_(complex) FGFR3_point_mutants_with_enhanced_kinase_activity_(family) Activated_FGFR3_mutants_with_enhanced_kinase_activity_(complex) FGF23 FGF20
REACTOME_REACT_20549 TP53 ubiquitinated_phospho-COP1(ser-387)_(complex) ubiquitin_(family) RPS27A UBA52 UBB UBC RFWD2 p-S15-TP53_Tetramer_(complex)
PID_cdc42_reg_pathway DOCK9 RALBP1 MCF2 DOCK6 PLCG1 FGD1 DOCK10 DOCK11 ARHGEF9 ARHGEF6 ARHGEF7 ITSN2 ARHGAP1 CDC42/GTP/DOCK11_(complex) ARHGDIA DNMBP SPATA13 FARP2 ASEF2/APC_(complex) PLCgamma1/betaPIX/GIT1_(complex) ITSN1 BCAR3 NGEF CDC42-GDP_(complex) NME1 RACGAP1 VAV3 VAV2 MCF2L ARHGAP17 GIT1 ARHGAP10 APC CDC42 ARHGEF25 CDC42-GTP_(complex)
PID_G_alpha__i__signalling_events Heterotrimeric_G-protein_Gi_(inactive)_(complex) GNAS GNB1 Heterotrimeric_G-protein_Gi_(active)_(complex) G-protein_alpha_(i) G-protein_beta-gamma_complex_(complex) G-protein_alpha_(i)__GTP_(complex) Ligand_GPCR_complexes_that_activate_Gi_Heterotrimeric_G-protein_Gi_(inactive)_(complex) Adenylate_cyclase G-protein_alpha_(s)_GTP_(complex) GNG2 G-protein_alpha_(z)_GTP_(complex) Gs-activated_adenylate_cyclase_(complex) Light-sensing_opsins GNAZ Adenylate_cyclase_(Mg2+_cofactor)_(complex) Ligand_GPCR_complexes_that_activate_Gi_Heterotrimeric_G-protein_Gi_(active)_(complex) G-protein_alpha_(i)_GDP_(complex) Opsins_photon_(complex) G-protein_alpha_(z)_GTP_Adenylate_cyclase_(complex) G-protein_alpha_(i)_GTP_Adenylate_cyclase_(complex)
BIOCYC_PWY-7176 NME4 NME5 NME6 CTPS1 CTPS2 NME2 NME3 CMPK1 CMPK2 NME7 NME2P1 nucleoside_diphosphate_kinase_(complex) NME1
PID_SHC_activation phospho-insulin_receptor_(complex) activated_insulin_receptor_(complex) SHC_activated_insulin_receptor_(complex) phospho-SHC__activated_insulin_receptor_(complex) Insulin_(complex) INS INSR SHC1
PID_E2F_mediated_regulation_of_DNA_replication E2F1_targets DP-1_E2F1_complex_(complex) E2F1 TFDP1
BIOCYC_PWY0-1296 PNP_(complex) ADAT3 ADA
REACTOME_REACT_2174 MAD2L2 UniProt_Q9UID5_hREV3 Pol_zeta_complex_(complex) Pol_zeta_damaged_DNA_template_complex_(complex)
REACTOME_REACT_1707 Orc2_associated_with_MCM8_(complex) ORC6 ORC4 ORC5 ORC2 ORC3 ORC1 CDC6 ORC_origin_(complex) CDC6_ORC_origin_complex_(complex) MCM8
REACTOME_REACT_63 RPC7/RPC7-like_(family) RNA_Polymerase_III_Holoenzyme_(complex) POLR3F POLR3G POLR3D POLR3E POLR1D POLR3C HsRPC4_HsRPC5_(complex) POLR3A POLR3K POLR3H Elongating_RNA_Polymerase_III_Transcription_Complex_(complex) LZTS1 POLR3GL POLR2E POLR2F POLR2L POLR2H POLR2K HsRPC6_HsRPC3_HsRPC7_(complex) HsRPC8_HsRPC9_(complex) POLR1C Paused_RNA_Polymerase_III_Transcription_Complex_(complex) POLR3B
REACTOME_REACT_20568 R-Ras-GTP_(complex) CREB1 RRAS Activated_B-raf_complex_(complex) MAPK1 BRAF
PID_Translesion_synthesis_by_HREV1 HREV1 HREV1_damaged_DNA_template_complex_(complex) HREV1_lesioned_DNA_template_with_misinserted_bases_(complex)
PID_Transport_of_the_SLBP_Dependant_Mature_mRNA NUP88 AAAS SLBP NCBP1 NCBP2 NUP85 Mature_intronless_transcript_derived_Histone_mRNA_SLBP_TAP_Aly/Ref_complex_(complex) Mature_intronless_transcript_derived_Histone_mRNA_SLBP_eIF4E_Complex_(complex) NUP62 NUP133 NUP98 NUP43 NUP188 NUP214 NUP210 RANBP2 POM121 NXF1 NUP107 Nup107_Complex_(complex) NUP160 NUP93 ALYREF TPR Nup62_Complex_(complex) NUPL1 NUPL2 EIF4E SEH1L NUP50 NUP54 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 Mature_Intronless_transcript_derived_Histone_mRNA_SLBP_CBP80_CBP20_(complex) NUP153 NUP155 NUP205 RAE1
PID_irespathway c-Myc_mRNA picornavirus_protease_2A EIF4G3 EIF3A EIF4G1 Active_caspases PTB eIF-4G/eIF-4E/PTB_(complex) eIF-4G/eIF3/EIF-4A_(complex) EIF4G2 EIF4E c-Myc_mRNA/eIF-4G_(dimer)/eIF-3/eIF-4E/eIF-4A/PTB_(complex) EIF4A1
REACTOME_REACT_6785 phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) RPS27A ANAPC10 UBIQ_HUMAN_(family) ANAPC2 CDC16 ANAPC11 phospho-Cdh1_phospho-APC/C_(complex) multiubiquitinated_Cdh1_associated_with_APC/C_(complex) UBE2E1 ANAPC1 UBE2D1 ANAPC5 ANAPC4 ANAPC7 CDC27 CDC26 UBE2C FZR1 CDC23 UBA52 UBB UBC
REACTOME_REACT_6258 UCP_(family) UCP_dimer_(complex) FA_anion_UCP_dimer__head-out__complex_(complex) UCP1 UCP2 UCP3 FA_anion_UCP_dimer__head-in__complex_(complex)
BIOCYC_LIPASYN-PWY PLCZ1 PLCD1 phospholipase_A2__group_IVB_(cytosolic) PLCG2 PLCG1 PLCE1 PLCH1 PLA2G1B OC90 PLCH2 PHOSPHATIDYLCHOLINE_2_ACYLHYDROLASE PLA2G5 PLA2G3 PNPLA8 PLCB1 PLCB2 PLCB3 PLCB4 PLD6 PLA2G2A PLCD4 PLA2G2E PLA2G2D PLB1 PLA2G4A PLA2G4F PLA2G4E PLA2G4D PLD4 PLA2G16 PLD1 PLD2 PLD3 PLA2G2F intracellular_membrane-associated_calcium-independent_phospholipase_A2_gamma PLC_BETA_PHOSPHOLIPASE_C_BETA PLCD3
PID_hedgehog_2pathway SHH_Np/Cholesterol/Hhip_(complex) LRPAP1 PI3K_(complex) Megalin/LRPAP1_(complex) PTHLH SMO AKT1 ARRB2 SMO/beta_Arrestin2_(complex) BOC ADRBK1 SMO/Vitamin_D3_(complex) SHH_Np/Cholesterol/PTCH1_(complex) STIL PIK3CA SHH_Np/Cholesterol/PTCH2_(complex) CDON GLI2 IHH_N/Hhip_(complex) Dnchc2 SHH_Np/Cholesterol/Megalin_(complex) DISP1 LRP2 HHAT PIK3R1 DHH SHH_Np/Cholesterol/BOC_(complex) PTCH2 GLI2A DHH_N/Hhip_(complex) IHH_N/PTCH2_(complex) IHH_N/PTCH1_(complex) DHH_N/PTCH1_(complex) SHH SHH_Np/Cholesterol/GAS1_(complex) IHH GAS1 SHH_Np/Cholesterol/CDO_(complex) DHH_N/PTCH2_(complex) PTCH1 SHH_Np/Cholesterol_(complex) HHIP
PID_tercpathway NF-Y_(complex) SP1 SP3 RB1 NFYC NFYB NFYA
REACTOME_REACT_15312 ADCY4 ADCY5 ADCY6 ADCY7 G_alpha-olf_GDP_Adenylate_cyclase_(active)_complex_(complex) ADCY1 ADCY2 ADCY3 ADCY8 ADCY9 G_alpha-olf_GDP_complex_(complex) Adenylate_cyclase_(family) GNAL G_alpha-olf_GTP_Adenylate_cyclase_(active)_complex_(complex) Adenylate_cyclase_(Mg2+_cofactor)_(complex) G_alpha-olf_GTP_(complex)
PID_mRNA_Splicing SRSF7 SRSF6 SRSF1 SRSF2
PANTHER_P00005 Complex_(eNOS/Ca2+_(complex) SPK Complex_(Tie2/Ang-1)_(complex) cPLA2 JNK1 Eph Ets Caspase-9 Src FRS-2 Complex_(Notch/Delta/_Serrate)_(complex) Grb14 BAD PDGF c-Fos Dsh CRK Delta/Serrate Pak c-Jun Fzd Complex_(cPLA2_endsub/Ca2+_endsuper)_(complex) STAT3 Complex_(FGFR-1/FGF)_(complex) GSK3beta PKC PLA2 VRAP Complex_(EphR/Eph)_(complex) GAP FAK Grb2 VEGF Grb7 Complex_(Wnt/Fzd)_(complex) TCF VEGFR-2 FGF CSL SHC Wnt PI3K MAPKAPK2/3 JAK1 HIF-1 SOS-1 Akt MEKK1 HSP27 GTPase Ang-1 Complex_(VEGFR-2/VEGF)_(complex) Complex_(c-Jun/c-Fos)_(complex) Dok-R Complex_(Axin/APC/_GSK3beta)_(complex) JNKK1 Notch PLC-gamma Erk Raf Survivin Axin STAT1 FGFR-1 Sck beta_catenin EphR Complex_(PDGFR/PDGF)_(complex) PDGFR MEK Rac PLD PAR Ras p38MAPK Tie2 APC Paxillin eNOS Nck CYP2A6
REACTOME_REACT_25216 IFNA/B_IFNAR2_p-JAK1_STAT2_p-IFNAR1_p-TYK2_p-STAT2_STAT1_(complex) p-STAT2_STAT1_(complex) IFNA/B_IFNAR2_JAK1_STAT2_(complex) IFNAR2 IFNAR1 IFNAR2_p-JAK1_STAT2_(complex) TYK2 IFNA/B_IFNAR2_p-JAK1_STAT2_IFNAR1_TYK2_(complex) STAT2 STAT1 p-STAT1_(family) IFNA/B_IFNAR2_JAK1_STAT2_IFNAR1_TYK2_(complex) STAT2_1_hetero_dimer_(complex) STAT1_alpha/beta_(family) JAK1 IFNAR2c_UBP43_(complex) IFNAR2_JAK1_STAT2_(complex) IFNAR1_TYK2_(complex) p-STAT2_p-STAT1_p-IFNAR1_p-TYK2_(complex) p-STAT2_STAT1_p-IFNAR1_p-TYK2_(complex) USP18 IFNA/B_IFNAR2_p-JAK1_STAT2_p-IFNAR1_p-TYK2_p-STAT2_p-STAT1_(complex) SOCS1 SOCS3 SOCS-1_and_SOCS-3_(family) p-IFNAR1_p-TYK2_SOCS-1/SOCS-3_(complex) p-TYK2_p-IFNAR1_SOCS-1/SOCS-3_IFNA/B_IFNAR2_p-JAK1_STAT2_(complex) IFNA/B_IFNAR2_p-JAK1_STAT2_(complex)
REACTOME_REACT_163660 UniProt_P05919_vpu Trimeric_ENV_precursor_(complex) gp120_homotrimer_(complex) EMBL_AF033819_EMBL_AF033819 UniProt_P04578_env Trimeric_gp120_gp41_oligomer_(complex) gp41_homotrimer_(complex)
PID_ARMS_mediated_activation NGF Active_TrkA_receptor_Phospho-ARMS_Crk_C3G_complex_(complex) C3G Phospho-ARMS_Crk_(complex) RAP1/GDP_(complex) Active_TrkA_Phospho-ARMS_Crk_C3G_Rap1_Phospho-B-Raf_complex_(complex) Active_TrkA_receptor_Phospho-ARMS_Crk_complex_(complex) Activated_TrkA_receptor_complex_(complex) RAP1A KIDINS220 Phospho-B-Raf_(complex) NTRK1 ARMS_Crk_(complex) BRAF CRK RAP1/GTP_(complex) beta-NGF_homodimer_(complex) Active_TrkA_receptor_ARMS_Crk_complex_(complex)
PID_vobesitypathway cortisol/glucocorticoid_receptor_(complex) NR3C1 RXRA PPARG LPL PPAR-gamma/RXR_(complex) cortisol/glucocorticoid_receptor/cortisol/glucocorticoid_receptor_(complex) HSD11B1
REACTOME_REACT_387 RPS13 RPS12 RPS11 RPS10 RPS17 EMBL_X03205 RPS15 RPS14 EIF3D RPS19 RPS18 RPS15A RPS7 RPS4X RPS5 EMBL_M13699 RPS27A RPS2 43S_mRNA_eIF4F_eIF4B_eIF4H_(complex) Met-tRNAi_eIF2_GTP_(complex) FAU EIF2S1 EIF2S3 EIF2S2 EIF3H EIF3I EIF3J EIF3K EIF3A EIF3B EIF3C EIF1AX EIF3E EIF3F EIF3G RPS9 PABPC1 RPS8 RPS16 RPS26 RPS27 RPS24 RPS25 RPS23 RPS20 RPS21 RPS28 RPS29 eIF2_subunit_complex_(complex) RPS4Y1 EIF4H EIF4E cap-binding_complex_(complex) EIF4B eIF2_GTP_(complex) eIF3_eIGF1A_40S_Met-tRNAi_eIF2_GTP_(complex) 43S__Ceruloplasmin_mRNA_eIF4F_eIF4B_eIF4H_PABP_(complex) RPSA RPS6 40S_ribosomal_complex_(complex) eIF3_subunits_complex_(complex) RPS3A eIF4A_subunits_complex_(complex) RPS3 EIF4A1 EIF4G1 EIF4A2
REACTOME_REACT_2232 UBF-1_rDNA_Promoter_(complex) Phosphorylated_UBF-1_rDNA_promoter_(complex) UBTF
REACTOME_REACT_111046 FGF19 FGFR4 Activated_FGFR4_bound_to_FGF19_BetaKlotho_(complex) KLB FGF19_bound_to_BetaKlotho_and_FGFR4_(complex)
Pathway_7d2f72265f1b153793f68d27f5b3f681.owl UDP-glucuronosyltransferase_(O-glucuronide_forming_isozymes) UGT1A4
PID_SHC_mediated_signalling SOS1 p21_RAS p21_RAS_GTP_(complex) GRB2 GRB2_SOS_Phospho-SHC_(complex) GRB2_SOS1_(complex)
REACTOME_REACT_13528 PAK-2p34_RHG10_complex_(complex) PAK2 ARHGAP10 perinuclear_PAK-2p34_RHG10_complex_(complex)
PID_aifpathway BCL2L1 AIFM1 PARP1
REACTOME_REACT_121155 Overexpressed_FGFR2_homodimers_GP369_(complex) Overexpressed_FGFR2_homodimers_(complex) Activated_overexpressed_FGFR2_dimers_(complex) Overexpressed_FGFR2_(family) FGFR2 Overexpressed_FGFR2_TKIs_(complex)
PID_integrin4_pathway alpha6/beta4_Integrin/Laminin_5_(complex) LAMA1 LAMA2 LAMA3 ITGB4 alpha6/beta4_Integrin/Laminin_1_(complex) ITGA6 LAMC2 LAMC1 alpha6/beta4_Integrin/Laminin_2_(complex) LAMB1 alpha6/beta4_Integrin/Laminin_10_(complex) LAMB3 LAMB2 alpha6/beta4_Integrin/Laminin_11_(complex) alpha6/beta4_Integrin/Laminin_4_(complex) LAMA5
PID_Opioid_Signalling OPRM1 Opioid_peptide Opioid_MOR_(complex)
PANTHER_P00051 coA
PID_Telomere_C_strand_synthesis_initiation POLA2 POLA1 RNA_primer_G-strand_extended_telomere_end_DNA_polymerase_alpha_primase_complex_(complex) DNA_polymerase_alpha_primase_(complex) DNA_Pol_alpha_primase_(complex) RNA_primer-DNA_primer_G-strand_extended_telomere_(complex) PRIM1 PRIM2
REACTOME_REACT_118682 MMP14 MMP13_intermediate_forms_(family) MMP16 MMP17 MMP10 MMP11 TIMP1 MMP13 MMP14_TIMP2_MMP2_intermediate_form_(complex) proMMP9_TIMP1_(complex) TIMP2 MMP15 MMP14_TIMP2_(complex) MMP14_TIMP_MMP2_(complex) MT-MMPs_(family) MMP13_intermediate_form_fragments_(family) MMP25 MMP24 MMP14_TIMP2_proMMP2_(complex) proMT-MMPs_(family) MMP8 MMP9 MMP7 MMP2 MMP3 MMP1
PID_ADP_signalling_through_P2Y_purinoceptor_1 MAPK14 Heterotrimeric_G-protein_Gq/11_(inactive)_(complex) SRC GNB1 G-protein_beta-gamma_complex_(complex) G-protein_alpha_(q/11)_GDP_(complex) ADP_P2Y_purinoceptor_1_G-protein_Gq_(inactive)_(complex) Heterotrimeric_G-protein_Gq_(active)_(complex) GNG2 ADP_P2Y_purinoceptor_1_(complex) G-protein_alpha_(q/11) P2RY1 G-protein_alpha_(q/11)__GTP_(complex) PLA2G4A ADP_P2Y_prurinoceptor_1_G-protein_Gq_(active)_(complex)
PANTHER_P00037 Complex_(EAAT/Glutamate)_(complex) NR2B NR2C PSD95 Complex_(SNARE_Complex/Ca2+)_(complex) NR2D KA3 KA2 KA1 KA5 KA4 NR1 AGT Complex_(mGluR_2/3/_Glutamate)_(complex) Vglut SERPINA1 SERPINA3 SERPINC1 Glu4 Glu2 Glu3 Glu1 Complex_(Glu4/Glu2/_Glu1)_(complex) C3 Complex_(Glu4/Glu3/_Glu2)_(complex) A/K Complex_(Vglut/Glutamate)_(complex) SNARE_Complex Complex_(KA/Glutamate)_(complex) KA s218_(complex) mGluR_2/3 Complex_(NMDA/PSD95)_(complex) s221_(complex)
PANTHER_P00056 VRAP BAD eNOS Complex_(cPLA2_endsub/Ca2+_endsuper)_(complex) PKC FAK SPK VEGF VEGFR-2 PLC-gamma Ets Complex_(eNOS/Ca2+_endsuper)_(complex) PI3K MAPKAPK2/3 Akt/PKB Caspase9 HSP27 Complex_(VEGFR-2/VEGF)_(complex) PKC/Ca2+_(complex) Erk Raf HIF-1 Rac Sck cPLA2 MEK p38MAPK Ras Paxillin
PANTHER_P06213 PUT_(complex) NEJ proDPP_(complex) TSG DIF LACK BABO_(complex) PUT/DPP_phosphoTKV_phosphoMAD_(complex) __(complex) SAX_(complex) phosphoTKV/_DPP/PUT_DAD_(complex) LV107_HUMAN SHN/MED/_phosphoMAD_(complex) SCW_(complex) KV206_HUMAN TL_(complex) DAD SPZ SOG FYN PUT/DPP_phosphoTKV_MAD_(complex) TKV TKV/DPP/_PUT_(complex) DPP_dimer/_TKV_(complex) MED/_phosphoMAD_(complex) SOG/TSG_DPP_dimer_(complex) IGF2 R-Smad MED phosphoMAD_LACK_(complex) WIT_(complex) activinbeta_full_length DPP_(complex) NEJ/MED/_phosphoMAD_(complex) SHN HV107_HUMAN TRIF_(complex) phosphoTKV/_DPP/PUT_(complex) Full-length_BMP_orthologous_ligand TGFbetaR_I_(complex) SMOX_(complex) MAD Co-Smad
BIOCYC_PWY3DJ-11281 sphingomyelin_deacylase SMPD3 ENPP7 SMPD4 SMPD1 SGMS2 SGMS1 SMPD2 SAMD8 neutral_sphingomyelinase
REACTOME_REACT_9058 linear_duplex_viral_DNA_(complex) UniProt_P04591_gag IN_bound_to_sticky_3prime_ends_of_viral_DNA_in_PIC_(complex) UniProt_P04585_gag-pol XRCC5 XRCC4 XRCC6 viral_PIC_proteins_(complex) Matrix_(family) LIG4 Ku_proteins_bound_to_viral_DNA_(complex) XRCC4_DNA_ligase_IV_complex_(complex) viral_DNA_Ku_proteins_XRCC4_DNA_ligase_IV_complex_(complex) HMGA1 UniProt_P04618_rev UniProt_P05919_vpu 2-LTR_form_of_circular_viral_DNA_(complex) Ku70_Ku80_heterodimer_(complex) IN_bound_to_sticky_3prime_ends_of_viral_DNA_(complex) viral_DNA_with_3prime_sticky_ends_(complex) PSIP1 UniProt_P69726_vpr UniProt_P69723_vif BANF1 p6_protein_(family)
PID_Adenylate_cyclase_inhibitory_pathway Gi_alpha1_GTP_(complex) Gi_alpha1_GDP_Adenylate_cyclase_G_alpha-olf_GDP_complex_(complex) G_alpha-olf_GDP_complex_(complex) Adenylate_cyclase Gi_alpha1_GDP_(complex) GNAL Adenylate_cyclase_(Mg2+_cofactor)_(complex) Gi_alpha1_GTP_Adenylate_cyclase_G_alpha-olf_GDP_complex_(complex) Gi_alpha1_GTP_Adenylate_cyclase_G_alpha-olf_GTP_complex_(complex) Gi_alpha1_GTP_Adenylate_cyclase_complex_(complex) G_alpha-olf_GTP_complex_(complex) GNAI1
PID_G_protein_activation G_protein_alpha_GDP_complex_(complex) G_protein-GTP_(complex) G-protein_alpha_(i/o/z/t)_subunit G-protein_alpha_GDP_(complex) Opioid_peptide GNB1 G-protein_beta-gamma_complex_(complex) Heterotrimeric_G-protein_(complex) Opioid_MOR_G-protein_complex_(complex) G_protein_alpha_GTP_complex_(complex) G_protein-GDP_complex_(complex) OPRM1 GNG2 Opioid_MOR_(complex) Opioid_MOR_G_protein-GTP_complex_(complex) Opioid_MOR_G_protein-GDP_complex_(complex)
PID_mRNA_Editing__C_to_U_Conversion APOBEC1 C_to_U_edited_ApoB_RNA_Editosome_complex_(complex) ACF
REACTOME_REACT_13464 ubiquitin_(family) RPS27A UBA52 UBB UBC PAK2
PID_carmerpathway ESR1 p300/CBP_(complex) Estrogen_receptor_inhibitors Estrogen/ER_alpha_(complex) CARM1 Estrogen_receptor_activators Estrogen/ER_alpha/Estrogen/ER_alpha/GRIP1/CARM1/p300(Me)/CBP(Me)_(complex) GRIP1 Estrogen/Estrogen/ER_alpha/ER_alpha_(complex) EP300 CREBBP
REACTOME_REACT_6850 MAD2L1 BUB1B phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) UBE2D1 CCNA2 CCNA1 ANAPC11 ANAPC10 Cyclin_A_phospho-Cdc2(Thr_161)_complex_(complex) MCC_APC/C_complex_(complex) BUB3 Cdc2_Cyclin_A_MCC_APC/C_complex_(complex) UBE2E1 Cyclin_A_(family) ANAPC1 CDC16 ANAPC2 ANAPC5 ANAPC4 ANAPC7 multiubiquitinated_Cyclin_A_associated_with_MCC_APC/C_complex_(complex) CDC27 CDC26 UBE2C CDC23 CDC20 CDK1 UBA52 hBUBR1_hBUB3_MAD2__CDC20_complex_(complex) UBB UBC ubiquitin_(family)
PANTHER_P04395 Signal_Peptide Pro-Vasopressin Vasopressin Pro-Neurophysin Neurophysin Complex_(Neurophysin/Glycopeptide)_(complex) Complex_(Vasopressin/Neurophysin/_Glycopeptide)_(complex) Complex_(Lysine/Arginine)_(complex) Pro2-Vasopressin Glycopeptide
PID_Lysosphingolipid_and_LPA_receptors S1P-binding_EDG_receptors__S1P_(complex) LPA-binding_EDG_receptors S1P-binding_EDG_receptors LPA-binding_EDG_receptors__LPA_(complex)
PID_Terminal_pathway_of_complement C5b_(complex) C5b_C6_complex_(complex) C5b_C6_C7_C8__12xC9_membrane_attack_complex_(complex) C9 C8_(complex) C8A C8B C5b_C6_C7_C8_complex_(complex) C8G C5b_C6_C7_complex_(complex) C7 C6 C5
PID_TRAM_Cascade IRF3 TICAM1 TICAM2 TRAM_activated_TLR4_(complex) TBK1 TLR4_MD2_complex_(complex) TRIF_TRAM_activated_TLR4_(complex) RIPK1 LPS_bound_to_the_signal-competent_TLR4_complex_(complex) TLR4 LY96 IRF3-P_IRF3-P_(complex) RIP1_TRIF_TRAM_activated_TLR4_(complex)
PID_dreampathway RPS6KA3 Dynorphin/Kappa_opoid_receptor_(complex) CREB1 FOS JUN c-FOS/c-JUN/CREB/CREB_(complex) DREAM/DREAM/DREAM/DREAM_(complex) Dynorphin PRKAR2A MAPK3 PRKACG PRKAR2B CREM PRKAR1B PRKACB OPRK1 PKA_(complex) KCNIP3 PRKAR1A
PID_mitochondrial_fatty_acid_beta_oxidation_of_saturated_fatty_acids HADH ACADS HADHB LCAD_acyl-CoA_dehydrogenase_homotetramer_(complex) HADHA enoyl-CoA_hydratase_hexamer_(complex) MCAD_acyl-CoA_dehydrogenase_homotetramer_(complex) short_chain_3-hydroxyacyl-CoA_dehydrogenase_homodimer_(complex) ECHS1 Trifunctional_Protein_(complex) SCAD_acyl-CoA_dehydrogenase_homotetramer_(complex) ACADL ACADM
PID_Axonal_growth_stimulation NGF RhoA_(Mg_cofactor)_GDP_(complex) mature_beta-NGF_homodimer_(complex) ARHGEF1 RhoA_(Mg_cofactor)_GTP_(complex) NGFR RhoA_Rho-GDIalpha_p75NTR_NGF_(complex) ARHGDIA RHOA RHOA_RHO-GDIalpha_p75NTR_(complex)
PID_PI_3K_cascade PI3K-catalytic_subunit Activated_FGFR_bound_to_PI3K_(complex) GRB2_and_GAB1_bound_to_activated_FGFR_and_FRS2-alpha_(complex) PI3K_(complex) PTPN11 Activated_FGFR_p-FRS2-alpha_p-SHP2_(complex) GAB1 GRB2 Activated_FGFR_p-FRS2-alpha_(complex) FRS2 PI3K-regulatory_subunit
BIOCYC_PWY66-5 MSMO1 TM7SF2 NSDHL IDI1 IDI2 DHCR7 SC5D GGPS1 farnesyl_pyrophosphate_synthetase_FPP_synthetase_FPS_farnesyl_diphosphate_synthetase SQLE LBR <i>E</i>-farnesyl_diphosphate_synthase_(complex) HADHB mevalonate_kinase_(complex) ACAT1 ACAT2 LSS CYP51A1 mitochondrial_acetyl-CoA_acetyltransferase_(complex) FDFT1 cytosolic_acetyl-CoA_acetyltransferase_(complex) HSD17B7 HMGCS1 hydroxymethylglutaryl-CoA_synthase_(complex) 3-hydroxy-3-methylglutaryl-coenzyme_A_reductase_(complex) geranylgeranyl_pyrophosphate_synthetase_(complex) MVD HMGCR sterol_8-isomerase_(complex) MVK DHCR24 FDPS PMVK EBP diphosphomevalonate_decarboxylase_(complex)
PID_cd40pathway CD40/CD40L_(complex) CD40LG MAP4K4 TRAF6 NF-kappa-B_activators CD40/CD40L/TRAF3/TRAF6_(complex) MAP3K1 CD40 TNFAIP3 TRAF3
PID_CD28_dependent_Vav1_pathway CD28 RAC1 VAV1 PAK_bound_to_Rac1_and_Cdc42_(complex) CD28_Grb2_(complex) pVav1_PIP3_Grb2_CD28_(complex) FYN Vav1_bound_to_PIP3_and_Grb2_CD28_(complex) CD86 PAK CDC42-GTP_(complex) GRB2 Phospho_CD28_homodimer_(complex) phospho_CD28_B7-1/B7-2_(complex) RAC1-GDP_(complex) RAC1-GTP_(complex) Lck/Fyn CDC42
REACTOME_REACT_121042 MT1982 trxB1 TrxA/B1_(ox.)_(family) TrxA/B1_(family) trxA UniProt_P0A5N4_ahpD UniProt_Q7BHK8_ahpC MTCY190.26
PID_MicroRNA__miRNA__Biogenesis Ran-GTP_(complex) DGCR8 DROSHA XPO5 RAN Ran_GTP_Exportin-5_(complex) pre-miRNA_Ran_GTP_Exportin-5_(complex) Argonaute MicroProcessor_Complex_(complex) Ran_GTP_(complex) RNA_Polymerase_II_holoenzyme_complex_(generic)_(complex) POLR2E POLR2D POLR2G POLR2F POLR2A POLR2C POLR2B POLR2L POLR2I POLR2H POLR2K POLR2J DICER1 RISC_Loading_Complex_(microRNA)_(complex) TARBP2
PID_FGFR2_ligand_binding_and_activation GRB2 SDC2 Activated_FGFR_complexed_with_phosphorylated_FRS2__GRB2_and_CBL_(complex) CBL Phospho-FRS2
PID_Mitochondrial_transcription_initiation POLRMT_TFB2M_TFAM_mitochondrial_promoter_complex_(complex) TFAM TFB2M POLRMT_TFB2M_complex_(complex) TFAM_mitochondrial_promoter_complex_(complex) POLRMT
PID_ecmpathway ACTA1 PI3K_(complex) ECM/Integrin-alpha/Integrin-betaTalin/Calpain1/actin_(active1)/p130cas/FAK/CSK/Paxillin/Vinculin/alp_(complex) ROCK1 MAP2K1 ARHGAP5 ECM/Integrin-alpha/Integrin-betaTalin/Calpain1/actin/p130cas/FAK/CSK/Paxillin/Vinculin/alpha-actinin_(complex) ZYX GSN PIK3CA ECM TLN1 MAPK3 MAPK1 PXN CAPN1 ITGA1 TNS1 Rho-Kinase_Dia/Profilin_(complex) Alpha-actinin ITGB1 SRC DIAPH1 CSK VCL PIK3R1 RHOA BCAR1 PIP2/Gelsolin_(complex) MYLK PLCG1 PFN1 MLC1
PANTHER_P00004 HAC1 LRP_intracellular_fragment Fe65 Nectin_1alpha_transmembrane_fragment Complex_(E-cadherin/beta-catenin/_gammacatenin/alphacatenin/_actin)_(complex) Notch_fragment Aph-1 CYB5A Ire-1 actin Nectin_1alpha_N-terminal_fragment Notch_C-terminal_fragment Complex_(Notch_N-terminal_fragment/Notch_extracellular_fragment)_(complex) Dsh Presenilin Erb-B4 Frizzled Complex_(CSL/NICD)_(complex) Presenilin_N-terminal_fragment Afadin E-cadherin_N-terminal_fragment Complex_(LRP_intracellular_fragment/Fe65)_(complex) BACE-1_pro-domain E-cadherin_transmembrane_fragment Complex_(APP/Fe65)_(complex) E-cadherin Pen-2 Notch Complex_(AICD/Fe65)_(complex) Ire-1_C-terminal_fragment LRP_N-terminal_fragment Wnt Nicastrin LRP Nectin_1alpha_intracellular_fragment Tip60 CSL Complex_(Nicastrin/Aph-1/_Pen-2/Presenilin_N-terminal_fragment/_Presenilin_C-terminal_fragment)_(complex) Erb-B4_intracellular_fragment gammacatenin Complex_(Wnt/Frizzled)_(complex) E-cadherin_intracellular_fragment MT-CYB CD44 CD44_C-terminal_fragment Erb-B4_transmembrane_fragment C99 LRP_C-terminal_fragment LRP_transmembrane_fragment TCF/LEF Ire-1_N-terminal_fragment Abeta AICD Erb-B4_N-terminal_fragment GSK-3beta Complex_(beta-catenin/TCF/_LEF)_(complex) APPbeta Pro-BACE-1 E-cadherin_C-terminal_fragment BACE-1 Complex_(Nectin_1alpha/Afadin/_alphacatenin/actin/_beta-catenin/gammacatenin/_E-cadherin)_(complex) Notch_N-terminal_fragment Nectin_1alpha_C-terminal_fragment Notch_extracellular_fragment APP Nectin_1alpha Complex_(AICD/Fe65/_Tip60)_(complex) CD44_N-terminal_fragment Complex_(Notch_N-terminal_fragment/Notch_C-terminal_fragment)_(complex) Capacitative_calcium_channels NICD Notch_transmembrane_fragment Erb-B4_C-terminal_fragment Complex_(C99/Fe65)_(complex) CD44_intracellular_fragment Presenilin_C-terminal_fragment
PID_Activation_of_the_AP_1_family_of_transcription_factors Activated_Protein_1_(AP-1)_heterodimer_cJUN/ATF2_(complex) FOS Activated_MAPK_kinases_ERK1/2__JNK__p38 JUN Phosphorylated_JNKs__MAPK8__MAPK9__MAPK10 Activated_Protein_1_(AP-1)_heterodimer_cJUN/cFOS_(complex) ATF2
PID_NEP_NS2_Interacts_with_the_Cellular_Export_Machinery NUP88 AAAS UniProt_P03433_PA NUP133 vRNA_(Genomic)_NP_Complex_(complex) NUP85 vRNP_M1_for_Export_(complex) vRNP_Export_Complex_(complex) UniProt_P03428_PB2 XPO1 NUP62 SEH1L vRNP_M1_NEP_NP_(complex) NUP98 NUP43 NUP188 UniProt_P03485_M UniProt_P03466_NP NUP214 UniProt_P03431_PB1 NUP210 vRNP_M1_NEP_(complex) RANBP2 UniProt_P03508_NS POM121 NUP107 Nup107_Complex_(complex) NUP160 NUP93 TPR Nup62_Complex_(complex) NUPL1 NUPL2 Genomic_RNA_Segment_5 Genomic_RNA_Segment_3 NUP50 NUP54 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 NUP153 NUP155 vRNP_destined_for_Export_(complex) NUP205 RAE1
BIOCYC_GLUTATHIONESYN-PWY glutamate--cysteine_ligase_(complex) GCLM GSS_(complex) GCLC
REACTOME_REACT_6354 vRNA_polymerase_host_mRNA_complex_(complex) UniProt_P03428_PB2 Elongated_vRNA-mRNA_Complex_(complex) Initiated_vRNA_Transcription_Complex_(complex) vRNA_(Genomic)_NP_Complex_(complex) UniProt_P03466_NP EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 Viral_RNA_dependent_RNA_polymerase_(complex) EMBL_J02150_NS2_mRNA UniProt_P03433_PA EMBL_J02150_NS1_mRNA UniProt_P03431_PB1
PID_Cyclin_A_B1_associated_events_during_G2_M_transition Cyclin_B1_phospho-Cdc2(Thr_161)_(complex) PKMYT1 Cyclin_A_phospho-Cdc2(Thr_161__Thr_14__Tyr_15)_(complex) Phospho-Cyclin_B1_(CRS)_phospho-Cdc2(Thr_161)_(complex) XPO1 phospho-Cyclin_B1(CRS)_phospho-Cdc2_(Thr_161)_(complex) Cyclin_A_Cdc2_(complex) Cyclin_A_phospho-Cdc2(Thr_14)_(complex) Cyclin_B_phospho-Cdc2(Thr_14)_(complex) Cyclin_B Cyclin_B_Cdc2_complex_(complex) Cyclin_B1_phospho-Cdc2(Thr_161__Thr_14__Tyr_15)_(complex) CDC25C CDC25B nuclear_Cyclin_B1_phospho-Cdc2_(_Thr_14)_complexes_(complex) Cyclin_A_phospho-Cdc2(Thr_161)_(complex) Cyclin_A_phospho-Cdc2(Thr_14__Thr_161)_(complex) MNAT1 WEE1 CCNB1 Cdc25 phospho-Cdc2(Thr_14)_Cyclin_A_(complex) CDK1 Cyclin_B1_phospho-Cdc2_(Thr_14__Thr_161)_(complex) CDK7 CAK_(complex) CCNH
REACTOME_REACT_18274 PRKAR1B GLP-1__GLP-1R__Heterotrimeric_G(s)__GTP_(complex) RAPGEF4 IQGAP1 KCNG2 G-protein_gamma_subunit_(candidates)_(family) RAP1A PRKAR2A Adenylyl_cyclase_(pancreatic_beta_cell)_(family) Ca-channel_(open)_(complex) Adenylate_cyclase__G-protein_alpha_(s)__GTP_Complex_(complex) GNG12 RAPGEF3 G-protein_beta_gamma_Complex_(candidates)_(complex) RAP1/GTP_(complex) G-protein_beta_subunit_(candidates)_(family) G-protein_alpha_(s)_GDP_(complex) mature_Glucagon-like_Peptide-1_(family) KCNC2 Potassium_voltage-gated_channels_(beta_cell__closed)_(family) GNG10 GNG11 GNB4 GNG13 GLP1R GNG2 GNGT2 GCG AKAP5 GNB5 Ca-channel_(closed)_(complex) KCNS3 GNB1 GNB3 GNB2 G-protein_alpha_(s)_GTP_(complex) RAP1B PRKAR1A GLP-1__GLP-1R__Heterotrimeric_G(s)__GDP_(complex) PRKAR2B KCNB1 Potassium_voltage-gated_channels_(beta_cell__open)_(family) RAP1_(family) RAPGEF4_cAMP_Complex_(complex) cAMP_PKA_regulatory_subunit_(complex) ADCY5 ADCY6 cAMP_PKA_AKAP79_IQGAP1_Complex_(complex) PKA_regulatory_subunit_(family) GNAS RAP1/GDP_(complex) ADCY8 GNG7 GNG4 GNG5 GLP-1_bound_to_GLP-1_Receptor_(complex) GNG3 GNGT1 RAPGEF3_cAMP_complex_(complex) GNG8
REACTOME_REACT_115662 USP8 ERBB3 Ub-NRDP1_P-USP8_(complex) ubiquitin_(family) RPS27A NRG1/2_Ub-p-10Y-ERBB3_p-ERBB2_(complex) RNF41 Ub-ERBB3_(complex) ERBB3_NRDP1_(complex) UBA52 Ub-NRDP1_(complex) UBB UBC Phosphorylated_ERBB2_ERBB3_heterodimers_(complex) NRG1/2_p-10Y-ERBB3_p-ERBB2_RNF41_(complex)
PID_ranbp2pathway2 HDAC1 HDAC4 HDAC6 HDAC9 SUMO1/MITR_(complex) Ran/GTP/Exportin/HDAC_(complex) SUMO1/HDAC4_(complex) Ran/GTP/Exportin/HDAC4_(complex) MDM2/SUMO1_(complex) Exportin SUMO1/HDAC_(complex) NUP153 NUP62 RAN SUMO1 NUP214 Ran/GTP/Exportin_(complex) NUP210 RANBP2 Ran/GTP/Exportin/HDAC6_(complex) NPC_(complex) MDM2 Ran/GTP/Exportin/MITR_(complex) MDM2/SUMO1/SUMO1_(complex) PIAS2 PIAS1
REACTOME_REACT_993 MUT 2xMMAA_(complex) MUT_dimer_apoenzyme_(complex) 2xMMAA_2xMUT_AdoCbl_(complex) methylmalonyl-CoA_mutase__homodimer_(complex) 2xMMAA_2xMUT_(complex) MMAA
REACTOME_REACT_1050 pro-factor_X_(complex) F2 PROZ pro-protein_C_(complex) F7 F9 pro-factor_X__uncarboxylated_(complex) PROS1 F10 pro-protein_C__uncarboxylated_(complex) PROC GAS6
PID_Sema4D_mediated_inhibition_of_cell_attachment_and_migration RRAS PLXNB1 RhoA_(Mg_cofactor)_GDP_(complex) Sema4D_pPlexin-B1_Met_(complex) Sema4D_pPlexin-B1_Met_RAC1-GTP_(complex) RAC1 Sema4D_Plexin-B1_p190RhoGAP_Rac_Rnd1_(complex) RhoA_(Mg_cofactor)_GTP_(complex) pPlexin-B1_Met_(complex) Sema4D_pPlexin-B1_Met_Rnd1_(complex) Rnd1-GTP_(complex) R-Ras-GDP_(complex) MET SEMA4D_dimer_(complex) RND1 Plexin-B1_Met_(complex) ARHGAP35 RAC1-GTP_(complex) RHOA SEMA4D
REACTOME_REACT_1036 TFIIIC_Type_2_Promoter_Complex_(complex) RPC7/RPC7-like_(family) GTF3C4 GTF3C3 GTF3C2 POLR3D POLR1C POLR1D POLR3C GTF3C5 POLR3A POLR3K POLR3H RNA_Polymerase_III_TFIIIB_TFIIIC_Type_2_Open_Promoter_Complex_(complex) TFIIIB_TFIIIC_Type_2_Promoter_Complex_(complex) BDP1 LZTS1 RNA_Polymerase_III_Holoenzyme_(complex) RNA_Polymerase_III_TFIIIB_TFIIIC_Type_2_Promoter_Complex_(complex) POLR3GL POLR2E POLR2F POLR2L BRF1 POLR2H POLR2K POLR3F TFIIIB-Type_1_and_2_Promoter_Selective_Complex_(complex) HsRPC6_HsRPC3_HsRPC7_(complex) POLR3G TBP GTF3C1 HsRPC4_HsRPC5_(complex) HsRPC8_HsRPC9_(complex) POLR3E TFIIIC_(complex) POLR3B
PID_Gab1_signalosome PAG1 GRB2_Phospho_GAB1-EGF-Phospho-EGFR_dimer_(complex) EGFR GAB1 EGF GRB2_GAB1_(complex) EGF_Phospho-EGFR-GRB2_GAB1_PI3Kreg_(complex) PIK3CA PXN PIK3R1 EGF_Phospho-EGFR-GRB2_GAB1_PI3Kreg_PI3Kcat_(complex) SHP2_GRB2_Phospho_GAB1-EGF-Phospho-EGFR_(-Y992)_dimer_(complex) SRC EGF_Phospho-EGFR_(-Y992)_dimer_(complex) PIP3_GAB1_GRB2-EGF-Phospho-EGFR_dimer_(complex) EGF_Phospho-EGFR_(complex) GRB2_Phospho-GAB1(partially_dephosphorylated)_(complex) SHP2-GRB2_Phospho_GAB1(dephos)-EGF-Phospho-EGFR_dimer_(complex) GRB2_Phospho-GAB1_(complex) SHP2-GRB2_Phospho_GAB1-EGF-Phospho-EGFR_dimer_(complex) EGF_Phospho-EGFR_(Y992__Y1068__Y1086__Y1148__Y1173)_dimer_(complex) PTPN11 GAB1_GRB2-EGF-Phospho-EGFR_dimer_(complex) EGF_Phospho-EGFR_(-_Y992)_(complex) GRB2 GRB2_GAB1_PI3Kreg_(complex) Paxillin_Src_complex_(complex)
BIOCYC_PWY66-393 PTGS2 ALOX5
REACTOME_REACT_22201 Cap_Binding_Complex_(CBC)_(complex) HIV-1_early_elongation_complex_with_hyperphosphorylated_Pol_II_CTD_(complex) NCBP1 NCBP2 NELFB P-TEFb_complex_(complex) ERCC2 ERCC3 CTDP1 POLR2B RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex) TCEB3 CCNT1 Elongin_B_C_complex_(complex) NELFE CCNT2 RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) SUPT5H SSRP1 TCEB2 FACT_complex_(complex) TCEA1 Elongin_Complex_(complex) SUPT16H NELFA ELL GTF2H3 GTF2H2 GTF2H1 TCEB1 GTF2H4 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C CDK9 POLR2L MNAT1 HIV-1_elongation_complex_(complex) POLR2I POLR2H POLR2K POLR2J GTF2F1 NELFCD GTF2F2 NELF_complex_(complex) TFIIH_(complex) SUPT4H1 CDK7 DSIF_complex_(complex) CAK_(complex) CCNH
PANTHER_P00055 Complex_(CREB/CBP/_P300)_(complex) Complex_(TFIIF/RNA_Polymerase_II)_(complex) TTF2 Complex_(TBP-associated_factors/TBP/_TATA_box_Promoter/TFIIB/_TFIIA_complex)_(complex) __(complex) HV209_HUMAN s161_(complex) Complex_(Receptor/hormone)_(complex) TFIIF s173_(complex) PKA TFIIH_complex TFIIFbeta TFIIE TBP-associated_factors Complex_(TBP/TBP-associated_factors)_(complex) IGF2 Complex_(TATA_box_Promoter/TBP/_TBP-associated_factors/TFIIA_complex/_TFIIH_complex/TFIIB/_RNA_Polymerase_II/TFIIF/_TFIIE)_(complex) hormone MAD_(complex) RNA_Polymerase_II CREB_(complex) WIT_(complex) s168_(complex) s169_(complex) s181_(complex) TFIIFalpha TRIF_(complex) Complex_(TATA_box_Promoter/RNA_Polymerase_II/_TFIIF/TBP/_TBP-associated_factors/TFIIH_complex/_TFIIA_complex/TFIIB)_(complex) s170_(complex) Complex_(CBP/P300/_CREB)_(complex) Complex_(TBP-associated_factors/TBP/_TATA_box_Promoter/TFIIA_complex)_(complex) TFIIB Receptor TBP TFIIA_complex s160_(complex) Complex_(TBP-associated_factors/TBP)_(complex) CBP/P300
REACTOME_REACT_15530 Cam-PDE_1_homodimer_(complex) active_Cam-PDE_1_(complex)
PID_Lipoprotein_metabolism CETP CETP_cholesterol_ester_complex_(complex) LDLR APOC2 APOC3 CETP_triacylglycerol_complex_(complex) LDLRAP1
BIOCYC_GLUDEG-I-PWY GAD_KDA_GLUTAMIC_ACID_DECARBOXYLASE NAD-dependent_succinate_semialdehyde_dehydrogenase_(complex) GAD-65_(complex) GAD-67_(complex) ABAT ALDH5A1 GABA-T_(complex) GAD1 GAD2
PID_crebpathway NT_(neurotransmitter) PI3K_(complex) HRAS MAPK14 AKT1 PRKAR2B NT/GPCR/AC/G-alpha-s_(complex) PIK3CA SHC/GRB2/SOS-1_(complex) GPCR ERK1/ERK2 PKC CaM/Ca_++_(complex) PIK3R1 AC SHC1 RPS6KA1 CREB1 GF PRKAR1A PRKAR1B G-alpha-S CREB/CREB_(complex) PRKAR2A CAMKII/CaM/Ca_++/CaM/Ca_++_(complex) GF_R RPS6KA5 SOS1 PKA_(complex) GF/GF_R_(complex) CAMKII PRKACG GRB2 CaM PRKACB CAMKII/CaM/Ca_++/CaM/Ca_++/CaM/Ca_++/CaM/Ca_++_(complex)
PID_rhoa_reg_pathway OBSCN MCF2 CDKN1B SRGAP1 TRIO OPHN1 ARHGAP8 ARHGAP9 ARHGAP4 ARHGAP5 ARHGAP6 ARHGEF10L BCR ARAP3 DEF6 ARAP1 ARHGEF5 ARHGEF2 ARHGEF3 FARP1 ARHGEF1 ARHGDIG ARHGDIB ARHGDIA DLC1 NET1 MYO9B ARHGEF10 ARHGEF11 ARHGEF12 NGEF ARHGEF15 ARHGEF17 ARHGEF18 RHOA/GTP_(complex) RICS ABR RhoA/GDP/Rho_GDI_gamma_(complex) RHOA RhoA/GDP/RHOGDI_(complex) RhoA/GDP/Rho_GDI_beta_(complex) PLEKHG6 ECT2 smgGDS VAV1 VAV3 VAV2 MCF2L RhoA/GTP/RHOGDI_(complex) ARHGEF28 ARHGAP35 RHOA/GDP_(complex) ARHGEF25 AKAP13
REACTOME_REACT_163938 CD9_Izumo_(complex) Izumo_(family) IZUMO1 IZUMO2 IZUMO3 IZUMO4 CD9
PID_Tat_mediated_HIV_1_elongation_arrest_and_recovery_ HIV-1_Tat-containing_arrested_processive_elongation_complex_(complex) NELFB TCEB2 TCEB1 NELFA NELFE TCEB3 HIV-1_Tat-containing_processive_elongation_complex_(complex) CCNT1 Elongin_B_C_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) P-TEFb(Cyclin_T1_Cdk9)_complex_(complex) SSRP1 phospho-Spt5 CDK9 FACT_complex_(complex) Tat_P-TEFb(Cyclin_T1_Cdk9)_complex_(complex) ELL SUPT16H Elongin_Complex_(complex) TCEA1 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B TAT_protein POLR2L CTDP1 POLR2I POLR2H POLR2K POLR2J GTF2F1 NELFCD GTF2F2 NELF_complex_(complex) SUPT4H1 HIV-1_aborted_elongation_complex_after_arrest_(complex) DSIF_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex)
REACTOME_REACT_160255 p-RAB1_(family) p-T216_S189_S274_S373-GORASP1_p-S37-GOLGA2_p-RAB1_GTP_PLK1_(complex) RAB2A PLK1 GORASP2 BLZF1 RAB1B RAB2A_GTP_(complex) USO1_homodimer_(complex) RAB1A GOLGA2 USO1 p-T216_S274_S373-GORASP1_p-S37-GOLGA2_p-RAB1_GTP_(complex) p-T216_S274_S373-GORASP1_p-S37-GOLGA2_p-RAB1_GTP_PLK1_(complex) p-T222_225-GORASP2_BLZF1_RAB2A_GTP_(complex) GORASP1 GORASP2_BLZF1_RAB2A_GTP_(complex) p-RAB1_GTP_(complex)
PID_tollpathway TLR2/TLR6_activating_compounds/TLR2/TLR6/MYD88/IRAK/CD14_(complex) Poly_(I_c)TLR3/TLR3/MYD88/IRAK_(complex) PGN/PGRP_(complex) MAP2K3 TLR6 PGLYRP1 MAP2K6 MAP2K4 TLR9 MAPK14 TIRAP TLR2/TLR_6_activating_compounds MAP3K1 JUN MAP3K7 CpG_DNA/TLR9/TLR9/MYD88/IRAK_(complex) Imiquimod/TLR7/TLR7/MYD88/IRAK_(complex) MAPK8 IRAK1 TRAF6 FOS CHUK TLR2/TLR6_activating_compounds/TLR2/TLR2/MYD88/IRAK/CD14_(complex) LPS/TLR4/TLR4/TIRAP/TOLLIP/PKR/MYD88/IRAK/MD-2/CD14_(complex) ECSIT PPARA LY96 IKK2/IKK3/IKK1_(complex) p50 RELA Tak1/TAB1/TAB2_(complex) IKBKB R848/TLR7/TLR7/MYD88/IRAK_(complex) AP-1_(complex) MYD88 TOLLIP TAB2 TAB1 EIF2AK2 TLR2 TLR3 CD14 ELK1 MAP3K14 TLR7 TLR4 NF-kappa-B_(complex) IKBKG
PID_GPCR_downstream_signaling GNAS GNB1 G-protein_alpha_(i) G-protein_beta-gamma_complex_(complex) G-protein_alpha_(i)__GTP_(complex) Adenylate_cyclase G-protein_alpha_(s)_GTP_(complex) GNG2 G-protein_alpha_(z)_GTP_(complex) Gs-activated_adenylate_cyclase_(complex) GNAZ Adenylate_cyclase_(Mg2+_cofactor)_(complex) G-protein_alpha_(z)_GTP_Adenylate_cyclase_(complex) G-protein_alpha_(i)_GTP_Adenylate_cyclase_(complex)
PID_aktpathway NF-kappa-B_(complex) GH1 GHR 14-3-3/Forkhead_Transcription_Factors_(complex) PPP2CA PI3K_(complex) CHUK p50 CASP9 HSP90/AKT_(complex) AKT1 BAD PIK3CA PIK3R1 PDPK1 HSP90AA1 RELA GH/GH_R_(complex) Forkhead_Transcription_Factors YWHAH
PID_Regulation_of_DNA_replication UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76
REACTOME_REACT_6820 Cyclin_B1_phospho-Cdc2(Thr_161)_(complex) phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) RPS27A UBE2D1 CDC16 ANAPC11 ANAPC10 UBE2E1 CCNB1 CDC20_Phospho-APC/C_(complex) ANAPC1 ANAPC2 ANAPC5 ANAPC4 ANAPC7 Cdc20_phospho-APC/C_Cyclin_B_Cdc2_complex_(complex) CDC27 CDC26 UBE2C CDC23 CDC20 CDK1 UBA52 UBC multiubiquitinated_Cyclin_B_Cdc2_Cdc20_phospho-APC/C_complex_(complex) ubiquitin_(family)
PID_mcmpathway Cyclin_E/CDK2/p27_(complex) ORC/CDC6/CDT1/Cyclin_E/CDK2/p27_(complex) CDKN1B CDC6 ORC/CDC6/CDT1/Mcm2-7/SCF_(complex) CCNE1 CDT1 ORC/CDC6/CDT1_(complex) ORC/CDC6/CDT1/Mcm2-7_(complex) ORC6 ORC4 ORC5 ORC2 ORC3 ORC1 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2 KITLG CDK2
PID_Cyclin_D_associated_events_in_G1 Cyclin_D_Cdk4/6_p21/p27_(complex) Cyclin_D_phospho-CDK4/6_p21/p27_(complex) CDK4-6 CCND1 INK4A MNAT1 Cdk4/6_INK4A_complex_(complex) CDK4 CDK7 p21/p27 CAK_(complex) CCNH Cyclin_D_CDK4/6_p21/p27_complex_(complex)
REACTOME_REACT_23767 KCNMB1 KCNMB3 KCNMB2 KCNMB4 BK_channel_beta_subunit_(family) Phosphorylated_IRAG_IP3_receptor_type_1_(complex) KCNMA1 BK_channel__phophorylated_(complex) MRVI1 PRKG2 Cyclic_GMP-dependent_protein_kinases_(PKGs)_(family) PRKG1 ITPR1 Activated_cGMP-dependent_protein_kinase_(PKGs)_(complex)
PANTHER_P04378 HLA-DPB1 AC PKA G-Protein Complex_(GDP/G-Protein/_brBetasub_2/Epinephrine)_(complex)
REACTOME_REACT_1123 PDE3B
REACTOME_REACT_163734 STAT6 TBK1 STING_TBK1_STAT6_(complex) STING_p-S172-TBK1_(complex) p-S407_Y641-STAT6_dimer_(complex) STING_STING_(complex) TMEM173 STING_p-S172-TBK1_STAT6_(complex)
BIOCYC_PWY-5695 IMP_dehydrogenase_2_(complex) PNP IMPDH1 IMPDH2 NT5C3B IMP_dehydrogenase_1_(complex) purine_5prime-NT_(complex) 5prime_nucleotidase 5prime-NT_(complex) XDH IMP_DEHYDROGENASE_2_IMPDH_II_IMPD_2 XD_(complex) NT5C2
PID_Nef_mediates_down_modulation_of_cell_surface_receptors_by_recruiting_them_to_clathrin_adapters myristoylated_Nef_Protein_(numerous_variants) AP2S1 ATP6V1H Adaptor_protein_complex_2_(AP-2)_large_adaptins AP2M1 AP-2_Complex_(complex) AP2B1
BIOCYC_PWY-4921 PEPTIDYLARGININE_DEIMINASE PADI1 PADI3 PADI2 PADI4 PADI6
PID_Regulation_of_Insulin_Secretion_by_Fatty_Acids_Bound_to_GPR40__FFAR1_ Phospholipase_C_Beta__G(q)_Complex_(complex) G(q)_alpha__GDP_Complex_(pancreatic_beta_cell)_(complex) Free_fatty_acid_receptor_1_fatty_acid_complex_(complex) G(q)_alpha_GTP__G_beta__G_gamma_Complex_(pancreatic_beta_cell)_(complex) G_beta_G_gamma_Complex_(complex) FFAR1 G(q)_alpha__GTP_Complex_(pancreatic_beta_cell)_(complex) G(q)_GDP__G_beta__G_gamma_Complex_(pancreatic_beta_cell)_(complex)
REACTOME_REACT_169440 TGFB1 TGFBR2_CBL_(complex) Dimeric_TGF-beta_1_(complex) Type_I_receptor_dimer_(complex) TGFBR2 NEDD8_UBC12_(complex) SMAD2 SMAD3 TGF-beta_1_type_II_receptor_Phospho-type_I_receptor_SARA_complex_(complex) ZFYVE9 Large_latent_complex_of_TGF-beta_1_(complex) Phospho-R-SMAD_CO-SMAD_complex_(complex) Phospho-TGF-beta_I_receptor_complex_(complex) NEDD8 SMAD4 Type_II_receptor_complex_(complex) TGF-beta_1_type_II_receptor_Phospho-type_I_receptor_SARA_Phospho-R-SMAD_complex_(complex) Dimeric_TGF-beta1_type_II_receptor_complex_(complex) TGFBR1 TGFB1_TGFBR2_p-5S-T185-TGFBR1_SARA_SMAD2/3_(complex) TGF-beta_1_type_II_receptor_type_I_receptor_complex_(complex) R-SMAD2/3_(family) p-S465/423_467/425-SMAD2/3_(family) UBE2M TGF-beta_1_type_II_receptor_Phospho-type_I_receptor_complex_(complex) CBL Neddylated_TGFBR2_(complex) FKBP1A TGFBR1_FKBP1A_(complex)
REACTOME_REACT_7961 PCNA POLD2 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_(complex) POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 PCNA_homotrimer_(complex) Processive_complex_loaded_on_telomere_Okazaki_fragment_complex_(complex) POLD4 Processive_complex_loaded_on_telomere_ligated_C-strand_Okazaki_fragments_(complex)
PID_Regulation_of_the_Fanconi_anemia_pathway USP1_UAF1_(complex) USP1 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 FANCD2 ZBTB32 FANCI
PID_prc2pathway HDAC1 HDAC2 PRC1/Histone_H3_(complex) PRC2_complex_(complex) Histone_H3 RBBP7 BMI1 RING1 RBBP4 EZH2 PHC1 SUZ12 YY1 EED CBX4
PID_Utilization_of_Ketone_Bodies D-beta-hydroxybutyrate_dehydrogenase_tetramer_(complex) 3-oxoacid_CoA-transferase_homodimer_(complex) ACAT1 OXCT1 acetyl-CoA_acetyltransferase_tetramer_(complex) BDH1
PID_intrinsicpathway PROS1 ZFHX3 Prothrombin fibrin F_XIIa F_IXa SERPING1 prekallikrein_B F_Xa HKa Thrombin/Fibrin_(complex) F_VIIIa F_Xa/F_VIIIa/PF3_(complex) Protein_C/Protein_S_(complex) F_Va KLKB1 Thrombin/Thrombin_receptor_(complex) COL4A6 COL4A5 COL4A4 COL4A3 COL4A2 COL4A1 F12 F10 F11 F2 F5 F8 F9 KNG1 PF3 F_Xa/F_VIIIa/PF3/F_Va_(complex) F2R collagen_IV_(complex) F_XIa PROC
BIOCYC_PWY-5514 UAP1 GNPNAT1 GPI GNPDA2 glucosamine-phosphate_N-acetyltransferase_1 GCK GNPDA1 PGM3 GALE HKDC1 unknown//unknown
PID_Hormone_ligand_binding_receptors LHCGR FSH_receptor_FSH_(complex) LHB Thyrotropin_(complex) FSHB CGA TSHB Gonadotropin_(complex) CGB7 Lutropin_(complex) GnRH_receptor_Gonadotropin_(complex) Follitropin_(complex) FSHR TSHR LH_receptor_LH_(complex) TSH_receptor_TSH_(complex) GnRH_receptor
PID_tsp1pathway GZMA FOS JUN FYN CD36 MAPK14 AP-1_(complex) TSP-1/CD36/FYN_(complex) CASP3
PID_Plasmalogen_biosynthesis AGPS AGPS_FAD_(complex) FAR2 FAR1 GNPAT GNPAT_AGPS_complex_(complex)
REACTOME_REACT_25195 AGE_adducts_Peptide_AGER-1_2_3_(complex) CAPZA1 AGER-1__2__3_(family) CAPZA2 PRKCSH AGE_adducts_Peptide_(complex) AGER_ligands_AGER_(complex) F-actin_capping_protein_alpha_protein_fragment_TRTK-12_(family) AGER ERK_(family) MAPK3 F-actin_capping_protein_fragment_TRTK12_S100B_homodimer_(complex) DDOST S100B_homodimer_(complex) LGALS3 MAPK1 AGER_ligands_AGER_ERK_(complex) S100B
PID_p75NTR_recruits_signalling_complexes NGF mature_NGF_homodimer_p75NTR_(complex) IKBKB Poly-ubiquitinated_TRAF6_(complex) IRAK1_MYD88_(complex) NGFR NGF_ligand_p75NTR_IRAK1_MYD88_(complex) mature_beta-NGF_homodimer_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_MYD88_(complex) IRAK1 PRKCI IKK-beta_homdimer_(complex) TRAF6 NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_IKK-beta_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_aPKCi_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_MYD88_TRAF6_(complex) SQSTM1 NGF_p75NTR_RIP2_(complex) MYD88 MYD88_homodimer_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_polyubiquitinated_TRAF6_p62_(complex) RIPK2
REACTOME_REACT_121255 Overexpressed_FGFR2_homodimers_GP369_(complex) Overexpressed_FGFR2_homodimers_(complex) Activated_overexpressed_FGFR2_dimers_(complex) Overexpressed_FGFR2_(family) FGFR2 Overexpressed_FGFR2_TKIs_(complex)
PID_Formation_and_Maturation_of_mRNA_Transcript GTF2H3 GTF2H2 GTF2H1 ERCC3 MNAT1 GTF2H4 CDK7 CAK_(complex) TFIIH_(complex) CCNH ERCC2
REACTOME_REACT_1661 phospho-insulin_receptor_(complex) activated_insulin_receptor_(complex) SHC_activated_insulin_receptor_(complex) phospho-SHC__activated_insulin_receptor_(complex) Insulin_(complex) INS INSR SHC1
PID_Role_of_Abl_in_Robo_Slit_signaling CAP_Abl_Robo1_Slit2_Glypican-1_(complex) Abl_Robo1_Slit2_Glypican-1_(complex) Glypican-1_HSPG_(complex) ROBO1 CAP Slit2_Glypican-1_(complex) Clasp_Abl_Robo1_Slit2_Glypican-1_(complex) GPC1 Abl_tyrosine_kinases Robo1_Slit2_Glypican-1_(complex) Abl_pRobo1_slit2_Glypican-1_(complex) CLASP SLIT2
PID_Stabilization_of_p53 MDM2 ATM TP53
PID_erbb_network_pathway NRG1 ErbB4/EGFR/neuregulin_1_beta_(complex) ErbB4/ErbB2/HBEGF_(complex) EGFR/EGFR/betacellulin/betacellulin_(complex) EGFR/EGFR/amphiregulin/amphiregulin_(complex) ErbB4/ErbB4/neuregulin_3/neuregulin_3_(complex) EGFR EGFR/ErbB2/TGFA_(complex) ErbB4/ErbB4/neuregulin_1_beta/neuregulin_1_beta_(complex) ErbB4/ErbB2/betacellulin_(complex) EGF TGFA AREG EGFR/ErbB2/amphiregulin_(complex) EGFR/EGFR/epiregulin/epiregulin_(complex) EGFR/EGFR/HBEGF/HBEGF_(complex) EGFR/ErbB2/HBEGF_(complex) HBEGF ErbB2/ErbB3/neuregulin_1_beta_(complex) ErbB4_CYT2/ErbB4_CYT2/neuregulin_1_beta/neuregulin_1_beta_(complex) EGFR/ErbB2/betacellulin_(complex) NRG2 ErbB4/ErbB4/neuregulin_2_beta/neuregulin_2_beta_(complex) NRG4 ERBB2 ERBB3 ErbB2/ErbB3/neuregulin_2_(complex) ERBB4 ErbB4/ErbB4/HBEGF/HBEGF_(complex) EGFR/ErbB3/amphiregulin_(complex) ErbB4/EGFR/neuregulin_4_(complex) ErbB4/ErbB2/epiregulin_(complex) EGFR/EGFR/EGF/EGF_(complex) NRG3 ErbB4_JM-B/ErbB4_JM-B/neuregulin_1_beta/neuregulin_1_beta_(complex) EGFR/ErbB2/epiregulin_(complex) EGFR/ErbB3/TGFA_(complex) HSP90_(dimer)_(complex) ErbB4/ErbB4/betacellulin/betacellulin_(complex) ErbB4/ErbB2/neuregulin_4_(complex) EGFR/ErbB3/EGF_(complex) EGFR/EGFR/TGFA/TGFA_(complex) EREG BTC ErbB4/ErbB2/neuregulin_1_beta_(complex) HSP90AA1 EGFR/ErbB3/epiregulin_(complex)
REACTOME_REACT_850 PFKFB1 phosphoPFKFB1_dimer_(complex)
BIOCYC_PWY-7185 NTPCR CTPS2 CTPS1
BIOCYC_PWY-6430 DPYSL4 DPYSL5 DPYSL2 DPYSL3 DPYD DPYS UPB1 CRMP1
PID_erb_genomic_pathway E2/ERB_(dimer)/Src-1_(complex) E2/ERB_(dimer)/NEDD8/UBC12/UBA3_(complex) SMARCE1 E2/ERB_(dimer)/DAX-1_(complex) ZNF14 SMARCA4 NCOA2 NCOA3 NCOA1 INI1/BRG1/BAF57/ER_beta/GIOT-4_(complex) NR0B1 DDX54 ERB/NR0B2_(complex) E2/ERB_(dimer)/AIB1_(complex) E2/ERB_(dimer)_(complex) E2/ERB_(dimer)/DP97_(complex) NEDD8 SMARCB1 UBA3 UBE2M E2/ERB_(dimer)/TIF2_(complex) ESR2 NR0B2
REACTOME_REACT_20514 Partially_Deadenylated_mRNA_Complex_(complex) PABPC1 EIF4G1 PAIP1 eIF4A_(family) EIF4E EIF4A2 EIF4A1 EIF4A3 EIF4B
PID_G2_M_Checkpoints ATRIP ATR_monomer CHEK1 ATR-interacting_protein_(ATRIP)_(complex)
PID_Proteolytic_cleavage_of_SNARE_complex_proteins Syntaxins BoNT_Light_chain_Type_C1_(complex) UniProt_P18640_Botulinum_neurotoxin_type_C1 Syntaxin_fragment
PID_Homologous_recombination_repair_of_replication_independent_double_strand_breaks ATM
PID_NOSIP_mediated_eNOS_trafficking palmitoylated__myristoylated_eNOS_dimer_(complex) NOSIP NOS3 eNOS_NOSIP_(complex)
PID_Signalling_to_p38_via_RIT_and_RIN RIT/RIN NGF RIT/RIN-GDP_(complex) B-Raf_(Zn2+_cofactor)_(complex) Activated_TrkA_receptor_complex_(complex) NTRK1 BRAF beta-NGF_homodimer_(complex) Active_Trk_receptor_complex_RIT/RIN-GTP_B-RAF_(complex) Active_Trk_receptor_complex_RIT/RIN-GTP_(complex) RIT/RIN-GTP_(complex) Active_TrkA_receptor_complex_RIT/RIN-GDP_(complex)
REACTOME_REACT_25283 holoTF_TFRC_(complex) TF_TFRC_(complex) holoTF_TFRC_dimer_(complex) TFRC_dimer_(complex) holoTF_(complex) TFRC TF TF_TFRC_dimer_(complex)
BIOCYC_TYRFUMCAT-PWY TAT fumarylacetoacetase_(complex) homogentisate_dioxygenase_(complex) maleylacetoacetate_isomerase/glutathione_transferase_zeta_(complex) GSTZ1 FAH HGD tyrosine_transaminase_(complex) 4-hydroxyphenylpyruvate_dioxygenase_(complex) HPD
PID_Metal_ion_SLC_transporters MagT1/2 SLC31A1 SLC11A2 SLC40A1 SLC11A1
PID_Shc_events_in_EGFR_signaling SHC1 EGF_Phospho-EGFR_Phospho-SHC_(complex) EGF_Phospho-EGFR_(Y992__Y1068__Y1086__Y1148__Y1173)_dimer_(complex) GRB2_SOS-Phospho-SHC_EGF_Phospho-EGFR_dimer_(complex) p21_RAS EGFR EGF_Phospho-EGFR_(complex) EGF_Phospho-EGFR-SHC_(complex) p21_RAS_GTP_(complex) GRB2 SOS1 p21_RAS_GDP_(complex) EGF GRB2_SOS1_(complex)
PID_Signal_attenuation Insulin_(complex) GRB10_INSR_(complex) GRB2_phospho-SHC_(complex) GRB10 IRS activated_insulin_receptor_(complex) INS MAPK3 INSR GRB2 SOS1 phospho-insulin_receptor_(complex) phospho-IRS SHC1
REACTOME_REACT_22344 H2BFS MIS18A HIST1H2BB HIST1H4D RBBP7 Centromeric_Chromatin__New_CENPA_Nucleosome_Mis18_HJURP_Complex_(complex) Centromeric_Chromatin_CENPH-I__Mis18_Complex_(complex) ITGB3BP HIST2H2BE HIST1H2AJ HIST1H2AD Histone_H2A_(family) HJURP_Complex_(without_CENPA-H4_tetramer)_(complex) HIST1H2AC HIST1H2AB HJURP NPM1 HJURP_CENPA_Complex_(complex) Centromeric_Chromatin_CENPH-I_Centromeric_Nucleosome_RSF_Complex_(complex) H2AFB1 SMARCA5 Centromeric_Chromatin_CENPH-I_Complex_(complex) HIST1H2BJ RSF1 HIST1H2BK CENPO CENPN CENPK OIP5 CENPI CENPH MIS18BP1 Centromeric_Chromatin_CENPH-I_Mis18_HJURP_CENPA_Complex_(complex) CENPA HIST1H2BD HIST1H2BF RUVBL1 HIST3H2BB HIST1H2BA CASC5 HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H2BH HIST2H2AC CENPQ CENPP HIST2H2AA3 H2AFX H2AFZ RBBP4 CENPA_H4_Tetramer_(complex) RSF_Complex_(complex) MLF1IP Centromeric_Nucleosome_(complex) Mis18_Complex_(complex) Histone_H2B_(family)
BIOCYC_PWY-5963 MOCOS
REACTOME_REACT_424 Cleavage_and_polyadenylation_specificity_factor_(complex) NXF1 Mature_Intronless_Transcript_Derived_mRNA_eIF4E_Complex_(complex) ALYREF Mature_intronless_derived_mRNA_TAP_Aly/Ref_complex_(complex) EIF4E CPSF3 CPSF2 CPSF1
PID_The_proton_buffering_model UCP_dimer_(complex)
BIOCYC_NADSYN-PWY QPRT KYNU KMO AFMID NADSYN1 TDO2 HAAO NMNAT2 NMNAT1
REACTOME_REACT_121399 Sec23p_Sec24p_Complex_(complex) DYNLL1 DYNLL2 AP1M2 AP1M1 OSBPL1A RILP_dimer_(complex) SAR1B CANX Dynactin_(family) ARF1/GDP_(complex) MHC_II_alpha_beta_heterodimer_(complex) ARP-1_(family) TGN-lysosome_vesicle_with_nonameric_complex_(complex) HLA-DPB1 Kinesins_Dynactin_microtubule_(complex) HLA-DRB3 HLA-DRB1 lip10_trimer_(complex) HLA-DRB4 HLA-DRB5 SEC24D SEC24A SEC24C SEC24B peptide_free_MHC_II_HLA-DM_(complex) MHC_II_CLIP_(complex) Clathrin_(complex) RILP RAB7A Dynein_Heavy_chain_(family) Sar1b_GTP_Complex_(complex) Adaptor_protein_complex_2_(AP-2)_large_adaptins_(family) CLTC DNM2 AP2B1 AP2S1 Sec24_(family) MHC_II_lip10_nonamer_(complex) HLA-DQB1 HLA-DQB2 SH3GL2 DYNC2LI1 peptide_loaded_MHC_class_II_(complex) Invariant_chain_trimer_(complex) RAB7_RILP_ORP1L_complex_(complex) SEC13 Dynein_intermediate_chains_(family) Dynamin_(family) AP-1_Clathrin_coated_nonameric_complex_(complex) DYNC1LI2 DYNC2H1 RAB7A_GTP_(complex) AP1G1 HLA_II_beta_chain_(family) Nonameric_complex_in_COPII_vesicle_(complex) CD74 Dynein_light_chain_(family) AP2A2 AP-1_Complex_(complex) DCTN2 DCTN3 DCTN1 DCTN6 DCTN4 DCTN5 SEC23A DHC_dimer_(complex) ARF1 MHC_class_II_alpha/beta_dimer_(complex) AP2M1 DNM1 Adaptor_protein_2_complex_(complex) Sar1b_GTP_Sec23p_Sec24p_Sec13p_Sec31p_Complex_(complex) Nonameric_complex_(complex) HLA_II_alpha_chain_(family) HLA-DPA1 AP-1_mu_(family) MHC_II_alpha/beta_dimer_(complex) DNM3 AP1S1 AP1S2 AP1S3 alpha_beta_dimer_Ii_trimer_calnexin_(complex) SPTBN2 SEC31A lip22_trimer_(complex) HLA-DRA Clathrin-coated_vesicle_(complex) DYNC1I1 DYNC1I2 Dynein_light_intermediate_chain_(family) AP1B1 MHC_II_lip22_nonamer_(complex) Clathrin_coated_MHC_class_II_alpha/beta/Ii_nonamer_(complex) Dynein_complex_(complex) CLTA AP2A1 DYNC1H1 Sar1b_GTP_Sec23p_Sec24p_(complex) MHC_class_II_alpha/beta/Ii_nonamer_(complex) ACTR1A Dynein_Dynactin_microtubule_(complex) ACTR1B AP-1_sigma_(family) HLA-DM/HLA-DO_(complex) Sec13p_Sec31p_Complex_(complex) HLA-DQA1 HLA-DQA2
REACTOME_REACT_11167 3_cytosolic_halocarboxylases_(complex) PCCA Btn-ACACA_2Mn2+_(complex) mitochondrial_holocarboxylases_(complex) PCCB 3-methylcrotonyl-CoA_carboxylase_complex_(complex) 4x(Btn-PC_Mn2+)_(complex) PC biotinylated_propionyl-CoA_carboxylase_dodecamer_(complex) propionyl-CoA_carboxylase_protomer_(complex) ACACA ACACB_2Mn2+_(complex) MCCC2 MCCC1 Btn-ACACB_2Mn2+_(complex)
REACTOME_REACT_25162 IFNA/B_IFNAR2_p-JAK1_STAT2_p-IFNAR1_p-TYK2_p-STAT2_STAT1_(complex) p-STAT2_STAT1_(complex) IFNA/B_IFNAR2_JAK1_STAT2_(complex) IFNAR2 IFNAR1 IFNAR2_p-JAK1_STAT2_(complex) TYK2 IFNA/B_IFNAR2_p-JAK1_STAT2_IFNAR1_TYK2_(complex) STAT2 STAT1 p-STAT1_(family) IFNA/B_IFNAR2_JAK1_STAT2_IFNAR1_TYK2_(complex) STAT2_1_hetero_dimer_(complex) STAT1_alpha/beta_(family) JAK1 IFNAR2c_UBP43_(complex) IFNAR2_JAK1_STAT2_(complex) IFNAR1_TYK2_(complex) p-STAT2_p-STAT1_p-IFNAR1_p-TYK2_(complex) p-STAT2_STAT1_p-IFNAR1_p-TYK2_(complex) USP18 IFNA/B_IFNAR2_p-JAK1_STAT2_p-IFNAR1_p-TYK2_p-STAT2_p-STAT1_(complex) SOCS1 SOCS3 SOCS-1_and_SOCS-3_(family) p-IFNAR1_p-TYK2_SOCS-1/SOCS-3_(complex) p-TYK2_p-IFNAR1_SOCS-1/SOCS-3_IFNA/B_IFNAR2_p-JAK1_STAT2_(complex) IFNA/B_IFNAR2_p-JAK1_STAT2_(complex)
BIOCYC_PWY3DJ-11470 ACER2 SPHK2 SPHK1 ACER1 ASAH1 ASAH2 ASAH2C PTGR1 SGPP2 SGPP1
REACTOME_REACT_13806 Active_N-SMase_Mg2+_(complex) SMPD2
PID_Pyrimidine_metabolism TYMP UPP1_dimer_(complex) UPP1 thymidine_phosphorylase_dimer_(complex)
PID_RAF_activation RAS_RAF_(complex) Activated_RAF1_complex_(complex) p21_RAS p21_RAS_GTP_(complex) RAS_RAF_14-3-3_(complex) p-Raf1(S259_S621)_14-3-3_protein_beta/alpha_(complex) YWHAB RAF1
REACTOME_REACT_12510 palmitoylated__myristoylated_eNOS_dimer_(complex) NOSIP NOS3 eNOS_NOSIP_(complex)
PID_relapathway HDAC3 NF-kappa-B_(complex) NFKBIA I-kappa-B-alpha/RELA/p50_(complex) RELA EP300 p50 p300/CBP/RELA/p50_(complex) CREBBP
PID_Transport_of_Notch_receptor_precursor_to_golgi NOTCH4 NOTCH1 NOTCH2 NOTCH3
PID_Purine_ribonucleoside_monophosphate_biosynthesis phosphoribosyl_pyrophosphate_amidotransferase_tetramer_(complex) ATIC adenylosuccinate_lyase_tetramer_(complex) PAICS_octamer_(complex) PAICS ATASE-(4Fe-4S)-(PRPP-Glutamine)_reactive_complex_(complex) 5-aminoimidazole-4-carboxamide_ribonucleotide_formyltransferase/IMP_cyclohydrolase_dimer_(complex) ADSL PPAT GART PFAS GMPS
BIOCYC_PWY-7181 UPP2 UPP1 CDA cytidine_aminohydrolase_(complex) TYMP TP_(complex) AICDA
PID_Lysine_catabolism alpha-ketoglutarate_dehydrogenase_E1_holoenzyme_(complex) OGDH alpha-keto_acid_dehydrogenase_E3_homodimer_(complex) AADAT lysine-ketoglutarate_reductase_/saccharopine_dehydrogenase_homotetramer_(complex) DLD AASS DLST glutaryl-CoA_dehydrogenase_tetramer_(complex) alpha-ketoglutarate_dehydrogenase_E1_homodimer_(complex) alpha-ketoglutarate_dehydrogenase_complex_(complex) antiquitin_tetramer_(complex) SLC25A21 alpha-ketoglutarate_dehydrogenase_E2_holoenzyme_(complex) AADAT_dimer_(complex) ALDH7A1 alpha-keto_acid_dehydrogenase_E3_holoenzyme_(complex) GCDH
REACTOME_REACT_6190 NUP88 Crm1_Ran_GTPase_GTP_(complex) AAAS Ran_GTPase_GDP_(complex) NUP133 Rev_multimer-bound_HIV-1_mRNA_Crm1_Ran_GTP_NPC_(complex) Rev-bound_HIV-1_mRNA_(complex) Rev_multimer-bound_HIV-1_mRNA_(complex) NUP85 Rev_multimer-bound_HIV-1_mRNA_CRM1_complex_(complex) XPO1 NUP62 SEH1L EMBL_AF033819_EMBL_AF033819 RAN Ran-GTP_(complex) NUP98 NUP43 NUP188 NUP214 NUP210 RANBP2 POM121 NUP107 Nup107_Complex_(complex) NUP160 NUP93 TPR Ran_GTP_(complex) Nup62_Complex_(complex) NUPL1 NUPL2 Rev_multimer-bound_HIV-1_mRNA_Crm1_Ran_GTP_(complex) NUP50 NUP54 RANBP1 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 NUP153 RanBP1_Ran-GTP_CRM1_Rev-bound_mRNA_complex_(complex) UniProt_P04618_rev NUP155 NUP205 RAE1
PID_betacatenin_deg_pathway WNT3A DVL Axin1/APC/GSK3/beta_catenin_(complex) CTNNB1 CK1_epsilon-CK1_delta-CK1_alpha AXIN2 WNT3A/LRP6/FZD5/DVL/Axin1/GSK3_(complex) SKP1 SCF_(complex) WNT3A/LRP6/FZD5/DVL_(complex) Axin2/GSK3_(complex) GSK3 CUL1 Axin1/APC//beta_catenin/GSK3_(complex) Axin1/APC//beta_catenin_(complex) FZD5 LRP6 AXIN1 APC/beta_catenin_(complex) BTRC APC WNT3A/LRP6/FZD5_(complex)
PID_Formation_of_HIV_1_elongation_complex_in_the_absence_of_HIV_1_Tat HIV-1_early_elongation_complex_with_hyperphosphorylated_Pol_II_CTD_(complex) NELFB P-TEFb_complex_(complex) ERCC2 ERCC3 CTDP1 POLR2B TCEB3 CCNT1 CDK7_(complex) Elongin_B_C_complex_(complex) NELFE CCNT2 RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) SSRP1 phospho-Spt5 TCEB2 FACT_complex_(complex) TCEA1 Elongin_Complex_(complex) SUPT16H NELFA ELL GTF2H3 GTF2H2 GTF2H1 TCEB1 GTF2H4 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C CDK9 POLR2L MNAT1 HIV-1_elongation_complex_(complex) POLR2I POLR2H POLR2K POLR2J GTF2F1 NELFCD GTF2F2 NELF_complex_(complex) TFIIH_(complex) SUPT4H1 DSIF_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex) CCNH
PID_Phenylalanine_and_tyrosine_catabolism TAT fumarylacetoacetate_hydrolase_dimer_(complex) pterin-4-alpha-carbinolamine_dehydratase_homotetramer_(complex) phenylalanine_hydroxylase_holoenzyme_tetramer_(complex) 4-hydroxyphenylpyruvate_dioxygenase_holoenzyme_dimer_(complex) PCBD1 GSTZ1 TAT_dimer_(complex) maleylacetoacetic_acid_isomerase_dimer_(complex) dihydropteridine_reductase_homodimer_(complex) FAH QDPR PAH HGD homogentisic_acid_oxidase_hexamer_(complex) HPD
PID_Dopamine_Neurotransmitter_Release_Cycle STX1A SNAP25 VAMP2 Dopamine_loaded_synaptic_vesicle_(complex) SYT1 Rab3-RIM_complex_(complex) STXBP1 Docked_dopamine_loaded_synaptic_vesicle_(complex) CPLX1 RAB3A SLC18A2 RIMS1
PID_RNA_Polymerase_III_Transcription_Initiation_From_Type_3_Promoter RNA_Polymerase_III_Holoenzyme_(complex) SNAPc_(complex) POLR3F POLR3D POLR3E POLR3B POLR3A POLR2E POLR3H ZNF143 TFIIIB-Type_3_Promoter_Selective_Complex_(complex) POLR2H SNAPc_Oct-1_Staf_Type_3_Promoter_Complex_(complex) BDP1 LZTS1 RNA_Polymerase_III_TFIIIB_SNAPc_Type_3_Open_Promoter_Complex_(complex) SNAPC2 SNAPC1 POLR2F SNAPC5 SNAPC4 BRF2 POLR2L RNA_Polymerase_III_TFIIIB_SNAPc_Type_3_Promoter_Complex_(complex) POLR2K SNAPC3 TBP TFIIIB_SNAPc_Oct-1_Staf_Type_3_Promoter_Complex_(complex) POU2F1
PID_Post_chaperonin_tubulin_folding_pathway Cofactor_D_GTP_beta_tubulin_(complex) GTP_beta-tubulin_folding_intermediate_(complex) TBCE TBCD Cofactor_E_GTP-alpha_tubulin_folding_(complex) TBCB TBCA cofactor_A_GTP_beta-tubulin_folding_intermediate_(complex) beta-tubulin_folding_intermediate Cofactor_B_GTP-alpha_tubulin_(complex) GTP-alpha-tubulin_folding_intermediate_(complex) beta-tubulin_GTP_Cofactor_D_alpha-tubulin_GTP_Cofactor_E___Cofactor_C_(complex) TBCC beta_tubulin_GTP__Cofactor_D_alpha_tubulin_GTP_Cofactor_E_(complex)
BIOCYC_PWY-6609 PNP HGPRTase_(complex) HPRT1 ADAT3 ADA
PID_Role_of_DCC_in_regulating_apoptosis DCC_DIP13alpha_(complex) Unc5B_with_death_domain_DAPK_(complex) UNC5A CASP3 UNC5B MAGED1 DCC_DIP13alpha_Caspase-9_(complex) DCC CASP9 APPL1 UNC5A_NRAGE_(complex) Cleaved_Caspase-9_(complex) active_caspase-3_(complex) DAPK1
PID_NGF_processing NGF mature_beta-NGF_homodimer_(complex) Subtilisin/kexin_convertase_(Calcium_dependant)_(complex) pro-beta-NGF_homodimer_(complex)
REACTOME_REACT_683 Emi1_Cdc20/Cdh1_complex_(complex) phospho-Emi1(Ser_145__Ser_149)_Cdc20/Cdh1_complexes_(complex) FZR1 CDC20 FBXO5 Phospho-Emi1(Ser_182)_Cdc20/Cdh1_complexes_(complex) Cdc20/Cdh1_(family)
REACTOME_REACT_6934 apolipoprotein(a)_LDL_complex_(complex) CETP LDLR low-density_lipoprotein_complex_(complex) APOB LDL_LDLR_complex_(complex) CETP_triacylglycerol_complex_(complex) LPA
PID_CREB_phosphorylation_through_the_activation_of_CaMKK Calmodulin_CaMK_IV_(complex) CALM3 CAMK4 CREB1 CAMKK1 Active_Calmodulin_(complex)
PID_Assembly_of_the_RAD51_ssDNA_nucleoprotein_complex RPA_heterotrimer_(complex) RAD51_RAD52_DNA_double_strand_break_end_complex_(complex) RPA1 RPA3 RPA2 RAD52 RAD51 RAD51_resected_ends_of_DNA_double-strand_break_(complex) RAD51_RPA_complex_(complex)
PID_Toll_Like_Receptor_4__TLR4__Cascade LBP JALI_7601 TLR4_MD2_complex_(complex) RP105_MD1_(complex) CD14 LBP_complexed_with_bacterial_LPS_(complex) TLR4 LY96 CD180 Chlamydial_HSP60_bound_to_TLR4_(complex) LY86
REACTOME_REACT_25042 YWHAZ DCP2 DIS3 KSRP_mRNA_Complex_(complex) KSRP_mRNA_Degradation_Complex_(complex) Exosome_Ring_Hexamer_(complex) KHSRP EXOSC8 EXOSC9 Phosphorylated_KSRP_(Ser193)_14-3-3zeta_Complex_(complex) Exosome_Complex_(complex) PARN EXOSC2 EXOSC3 EXOSC1 EXOSC6 EXOSC7 EXOSC4 EXOSC5
PID_ABH2_mediated_Reversal_of_Alkylation_Damage ALKBH2
PID_Down_stream_signal_transduction PDGFRB PI3K_(complex) PDGF_Phospho-PDGFR_receptor_dimer_Nck_(complex) PLCG1 PDGF_Phospho-PDGF_receptor_dimer_Grb2_Sos1_(complex) PDGF_Phospho-PDGF_receptor_dimer_phospho-Src_(complex) PDGF_Phospho-PDGF_receptor_dimer_Grb7_(complex) GRB2_SOS1_(complex) PI3K-catalytic_subunit PDGF_B_homodimer_(complex) Phospho-beta_receptor_homodimer_GAP_(complex) NCK PDGF_Phospho-PDGF_receptor_dimer_Crk_p130Cas_C3G_(complex) SRC PDGFB PDGF_Phospho-PDGF_receptor_dimer_Src_(complex) PI3K-regulatory_subunit PDGF_Phospho-PDGF_receptor_dimer_PI3K_(complex) Phospho-beta_receptor_homodimer_(complex) PDGF_phospho-PDGF_receptor_dimer_STAT_(complex) Phospho_PDGF_beta_receptor__PDGF_chain_B_homodimer_(complex) BCAR1 RASA1 PDGF_Phospho-PDGF_receptor_dimer_SHP2_(complex) SOS1 PDGF_Phospho-PDGF_receptor_dimer_(complex) p21_RAS PDGF_Phospho-PDGF_receptor_dimer_Crk_(complex) p21_RAS_GTP_(complex) GRB2 GRB7 PDGF_Phospho-PDGF_receptor_dimer_PLC-gamma_(complex) PTPN11 RAPGEF1
REACTOME_REACT_21303 NTN3 CDH15 MYF5 MYF6 myogenic_regulatory_factors_(MRFs)_(family) CDO_BOC_Neogenin_Netrin-3_(complex) CTNNB1 MAPK11 MAPK12 Cadherin_Catenin_(complex) ABL1 CDO_BOC_Trans-cadherin_homodimer_catenin_(complex) MYOG Cadherin-catenin_CDO_BOC_Bnip2_CDC42-GTP_(complex) p38_MAPK_alpha/beta/gamma_(family) BOC ABL1_JLP_CDO_complex_(complex) MEF2B Promyogenic_cadherins_(family) MEF2A alpha/beta_catenin_(family) pp38_alpha/beta/gamma_ABL1_JLP_CDO_complex_(complex) phospho-MEF2_proteins_(family) NEO1 BNIP2 Phospho-p38_MAPK_alpha/beta/gamma_(family) CDH2 CDH4 TCF4 TCF3 SPAG9 Trans-cadherin_homodimers_(complex) TCF12 Myod_phospho-E_heterodimers_(complex) phospho-E_proteins_(family) CDO_BOC_(complex) Cadherin-catenin_JLP_CDO_BOC_Bnip2-Cdc42_(complex) CTNNA1 CTNNA2 MYOD1 MAPK14 phospho-p38_alpha/beta/gamma_MAPK_(family) MyoD_phospho-E_phospho_MEF2_(complex) MEF2_proteins_(family) MEF2C CDC42-GTP_(complex) CDON Cadherin-catenin_CDO_BOC_Bnip2_(complex) MEF2D Netrin-3_Neogenin_(complex) p38_alpha/beta/gamma_ABL1_JLP_CDO_complex_(complex) phospho_p38_phospho_MEF2_(complex) CDC42
REACTOME_REACT_207 Orc2_associated_with_MCM8_(complex) RPS27A UBIQ_HUMAN_(family) CDT1_CDC6_ORC_origin_complex_(complex) CDT1 CDC6 CDC6_ORC_origin_complex_(complex) pre-replicative_complex_(Orc1-minus)_(complex) ORC6 ORC4 ORC5 ORC2 ORC3 ORC1 MCM7 MCM5 MCM4 MCM3 MCM2 Mcm2-7_complex_(complex) pre-replicative_complex_(complex) ubiquitin_(family) UBA52 ORC_origin_(complex) ubiquitinated_Orc1_(complex)
PID_Class_C_3__Metabotropic_glutamate_pheromone_receptors_ Umami_taste_receptor_(complex) TAS1R3 Metabotropic_glutamate_receptors_L-Glutamate_(complex) Sweet_taste_receptor_sweet_taste_stimuli_(complex) CASR_Calcium_(complex) Metabotropic_glutamate_receptors Sweet_taste_receptor_(complex) Umami_taste_receptor_L-glutamate_(complex) GPRC6A_receptor_GPRC6A_ligands_(complex) GPRC6A GABAB_receptor_GABA_(complex) CASR TAS1R1 GABBR1 GABAB_receptor_(complex) TAS1R2 GABBR2
REACTOME_REACT_378 RAD23B ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 pre-incision_complex_in_GG-NER_(complex) XPC_HR23B_damaged_DNA_complex_(complex) TFIIH_(complex) RPA_heterotrimer_(complex) ERCC1_XPF_complex_(complex) XPC DDB2 DDB1 XPA GTF2H3 GTF2H2 GTF2H1 GTF2H4 XPC_HR23B_complex_(complex) MNAT1 pre-incision_complex_with_open_DNA_bubble_(complex) RPA1 RPA3 RPA2 incision_complex_for_GG-NER_(complex) CDK7 CAK_(complex) CCNH
REACTOME_REACT_21330 TXN GLRX
PID_Recognition_and_association_of_DNA_glycosylase_with_site_containing_an_affected_pyrimidine SMUG1 hSMUG1glycosylase_uracil_complex_(complex) UNG2_glycosylase_uracil_complex_(complex) hNTH1_glycosylase_thymine_glycol_complex_(complex) MBD4_glycosylase_thymine_complex_(complex) MBD4_glycosylase_uracil_complex_(complex) TDG hNTH1_glycosylase__foramidopyrimidine_complex_(complex) hNTH1_glycosylase_cytosine_glycol_complex_(complex) MBD4 TDG_glycosylase_uracil_complex_(complex) NTHL1 CCNO TDG_glycosylase_ethenocytosine_complex_(complex) hNTH1_glycosylase_dihydrouracil_complex_(complex) TDG_glycosylase_thymine_complex_(complex) UNG2_glycosylase_5-hydroxyuracil_complex_(complex)
BIOCYC_PWY-7209 UPP2 DPYSL4 DPYSL5 DPYSL2 CDA DPYD UPP1 cytidine_aminohydrolase_(complex) DPYS UPB1 CRMP1 AICDA DPYSL3
PID_kitpathway MAP4K1 TEC CRKL HRAS/SPRED1_(complex) PI3K_(complex) HRAS PTPN6 SPRED1 SPRED2 GAB1 FOXO3 EPO BAD CBL/CRKL/GRB2_(complex) STAT5A_(dimer)_(complex) MITF KIT HRAS/SPRED2_(complex) MAP2K2 SCF/KIT_(complex) STAT1 PKC PIK3CA SHC/GRB2/SOS-1_(complex) SCF/KIT/EPO/EPOR_(complex) RPS6KB1 VAV1 GRB2/SOCS1/VAV1_(complex) MAPK3 STAP1 GRAP2 JAK2 PIK3R1 LYN STAT3 SHC1 PIK3C2B STAT3_(dimer)-active_(complex) FER SH2B3 SNAI2 SHC/GRAP2_(complex) KITLG MAPK8 RAF1 EPOR MATK SOCS1 SOS1 AKT1 SH2B2 GRB10 PTPN11 MAP2K1 CBL GSK3B CBL/CRKL_(complex) PTEN STAT5A GRB2 STAT1_(dimer)_(complex) PTPRO LYN/TEC/p62DOK_(complex) DOK1 STAP1/STAT5A_(dimer)_(complex)
REACTOME_REACT_120863 Activated_FGFR2c_mutants_with_enhanced_ligand-binding_(complex) FGFR2_mutant_dimers_with_enhanced_kinase_activity_(complex) FGFR2c_mutant_dimers_with_enhanced_ligand-binding_(complex) FGFR2_ligand-independent_mutants_(family) Activated_FGFR2_mutants_with_enhanced_kinase_activity_(complex) FGFR2b_mutants_with_enhanced_ligand_binding_(family) phosphorylated_FGFR2b_mutant_dimers_with_enhanced_ligand_binding_(complex) FGFR2_point_mutant_dimers_TKIs_(complex) FGFR2b_mutant-binding_FGFs_FP-1039_(complex) FGFR2b_mutant_dimers_with_enhanced_ligand-binding_bound_to_FGFs_(complex) FGFR2_mutants_with_enhanced_kinase_activity_(family) FGFR2b_mutant_dimers_with_enhanced_ligand-binding_(complex) phosphorylated_FGFR2c_mutant_dimers_with_enhanced_ligand-binding_(complex) FGFR2_ligand-independent_mutant_dimers_(complex) Activated_FGFR2_ligand-independent_mutants_(complex) FGFR2c_mutants_with_enhanced_ligand_binding_(family) FGFR2c_mutant_dimers_with_enhanced_ligand-binding_bound_to_FGFs_(complex) FGFR2 Activated_FGFR2b_mutants_with_enhanced_ligand_binding_(complex)
PID_NF_kB_is_activated_and_signals_survival NF-kB_complex_(complex) NGF Phospho-IKK-beta_homdimer_(complex) mature_NGF_homodimer_p75NTR_(complex) IKK-beta_homdimer_(complex) TRAF6 NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_Phospho-IKK-beta_(complex) NGF_ligand_p75NTR_Phospho-IRAK1_TRAF6_p62_IKK-beta_(complex) NFKBIA mature_beta-NGF_homodimer_(complex) IKBKB UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 SQSTM1 NGFR NFKB1 RELA IRAK1 Ubiquitinated_phospho-IkB_(complex)
PID_APC_C_Cdc20_mediated_degradation_of_Securin phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) PSMD9 PSMD8 PSMD5 PSMD11 PSMD7 PSMD6 PSMD1 PSMD3 PSMD2 PSMD12 UBE2D1 PSMF1 CDC16 ANAPC11 ANAPC10 PSMA2 PSMA3 PSMA1 PSMA6 PSMA7 PSMA4 PSMA5 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 UBE2E1 multiubiquitinated_Securin_in_complex_with_CDC20_phospho-APC/C_(complex) PSME2 PSME3 PSME1 PSMD14 Cdc20_Phospho-APC/C_(complex) PTTG1 ANAPC1 ANAPC2 ANAPC5 ANAPC4 ANAPC7 PSMD4 CDC27 CDC26 UBE2C CDC23 PSMD10 PSMD13 CDC20 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 Cdc20_phosph-APC/C_Securin_complex_(complex) PSMB9 PSMB8 PSMB7 PSMB6 PSMB5 PSMB4 PSMB3 PSMB2 PSMB1
REACTOME_REACT_121206 KS_core_proteins_(family) OMD ACAN OGN FMOD PRELP Keratan_sulfate_proteoglycan_(family) LUM KERA
REACTOME_REACT_15381 SRC ITGB3 Integrin_alpha2bbeta3_(complex) APBB1IP ITGA2B Talin_RIAM_complex_(complex) RAP1B FADK1_bound_p130Cas_complex_(complex) RIAM_bound_to_Rap1-GTP_(complex) Integrin_alphaIIb_beta3_Active_(p-Y419)-SRC_(complex) PTK2 Phosphorylated_p130Cas_in_complex_with_FADK1_(complex) RAP1A Talin_RIAM_complex_ECM_ligands_2X(Integrin_alphaIIb_beta3_Active_(p-Y419)-SRC)_(complex) p(Y397_407_576_577_861_925)-PTK2_(complex) CRK RAP1/GTP_(complex) TLN1 BCAR1 RAP1_(family) Talin_RIAM_complex_ECM_ligands__Integrin_alphaIIb_beta3_Active_(p-Y419)-SRC_p(Y397_407_576_577_861_925)-FADK1_(complex)
BIOCYC_PWY-6898 TPK1
PID_Cation_coupled_Chloride_cotransporters NKCC_cotransporters KCC_cotransporters SLC12A3
PID_Cooperation_of_Prefoldin_and_TriC_CCT__in_actin_and_tubulin_folding CCT8 CCT2 CCT3 CCT/TriC(ADP)_(complex) CCT7 CCT4 CCT5 TCP1 CCT6A
PID_Sodium_coupled_sulphate__di__and_tri_carboxylate_transporters SLC13A1 SLC13A2 SLC13A3 SLC13A4 SLC13A5
REACTOME_REACT_790 PDPK1 AKT2 PIP3_PDK1_complex_(complex) PIP3_AKT2_complex_(complex) PIP3_Phosphorylated_PKB_complex_(complex)
PID_reelinpathway VLDLR CRKL DAB1/LIS1_(complex) LRPAP1 ARHGEF2 ITGA3 MAP1B RAP1A MAP2K7 RAPGEF1 RELN/LRP8_(complex) DAB1 RELN/LRP8/DAB1_(complex) GRIN2B/RELN/LRP8/DAB1/Fyn_(complex) PIK3CA FYN RELN/VLDLR/DAB1/P13K_(complex) RELN/VLDLR/DAB1_(complex) CDK5R1 RELN PIK3R1 DAB1/CRKL/C3G_(complex) DAB1/NCK2_(complex) MAPK8 ITGB1 GRIN2A/RELN/LRP8/DAB1/Fyn_(complex) RELN/LRP8/DAB1/Fyn/MAPK8IP1/MKK7/MAP3K11/JNK1_(complex) RELN/LRP8/DAB1/Fyn_(complex) CDK5R1/CDK5_(complex) LRPAP1/LRP8_(complex) RELN/LRP8/Fyn_(complex) PAFAH1B1 MAPK8IP1 NCK2 DAB1/alpha3/beta1_Integrin_(complex) LRP8 CBL GSK3B GRIN2B MAP3K11 GRIN2A CDK5 MAPT RELN/VLDLR/DAB1/Fyn_(complex) RELN/VLDLR_(complex)
REACTOME_REACT_12541 NOS3 eNOS_Caveolin-1_NOSTRIN_Dynamin-2_(complex) eNOS_Caveolin-1_NOSTRIN_complex_(complex) eNOS_Caveolin-1_NOSTRIN_dynamin-2_N-WASP_(complex) NOSTRIN_homotrimer_(complex) WASL DNM2 palmitoylated__myristoylated_eNOS_dimer_(complex) NOSTRIN eNOS_Caveolin-1_(complex) CAV1
BIOCYC_PWY-6334 COMT
PID_Deposition_of_New_CENPA_containing_Nucleosomes_at_the_Centromere MIS18A HIST1H4E Centromeric_Chromatin__New_CENPA_Nucleosome_Mis18_HJURP_Complex_(complex) Centromeric_Chromatin_CENPH-I__Mis18_Complex_(complex) ITGB3BP HJURP_Complex_(without_CENPA-H4_tetramer)_(complex) HJURP RSF_Complex_(complex) HJURP_CENPA_Complex_(complex) Centromeric_Chromatin_CENPH-I_Centromeric_Nucleosome_RSF_Complex_(complex) SMARCA5 Centromeric_Chromatin_CENPH-I_Complex_(complex) CENPO CENPN CENPK OIP5 CENPI CENPH MIS18BP1 Centromeric_Chromatin_CENPH-I_Mis18_HJURP_CENPA_Complex_(complex) CENPA RSF1 CASC5 RUVBL1 NPM1 CENPQ CENPP RBBP7 RBBP4 CENPA_H4_Tetramer_(complex) MLF1IP Centromeric_Nucleosome_(complex) Mis18_Complex_(complex)
PID_at1rpathway CRKL c-JUN/ATF-2_(complex) HRAS EGFR RAC1 MAP2K2 MAP2K1 MAP2K4 AGT RAF1 PKC SHC/GRB2/SOS-1_(complex) MAP3K1 JUN MAPK3 CaM/Ca_++_(complex) ELK1 MAPK8 SRC SHC1 FOS BCAR1 GNAQ SOS1 Angiotensin_II/AT1-R/G-alpha-q_(complex) PYK2/SRC/P130cas/CRKL_(complex) PLCG1 PTK2B GRB2 CaM PYK2/SRC_(complex) MAPK1 AGTR1 PAK1 ATF2
REACTOME_REACT_15398 POMC
PID_Eukaryotic_Translation_Initiation RPL37A RPL23A RPL6 RPL7 RPL27A RPL5 RPL18A RPL3 RPL3L EMBL_V00589 60S_ribosomal_complex_(complex) RPL41 RPL7A RPL29 RPL28 RPL24 RPL27 RPL26 RPL21 RPL23 RPL22 RPL13A RPLP2 RPL9P7 RPL8 RPL4 RPL36A RPLP0 RPLP1 RPL35A RPL14 RPL15 RPL17 RPL10 RPL11 RPL12 RPL13 RPL18 RPL19 EMBL_J01866 RPL26L1 RPL38 RPL39 RPL36 RPL37 RPL34 RPL35 RPL32 RPL30 RPL31 UBA52 RPL10A EMBL_M11167
PID_Fructose_catabolism fructose-bisphosphate_aldolase_B_tetramer_(complex) ALDOB
BIOCYC_PWY-6132 LSS
PID_Telomere_Extension_By_Telomerase Telomerase_RNP_(complex) TERT RUVBL1 Telomerase_Holoenzyme_Telomeric_RNP_End_with_Two_Additional_Single_Stranded_Telomere_Repeats_(complex) RUVBL2 Telomerase_RNP_Bound_and_base-paired_to_the_Telomeric_Chromosome_End_(complex) Telomerase_RNP_Bound_to_the_Telomeric_Chromosome_End_(complex) NHP2 WRAP53 DKC1 Telomerase_RNP_Telomeric_Chromosome_End_with_an_Additional_single_Stranded_Telomere_repeat_(complex) EMBL_U86046_TERC Telomerase_Holoenzyme_Base-paired_to_the_Telomeric_Chromosome_End_with_an_Additional_single_Stranded_Telomere_repeat_(complex)
PID_Lysosome_Vesicle_Biogenesis ARF1/GTP_(complex) CLTC AP1G1 ARF1 AP-1_sigma DNM2 Clathrin_Triskelion_(complex) Lysosome_Destined_Cargo_AP-1_Beta-arrestin_Vamp_Clathrin_Triskelion_Dynamin_Endophilin_Complex_(complex) ARF1/GDP_(complex) CLTA AP-1_Complex_(complex) ARRB1 Lysosome_Destined_Cargo_AP-1_beta-Arrestin-1_Vamp_Complex_(complex) AP1B1 AP-1_mu Lysosome_Destined_Cargo_AP-1_Arf1-GTP_beta-Arrestin-1_Vamp_Complex_(complex) SH3GL2
PID_raccpathway SOC/RACC_channel BDKRB2 ADCY1 G-alpha-s/GTP_(complex) CNG/HCN_channel GNB1 G-protein_Receptor SGC AKT1 CaM/Ca_++_(complex) NOS3 PKG CaM HSP90AA1 KNG1 G-alpha-S Ligand/GPCR(+)/g-beta/g-gamma_(complex) bradykinin/Bradykinin_receptor_B2_(complex) GNGT1 Ligand
REACTOME_REACT_12606 MAP2K2 MAPK1 phospho-ERK-2_dimer_(complex) MEK2_ERK-2_(complex) phospho-ERK-2_MEK2_(complex)
REACTOME_REACT_2159 Cap_Binding_Complex_(CBC)_(complex) NCBP1 NCBP2 snRNP_Sm_core_complex_(complex) SF3B5 SF3B4 SF3B1 SF3B3 SF3B2 PRPF8 POLR2L TXNL4A U12_snRNP_(complex) ATAC_C_Complex_with_lariat_containing_5prime-end_cleaved_mRNA_(complex) U4_ATAC_U5_U6_ATAC_Complex_(complex) PRPF6 SNRNP200 SRSF7 SRSF6 SRSF1 RNA_Polymerase_II_(unphosphorylated)_TFIIF_complex_(complex) SRSF2 SNRPF SNRPD3 SNRPG EFTUD2 U5_snRNP_(complex) post_exon_ligation_complex_(complex) EMBL_X04293_U5_snRNA ATAC_A_Complex_(complex) SNRPE NHP2L1 U6_ATAC_snRNP_(complex) RNA_Polymerase_II_holoenzyme_complex_(unphosphorylated)_(complex) U4_ATAC_snRNP_U6_ATAC_snRNP_(complex) LSM2 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B SNRPB ATAC_B_Complex_(complex) POLR2I POLR2H POLR2K POLR2J DDX23 SNRNP40 Splicing_Factor_3B_(complex) GTF2F1 SNRPD2 SNRPD1 GTF2F2 SF3B14 U4_ATAC_snRNP_(complex) ATAC_C_Complex_(complex) capped__methylated_pre-mRNA_CBC_Complex_(complex) U11_snRNP_(complex)
PID_Nef_Mediated_CD4_Down_regulation Arf1_Nef_endosomal_CD4_(complex) CD4 AP2S1 CD4_Lck_Complex_(complex) ARF1 ATP6V1H Adaptor_protein_complex_2_(AP-2)_large_adaptins AP2M1 CD4_Nef_Complex_(complex) LCK AP-2_Complex_(complex) myristoylated_Nef_Protein_(numerous_variants) Internalized_CD4_Nef_Clathrin-Coated_Pit_Adapter_Protein_v-ATPase_(complex) AP2B1 CD4_Nef_AP-2_Complex_v-ATPase_Complex_(complex)
REACTOME_REACT_12435 AP2S1 NGF Activated_TrkA_receptor_complex_Clathrin-coated_vesicle_(complex) Clathrin-coated_vesicle_(complex) Activated_TrkA_receptor_complex_Clathrin-coated_vesicle_dynein_dynactin_complex_(complex) Activated_TrkA_receptor_complex_(complex) NTRK1 AP2M1 CLTA Clathrin_(complex) AP2A1 Activated_TrkA_receptor_complex_Clathrin-coated_vesicle_Endophilin_(complex) AP2A2 Adaptor_protein_complex_2_(AP-2)_large_adaptins_(family) Adaptor_protein_2_complex_(complex) beta-NGF_homodimer_(complex) AP2B1 SH3GL2
REACTOME_REACT_25354 K63-linked_poly-Ub-p-3S_3T-IRAK1_TRAF6_(complex) p-Pellino-1_2_(3)_(family) PELI1 TRAF6 PELI3 IKKA_IKKB_NEMO_(complex) TRAF6_hp-IRAK1_(complex) CHUK IKBKB IKBKG TRAF6_K63-linked_polyUb_p-IRAK1_IKK_complex_(complex) TRAF6_hp-IRAK1_Pellino_(complex) p-Pellino_hp-IRAK1_TRAF6_(complex) IRAK1
PID_alk2pathway BMP7 AMH ACVR1 BMP7/BMPR2/ALK2_(dimer)_(complex) SMAD1-5-8 SMAD4/SMAD1-5-8_(dimer)_(complex) AMHR2 SMAD4 BMPR2 FKBP1A SMAD1-5-8-active MIS/MISR2/ALK2_(dimer)_(complex)
PID_FMO_oxidizes_nucleophiles FMO2 FMO3 FMO1 FMO2_(FAD__Mg2+_cofactors)_(complex) FMO1_(FAD_cofactor)_(complex) FMO3_(FAD_cofactor)_(complex)
PID_Mitochondrial_tRNA_aminoacylation SARS2 FARS2 EARS2 KARS DARS2_dimer_(complex) GARS_dimer_(complex) CARS2 DARS2 PPA2 LARS2 IARS2 PARS2 WARS2 MARS2 VARS2 AARS2 TARS2 YARS2_dimer_(complex) NARS2 YARS2 QARS GARS PPA2_dimer_(complex) SARS2_dimer_(complex) KARS_dimer_(complex) HARS2 RARS2
PID_mitochondrial_fatty_acid_beta_oxidation_of_unsaturated_fatty_acids LCAD_acyl-CoA_dehydrogenase_homotetramer_(complex) 3_2-trans-enoyl-CoA_isomerase_Homodimer_(complex) 2_4-dienoyl-CoA_reductase__mitochondrial_precursor_(EC_1.3.1.34)_(2_4-_dienoyl-CoA_reductase_[NADPH])_(4-enoyl-CoA_reductase_[NADPH])_Homotetramer_(complex) HADHA MCAD_acyl-CoA_dehydrogenase_homotetramer_(complex) HADHB ECI1 Trifunctional_Protein_(complex) DECR1 ACADL ACADM
REACTOME_REACT_1213 caspase-3-cleaved_DFF45_(117_224)_DFF40_complex_(complex) HMGB2 HMGB1 HMGB1/HMGB2-_bound_chromatin_(complex) Histone_H1_(family) Histone_H1_bound_chromatin_DNA_(complex) DFF45_DFF40_complex_(complex) DFF_associated_with_the_importin-alpha_importin-beta_complex_(complex) DFF40_homodimer_(complex) DFF40_associated_with_chromatin_(complex) importin-alpha_importin-beta_(complex) H1F0 Caspase_cleaved_DFF45_(117)_(complex) KPNB1 DFFA DFFB HIST1H1D HIST1H1E active_caspase-3_(complex) HIST1H1A HIST1H1B HIST1H1C DFF_cleaved_DNA_(complex) HMGB1/HMGB2_(family) CASP3 importin-alpha_importin-beta_complex_(complex) KPNA1
PID_mTORC1_mediated_signalling RPTOR RHEB Activated_mTORC1_(complex) MTOR MLST8 Rheb_GTP_(complex)
PID_vegf_vegfr_pathway VEGFR2_(dimer)/VEGFA189_(dimer)_(complex) VEGFR2/3_(dimer)/VEGFC_(dimer)_(complex) VEGFR1_(dimer)/VEGFA189_(dimer)_(complex) VEGFR2/3_(dimer)/VEGFC_(dimer)/NRP2_(complex) FLT4 VEGFR2_(dimer)/VEGFA_(dimer)_(complex) FLT1 PGF VEGFR2_(dimer)/VEGFA_(dimer)/NRP1_(complex) VEGFR2_(dimer)/VEGFA165B_(dimer)_(complex) VEGFR2_(dimer)/VEGFA145_(dimer)_(complex) VEGFA145_(dimer)/NRP2_(complex) VEGFR1_(dimer)/VEGFB186_(dimer)_(complex) VEGFR2_(dimer)/VEGFA_(dimer)/NRP2_(complex) VEGFR2/3_(dimer)/VEGFA145_(dimer)_(complex) VEGFR1/2_(dimer)/VEGFA/PLGF1_(complex) VEGFR3_(dimer)/VEGFC_(dimer)_(complex) VEGFR1_(dimer)/VEGFA_(dimer)/NRP2_(complex) VEGFR1/2_(dimer)/PLGF1_(dimer)_(complex) KDR FIGF VEGFR3_(dimer)/VEGFD_(dimer)_(complex) VEGFR2/3_(dimer)/VEGFA121_(dimer)_(complex) VEGFR2/3_(dimer)/VEGFA_(dimer)/NRP2_(complex) VEGFR1_(dimer)/PLGF2_(dimer)_(complex) VEGFR1_(dimer)/PLGF1_(dimer)_(complex) VEGFR2/3_(dimer)/VEGFA189_(dimer)_(complex) VEGFA VEGFC VEGFB VEGFR1/2_(dimer)/VEGFA_(dimer)_(complex) NRP1 NRP2 VEGFR2_(dimer)/VEGFA121_(dimer)_(complex) VEGFR2_(dimer)/VEGFD_(dimer)_(complex) VEGFR1_(dimer)/VEGFB167_(dimer)_(complex) VEGFR1_(dimer)/VEGFA_(dimer)_(complex) VEGFR3_(dimer)/VEGFC_(dimer)/NRP2_(complex) VEGFR2/3_(dimer)/VEGFA_(dimer)_(complex) VEGFR1_(dimer)/VEGFA_(dimer)/NRP1_(complex) VEGFR2_(dimer)/VEGFC_(dimer)_(complex) VEGFR1_(dimer)/VEGFA206_(dimer)_(complex) VEGFR2/3_(dimer)/VEGFD_(dimer)_(complex)
PID_Binding_and_entry_of_HIV_virion CCR5/CXCR4_CD4_Env_gp120_(second_conformation_change)_complex_(complex) Virion_with_fusogenically_activated_gp41_(complex) p51_subunit_of_RT Env_gp41_protein gp120_homotrimer_with_exposed_coreceptor_binding_sites_(complex) Reverse_Transcriptase_heterodimer_(complex) Rev CD4 gp120_homotrimer_(complex) Env_oligomer_with_gp41(inserted)/gp120(released)_(complex) Env_gp41_with_heptad_repeats_(HR)_1_and_2_in_hairpin_fold CD4_Env_gp120/gp41_hairpin_complex_CCR5/CXCR4_(complex) Vpr_protein Env_gp120_protein_after_second_conformation_change EMBL_AF033819_EMBL_AF033819 gp120_homotrimer_after_second_conformation_change_(complex) Virion_with_gp41_exposed_(complex) CD4_Env_gp120_(second_conformation_change)_complex_(complex) CD4_Env_gp120/gp41_fusion_peptide_complex_(complex) Virion_with_CD4_bound_to_gp120_(complex) Env_oligomer_with_gp41(fusion_peptide)/gp120(released)_(complex) CD4_Env_gp120/gp41_hairpin_complex_(complex) Virion_with_exposed_coreceptor_binding_sites_(complex) gp41_homotrimer_with_fusion_peptide_inserted_into_membrane_(complex) CD4_Env_gp120/gp41_insertion_complex_(complex) gp41_homotrimer_(complex) Env_oligomer_with_gp41_hairpin_structure_formation_(complex) CD4_Env_gp120_with_exposed_coreceptor_binding_site_(complex) Trimeric_gp120_gp41_oligomer_(complex) Nucleocapsid CD4_Env_gp120_CCR5/CXCR4_complex_(complex) Env_oligomer_with_gp120(exposed)_(complex) CD4_Env_gp120/gp41_fusion_peptide_complex_CCR5_(complex) p66_subunit_of_RT Virion_with_gp41_fusion_peptide_in_insertion_complex_(complex) Vpu_protein Env_gp120_with_exposed_coreceptor_binding_site Virion_with_gp41_forming_hairpin_structure_(complex) Integrase CD4_gp120_gp41_membrane_complex_(complex) gp41_homotrimer_with_exposed_fusion_peptide_(complex) VIF CD4_Env_gp120/gp41insertion_complex_CCR5/CXCR4_(complex) Protease Env_gp120_protein p6_protein Env_gp41_fusion_peptide_inserted_into_host_membrane HIV-1_RNA_homodimer_(complex) Virion_with_CD4_gp120_bound_to_CCR5/CXCR4_(complex) Env_oligomer_with_gp120(second_conformation_change)_(complex) gp41_homotrimer_with_hairpin_structure_formation_(complex) PPIA
REACTOME_REACT_1835 NXF1 ALYREF Mature_intronless_derived_mRNA_TAP_Aly/Ref_complex_(complex) EIF4E Mature_Intronless_Transcript_Derived_mRNA_eIF4E_Complex_(complex) Nucleoplasmic_mature_intronless_derived_mRNA_TAP_Aly/Ref_complex_(complex)
PID_DNA_Damage_Reversal ENSEMBL_ENSGALP00000028424_MGMT MGMT
PID_Response_to_elevated_platelet_cytosolic_Ca2_ Protein_Kinase_C__conventional
PID_Pyruvate_metabolism PDHX PDHA1 pyruvate_dehydrogenase_complex_(complex) DLD pyruvate_dehydrogenase_E1_complex_(complex) pyruvate_dehydrogenase_E2_trimer_(complex) alpha-keto_acid_dehydrogenase_E3_homodimer_(complex) Basigin_bound_to_MCTs_(complex) DLAT pyruvate_dehydrogenase_E2_holoenzyme_(complex) PDHB BSG alpha-keto_acid_dehydrogenase_E3_holoenzyme_(complex)
PID_Synthesis_of_Ketone_Bodies D-beta-hydroxybutyrate_dehydrogenase_tetramer_(complex) BDH1
BIOCYC_PWY-7179 ADA
PID_Recycling_of_bile_acids_and_salts SLC10A2 SLC10A1 ALB bile_salts_and_acids_complexed_with_albumin_(complex) BAAT SLCO1B3 SLCO1B1 ABCB11 SLCO1A2 SLC27A5 ABCC3
PID_Amino_acid_transport_across_the_plasma_membrane SLC6A6 SLC7A8 SLC7A9 SLC7A6 SLC7A7 SLC7A5 SLC7A2 SLC7A3 SLC7A1 SLC7A5_SLC3A2_heterodimer_(complex) SLC7A7_SLC3A2_heterodimer_(complex) SLC36A2 SLC36A1 SLC7A8_SLC3A2_heterodimer_(complex) SLC6A19 SLC6A18 SLC16A10 SLC6A12 SLC6A15 SLC6A14 SLC38A5 SLC38A4 SLC38A1 SLC38A3 SLC38A2 SLC7A6_SLC3A2_heterodimer_(complex) SLC7A9_SLC3A1_heterodimer_(complex) SLC43A2 SLC43A1 SLC6A20 SLC3A2 SLC7A10_SLC3A2_heterodimer_(complex) SLC3A1 SLC7A10 SLC7A11 SLC7A11_SLC3A2_heterodimer_(complex) SLC1A4 SLC1A5
REACTOME_REACT_115896 NRG1/2_p-10Y-ERBB3_p-ERBB2_GRB7_(complex) Phosphorylated_ERBB2_ERBB3_heterodimers_(complex) GRB7
PID_Mineralocorticoid_biosynthesis CYP11B2 CYP11B1 CYP21A2
REACTOME_REACT_6761 (APC/C_Cdh1)-targeted_cell_cycle_proteins_(family) PLK1 phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) RPS27A multiubiquitinated_cell_cycle_protein_APC/C_Cdh1_complex_(complex) UBE2D1 SKP2 phospho-APC/C_Cdh1_complex_(complex) ANAPC11 ANAPC10 AURKA AURKB PTTG1 multiubiquitinated_Skp2_phospho-APC/C_Cdh1_complex_(complex) UBE2E1 cell_cycle_proteins_phospho-APC/C_Cdh1_complex_(complex) ANAPC1 CDC16 ANAPC2 ANAPC5 ANAPC4 ANAPC7 CDC27 CDC26 UBE2C FZR1 CDC23 CDC20 UBA52 UBB UBC ubiquitin_(family)
REACTOME_REACT_163796 SPAM1_Hyaluronic_acid_(complex) SPAM1
REACTOME_REACT_20642 CaMKII_delta/gamma_(family) CaMKII_alpha/beta_subunits_(family) CaMKII-Ca2+/Calmodulin_(complex) CaMKII_alpha/beta_(family) CALM1 CaMKII_gamma/delta_subunits_(family) CAMK2G CAMK2A CREB1 Active_Calmodulin_(complex) CAMK2B CaMKII_(complex) CaMKII_delta/gamma_subunits_(family)
PID_Activation_of_Rac Glypican-1_HSPG_(complex) RAC1 ROBO1 RAC1-GDP_(complex) SOS_PAK_Nck_Robo1_Slit2_Glypican_(complex) Slit2_Glypican-1_(complex) GPC1 SOS NCK SLIT2 RAC1-GTP_(complex) Pak_Nck_Robo1_Slit2_Glypican_(complex) Nck_Robo1_Slit2_Glypican_(complex) Robo1_Slit2_Glypican-1_(complex)
REACTOME_REACT_150401 Cleaved_collagen_type_XIII_(complex) Cleaved_collagen_type_XXV_(complex) Collagen_alpha-1(XIII)_chains_(family) Collagen_type_XVII_(complex) Cleaved_collagen_alpha-1(XII)_chains_(family) Cleaved_collagen_alpha-1(XIV)_chains_(family) Cleaved_collagen_alpha-1(XVI)_chains_(family) Cleaved_collagen_alpha-3(IX)_chains_(family) Cleaved_collagen_alpha-1(XXV)_chains_(family) Cleaved_collagen_alpha-2(IX)_chains_(family) Collagen_alpha-1(XXIII)_chains_(family) Collagen_type_XXV_(complex) Cleaved_collagen_alpha-1(IX)_chains_(family) Cleaved_collagen_type_XVII_(complex) Collagen_alpha-1(XXIII)_ectodomains_(family) COL26A1 Collagen_alpha-1(XXV)_ectodomains_(family) Collagen_type_XXIII_(complex) Collagen_alpha-1(XIX)_chains_(family) COL25A1 Collagen_alpha-1(XVII)_transmembrane_regions_(family) Collagen_alpha-1(XVII)_ectodomains_(family) COL18A1 COL9A2 COL9A3 COL19A1 Cleaved_collagen_type_XIV_(complex) Collagen_alpha-1(XXV)_chains_(family) COL23A1 Cleaved_tropocollagen_type_XVI_(complex) COL16A1 COL9A1 Collagen_type_XIII_(complex) Collagen_alpha-1(XVIII)_chain_endostatin-like_fragments_(family) COL17A1 COL15A1 Collagen_type_XIX_(complex) Collagen_alpha-1(XIII)_ectodomains_(family) Cleaved_collagen_type_IX_(complex) Cleaved_collagen_type_XXIII_(complex) Collagen_alpha-1(XIII)_chain_N-term_transmembrane_regions_(family) COL14A1 Endostatin-XV_(family) Collagen_alpha-1(XXIII)_transmembrane_regions_(family) COL13A1 Cleaved_collagen_type_XII_(complex) Collagen_alpha-1(XVII)_chains_(family) COL12A1
REACTOME_REACT_13443 TRAF6 NF-kB_p75NTR_ICD_TRAF6_(complex) NF-kB_complex_(complex) NGFR NFKB1 RELA
BIOCYC_PWY66-378 3_beta-hydroxysteroid_dehydrogenase/_delta_5-->4-isomerase_type_1_(complex) HSD17B3 CYP17A1 HSD3B1 HSD3B2 SRD5A2 SRD5A1 3_beta-hydroxysteroid_dehydrogenase/_delta_5-->4-isomerase_type_2_(complex) AKR1C3
REACTOME_REACT_330 BCL2L1 Bcl-XL_BH3-only_protein_complex_(complex) BCL2L11 Bcl2_BH3-only_protein_complex_(complex) BID tBID_BCL-2_(complex) BAD Bcl-XL_interacting_BH3-only_proteins_(family) BMF BBC3 Bcl-2_interacting_BH-3_only_proteins_(family) PMAIP1 BCL2
REACTOME_REACT_13781 NPC1L1 NPC1L1_ezetimibe_complex_(complex)
BIOCYC_PWY-4261 GPD_M_GPDH_M GK2 GK ATP_GLYCEROL_3_PHOSPHOTRANSFERASE_GLYCEROKINASE_GK GK3P
REACTOME_REACT_150361 RIP3_TRIF_activated_TLR3/TLR4_(complex) activated_TLR3/TLR4_TRIF_RIP1_FADD_pro-caspase-8_(complex) CASP8 RIPK1 activated_TLR3/TLR4_TRIF_RIP1_FADD_(complex) RIPK3 FADD TRIF_activated_TLR3/TLR4_(complex)
REACTOME_REACT_11051 GDI_proteins_(family) Inactivated_RhoGTPase_GDP_GDI_complex_(complex) RhoGTPase_GTP_(complex) ARHGDIG ARHGDIB RhoGTPase_GTP_Effectors_complex_(complex) ARHGDIA GDI2 GDI1 RhoGTPase_GDP_(complex)
REACTOME_REACT_147797 Sec23p_Sec24p_Complex_(complex) INSIG_oxysterol_(complex) INSIG1 Sar1b_GTP_Complex_(complex) SREBF1A/1C/2_SCAP_cholesterol_INSIG_(complex) SCAP Sec24_(family) INSIG_(family) SEC23A SREBF1A/1C/2_SCAP_Cop_II_Coat_(complex) SREBF1A/1C/2_SCAP_(complex) SREBF1A/1C/2_Dimer_(complex) SREBF1A/1C/2_SCAP_INSIG_oxysterol_(complex) SREBP1A_1C_2_(family) SREBF1A/1C/2_Importin_beta-1_(complex) SREBP1A/1C/2_Importin_beta-1_(complex) KPNB1 SEC24D SEC24A SEC24C SEC24B SAR1B SREBP1A_1C_2_cleaved_by_S2P_(family) SREBP1A_1C_2_cleaved_by_S1P_(family) SCAP_cholesterol_(complex) Sar1b_GTP_Sec23p_Sec24p_(complex) SREBF2 SREBF1 INSIG2 SCAP_tetramer_(complex)
PID_Aromatic_amines_can_be_N_hydroxylated_or_N_dealkylated_by_CYP1A2 CYP1A2
PID_Conjugation_of_benzoate_with_glycine xenobiotic/medium-chain_fatty_acid_CoA_ligases GLYAT
REACTOME_REACT_11200 AP2S1 CD8_Nef_AP-2_Complex_v-ATPase_Complex_(complex) ATP6V1H UniProt_P04601_nef CD8_Nef_Complex_(complex) AP2M1 AP2A1 AP-2_Complex_(complex) AP2A2 Adaptor_protein_complex_2_(AP-2)_large_adaptins_(family) CD8B AP2B1 Internalized_CD8_Nef_Clathrin-Coated_Pit_Adapter_Protein_v-ATPase_(complex)
REACTOME_REACT_549 14-3-3_proteins_p-S99-BAD_complex_(complex) 14-3-3_(dimer)_(complex) BCL2 BAD BAD_BCL-2_(complex)
REACTOME_REACT_11166 AP-1_Complex_(complex) AP1S2 AP1M2 AP1G1 HLA-A AP1M1 Nef_class_I_MHC_complex_Ap-1_PACS-1_Complex_(complex) B2M AP-1_mu_(family) AP1S1 AP-1_sigma_(family) AP1S3 Nef_class_I_MHC_complex_AP-1_PACS-1_Complex_(complex) AP1B1 UniProt_P04601_nef class_I_MHC_complex_(complex) PACS1 Nef_class_I_MHC_complex_(complex)
REACTOME_REACT_19187 GNS AP1S2 AP1M2 AP1M1 CLTC AP-1_mu_(family) AP1S1 AP-1_Complex_(complex) ARRB1 TXNDC5 SH3GL2 BLOC1S1 ARF1 DNM2 Clathrin_Triskelion_(complex) DNASE2 AP1B1 HSPA8 AP1S3 Lysosome_Cargo_(family) HSC70_Auxillin_Complex_(complex) CTSZ ARF1/GTP_(complex) VAMP2 Lysosome_Destined_Cargo_AP-1_beta-Arrestin-1_Vamp_Complex_(complex) Lysosome_Cargo_AP-1_Beta-arrestin_Clathrin_Triskelion_Vamp_Complex_(complex) VAMP7 AP1G1 DNAJC6 Vamp_(family) Lysosome_Destined_Cargo_AP-1_Beta-arrestin_Vamp_Clathrin_Triskelion_Dynamin_Endophilin_Complex_(complex) VAMP8 AP-1_sigma_(family) Lysosome_Destined_Cargo_(family) CLTA ARF1/GDP_(complex) Lysosome_Destined_Cargo_AP-1_Arf1-GTP_beta-Arrestin-1_Vamp_Complex_(complex) M6PR
REACTOME_REACT_1966 ADAR2_homodimer_(complex) ADAR ADARB1 ADAR1_homodimer_(complex) Editosome_(ADAR2)_complex_(complex) Editosome_(ADAR1)_complex_(complex)
BIOCYC_PWY-5326 sulfite_oxidase_(complex) SUOX
REACTOME_REACT_11049 GJA1 Connexin_43_connexon_in_Golgi_transport_vesicle_(complex) connexons_in_Golgi_transport_vesicle_docked_to_microtubules_(complex)
PID_Conversion_from_APC_C_Cdc20_to_APC_C_Cdh1_in_late_anaphase phospho-APC/C_Cdh1_complex_(complex) phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) CDC16 CDC27 CDC23 UBE2C FZR1 ANAPC11 ANAPC10 UBE2E1 UBE2D1 CDC26 ANAPC1 ANAPC2 ANAPC5 ANAPC4 ANAPC7
BIOCYC_PWY-5661 HKDC1 glucose-1-phosphate_guanylyltransferase GCK PGM1 PGM2
REACTOME_REACT_115846 UniProt_Q30KQ3_Beta-defensin_117 Beta-defensins_(family) DEFB1 CCR2 CCR6 Beta_defensins_4A_103_(family) DEFB116 DEFB106A DEFB114 DEFB115 Beta-defensins_1_4A_103_CCR6_(complex) DEFB113 DEFB110 DEFB104A DEFB108B DEFB118 DEFB119 DEFB130L Beta_defensin_103_TLR1_TLR2_(complex) DEFB134 DEFB135 DEFB136 DEFB131 DEFB132 DEFB133 Beta-defensins_anionic_phospholipids_(complex) Beta_defensins_1_4A_103_(family) Beta_defensins_4A_103_CCR2_(complex) DEFB112 DEFB4B DEFB107B TLR1_TLR2_(complex) TLR2 UniProt_Q5FWG5_TLR1 DEFB127 DEFB129 DEFB128 DEFB105A DEFB126 DEFB125 DEFB124 DEFB123 DEFB103B DEFB121
PID_COPI_Mediated_Transport COPZ1 COPA Coatomer_Arf1-GTP_GAP_Complex_(complex) COPE ARF1 COPG1 ARCN1 Coatomer_(complex) ARFGAP1 COPB1 ARF1/GTP_(complex) COPB2 GBF1 ARF1/GDP_(complex) Coatomer_Arf1-GTP_Complex_(complex)
PID_Synthesis_of_dolichyl_phosphate_glucose ALG5
REACTOME_REACT_20593 R-Ras-GTP_(complex) CREB1 RRAS Activated_B-raf_complex_(complex) MAPK1 BRAF
PID_alkpathway SMAD6 RFC1 BMPR1A MYL2 TGF-beta/TGF-beta-R1/TGF-beta-R2_(complex) NKX2-5 MAP3K7 BMP NPPB NPPA TGFBR2 TGFBR1 CSX/GATA4_(complex) TGF-beta SMAD GATA4 BMP/BMPR-II/ALK3_(complex) NOG MEF2C CHRD BMPR2 ATF-2/CSX/GATA4_(complex) ATF2
PID_Signalling_to_ERK5 MAPK7 MAP2K5
PID_Alternative_complement_activation C3(H2O)_Factor_Bb_(complex) C3b_Factor_Bb_complex_(complex) Complement_factor_3(H2O)_(complex) CFD CFB C3(H2O)_Factor_B_(complex) C3 C3b_Factor_Bb_Properdin_complex_(complex) C3b_(complex) C3b_Factor_B_complex_(complex)
PID_pyk2pathway CRKL HRAS MAPK14 MAP2K2 PLCG1 MAP2K4 RAF1 MAPK3 SHC/GRB2/SOS-1_(complex) MAP3K1 JUN CaM/Ca_++_(complex) PKC GPCR MAPK1 MAPK8 SRC SHC1 RAC1 PYK2/SRC/GRB2/SOS-1_(complex) BCAR1 PTK2B MAP2K3 GNAQ SOS1 PYK2/SRC/P130cas/CRKL_(complex) MAP2K1 GPCR/G-alpha-q_(complex) GRB2 CaM PYK2/SRC_(complex) PAK1
PID_Synthesis_of_UDP_N_acetyl_glucosamine UAP1 GNPNAT1 GNPNAT1_homodimer_(complex) PGM3 UAP1_homodimer_(complex) GFPT1/2
PID_Pausing_and_recovery_of_elongation NELFB P-TEFb_complex_(complex) TCEB1 NELFA NELFE TCEB3 Paused_processive_elongation_complex_(complex) CCNT1 Processive_elongation_complex_(complex) Elongin_B_C_complex_(complex) CCNT2 RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) SSRP1 phospho-Spt5 CDK9 TCEB2 FACT_complex_(complex) ELL SUPT16H Elongin_Complex_(complex) TCEA1 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L CTDP1 POLR2I POLR2H POLR2K POLR2J GTF2F1 NELFCD GTF2F2 NELF_complex_(complex) SUPT4H1 DSIF_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex)
REACTOME_REACT_13462 caspase-3-cleaved_DFF45_(117_224)_DFF40_complex_(complex) HMGB2 HMGB1 HMGB1/HMGB2-_bound_chromatin_(complex) Histone_H1_(family) Histone_H1_bound_chromatin_DNA_(complex) DFF45_DFF40_complex_(complex) DFF_associated_with_the_importin-alpha_importin-beta_complex_(complex) DFF40_homodimer_(complex) DFF40_associated_with_chromatin_(complex) importin-alpha_importin-beta_(complex) H1F0 Caspase_cleaved_DFF45_(117)_(complex) KPNB1 DFFA DFFB HIST1H1D HIST1H1E active_caspase-3_(complex) HIST1H1A HIST1H1B HIST1H1C DFF_cleaved_DNA_(complex) HMGB1/HMGB2_(family) CASP3 importin-alpha_importin-beta_complex_(complex) KPNA1
PID_Adherens_junctions_interactions Classic_Cadherin Necl-1/Necl-2/Necl-3_trans_homodimer_(complex) Cadherin_trans-homodimer_(complex) Cadherin_Catenin_complex_(complex) Nectin_trans_homodimer_(complex) JUP MLLT4 Afadin_F-actin_(complex) CTNND1 Nectin_afadin_complex_(complex) CTNNA1 Nectin_cis-homodimer_(complex)
PID_Nonhomologous_End_joining__NHEJ_ DNA-PK_XRCC4_DNA_ligase_IV_DNA_complex_associated_with_ligatable_DNA_ends_(complex) DNA-PK_DNA_DNA-PK_DNA_complex_(complex) LIG4 DNA-PK_DNA_complex_(complex) XRCC4 PRKDC XRCC5 Ku_DNA_double-strand_break_ends_(complex) Ku70_Ku80_heterodimer_(complex) XRCC6
PID_Beta_oxidation_of_myristoyl_CoA_to_lauroyl_CoA HADHB LCAD_acyl-CoA_dehydrogenase_homotetramer_(complex) HADHA ACADL Trifunctional_Protein_(complex)
BIOCYC_PWY-7177 ENTPD1 CTPS1 CANT1 CTPS2
REACTOME_REACT_8030 PCNA RPA_heterotrimer_(complex) DNA2 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_RPA_heterotrimer_(complex) RPA1 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_RPA_heterotrimer_dna2_(complex) POLD2 RPA3 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_(complex) Processive_complex_loaded_on_telomere_nicked_DNA_from_adjacent_Okazaki_fragments_(complex) POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 PCNA_homotrimer_(complex) POLD4 Processive_complex_loaded_on_telomere_Okazaki_fragments_Remaining_Flap_(complex) RPA2
PID_Generation_of_second_messenger_molecules CD3_epsilon__CD3_gamma_with_phosphorylated_ITAM_(complex) Antigen-bearing_MHC_Class_II__TCR_with_phosphorylated_ITAMs_CD4_(complex) p-SLP-76_ADAP_Ena/VASP_(complex) CD4 PLCG1 CD247 SLP-76_bound_to_Gads_LAT_(complex) PAK FYB CD3_zeta_dimer_with_phosphorylated_ITAMs_(complex) Activated_ZAP-70_(complex) CD3_epsilon__CD3_delta_with_phosphorylated_ITAMs_(complex) ITK_bound_to_SLP-76_Gads_LAT_(complex) phosphorylated_SLP-76_Gads__LAT_(complex) Ena/VASP_proteins GRAP2 ZAP70 TCR_chain_alpha T-cell_receptor_(complex) Activated_PLC_gamma1_bound_to_PIP2_(complex) Gads_bound_to_LAT_at_phosphotyrosine_(complex) MHC_Class_II_bearing_antigen_peptide_(complex) p-SLP-76_NCK1_(complex) LCP2 WAS ITK p-SLP-76_NCK_PAK_(complex) NCK1 PLC-gamma1_bound_to_SLP-76_Gads_LAT_(complex) TCR_chain_beta p-SLP-76_ADAP_(complex) CD3E T-cell_receptor_complex_with_phosphorylated_ITAMs_(complex) PLC-gamma1_bound_to_LAT_at_pY312_(complex) p-SLP-76_NCK1_WASP_(complex) LAT CD3D LCK CD3G
PID_ngfpathway NGF SHC1 SOS1 FOS GRB2 HRAS JUN PIK3CA PLCG1 MAPK3 MAP2K1 ELK1 NGF/NGF_R/NGF/NGF_R_(complex) NGFR PIK3R1 PI3K_(complex) MAPK8 AP-1_(complex) SHC/GRB2/SOS-1_(complex) CSNK2A1
BIOCYC_PWY-6576 HYAL1 iduronate_2-sulfatase_complex_(complex) HEXA beta_hexosaminidase_S_(complex) SPAM1 iduronate_2_sulfatase_precursor beta-hexosaminidase_A_(complex) beta-hexosaminidase_B_(complex) IDUA
REACTOME_REACT_1949 CDT1_CDC6_ORC_origin_complex_(complex) RPS27A geminin_ubiquitin_complex_(complex) Orc2_associated_with_MCM8_(complex) ORC6 ORC2 ORC4 ORC5 CDT1 ORC3 ORC1 UBA52 CDC6 UBB UBC GMNN ORC_origin_(complex) ubiquitin_(family) CDC6_ORC_origin_complex_(complex) MCM8
PID_Mature_Notch_receptor_trafficks_to_plasma_membrane NTM-NEC_3_heterodimer_(complex) NTM-NEC_2_heterodimer_(complex) NOTCH4 NOTCH1 NOTCH2 NOTCH3 NTM-NEC_4_heterodimer_(complex) NTM-NEC_1_heterodimer_(complex)
PID_pgc1apathway HDAC5 SLC2A14 PPARGC1A MEF2 CAMKII_(8)_(complex) CaMKI/CaM/Ca_++_(complex) CAMK4 CaMKI CaMKK ESRRA PGC1-alpha/PPAR-alpha_(complex) 14-3-3/HDAC5_(complex) MEF2/PGC1-alpha_(complex) PPARA CAMKII/CaM/Ca_++/CaM/Ca_++/CaM/Ca_++/CaM/Ca_++_(complex) CAMKII/CaM/Ca_++/CaM/Ca_++_(complex) CamKIV/CaM/Ca_++_(complex) CAMKII CaM/Ca_++_(complex) CaM PPP3CA CaMKK/CaM/Ca_++_(complex) PPP3CC Calcineurin_(complex) YWHAH
REACTOME_REACT_9003 Cyclin_E/A_Cdk2_(complex) UBC SKP2 SCF(Skp2)_Cks1_complex_(complex) SKP1 CDKN1B CDKN1A RPS27A Cyclin_E/A_Cdk2_phospho-p27/p21_(complex) CKS1B Cyclin_E/A_Cdk2_phospho-p27/p21_SCF(Skp2)_Cks1_complex_(complex) CDK2 UBA52 UBB SCF(Skp2)_complex_(complex) Cyclin_E/A_Cdk2_multiubiquitinated_phospho-p27/p21_SCF(Skp2)_Cks1_complex_(complex) CUL1 UBIQ_HUMAN_(family) phospho-p27/p21_(family)
REACTOME_REACT_150260 CK2_Phosphorylated_Condensin_I_(complex) SMC2 SMC4 NCAPD2 SMC2_SMC4_p-T1339_1384_1389-NCAPD2_p-NCAPH_p-T308_332-NCAPG_(complex) NCAPH NCAPG SMC2_SMC4_NCAPD2_NCAPH_NCAPG_(complex)
PID_C6_deamination_of_adenosine A_to_I_edited_RNA_Editosome_(ADAR1)_complex_(complex) ADAR2_homodimer_(complex) A_to_I_edited_RNA_Editosome_(ADAR2)_complex_(complex) ADAR ADARB1 ADAR1_homodimer_(complex)
PID_Steroid_hormones CYP17A1 CYP11B1 CYP21A2
BIOCYC_CYSTEINE-DEG-PWY GOT1 CDO1
BIOCYC_PWY0-1295 UPP2 UPP1 AICDA cytidine_aminohydrolase_(complex) CDA
REACTOME_REACT_150180 Collagen_type_II_type_IX_fibril_(complex) ITGA6 CD151 Collagen_type_VII_fibril_Laminin-332_(complex) LAMB3 ITGB4 Collagen_type_XV_(complex) Collagen_type_XVIII_(complex) Collagen_type_I_II_XII_XIV_fibrils_(complex) BPAG1e_Plectin_(complex) LAMA3 Laminin-332_(complex) Collagen_type_X_type_II_fibrils_(complex) Collagen_type_XI_fibril_Collagen_type_II_fibril_(complex) COL18A1 DST PLEC Type_I_hemidesmosome_complex_(complex) LAMC2 COL15A1 Collagen_alpha-1(XV)_chains_(family) Collagen_alpha-1(XVIII)_chains_(family) Integrin_alpha6beta4_(complex) Collagen_type_XVII_fibril_Integrin_alpha6beta4_(complex)
PID_Dissolution_of_Fibrin_Clot urokinase_plasminogen_activator_(two-chain)_(complex) fibrin_multimer__crosslinked_tissue_plasminogen_activator_(two-chain)_plasminogen_activator_inhibitor_1_(complex) PLAUR fibrin_multimer__crosslinked_tissue_plasminogen_activator_(two-chain)_plasminogen_(complex) alpha-2-antiplasmin_plasmin_(complex) urokinase_plasminogen_activator_(two-chain)_uPAR_(complex) SERPINE1 fibrin_multimer__crosslinked_tissue_plasminogen_activator_(one-chain)_(complex) histidine-rich_glycoprotein_plasminogen_(complex) Plasmin_(complex) PAI-2_urokinase_plasminogen_activator_(two-chain)_uPAR_(complex) PAI-1_urokinase_plasminogen_activator_(two-chain)_uPAR_(complex) plasminogen_histidine-rich_glycoprotein_(complex) tissue_plasminogen_activator_(two-chain)_(complex) PLAU PLAT fibrin_multimer__crosslinked_tissue_plasminogen_activator_(one-chain)_plasminogen_(complex) SERPINF2 HRG SERPINB2 urokinase_plasminogen_activator_(one-chain)_uPAR_(complex) fibrin_multimer__crosslinked_tissue_plasminogen_activator_(two-chain)_(complex) PLG fibrin_multimer__crosslinked_tissue_plasminogen_activator_(one-chain)_plasminogen_activator_inhibitor_1_(complex)
REACTOME_REACT_408 RPA_heterotrimer_(complex) RAD51_RAD52_DNA_double_strand_break_end_complex_(complex) RPA1 RPA3 RPA2 RAD52 RAD51 RAD51_resected_ends_of_DNA_double-strand_break_(complex) RAD51_RPA_complex_(complex)
PID_Inositol_transporters SLC5A3 SLC5A11 SLC2A13
PID_npp1pathway collagen_IV_(complex) ANKH ENPP1 COL4A6 COL4A5 COL4A4 COL4A3 COL4A2 COL4A1 SPP1 IBSP Hydroxyapatite/BSP/collagen_IV/TNAP/NPP1_(complex) ALPL
PID_Glucose_metabolism GPI 6-phosphofructo-2-kinase/fructose-2_6-biphosphatase_1_homodimer_(complex) PFKFB1 TPI1 triosephosphate_isomerase_dimer_(complex) phosphoglycerate_kinase_1_complex_(complex) phosphoPFKFB1_dimer_(complex) glucose_6-phosphate_isomerase_dimer_(complex) PGK1
PID_Cell_surface_interactions_at_the_vascular_wall JAM-C_homodimer_(complex) Alpha_5_Beta_1_Fibronectin_receptor_bound_to_Fibronectin_(complex) Integrin_alphaXbeta2_(complex) AMICA1 ITGA4 ITGA5 FceRI_gamma_dimer_(complex) CD84 CD244 CD84_Homodimer_(complex) ITGB2 GPVI_FceRI_gamma_FYN_LYN_(complex) CD2 SELPLG THBD Fibronectin_dimer_(complex) CD48_bound_to_CD244_(complex) FCER1G APOB OLR1_bound_to_oxidized_LDL_(complex) JAM-B_bound_to_JAM-C_(complex) FYN CD177 MAC-1_bound_to_JAM-C_(complex) MERTK MERTK_ligands Integrin_alpha_Xbeta_2_bound_to_JAM-C_(complex) LFA-1_bound_to_JAM-A_(complex) GP6 P-selectin_bound_to_its_ligand_(complex) CD58 ITGB1 CD58_bound_to_CD2_(complex) GPVI_FceRI_gamma_FYN_LYN_Collagen_I_(complex) Integrin_CD11a-CD18_(LFA-1)_(complex) CD48 JAM2 JAM3 VLA-4_bound_to_JAM-B_(complex) CD47 CXADR_bound_to_JAML_(complex) JAM-B_homodimer_(complex) TREM-1_bound_to_its_ligand_(complex) activated_thrombin_thrombomodulin_(complex) Platelet_Factor_4 GP_VI___FceRI_gamma_dimer_(complex) low-density_lipoprotein_complex_(complex) Activated_thrombin_(factor_IIa)_(complex) JAM-A_Homodimer_(complex) LYN F11R Selectin ITGAX CXADR F2 CD47_bound_to_its_ligand_(complex) OLR1 FN1 PECAM1 PECAM-1_bound_to_CD177_(complex) MERTK_bound_to_its_ligand_(complex) VLA-4_(complex) ITGAL ITGAM TREM1 Integrin_MAC-1_(complex) Alpha_5_Beta_1_Fibronectin_receptor_(complex) PROC PTPN11
PID_Transcription_of_the_HIV_genome linear_duplex_viral_DNA_(complex) HIV-1_promoter_TFIID_TFIIA_TFIIB_Pol_II_TFIIF_complex__(complex) HIV-1_open_pre-initiation_complex_(complex) NELFB P-TEFb_complex_(complex) ERCC2 ERCC3 TAF9 TFIID_(complex) CTDP1 POLR2B RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex) TAF11 TAF10 GTF2A1 GTF2A2 HIV-1_closed_pre-initiation_complex_(complex) CCNT1 Elongin_B_C_complex_(complex) GTF2E1 GTF2E2 CCNT2 HIV-1_promoter_TFIID_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) P-TEFb(Cyclin_T1_Cdk9)_complex_(complex) phospho-Spt5 GTF2B SSRP1 TAF4B POLR2K Tat_P-TEFb(Cyclin_T1_Cdk9)_complex_(complex) TCEB2 RNA_Polymerase_II_(unphosphorylated)_TFIIF_complex_(complex) FACT_complex_(complex) TCEA1 Elongin_Complex_(complex) SUPT16H TAF1 TFIIA_(complex) NELFA ELL TAF6 GTF2H3 GTF2H2 GTF2H1 TCEB3 RNA_Polymerase_II_holoenzyme_complex_(unphosphorylated)_(complex) TCEB1 GTF2H4 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C CDK9 TAT_protein POLR2L MNAT1 NELFE POLR2I POLR2H HIV-1_processive_elongation_complex_(complex) POLR2J TAF13 TAF5 TAF4 GTF2F1 NELF_complex_(complex) NELFCD GTF2F2 TBP HIV-1_Tat-containing_processive_elongation_complex_(complex) TFIIH_(complex) HIV-1_promoter_TFIID_TFIIA_TFIIB_complex_(complex) SUPT4H1 TAF12 TFIIE_(complex) CDK7 DSIF_complex_(complex) CAK_(complex) CCNH Integrated_provirus_(complex)
BIOCYC_PWY66-385 TYMS SHMT2 dihydrofolate_reductase-like_protein_1
PID_Reverse_Transcription_of_HIV_RNA minus_sssDNA_primer_for_minus_strand_DNA_extension_(complex) VIF Matrix EMBL_AF033819_EMBL_AF033819 p51_subunit_of_RT p6_protein Reverse_Transcriptase_heterodimer_(complex) Rev Vpu_protein RTC_with_extending_minus_strand_DNA_(complex) p66_subunit_of_RT Integrase PPIA Vpr_protein
PID_Complement_cascade C2 C5b_(complex) C4A C5 C4b_C2b_complex_(complex)
BIOCYC_PWY3DJ-12 DEGS2 CERS1 KDSR SPTLC2 SPTLC3 SPTLC1 serine_palmitoyltransferase_IIA_(complex) serine_palmitoyltransferase_IA_(complex) SPTSSA
REACTOME_REACT_118632 N-ter_TLR9_dimer_(complex) full_length_TLR8_(complex) Apo-GP96_dimer_(complex) HSP90B1 intracellular_TLR_UNC93B1_(complex) TLR3 FL-TLR7_dimer_(complex) CNPY3 TLR7 full-length_TLR9_dimer_(complex) TLR7/8/9_(family) UNC93B1 folded_FL-TLR7/8/9_(complex) TLR8 TLR9 ATP-bound_Gp96_dimer_CNPY3_TLR7/8/9_(complex) C-terminus_Toll_like_receptor_9_(TLR9)_dimer_(complex)
BIOCYC_ALANINE-SYN2-PWY GPT GPT2
PID_rxr_vdr_pathway VDR FAM120B MED1 RXRs/NUR77/BCL2_(complex) NCOR2 RARs/THRs/DNA/Src-1_(complex) NCOA1 RXRs/VDR/DNA/Vit_D3_(complex) RARs/THRs/DNA/SMRT_(complex) RPS6KB1 THRs RARS NR1H4 RXRs/PPAR/9cRA/PGJ2/DNA_(complex) VDR/Vit_D3/DNA_(complex) DNA LXRs NR4A1 RXRA RXRs/PPAR_(complex) RXRs/RXRs/DNA/9cRA_(complex) RXRs/LXRs/DNA/Oxysterols_(complex) RXRs/NUR77_(complex) PPAR/PGJ2_(complex) RXRs/FXR/9cRA/MED1_(complex) RXR_alpha/CCPG_(complex) PPAR BCL2 RXRs
BIOCYC_PWY66-391 peroxisomal_3-ketoacyl-CoA_thiolase_(complex) ACOX1 SLC27A2 ACOX2 ACSL3 SCP2 ACSL1 ACSL6 ACSL4 ACSL5 ACAA1 ACSBG1 ACSBG2 long_fatty_acyl-CoA_synthetase_2 HSD17B4 EHHADH DBP_(complex)
PANTHER_P00041 Homer IP3R mGluR5 Complex_(GTP/G-Protein)_(complex) GluR5 Complex_(mGluR1/mGluR5/_Glutamate/Homer/_G-Protein/GDP)_(complex) mGluR1_(complex) Complex_(GluR5/Glutamate)_(complex) Complex_(mGluR1/Homer)_(complex) PKC Complex_(mGluR1/mGluR5/_Homer/G-Protein/_GDP)_(complex) PKA PLC NMDA Complex_(mGluR5/Homer)_(complex) G-Protein Complex_(NMDA/Glutamate)_(complex)
PID_Proton_coupled_monocarboxylate_transport Monocarboxylate_transporters
PID_pmlpathway DAXX SIRT1 PRAM1 TP53 PML/SUMO1_(complex) PML/sp100/SUMO1_(complex) RB1 PML SUMO1 PML/sp100/SUMO1/p53(+1)_(complex) HSV-ICP0 CMV-IE1 PML/sp100/DAXX_(complex) PML/sp100/SUMO1/p53_(complex) PML/sp100/RB_(complex) CREBBP SP100
PID_Mitochondrial_transcription_termination MTERF mTERF_mitochondrial_transcription_termination_sequence_(complex)
PID_Activation_of_Chaperones_by_IRE1alpha IRE1_homodimer_(complex) IRE1_homodimer_(phosphorylated)_(complex) ACADVL HSPA5 TPP1 ENSEMBL_Homo_sapiens_TRANSCRIPT_ENST00000216037_Xbp1_mRNA_(unspliced) NFYA Xbp1_mRNA_(spliced) Proteins_Upregulated_by_XBP1(S) IRE1_homodimer_(phosphorylated)_ADP_(complex) BiP_unfolded_protein_complex_(complex) ATP6V0D1 ERN1 XBP1
REACTOME_REACT_163785 Metabotropic_glutamate_receptors_L-Glutamate_(complex) TAS2R20 GPRC6A_receptor_GPRC6A_ligands_(complex) GABAB_receptor_GABA_(complex) GABBR1 GABBR2 T2Rs_Bitter-tasting_compounds_(complex) Sweet_taste_receptor_(complex) TAS2R60 TAS2R50 Umami_taste_receptor_(complex) TAS2R30 CASR TAS2R38 TAS2R39 TAS2R19 T2Rs_(family) TAS2R14 TAS2R16 TAS2R31 TAS2R10 TAS2R13 Umami_taste_receptor_L-glutamate_(complex) GPRC6A GABAB_receptor_(complex) TAS2R8 TAS2R9 Sweet_taste_receptor_sweet_taste_stimuli_(complex) TAS2R7 CASR_Calcium_(complex) TAS2R5 TAS2R3 TAS2R1 TAS2R43 TAS2R42 TAS2R41 TAS2R40 TAS2R46 TAS2R45 TAS1R1 TAS1R3 TAS1R2 TAS2R4
REACTOME_REACT_23898 YWHAZ 14-3-3_beta__zeta_(family) RAF1 RAP1/GDP_(complex) RAP1B RAP1A RAPGEF4 p(S7)-Rap1_GTPase-activating_protein_2_14-3-3beta__zeta_(complex) Rap1_cAMP-GEFs_cAMP_(complex) RAPGEF3 YWHAB Rap1-GTP_Raf1_(complex) RAP1/GTP_(complex) RAP1GAP2 RAP1_(family) Rap1_cAMP-GEFs_(family)
REACTOME_REACT_1178 Platelet_dense_granule_membrane_components_(family) POTEKP HSPA5 Platelet_releasate_(inferred)_cytosolic_proteins_(family) SCG3 HABP4 Platelet_releasate_cytosolic_proteins_(family) APOA1 Platelet_releasate_secretory_granule_proteins_(family) CALM2 CAP1 TLN1 BRPF3 TTN TF CD63 WDR1 SOD1 VCL LAMP2 CFL1 TUBA4A PLEK PSAP CALU PFN1 FLNA SELP PPIA
PID_Influenza_Life_Cycle EMBL_AF389121_H1N1_Genomic_RNA_Segment_7 EMBL_AF389119_H1N1_Genomic_RNA_Segment_5 EMBL_AF389120_H1N1_Genomic_RNA_Segment_6 Ribonucleoprotein_(RNP)_Complex_(complex) Influenza_A_Viral_Envelope_(complex) palmitylated_M2_Tetramer_(complex) UniProt_P03485_M EMBL_AF389117_H1N1_Genomic_RNA_Segment_3 UniProt_P03466_NP UniProt_P03431_PB1 UniProt_P03508_NS UniProt_P03428_PB2 EMBL_AF389122_H1N1_Genomic_RNA_Segment_8 UniProt_P03452_HA UniProt_P03433_PA EMBL_AF389115_H1N1_Genomic_RNA_Segment_1 EMBL_AF389118_H1N1_Genomic_RNA_Segment_4 UniProt_P06821_M Gycosylated_NA_Tetramer_(complex) Sialic_Acid_Bound_Influenza_A_Viral_Particle_(complex) EMBL_AF389116_H1N1_Genomic_RNA_Segment_2 UniProt_P03468_NA Cleaved_HA_Influenza_A_Viral_Particle_(complex) Cleaved_Trimeric_palmitylated_HA_(complex)
Pathway_a00c0fc2ef0619db554c4d8af120818f.owl GPI PFKFB1 PP2A-ABdeltaC_complex_(complex) TPI1 PF2K-Pase1_homodimer_(complex) triosephosphate_isomerase_dimer_(complex) phosphoglycerate_kinase_1_complex_(complex) phosphoPFKFB1_dimer_(complex) glucose_6-phosphate_isomerase_dimer_(complex) PGK1
PID_ERKs_are_inactivated PP2A-ABdeltaC_complex_(complex) Phospho-ERK1/2/5 ERK1/2/5
REACTOME_REACT_150471 AHCTF1 PLK1 CCAN_network_(complex) CENP-(H_I__K)_complex_(complex) Securin_Separin_(complex) KIF2A KIF2C KIF2B Cleaved_Cohesin_PDS5_p-CDCA5_WAPAL_Sister_Centromeres_Kinetochores_Microtubules_(complex) BUB1B ANAPC11 ANAPC10 PDS5A/B_(family) ESPL1 MAPRE1 CENPO CENPN CENPM CENPL CENPK CENPI CENPH CENPF CENPE CENP-O_complex_(complex) CENPC RANGAP1 CENPA Cleaved_Cohesin_PDS5_WAPAL_(complex) CDC20_Phospho-APC/C_(complex) CENPT PAFAH1B1 CENPQ CENPP NUF2 PPP2CA ubiquitin_(family) PPP2CB UBB Cohesin_Complex_(complex) Chromosome_passenger_complex_(complex) SPC24 NSL1 UBC SEH1L ZWINT RPS27A PDS5A NUP85 PDS5B MIS12 NDC80_complex_(complex) B9D2 XPO1 CDC16 RZZ_complex_(complex) phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) Mitotic_checkpoint_complex_(complex) SMC1A INCENP Nup107-160_complex_(complex) BUB3 STAG2 SEC13 STAG1 UBE2E1 SGOL1 SGOL2 ANAPC1 ZWILCH ANAPC2 ANAPC5 ANAPC4 ANAPC7 SPDL1 CDC27 CDC26 UBE2C CDC20_phospho-APC/C_K11polyUb-Securin_complex_(complex) PP2A_(complex) CDC20 SPC25 PPP2R5D PPP2R5E PPP2R5A PPP2R5B Cleaved_Cohesin_(complex) NUP133 DSN1 NDC80 Kinetochore_(complex) ERCC6L KNTC1 PTTG1 RANBP2 PP2A-subunit_A_(family) NUP107 ZW10 UBE2D1 TAOK1 Separin_Autocleaved_(complex) KMN_network_(complex) Cdc20_phosph-APC/C_Securin_complex_(complex) WAPAL SMC3 PPP2R1A PPP2R1B MAD2L1 RPS27 CDC23 BIRC5 PP2A-catalytic_subunit_C_(family) ITGB3BP BUB1 NDE1 APITD1 MAD1L1 NUP98 NUDC NUP43 SKA1 CLIP1 SKA2 AURKB CDCA5 CDCA8 Mis12_complex_(complex) CLASP2 CLASP1 RAD21 NUP160 KIF18A PP2A_regulatory_subunit_B56_(family) CASC5 NDEL1 Sister_Centromere_Kinetochore_Microtubules_(complex) RCC2 PPP1CC PMF1 NUP37 MLF1IP PPP2R5C CKAP5
PID_bcellsurvivalpathway DPF2 CASP7 ZBTB7A CASP3 PI3K_(complex) ITGA1 BIRC5 CCT4 ITGB1 PIK3CA PIK3R1 Integrin-alpha/Integrin-beta/ECM_(complex) PDPK1 ECM
REACTOME_REACT_169318 3_cytosolic_halocarboxylases_(complex) PCCA ACACA mitochondrial_holocarboxylases_(complex) ACACB PCCB methylcrotonyl-CoA_carboxylase_complex_(complex) 4x(Btn-PC_Mn2+)_(complex) 4x(PC_Mn2+)_(complex) PC biotinylated_propionyl-CoA_carboxylase_dodecamer_(complex) propionyl-CoA_carboxylase_protomer_(complex) Btn-ACACA_2Mn2+_(complex) ACACB_2Mn2+_(complex) MCCC2 MCCC1 Btn-ACACB_2Mn2+_(complex)
PID_Regulation_of_Glucokinase_by_Glucokinase_Regulatory_Protein NUP88 AAAS NUP133 NUP85 NUP62 SEH1L NUP98 NUP43 NUP188 NUP214 NUP210 NUP160 RANBP2 glucokinase_glucokinase_regulatory_protein_complex_(complex) POM121 NUP107 Nup107_Complex_(complex) GCK NUP93 GCKR TPR Nup62_Complex_(complex) NUPL1 NUPL2 NUP50 NUP54 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 NUP153 NUP155 NUP205 RAE1
BIOCYC_PWY-5921 QRSL1 TRNA(GLN) L-GLUTAMINYL-TRNA(GLN) glu-tRNA(gln) PET112
PID_tidpathway LIN7A DNAJA3 TAX1BP3 IFN-gamma/IFN-gamma_R-alpha/IFN-gamma_R-beta/JAK2/TID1_(complex) TP53 IKKs WT1 IFNG TIP1/VELI1/TAX/TRX_(complex) IFN-gamma_R-beta RB1 CNTN2 HSPA1A JAK2 IFNGR1 IFN-gamma/IFN-gamma_R-alpha/IFN-gamma_R-beta/JAK2_(complex) USH1C IFN-gamma_R-alpha/IFN-gamma_R-beta/JAK2/TID1/HSP70_(complex) TID1/HSP70_(complex)
PID_RNA_Polymerase_II_Transcription_Pre_Initiation_And_Promoter_Opening ERCC2 ERCC3 TAF13 TAF12 TAF11 TAF10 GTF2A1 GTF2A2 GTF2E1 GTF2E2 RNA_Polymerase_II_(unphosphorylated)_TFIIF_complex_(complex) pol_II_promoter_TFIID_TFIIA_TFIIB_complex_(complex) GTF2B TAF4B TFIIE_(complex) pol_II_promoter_TFIID_TFIIA_TFIIB_Pol_II_TFIIF_complex_(complex) TFIIA_(complex) GTF2H3 GTF2H2 GTF2H1 RNA_Polymerase_II_holoenzyme_complex_(unphosphorylated)_(complex) GTF2H4 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L MNAT1 POLR2I POLR2H POLR2K POLR2J TAF6 TAF5 TAF4 GTF2F1 pol_II_promoter_TFIID_complex_(complex) TAF1 GTF2F2 TBP pol_II_closed_pre-initiation_complex_(complex) TAF9 TFIIH_(complex) pol_II_promoter_TFIID_TFIIA_TFIIB_Pol_II_TFIIF_TFIIE_complex_(complex) TFIID_(complex) CDK7 CAK_(complex) CCNH
REACTOME_REACT_16942 Cam-PDE_1_homodimer_(complex) active_Cam-PDE_1_(complex)
REACTOME_REACT_2085 eIF2_subunit_complex_(complex) eIF2B_subunits_complex_(complex) EIF2B4 EIF2B5 EIF2B2 EIF2B3 EIF2B1 eIF2_GDP__eIF2B_(complex) EIF2S1 eIF2_GTP_(complex) EIF2S3 EIF2S2
BIOCYC_PWY-0 ALDH3B2 ALDH3B1 aldehyde_dehydrogenase SAT1 ALDH3A2 ALDH3A1 SAT2 ALDH2 MAOB aldehyde_dehydrogenase__mitochondrial_(complex) ALDH1B1 MAO-B_(complex)
PID_Type_II_Na__Pi_cotransporters Electrogenic_Na+/Pi_cotransporters SLC34A3
REACTOME_REACT_6152 UniProt_P03468_NA UniProt_P03508_NS UniProt_P03428_PB2 UniProt_P0C0U1_PB1 UniProt_P06821_M UniProt_P03452_HA EMBL_J02151_P1_mRNA viral_antigens_(complex) UniProt_P03496_NS UniProt_P03485_M UniProt_P03433_PA UniProt_P03466_NP UniProt_P03431_PB1
REACTOME_REACT_2156 SMUG1 DNA_containing_a_hNTH1-bound_apurinic/apyrimidinic_site_(complex) UNG2_glycosylase_uracil_complex_(complex) hNTH1_glycosylase_thymine_glycol_complex_(complex) MBD4 DNA_containing_a_TDG-bound_apurinic/apyrimidinic_site_(complex) TDG hNTH1_glycosylase__foramidopyrimidine_complex_(complex) DNA_containing_UNG2-bound_apurinic/apyrimidinic_site_(complex) DNA_containing_an_hSMUG1-bound_apurinic/apyrimidinic_site_(complex) DNA_containing_an_MBD4-bound_apurinic/apyrimidinic_site_(complex) NTHL1 CCNO TDG_glycosylase_ethenocytosine_complex_(complex) hNTH1_glycosylase_dihydrouracil_complex_(complex) TDG_glycosylase_thymine_complex_(complex)
REACTOME_REACT_24969 Nuclear_factor_NF-kappa-B_(family) IkBs_NFkB_(complex) NFKBIA IPS-1_TRAF2/TRAF6_(complex) IKBKB IKBKG Activated_IKK_Complex_(complex) dsRNA_RIG-I/MDA5_(complex) MAP3K1 dsRNA_RIG-I/MDA5_IPS-1_TRAF2/TRAF6_(complex) NFKBIB NFKB1 NFKB2 TRAF2 TRAF6 CHUK NF-kappaB_inhibitor_(family) RELA dsRNA_RIG-I/MDA5_IPS-1_TRAF2/TRAF6_MEKK1_(complex) NF-kB_complex_(complex) Phospho-NF-kappaB_Inhibitor_(family) TRAF2_and_TRAF6_(family) MAVS
BIOCYC_PWY-6369 IP6K3 IPMK PPIP5K2 PPIP5K1 IPPK IP6K2 IP6K1
PID_Electric_Transmission_Across_Gap_Junctions Hemi-Connexin_45_Complex_(complex) Connexin_36/Connexin_45_Gap_Junction_Complex_(complex) Connexin_36_Gap_Junction_Complex_(complex) PANX2 Hemi-Connexin_62_Complex_(complex) Connexon36_(complex) GJC1 GJD2 Hemi-Pannexin_2_Complex_(complex) Hemi-Pannexin_1_Complex_(complex) PANX1 GJA10 Pannexin_1/Pannexin_2_Gap_Junction_Complex_(complex) Connexin_62_Gap_Junction_Complex_(complex)
PID_Formation_of_the_active_cofactor__UDP_glucuronate UGDH UDP-glucose_pyrophosphorylase_2_octamer_(complex) UDP-glucuronate_transporter_homohexamer_(complex) SLC35D1 UDP-glucose_dehydrogenase_hexamer_(complex) UGP2
PID_Inhibition_of_the_proteolytic_activity_of_APC_C_required_for_the_onset_of_anaphase_by_mitotic_spindle_checkpoint_components MAD2_CDC20_complex_(complex) MAD2L1 CDC20
REACTOME_REACT_19358 CD28 CD28_bound_to_B7_ligands_(complex) CD80 FYN CD28_B7-2_(complex) CD28_B7-1_(complex) CD86 CD80_(B7-1)_homodimer_(complex) GRAP2 Phospho_CD28_homodimer_(complex) phospho_CD28_B7-1/B7-2_(complex) CD28_Gads_(complex) CD28_homodimer_(complex) LCK LCK__FYN_(family)
PID_Regulation_of_gene_expression_in_endocrine_committed__NEUROG3___progenitor_cells NEUROG3 NKX2-2 PAX4 NEUROD1 INSM1
REACTOME_REACT_1006 PLK1 LIN37 PKMYT1 FOXM1 p-T611_S730_S739-FOXM1_EP300_CDC25A_Gene_(complex) p-T611_S730_S739-FOXM1_MuvB_MYBL2_PLK1_Gene_(complex) MYBL2 LIN9_LIN37_LIN52_LIN54_RBBP4_(complex) p-T611-FOXM1_p-T210-PLK1_(complex) WEE1 p-T611_S730_S739-FOXM1_MuvB_MYBL2_CCNB1_Gene_(complex) CDC25C CENPF CDC25A EP300 CCNB2 CCNB1 LIN9 p-T611_S730_S739-FOXM1_MuvB_MYBL2_CCNB2_Gene_(complex) RBBP4 LIN54 LIN52 p-T611_S730_S739-FOXM1_CENPF_Gene_(complex)
PID_apppathway BACE1 P3 APP Gamma_Secretase_(complex) ADAM10 amyloid-beta PSEN1
BIOCYC_DETOX1-PWY TYRP1 SOD2 SOD3 SOD1 catalase_(complex) CAT superoxide_dismutase_(Cu-Zn)
PID_RNA_Polymerase_I_Chain_Elongation HIST1H4C ERCC2 ERCC3 RNA_Polymerase_I_Holoenzyme_(complex) POLR1A POLR1B POLR1C POLR1D CBX3 RNA_Polymerase_I_promoter_escape_complex_(complex) UBTF Nucleosome_with_Deacetylated_H4_and_H3_Dimethylated_at_Lysine-9_(complex) GTF2H3 GTF2H2 GTF2H1 GTF2H4 Nucleosome_with_H3_dimethylated_at_lysine-9__HP1gamma_Complex_(complex) MNAT1 POLR2H POLR2K TAF1C TAF1B TAF1A SL1_(complex) TFIIH_(complex) Histone_H3_dimethylated_at_lysine-9 CDK7 CAK_(complex) CCNH Acetylated_SL1_(complex)
BIOCYC_PWY-6400 myeloperoxidase_(complex)
PID_Pausing_and_recovery_of_HIV_1_elongation NELFB P-TEFb_complex_(complex) TCEB1 NELFA NELFE TCEB3 CCNT1 Elongin_B_C_complex_(complex) CCNT2 RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) SSRP1 phospho-Spt5 POLR2K CDK9 TCEB2 FACT_complex_(complex) ELL SUPT16H Elongin_Complex_(complex) TCEA1 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L CTDP1 POLR2I POLR2H HIV-1_processive_elongation_complex_(complex) POLR2J GTF2F1 NELFCD GTF2F2 HIV-1_paused_processive_elongation_complex_(complex) NELF_complex_(complex) SUPT4H1 DSIF_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex)
PID_rarpathway RARA RXRA Retinoids RXR/RAR/Retinoid_(complex)
PID_insulin_glucose_pathway v-SNARE STX4 AKT1 INSR STXBP4 INS CALM2 PPP1R3A Exocyst_(complex) TBC1D4 14-3-3_family Insulin_Receptor/Insulin_(complex) ASIP RHOQ PP1-C/PP-1G/Glycogen_(complex) GYS1 TRIP10 PP1-C/PP-1G_(complex) Atypical_PKCs VAMP2 PPP1CC AS160/CaM/Ca2+_(complex) AS160 SLC2A4 AKT2 GSK3B TC10/GTP/CIP4/Exocyst_(complex) SNARE/Synip_(complex) AS160/14-3-3_(complex)
REACTOME_REACT_12555 TAK1/TAB2_complex_bound_to_TRAF6/CBM_complex_(complex) PI3K_(complex) Inhibitor_of_KappaB_kinase_(IKK)_Complex_(complex) NFKBIA PI3K-catalytic_subunit_(family) IKBKB IKBKG Activated_CARMA1_(complex) Active_PKC_theta_bound_to_DAG_(complex) Ub-TRAF6_trimer_bound_to_CBM_complex_(complex) PIK3CA PIK3CB TRAT1 MAP3K7 BCL10 CARMA1_trimer_(complex) IKK_complex_with_phosphorylated_IKK_beta_(complex) PI3K_bound_to_TRAT_(complex) PIK3R2 PIK3R1 NFKB1 RELA PI3K-regulatory_subunit_(family) phosphorylated_TAK1_bound_to_TAB2_(complex) MALT1_trimer_bound_to_Bcl10_and_CARMA1_trimer_(complex) MALT1 TRAF6 CARD11 CHUK CARMA1_bound_to_PDK1_(complex) PRKCQ UBE2V1 Bcl10_trimer_bound_to_CARMA1_trimer_(complex) MALT1_trimer_(complex) PDK1_bound_to_either_PIP3_or_PI(3_4)P2_(complex) Ubc13_UBE2V1_(complex) UBE2N TAB2 Phosphorylated_Bcl10_bound_to_CARMA1_and_RIP2_(complex) NF-kB_complex_(complex) IkB(alpha)_NF-kB_complex_(complex) Bcl10_bound_to_CARMA1_(complex) PDPK1 p-Y90-PKC-theta_DAG_(complex) PKC-theta_(open)__DAG_(complex) TRAF6_trimer_bound_to_CBM_complex_(complex)
PID_sumopathway UBE2I SUMO2/3/SAE1/SAE2_(complex) SUMO2 Sumo_target_protein/SUMO_1_(complex) Sumo_target_protein/SUMO2/3SUMO2/3_(complex) SUMO1 SUMO1/SAE1/SAE2_(complex) SUMO3 SAE1/SAE2_(complex) SAE1 UBA2 SUMO_target_protein Sumo_target_protein/SUMO2/3/SUMO2/3/SUMO2/3_(complex) Sumo_target_protein/SUMO2/3_(complex) SUMO2/3/Ubc9_(complex) Sumo_target_protein/SUMO2/3/SUMO2/3/SUMO2/3/SUMO1_(complex)
REACTOME_REACT_15296 Orc4_Orc5_Orc3_Orc2_origin_(complex) Orc3_Orc2_origin_(complex) ORC6 ORC4 ORC5 ORC2 ORC3 ORC1 Orc5_Orc3_Orc2_origin_(complex) Orc2_origin_(complex) ORC_complex_bound_to_origin_(complex) Orc1_Orc4_Orc5_Orc3_Orc2_origin_(complex)
PID_p27pathway E2F-1/DP-1_(complex) NEDD8 Cyclin_E/CDK2_(complex) SKP2 UBE2M E2F1 SKP1 CDKN1B CCNE1 CKS1B CDK2 SKP2/SKP1/CKS-1/CUL1/Roc1/NEDD8/UBE2M_(complex) RBX1 CUL1 TFDP1
BIOCYC_PWY-6 FPGT FUK
PID_ppargpathway NCOA2 NCOA1 RXR/PPAR-gamma/PGC1-alpha/SRC1/CBP/p300_(complex) PPARGC1A RXRA TIF2/TRAP220/PPAR-gamma/PBP/RXR_(complex) PPARG MED1 EP300 CREBBP
PID_CaM_pathway Active_Calmodulin_(complex) CALM1
BIOCYC_NAD-BIOSYNTHESIS-II NMRK2 ACP6 ACPL2 cytosolic_5prime-nucleotidase_IB NT5E ENPP3 NMRK1 ENPP1 NUDT12 NT5C3B 5prime-NT_(complex) NMNAT2 NMNAT3 NMNAT1 ectonucleotide_pyrophosphatase/phosphodiesterase_E_NPP_phosphodiesterase_I/nucleotide_pyrophosphatase_phosphodiesterase_I_PD//nucleotide_pyrophosphatase
REACTOME_REACT_163932 GNAT1-GTP_PDE6_(complex) Gt-alpha-GTP_(complex) PDE6A CNGB1 MII_(complex) GNB1 RHO Transducin-beta__gamma_(complex) PDE6B CNGA1 CNG_channel_(complex) Phosphodiesterase_6_(complex) PDE6G GNGT1 Transducin-GTP_(complex) GNAT1 N-ACYL-GNAT1_(family)
BIOCYC_PWY66-4 MSMO1 LBR TM7SF2 NSDHL SQLE DHCR7 SC5D EBP LSS CYP51A1 HSD17B7 FDFT1 3-beta-hydroxysteroid-delta<sup>8</sup>-delta<sup>7</sup>-isomerase_(complex) DHCR24
REACTOME_REACT_614 Activated_RAF1_complex_MEK2_(complex) p21_RAS_(family) Activated_RAF1_complex_(complex) HRAS NRAS p21_RAS_GTP_(complex) MAP2K2 MAP2K1 YWHAB Activated_RAF1_complex_MEK1_(complex) RAF1 KRAS
REACTOME_REACT_1941 Active_Pol_II__transcription_complex_with_damaged_DNA_hybrid_(complex) Stalled_Pol_II_complex_with_damaged_DNA_hybrid_(complex) POLR2E POLR2D POLR2G POLR2F POLR2A POLR2C POLR2B POLR2L RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex) POLR2I POLR2H POLR2K POLR2J
PID_Autodegradation_of_Cdh1_by_Cdh1_APC_C phospho-Cdh1_phospho-APC/C_complex_(complex) phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) PSMD9 PSMD8 PSMB10 PSMD5 PSMD11 PSMD7 PSMD6 PSMD1 PSMD3 PSMD2 phospho-Cdh1_phospho-APC/C_(complex) UBE2D1 PSMF1 CDC16 multiubiquitinated_Cdh1_associated_with_APC/C_(complex) ANAPC11 ANAPC10 PSMA2 PSMA3 PSMA1 PSMA6 PSMA7 PSMA4 PSMA5 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 UBE2E1 PSME2 PSME3 PSME1 PSMD14 ANAPC1 ANAPC2 ANAPC5 ANAPC4 ANAPC7 PSMD4 CDC27 CDC26 UBE2C FZR1 CDC23 PSMD10 PSMD13 PSMD12 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 PSMB9 PSMB8 PSMB7 PSMB6 PSMB5 PSMB4 PSMB3 PSMB2 PSMB1
REACTOME_REACT_12621 Tie2_and_Dok-2_complex_(complex) PI3K_(complex) HRAS PI3K-catalytic_subunit_(family) p21_RAS_(family) TEK PIK3CA PIK3CB NRAS DOK2 Tie2/Ang1_dimer_(complex) Complex_of_Tie2_Ang2_(complex) pTie2_and_SHP2_complex_(complex) PIK3R2 PIK3R1 ANGPT2 PI3K-regulatory_subunit_(family) ANGPT4 Tie2_Grb7_complex_(complex) p85_bound_to_Tie2_(complex) SHC1 Tie2_and_Grb14_complex_(complex) Complex_of_Tie2_Ang-1_(complex) pTie2_SHC1_complex_(complex) KRAS ANGPT1 SOS1 Tie2_and_Ang4_complex_(complex) PTPN11 GRB14 pTie2_Ang-1_(complex) p21_RAS_GTP_(complex) SOS-1_bound_to_Tie2_Grb2_(complex) GRB2 Grb2_bound_to_Tie2_(complex) GRB7 Phosphorylated_Tie2_in_Tie2/Akt_dimer_(complex)
PID_Chemokine_receptors_bind_chemokines CCR10_CCL27_28_(complex) CCL5 CCRL1 Chemokine_XC_receptor_1__XC1_ligands_(complex) CCL19_21 CCR6 CCR7 CCL27_28 CCR9 CX3C_receptor_fractalkine_(complex) CXCR2_CXCR2_ligands_(complex) XC1_ligands XCR1 CCR3_4_5 CXCR3 CXCR2 CXCR1 CCR9_CCL25_(complex) CXCR5 CX3CL1 CCL20 CCBP2 CCL25 CXCR6 CCBP2_CCBP2_ligands_(complex) CXCR5_CXCL13_(complex) CCR7_CCL19_21_(complex) CCR10 CXCR3_ligands CXCL13 CXCL12 CXCL16 CCR1_2_8_CCL16_(complex) CCL16 CCBP2_ligands CCL19__CCL21__CCL25 CXCR3_CXCR3_ligands_(complex) CCR3_4_5_CCL5_(complex) CXCR4_7_CXCL12_(complex) CXCR6_CXCL16_(complex) CX3C1_receptor CXCR1_CXCR1_ligands_(complex) CCR11_CCL19_21_25_(complex) CCR6_CCL20_(complex)
PID_Translesion_synthesis_by_Pol_zeta MAD2L2 UniProt_Q9UID5_hREV3 Pol_zeta_complex_(complex) Pol_zeta_damaged_DNA_template_complex_(complex)
PID_Formation_of_a_pool_of_free_40S_subunits RPS13 RPS12 RPS11 RPS10 RPS17 RPS16 RPS15 RPS14 EIF3D RPS19 RPS18 RPS15A RPS7 RPS6 RPS5 eIF3_subunits_complex_(complex) RPS27A RPS2 EMBL_X03205 FAU RPS9 RPS8 EIF3H EIF3I EIF3J EIF3K EIF3A EIF3B EIF3C EIF1AX EIF3E EIF3F EIF3G 40S_eIF3_eIF1A_(complex) RPS26 RPS27 RPS24 RPS25 RPS23 RPS20 RPS21 RPS28 RPS29 RPS4Y1 RPS4X RPSA 40S_ribosomal_complex_(complex) RPS3A RPS3
PID_Interleukin_1_signaling IL1_receptor_complex_(complex) Phospho-MEK1__phospho-SEK1 hp-IRAK1_oligo-TRAF6_(complex) K6_polyubiquitinated_TRAF6_(complex) Inhibitor_of_KappaB_kinase_(IKK)_Complex_(complex) IKBKB Interleukin_1_receptor_type_2_interleukin_1_(complex) hp-IRAK1__p-Pellino-1_2_(3)_(complex) IKBKG NFKB_p105_TPL2_ABIN2_(complex) hp-IRAK1_K6_poly-Ub_oligo-TRAF6_(complex) Activated_IKK_Complex_(complex) IL1B IL1R2 IL1R1 MAP3K8 beta-TrCP_Skp1_Cul1_Rbx1_(complex) Interleukin-1_receptor_type_1_Interleukin-1_(complex) SKP1 MAP3K3 UBE2N hp-IRAK1_TRAF6_(complex) MAP3K7 IL1_IL1R1_IL1RAP_MYD88_homodimer_(complex) IL1_receptor_complex-_activated_IRAK4_TOLLIP_hp-IRAK1_(complex) hp-IRAK1_K6-poly-Ub_oligo-TRAF6_TAK1_complex_(complex) IL1_receptor_complex-_activated_IRAK4_TOLLIP_p-IRAK1_(complex) IRAK2 IRAK3 IRAK1 CUL1 IRAK4 p-Pellino-1_2_(3) TRAF6 SQSTM1 IL1_receptor_complex-activated_IRAK4_TOLLIP_IRAK1_(complex) Pellino_1_2_3 IL1_receptor_complex_TOLLIP_(complex) CHUK IL1R1_IL1_IL1RAP_(complex) TAB2/3 TNIP2 Poly-K6-Ub-hp-IRAK1_(complex) TRAF6-regulated_IKK_activator_1_(complex) IL1_receptor_complex_-_activated_IRAK4_TOLLIP_(complex) p62_MEKK3_TRAF6_(complex) IL1RAP UBE2V1 Interleukin_1_receptors TAK1_TAB1_TAB2/3_(complex) hp-IRAK1_K6-polyUb_TRAF6_(complex) IL1RN MYD88 TOLLIP Interleukin_1_receptors_IL1RN_(complex) Interleukin-1 MYD88_homodimer_(complex) hp-IRAK1__IRAK4 Poly-K6-Ub-hp-IRAK1_IKK_complex_(complex) BTRC NFKB1 MEK1__SEK1 SCF_betaTrCP_complex_p-NFKB_p105_(complex) IL1_receptor_complex-activated_IRAK4_TOLLIP_hp-IRAK_TRAF6_(complex) hp-IRAK1_K6-poly-Ub_oligo-TRAF6_Activated_TAK1_complex_(complex) p62_MEKK3_(complex) RBX1 TAB1 MAP2K6
REACTOME_REACT_25073 3_cytosolic_halocarboxylases_(complex) PCCA ACACA mitochondrial_holocarboxylases_(complex) ACACB PCCB 3-methylcrotonyl-CoA_carboxylase_complex_(complex) 4x(Btn-PC_Mn2+)_(complex) 4x(PC_Mn2+)_(complex) PC biotinylated_propionyl-CoA_carboxylase_dodecamer_(complex) propionyl-CoA_carboxylase_protomer_(complex) Btn-ACACA_2Mn2+_(complex) propionyl-CoA_carboxylase_dodecamer_(complex) MCCC2 MCCC1 Btn-ACACB_2Mn2+_(complex)
PID_Coenzyme_A_biosynthesis PPCDC COASY PANK2 PPCDC_homotrimer_(FMN_cofactor)_(complex) SLC25A16 PPC_synthase_homodimer_(complex) PPCS PANK1;3;4
PANTHER_P00043 Complex_(mAChR2/4/_ACh)_(complex) AC Complex_(VAChT/ACh)_(complex) mAChR2/4 Complex_(CHT1/choline)_(complex) CHT1 PKA VAChT GIRK
REACTOME_REACT_1838 PCNA POLA2 POLA1 DNA_polymerase_alpha_primase_(complex) POLD2 RNA_primer-DNA_primer_origin_duplex_(complex) POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 PCNA_homotrimer_(complex) PRIM2 RNA_primer_origin_duplex_DNA_polymerase_alpha_primase_complex_(complex) POLD4 Processive_complex_(complex) RNA_primer-DNA_primer_origin_duplex_PCNA_(complex) PRIM1
PID_il2rbpathway BCL2L1 CRKL PI3K_(complex) BAD HRAS AKT1 MAP2K1 SOS1 RAF1 IKZF3 SHC1 E2F-1/DP-1_(complex) cyclins STAT5 PIK3CA SHC/GRB2/SOS-1_(complex) RPS6KB1 IL-2/IL-2R-alpha/IL-2R-beta/IL-2R-gamma/JAK1/JAK3_(complex) MAPK3 MAPK1 JAK3 PIK3R1 JAK1 MYC PCNA Nmi/STAT5_(complex) FOS PTPN6 IL2RA IL2RB SOCS1 SOCS3 E2F1 IL2RG IRS1 CBL MAP2K2 GRB2 IL2 TFDP1 NMI PPIA BCL2
REACTOME_REACT_16956 CCT8 CCT2 CCT3 TUBA1A CCT7 CCT4 CCT5 tubulin-GTP_folding_intermediate_(complex) CCT6A CCT/TriC(ATP)_unfolded_tubulin_complex_(complex) CCT/TriC(ADP)-associated_non-native_tubulin_(complex) TUBB6 CCT/TriC(ADP)_(complex) TUBB3 TUBB1 TUBA3C Unfolded_alpha/beta_tubulin_(family) TUBA4A TUBB2A TUBB2B TUBB4B TUBB4A TUBA1C TCP1 TUBA1B
BIOCYC_SALVADEHYPOX-PWY PNP 5prime-NT_(complex) NT5E NT5C3A ADAT3 XDH 5prime_nucleotidase AMP-specific-5prime-NT_(complex) NT5C1A ADA XD_(complex) NT5C2
PID_p53_Independent_DNA_Damage_Response CDC25A
PID_mRNA_Decay_by_3__to_5__Exoribonuclease DCPS DIS3 Exosome_Ring_Hexamer_(complex) EXOSC8 EXOSC9 Exosome_Complex_(complex) EXOSC2 EXOSC3 EXOSC1 EXOSC6 EXOSC7 EXOSC4 EXOSC5
BIOCYC_PWY-6351 PI4KB PI4KA PLCZ1 PLCG2 PLCG1 PI4K2B phosphatidylinositol_4-kinase__type_III__alpha CDIPT PLCH2 PLCH1 PIP4K2A PIP5KL1 PIP4K2C PIP4K2B PLCB1 PLCB3 PLCB4 PLCD4 PLCD3 hypothetical_protein_MGC26597 PIP5K1C PIP5K1B PLCE1 PLC_BETA_PHOSPHOLIPASE_C_BETA
PID_Nicotinamide_salvaging NAPRT1 NAMPT Nicotinate_phosphoribosyltransferase_homodimer_(complex)
REACTOME_REACT_25325 AUF1_Dimer_(isoform_p37_or_p40)_(complex) UBC Ubiquitinated_AUF1_Tetramer__Destabilized_mRNA_Complex_(complex) HSPB1 AUF1_Tetramer__Destabilized_mRNA_Complex_(complex) PABPC1 EIF4G1 AUF1-_and_signal_transduction-regulated_complex_(ASTRC)_(complex) Ubiquitinated_AUF1_Tetramer_(complex) HSPA8 HSPA1B UBA52 Ubiquitinated_AUF1_(isoform_p37_or_p40)_(family) RPS27A UBB AUF1_Tetramer_(isoform_p37_or_p40)_(complex) HNRNPD ubiquitin_(family)
PID_Apoptotic_cleavage_of_cellular_proteins active_caspase-6_(complex) PTK2 CLSPN APC_fragment_(778-2843) BIRC2 Caspase-8_dimer_(complex) active_caspase-7_(complex) MST4 STK24 BMX CASP6 FNTA ACIN1 PRKCD SATB1 PRKCQ active_caspase-3_(complex) BCAP31 CASP7 CASP3 ROCK1 CASP8 APC APC_fragment_(1-777)
PID_IRS_activation Insulin_(complex) activated_insulin_receptor_(complex) IRS phospho-IRS_activated_insulin_receptor_(complex) IRS_activated_insulin_receptor_(complex) INS INSR phospho-insulin_receptor_(complex) phospho-IRS
PID_Transport_of_Mature_mRNA_derived_from_an_Intron_Containing_Transcript NUP88 AAAS TAP_3prime-polyadenylated__capped_mRNA_complex_(complex) NCBP1 NCBP2 Cap_Binding_Complex_(CBC)_(complex) DHX38 SRSF11 Magoh-Y14_complex_(complex) 3prime-polyadenylated__capped_mRNA_complex_(complex) U2AF2 RNPS1 SRSF5 SRSF4 SRSF7 SRSF6 NUP62 NUP133 SRSF3 SRSF2 U2AF1 NUP98 SRSF9 NUP43 NUP188 UniProt_O43831_NFX.1 pre-EJC_complex_(complex) NUP214 NUP210 MAGOH RANBP2 Export_Receptor_bound_mature_mRNA_Complex_(complex) POM121 NXF1 NUP107 NUP93 NUP160 EJC_complex_(complex) ALYREF TPR NUP85 Nup62_Complex_(complex) NUPL1 NUPL2 SRSF1 SEH1L RBM8A Nup107_Complex_(complex) NUP50 NUP54 SRRM1 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 NUP153 UPF3B NUP155 Ceruloplasmin_mRNA CDC40 NUP205 RAE1
PID_Rev_mediated_nuclear_export_of_HIV_1_RNA NUP88 Crm1_Ran_GTPase_GTP_(complex) AAAS Ran_GTPase_GDP_(complex) NUP133 Rev_multimer-bound_HIV-1_mRNA_Crm1_Ran_GTP_NPC_(complex) Rev-bound_HIV-1_mRNA_(complex) Rev NUP85 Rev_multimer-bound_HIV-1_mRNA_CRM1_complex_(complex) XPO1 NUP62 SEH1L EMBL_AF033819_EMBL_AF033819 RAN Ran-GTP_(complex) NUP98 NUP43 NUP188 Ran-GDP_(complex) NUP214 NUP210 RANBP2 POM121 NUP107 Nup107_Complex_(complex) NUP160 NUP93 RANGAP1 TPR Ran_GTP_(complex) Nup62_Complex_(complex) NUPL1 NUPL2 Rev_multimer-bound_HIV-1_mRNA_Crm1_Ran_GTP_(complex) RCC1 NUP50 NUP54 RANBP1 Nuclear_Pore_Complex_(NPC)_(complex) NUP35 NUP37 NUP153 RanBP1_Ran-GTP_CRM1_Rev-bound_mRNA_complex_(complex) Rev_multimer-bound_HIV-1_mRNA_(complex) NUP155 NUP205 RAE1
PID_FGFR4_ligand_binding_and_activation FGFR4_homodimer_bound_to_FGF_(complex) FGFR4_homodimer_(complex) SDC2 Activated_FGFR_complexed_with_phosphorylated_FRS2__GRB2_and_CBL_(complex) CBL Activated_FGFR4_homodimer_(complex) Phospho-FRS2 GRB2 FGFR4
PANTHER_P00057 Casein_Kinase_1 Complex_(Adenomatous_Polyposis_Coli/Axin/_Diversin/Casein_Kinase_1/_Glycogen_Synthase_Kinase-3Beta/PP2A)_(complex) Kremen Casein_Kinase_2 SWI/SNF Histone_deacetylase PP2A Diversin Protein_Kinase_C Complex_(Dishevelled/Beta-Arrestin/_Frodo/Casein_Kinase_2)_(complex) Complex_(TCF/Smad4/_Beta-Catenin)_(complex) Complex_(Adenomatous_Polyposis_Coli/Beta-Catenin/_Glycogen_Synthase_Kinase-3Beta/Axin/_PP2A/Diversin/_Casein_Kinase_1)_(complex) Cadherin Beta-Catenin Complex_(Bcl9/Pygo/_Beta-Catenin/SWI/_SNF/CBP/_TCF/Smad4)_(complex) Complex_(Ebi/Siah-1)_(complex) Complex_(Beta-Arrestin/Dishevelled)_(complex) Complex_(Adenomatous_Polyposis_Coli/Beta-Catenin/_Axin/PP2A)_(complex) betaTrCP Complex_(Adenomatous_Polyposis_Coli/Axin/_Beta-Catenin/PP2A)_(complex) Complex_(Galpha/Phospholipase_C)_(complex) IP3_Gated_Calcium_Channel Beta-Arrestin Complex_(Histone_deacetylase/Transducin-like_Enhance_of_Split_1-3)_(complex) Frodo Complex_(Adenomatous_Polyposis_Coli/Beta-Catenin/_Axin/PP2A/_Diversin/Casein_Kinase_1)_(complex) Bcl9 Wnt TCF Glycogen_Synthase_Kinase-3Beta Pygo Galpha betacatenin Calcineurin Complex_(TCF/Beta-Catenin/_Smad4/Bcl9)_(complex) Complex_(Wnt/Frizzled)_(complex) Complex_(Adenomatous_Polyposis_Coli/Beta-Catenin/_Siah-1/Ebi/_Axin/PP2A)_(complex) Complex_(Dishevelled/Casein_Kinase_2/_Beta-Arrestin/Frodo/_FRAT)_(complex) LRP5/6 Complex_(Axin/PP2A/_Adenomatous_Polyposis_Coli)_(complex) FRAT Complex_(Adenomatous_Polyposis_Coli/Axin/_PP2A/Diversin/_Casein_Kinase_1/Beta-Catenin/_betaTrCP/Glycogen_Synthase_Kinase-3Beta)_(complex) Complex_(Beta-Catenin/TCF/_Smad4/Bcl9/_Pygo/SWI/_SNF)_(complex) Complex_(Adenomatous_Polyposis_Coli/Axin/_PP2A/Beta-Catenin/_Siah-1/Ebi)_(complex) Siah-1 Complex_(Axin/PP2A)_(complex) Complex_(Dickkopf/Kremen)_(complex) Complex_(Bcl9/Beta-Catenin/_TCF/Smad4/_Pygo)_(complex) NFAT Complex_(Dishevelled/Beta-Arrestin/_Frodo)_(complex) Axin Transducin-like_Enhance_of_Split_1-3 Ebi Dishevelled Smad4 CBP Complex_(Beta-Catenin/Cadherin)_(complex) Nemo-like_Kinase Complex_(Frizzled/Wnt/_LRP5/6)_(complex) Complex_(TCF/Smad4)_(complex) Dickkopf Phospholipase_C Frizzled Complex_(Adenomatous_Polyposis_Coli/Axin/_Diversin/Beta-Catenin/_PP2A)_(complex)
PID_CD28_dependent_PI3K_Akt_signaling Phospho_CD28_homodimer_(complex) TRIB3 PIP3_PDK1_Phospho-AKT_(complex) RICTOR MAP3K8 THEM4 PIK3CA PI3K_alpha_(complex) CD28_PI3K_(complex) CD86 PIK3R1 CD28 TORC2_complex_(complex) PDK1_AKT_(complex) MTOR PDK1_AKT_PIP3_(complex) Akt_pCot_pNIK_(complex) MLST8 Lck/Fyn PIP3_PDK1_active_AKT_(complex) Akt_pCot_(complex) phospho_CD28_B7-1/B7-2_(complex) SIN1 MAP3K14 PDPK1
PID_Phosphorylation_of_CD3_and_TCR_zeta_chains CD3_epsilon__CD3_gamma_with_phosphorylated_ITAM_(complex) Antigen-bearing_MHC_Class_II__TCR_with_phosphorylated_ITAMs_CD4_(complex) PAG1 CD3_epsilon_delta_(complex) TCR_chain_beta CD4 CD247 CD3_zeta_dimer_with_phosphorylated_ITAMs_(complex) CD3_epsilon__CD3_delta_with_phosphorylated_ITAMs_(complex) TCR_chain_alpha T-cell_receptor_(complex) CSK MHC_Class_II_bearing_antigen_peptide_(complex) CD3_epsilon_gamma_(complex) Antigen-bearing_MHC_Class_II___TCR_complex_CD4_p-Lck(Y505)_(complex) Antigen-bearing_MHC_Class_II___TCR_complex_CD4_Lck_(complex) Antigen-bearing_MHC_Class_II__TCR_complex_CD4__Lck_phosphorylated_at_Tyr394_(complex) Csk_p-PAG_(complex) CD3E T-cell_receptor_complex_(complex) T-cell_receptor_complex_with_phosphorylated_ITAMs_(complex) PTPRC CD3D LCK CD3G
PANTHER_P00001 VAT2 VAT1 Complex_(NET/norepinephrine)_(complex) amine_translocator Complex_(VAT1/epinephrine)_(complex) Complex_(DAT/dopamine)_(complex) DAT Complex_(VAT2/DOPA)_(complex) Complex_(VAT1/norepinephrine)_(complex) Complex_(amine_translocator/epinephrine)_(complex) NET
PID_Loss_of_proteins_required_for_interphase_microtubule_organization_from_the_centrosome CEP250
PID_mapkpathway RAF1/A-RAF/B-RAF ASK1/TAK1/MAP3K11 MEF2 HRAS IKBKB MAP2K2 MAP2K7 MAP2K6 MAP2K5 MAP2K4 GCK/MAP4K3/MAP4K4 MAPK14 MEK3/MEK6 MAPK11/ERK6/MAPK13/p38 CEBPA STAT1 MAP3K1 JUN MAP3K7 ERK1/ERK2 ELK1 MAPK7 MYC MEK1/MEK2 MAP4K5/MAP4K1 FOS SP1 CHUK CREB1 MKK7/MEK4 MAP2K3 p38_Target_Kinases MAP3K4/MAP3K12 JNK1/MAPK9/MAPK10 MAP3K2/MEKK1/MAP3K3/MAP3K8 MAX RPS6KA1 MAP3K13 MAP3K14 RAC1 ATF2 PAK1 PAK2 ERK_Target_Kinases
PID_carm1pathway RARA NCOA3 Retinoids p300/CBP_(complex) PRKACB CARM1 CREB1 RXRA PRKAR2A PKA_(complex) PRKACG PRKAR2B PRKAR1A PRKAR1B CBP/p300/CREB_(complex) RXR/RAR/Retinoid_(complex) EP300 CREBBP CBP/p300/ACTR/RXR/CARM1/RAR/retinoids_(complex)
PID_Influenza_Virus_Induced_Apoptosis UniProt_P03468_NA PB1-F2__ANT_3_Complex_(complex) UniProt_P0C0U1_PB1 SLC25A6 TGFB1
PID_Regulation_of_activated_PAK_2p34_by_proteasome_mediated_degradation PSMD9 PSMD8 PSMB10 PSMD5 PSMD4 PSMD7 PSMD6 PSMD1 PSMD3 PSMD2 PSMF1 ubiquitinated_PAK-2p34_(complex) PSMA2 PSMA3 PSMA1 PSMA6 PSMA7 PSMA4 PSMA5 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSME2 PSME3 PSME1 PSMD14 PSMD11 PSMD10 PSMD13 PSMD12 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 PAK2 PSMB9 PSMB8 PSMB7 PSMB6 PSMB5 PSMB4 PSMB3 PSMB2 PSMB1
BIOCYC_PWY-6124 PAICS ADSL ATIC
PID_Vitamin_B1__thiamin__metabolism TPK1 SLC19A2;_SLC19A3 TPK1_homodimer_(Mg2+)_(complex)
PID_Orc1_removal_from_chromatin PSMD9 PSMD8 Orc2_associated_with_MCM8_(complex) PSMD5 PSMD4 PSMD7 PSMD6 PSMD1 PSMD3 PSMD2 CDC6 PSMF1 PSMA3 PSMB10 CDT1 Cyclin_A_phospho-Cdk2(Thr160)_complex_(complex) PSMA2 Cyclin_A_Cdk1_substrate_proteins PSMA1 PSMA6 PSMA7 PSMA4 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 pre-replicative_complex_(Orc1-minus)_(complex) ORC6 PSME2 ORC4 ORC5 ORC2 ORC3 ORC1 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2 Mcm2-7_complex_(complex) PSME1 Cyclin_A_Cdk2_substrate_complex_(complex) MCM8 PSMD14 PSME3 PSMD11 PSMD10 PSMD13 PSMD12 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 CDK2 PSMB9 PSMB8 PSMB6 PSMB5 PSMB4 PSMB3 PSMB2 ubiquitinated_Orc1_(complex)
PID_Cell_death_signalling_via_NRAGE__NRIF_and_NADE mature_beta-NGF_homodimer_(complex) MAPK8 mature_NGF_homodimer_p75NTR_(complex) NGF NGFR
PID_bmppathway BMP2-4/NOG_(complex) SMAD9 SMAD4 SMAD1/SKI_(complex) SMAD6 SMAD1 SMAD5/SKI_(complex) XIAP FST SMAD5 SKI SMURF1 PPM1A MAP3K7 MAPK1 TAK1/TAB_family_(complex) BMP2-4/BMPR2/BMPR1A-1B/RGM/XIAP_(complex) BMP2-4/CHRDL1_(complex) SMAD1/SMURF2_(complex) TAB_family BMP7/BMPR2/BMPR1A-1B_(complex) SMAD1/SMAD1/SMAD4_(complex) SMAD6-7/SMURF1/SMAD1_(complex) SMAD8A/SMAD8A/SMAD4_(complex) BMP6/BMPR2/BMPR1A-1B_(complex) CHRDL1 SMAD6/SMURF1/SMAD5_(complex) BMPR1A-1B NUP214 BAMBI BMP2-4 BMPR1A-1B-active RGM_family TAK1/SMAD6_(complex) BMP7 BMP6 SOSTDC1 SCP1-3 NOG GSK3B SMAD6-7 BMP2-4/BMPR2/BMPR1A-1B/RGM_(complex) BMPR2 BMP2-4/BMPR2/BMPR1A-1B/RGM/FS_(complex) BMPR1A-1B/BAMBI_(complex) BMP2-4/USAG1_(complex) SMAD5/SMAD5/SMAD4_(complex)
PID_Minus_strand_DNA_synthesis minus_sssDNA_primer_transferred_to_3prime-_end_of_viral_RNA_template_(complex) Matrix p51_subunit_of_RT Reverse_Transcriptase_heterodimer_(complex) Rev nicked_minus_sssDNA_RNA_template_tRNA_primer_(complex) RTC_with_minus_sssDNA_transferred_to_3prime-end_of_viral_RNA_template_(complex) RTC_with_tRNA_primer_RNA_template_(complex) Vpr_protein EMBL_AF033819_EMBL_AF033819 RTC_with_minus_strand_DNA_synthesis_initiated_from_3prime-end_(complex) RNA_template_tRNA_primer_(complex) RTC_with_degraded_RNA_template_and_minus_sssDNA_(complex) minus_sssDNA_RNA_template_tRNA_primer_(complex) RTC_with_extending_minus_strand_DNA_(complex) Vpu_protein RTC_with_nicked_minus_sssDNA_tRNA_primer_RNA_template_(complex) Integrase minus_sssDNA_primer_for_minus_strand_DNA_extension_(complex) VIF p6_protein RTC_with_minus_sssDNA_tRNA_primer_RNA_template_(complex) p66_subunit_of_RT RTC_with_extensive_RNase-H_digestion_(complex) minus_sssDNA_tRNA_primer_generated_by_RNAse-H_(complex) PPIA
PID_GPVI_mediated_activation_cascade PIP3_PDK1_AKT_p(T410)-PKC_zeta_(complex) GPVI_phosphorylated_Fc_Epsilon_R1_gamma_FYN_LYN_Collagen_I_SYK_(complex) FYN p-SLP-76_VAV_(complex) FceRI_gamma_dimer_(complex) AKT1 GPVI_FceRI_gamma_FYN_LYN_(complex) FCER1G PIP3_PDK1_AKT_PKC_zeta_(complex) PIK3CB GPVI_phosphorylated_Fc_Epsilon_R1_gamma_FYN_LYN_Collagen_I_(complex) Vav_PIP2_(complex) PIK3R1 GP6 Vav_family GP_VI___phosphorylated_Fc_Epsilon_R1_gamma_complex_(complex) GPVI_FceRI_gamma_FYN_LYN_Collagen_I_(complex) PDK1_AKT_(complex) PRKCZ PDK1_AKT_PIP3_(complex) GP_VI___FceRI_gamma_dimer_(complex) LCP2 VAV LYN PLCG2 SYK PI3K_beta_(complex) Vav_PIP3_(complex) PDPK1 GPVI_phosphorylated_Fc_Epsilon_R1_gamma_FYN_LYN_(complex)
REACTOME_REACT_22365 L1_trans-homodimer_(complex) Ribosomal_protein_S6_kinase_(family) L1_NUMB_CRMP-2_alpha-adaptin_(complex) MSN pL1_ERM_F-actin_(complex) CLTA L1CAM AP2B1 SH3GL2 AP2S1 L1_AP-2_Clathrin_complex_(complex) KIF4_dimer_(complex) Clathrin-coated_vesicle_(complex) KIF4A AP2M1 pL1_(S1152)_p90rsk_clathrin-dynamin_complex_(complex) MAPK1 ERM_PIP2_(complex) DPYSL2 L1_clathrin-coated_vesicle_(complex) RDX RPS6KA3 AP2A1 NUMB AP2A2 KIF4B_(family) Adaptor_protein_2_complex_(complex) AP2_clathrin_L1_KIF4_microtubule_(complex) RPS6KA1 RPS6KA2 KIAA1598 RPS6KA4 RPS6KA5 RPS6KA6 ERM_(family) pL1_Shootin-1_F-actin_(complex) pL1_(S1204__1248)_ERK2_clathrin-dynamin_complex_(complex) EZR Clathrin_(complex) CRMP-2_NUMB_alpha_adaptin_(complex) Adaptor_protein_complex_2_(AP-2)_large_adaptins_(family) pL1_Ezrin_(complex)
REACTOME_REACT_1405 SMUG1 DNA_containing_a_hNTH1-bound_apurinic/apyrimidinic_site_(complex) hNTH1_glycosylase_thymine_glycol_complex_(complex) MBD4 DNA_containing_a_TDG-bound_apurinic/apyrimidinic_site_(complex) TDG MBD4_glycosylase_thymine_complex_(complex) DNA_containing_UNG2-bound_apurinic/apyrimidinic_site_(complex) DNA_containing_an_hSMUG1-bound_apurinic/apyrimidinic_site_(complex) hNTH1_glycosylase_cytosine_glycol_complex_(complex) TDG_glycosylase_uracil_complex_(complex) DNA_containing_an_MBD4-bound_apurinic/apyrimidinic_site_(complex) NTHL1 CCNO
BIOCYC_PWY-6608 purine_5prime-NT_(complex) GAH_(complex) PNP XDH GDA XD_(complex) NT5C2
PID_Fanconi_Anemia_pathway BRCA1 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 BRCA2 ub-FANCD-_and__ub-FANCI-bound_chromatin_(complex) FANCD2 FAAP100 FANCL PALB2 FANCG FANCF FANCE BRCA1_BRCA2_PALB2_(complex) FANCC FANCB FANCA mono-ubiquitinated_FANCD2_(complex) mono-ubiquitinated_FANCI_(complex) FANCM FA_core_complex_(complex) FAAP24 FANCI
PID_dbpbpathway F2 dbpB/RNA_strand_(complex) Tyrosine_Phosphatase dbpB_20kD RNA_strand dbpB_30kD YBX1
REACTOME_REACT_9491 UniProt_P03468_NA UniProt_P03508_NS UniProt_P03428_PB2 UniProt_P0C0U1_PB1 UniProt_P06821_M UniProt_P03452_HA EMBL_J02151_P1_mRNA viral_antigens_(complex) UniProt_P03496_NS UniProt_P03485_M UniProt_P03433_PA UniProt_P03466_NP UniProt_P03431_PB1
REACTOME_REACT_1628 ERCC8 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex) Stalled_Pol_II_complex_with_damaged_DNA_hybrid_(complex) ERCC1_XPF_complex_(complex) Transcription-coupled_(TC)_repair_complex_(complex) GTF2H3 GTF2H2 GTF2H1 GTF2H4 POLR2E POLR2D POLR2G POLR2F POLR2A POLR2C POLR2B POLR2L MNAT1 TCEA1 POLR2I POLR2H POLR2K POLR2J Active_Pol_II__transcription_complex_with_damaged_DNA_hybrid_(complex) TFIIH_(complex) CDK7 CAK_(complex) CCNH XAB2
PID_Signaling_by_Robo_receptor Glypican-1_HSPG_(complex) RAC1 ROBO1 RAC1-GDP_(complex) Ena/VASP_proteins Slit2_Glypican-1_(complex) GPC1 SLIT2 Glypican-1_Slit2_Robo1_Ena/Vasp_Profilin_(complex) RAC1-GTP_(complex) Glypican-1_Slit2_Robo1_Ena/Vasp_proteins_(complex) Robo1_Slit2_Glypican-1_(complex)
BIOCYC_LYSINE-DEG1-PWY AASS aminoadipic_semialdehyde_synthase_(complex) SCCPDH ALDH7A1
PID_Transport_of_gamma_carboxylated_protein_precursors_from_the_endoplasmic_reticulum_to_the_Golgi_apparatus pro-factor_X_(complex) F2 PROZ pro-protein_C_(complex) F7 F9 PROS1 F10 PROC GAS6
BIOCYC_PWY-5525 CRYL1 DCXR
REACTOME_REACT_756 RPC7/RPC7-like_(family) RNA_Polymerase_III_Holoenzyme_(complex) POLR3F POLR3G POLR3D POLR3E POLR1D POLR3C HsRPC4_HsRPC5_(complex) POLR3A POLR3K POLR3H Elongating_RNA_Polymerase_III_Transcription_Complex_(complex) LZTS1 POLR3GL POLR2E POLR2F POLR2L POLR2H POLR2K HsRPC6_HsRPC3_HsRPC7_(complex) HsRPC8_HsRPC9_(complex) POLR1C POLR3B
REACTOME_REACT_13655 FOXO1
PID_G_alpha__z__signalling_events G-protein_alpha_(z)_GDP_(complex) Heterotrimeric_G-protein_Gz_(active)_(complex) GNAS GNB1 Ligand_GPCR_complexes_that_activate_Gz_Heterotrimeric_G-protein_Gz_(inactive)_(complex) Heterotrimeric_G-protein_Gz_(inactive)_(complex) G-protein_alpha_(i) G-protein_beta-gamma_complex_(complex) G-protein_alpha_(i)__GTP_(complex) Ligand_GPCR_complexes_that_activate_Gz_Heterotrimeric_G-protein_Gz_(active)_(complex) Adenylate_cyclase G-protein_alpha_(s)_GTP_(complex) GNG2 G-protein_alpha_(z)_GTP_(complex) Gs-activated_adenylate_cyclase_(complex) G-protein_alpha_(z)_pS27_GTP_(complex) GNAZ Adenylate_cyclase_(Mg2+_cofactor)_(complex) G-protein_alpha_(z)_GTP_Adenylate_cyclase_(complex) G-protein_alpha_(i)_GTP_Adenylate_cyclase_(complex)
REACTOME_REACT_6743 TSC1_TSC2_(complex) TSC1_Inhibited_TSC2-1-P_(complex) TSC2 TSC1
BIOCYC_PWY66-373 fructose-bisphosphate_aldolase_B_(complex) ketohexokinase_(complex) TPI1 fructose-bisphosphate_aldolase_A_(complex) SI KHK TIM_(complex) ALDOA GALM ALDOC ALDOB sucrase_isomaltase_intestinal//sucrase//isomaltase fructose-bisphosphate_aldolase_C_(complex)
Pathway_7e78c5bc2f3685293121683f791b264f.owl NAT2 NAT1
PID_Alpha_oxidation_of_phytanate HACL1_tetramer_(complex) HACL1 phytanoyl-CoA_dioxygenase_iron_complex_(complex) HACL1_holoenzyme_monomer_(complex) SLC25A17 PHYH SLC27A2
REACTOME_REACT_20537 LAMA3 Laminin-332_(complex) ITGB4 Integrin_alpha6_beta4_Plectin_BP180_complex_(complex) Integrin_alpha6beta4_(complex) DST ITGA6 Integrin_alpha_6_beta_4_Plectin_BP180_Laminin-322_complex_(complex) CD151 Integrin_alpha_6_beta_4_Plectin_complex_(complex) CD151_BP230_BP180_Plectin_Integrin_alpha_6_beta_4__Laminin_(complex) Type_II_hemidesmosome_(complex) LAMC2 PLEC LAMB3 BP230_BP180_Plectin_integrin_alpha_6_beta_4_Laminin_332_(complex) COL17A1
PID_cacampathway CaMKI CAMKII/CaM/Ca_++/CaM/Ca_++_(complex) CamKIV/CaM/Ca_++_(complex) CaMKI/CaM/Ca_++_(complex) CaMKK CAMKII_(8)_(complex) CREB1 CAMK4 CAMKII CaM/Ca_++_(complex) CaM CaMKK/CaM/Ca_++_(complex) CAMKII/CaM/Ca_++/CaM/Ca_++/CaM/Ca_++/CaM/Ca_++_(complex)
PID_cblpathway SRC END GRB2 EGFR EGF_R/SRC/EGF_(complex) SH3KBP1 PKC EGF/EGF-R_(complex) CBL EGF/EGF_R/ubiquitin_(cytoplasm)_(complex) EGF ubiquitin
REACTOME_REACT_1776 PPAT phosphoribosyl_pyrophosphate_amidotransferase_tetramer_(complex) ATASE-(4Fe-4S)-(PRPP-Glutamine)_reactive_complex_(complex)
PANTHER_P04373 5HT1_Receptor GAPDH PKA K+_channel Complex_(GDP/G-protein/_5HT1_Receptor_/5HT+)_(complex) G-protein Complex_(5HT1_Receptor_/5HT+)_(complex)
PID_Peroxisomal_lipid_metabolism CRAT Peroxisomal_multifunctional_enzyme_type_2_dimer_(complex) HSD17B4 ACOT8
BIOCYC_PWY-6364 OCRL INPP5A INPP5B IPMK INPP5D INPPL1 INPP5J INPP5K ITPKA PTEN ITPKC ITPKB SYNJ1 SYNJ2 MINPP1
PID_SLBP_Dependent_Processing_of_Replication_Dependent_Histone_Pre_mRNAs Cap_Binding_Complex_(CBC)_(complex) SLBP Capped_Intronless_Histone_pre-mRNA_CBP80_CBP20_SLBP_ZFP100_Complex_(complex) NCBP1 NCBP2 Capped_Intronless_Histone_pre-mRNA_CBC_complex_(complex) U7_snRNP-specific_Sm_core_complex_(complex) SNRPF U7_snRNP_ZFP100_Complex_(complex) LSM10 LSM11 SNRPB SNRPD3 ZNF473 Capped_Intronless_Histone_pre-mRNA_CBP80_CBP20_SLBP_(complex) SNRPG SNRPE
PID_hnf3pathway FOXA1 FOXA3 FOXA2
BIOCYC_PWY66-161 STEROID_21_HYDROXYLASE_P450 CYP2G1P ACSS3 ACSS2 ACSS1 ALDH2 ALDH3A2 cytochrome_p450 CYP2E1 CYTOCHROME_P450_2 ALDH-E2_(complex)
PID_telpathway TNKS TERT(+1)/hTR_RNA/KU/TRF1_(complex) AKT1 XRCC5 XRCC6 RB1 MYC TERT TEP1 hTR_RNA PRKCA TERT_transcription_factors p53/RB_(complex) POLR2A KRAS TERT(+)/TEP1/hTR_RNA_(complex) E6 TP53 TERT(+1)/TEP1/hTR_RNA_(complex) TERF1 PPP2R5D BCL2
PID_Polymerase_switching_on_the_C_strand_of_the_telomere PCNA RFC_Heteropentamer_(complex) RFC5 Processive_complex_loaded_on_telomere_(complex) RFC1 POLD2 RFC3 RFC2 POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 PCNA_homotrimer_(complex) RFC_Heteropentamer_RNA_primer-DNA_primer_G-strand_extended_telomere_end_(complex) RFC4 RNA_primer-DNA_primer_G-strand_extended_telomere_PCNA_(complex) POLD4
PANTHER_P00017 PCNA Complex_(PCNA/RFC/_Pol_delta)_(complex) RPA Pol_alpha Top EGFR dsDNA-replication_complex_(complex) dsDNA-primase-RFC_complex_(complex) RFC Primase dsDNA_(complex) Hel Histones Complex_(Pol_alpha/Primase)_(complex) dsDNA-primase_complex_(complex)
REACTOME_REACT_25218 HuR_with_phosphoserine221_and_phosphoserine158_mRNA_Complex_(complex) TNFSF13 HuR_with_Unknown_Phosphorylation__mRNA_Complex_(complex) SET HuR_APRIL_pp32_SET/SETalpha_Nup214/SETbeta_CRM1_Complex_(complex) ELAVL1 XPO1 HuR_with_phosphoserine221_and_phosphoserine318_mRNA_Complex_(complex) ANP32A NUP214 HuR_mRNA_Complex_(complex) HuR_mRNA_Complexes_(complex)
BIOCYC_PWY-6307 DOPA_decarboxylase_(complex) ALDH3A2 MAOB AKR1A1 DDC MAO-B_(complex)
PID_c_src_mediated_regulation_of_Cx43_function_and_closure_of_gap_junctions Cx43_ZO-1_hemi-channel_(complex) Cx43_ZO-1_c-src_gap_junction_(complex) closed_Cx43_junctional_channel_(complex) phospho-Y265_Cx43_ZO-1_c-src_hemi-channel_(complex) c-src_associated_cx43_hemi-channel_(complex) GJA1 Connexin_43_connexon_in_Golgi_transport_vesicle_(complex) phospho-Y265_Cx43_ZO-1_gap_junction_(complex) Cx43_ZO-1_(complex) SRC Cx43_ZO-1_c-src_hemi-channel_(complex)
PID_Ketone_body_metabolism D-beta-hydroxybutyrate_dehydrogenase_tetramer_(complex) BDH1
PID_tcrjnkpathway MAP4K1 MAP3K8 PRKCB DBNL LAT/GRAP2/SLP76/HPK1/HIP-55/CRK_family_(complex) CRK_(family) MAP3K1 JUN MAP3K7 LAT/GRAP2/SLP76/HPK1/HIP-55_(complex) GRAP2 MAP2K4 LAT LCP2 MAPK8
PID_APC_C_Cdh1_mediated_degradation_of_Cdc20_and_other_APC_C_Cdh1_targeted_proteins_in_late_mitosis_early_G1 phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) PSMD9 PSMD8 PSMB10 PSMD5 PSMD11 PSMD7 PSMD6 PSMD1 PSMD3 PSMD2 UBE2D1 PSMF1 CDC16 (APC/C_Cdh1)-targeted_cell_cycle_proteins phospho-APC/C_Cdh1_complex_(complex) ANAPC11 ANAPC10 PSMA2 PSMA3 PSMA1 PSMA6 PSMA7 PSMA4 PSMA5 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 UBE2E1 PSME2 PSME3 PSME1 PSMD14 cell_cycle_proteins_phospho-APC/C_Cdh1_complex_(complex) ANAPC1 ANAPC2 ANAPC5 ANAPC4 ANAPC7 PSMD4 multiubiquitinated_cell_cycle_protein_APC/C_Cdh1_complex_(complex) CDC27 CDC26 UBE2C FZR1 CDC23 PSMD10 PSMD13 PSMD12 UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 PSMB9 PSMB8 PSMB7 PSMB6 PSMB5 PSMB4 PSMB3 PSMB2 PSMB1
BIOCYC_PWY-6158 CKB CKM M-B_(complex) CKMT1B CKMT2 ubiquitous_mitochondrial_creatine_kinase_octamer_(complex) sMI-CK_(complex) M-M_(complex) brain_creatine_kinase_(complex)
REACTOME_REACT_23824 GIP
PID_SMAC_binds_to_IAPs_ CASP7 active_caspase-3_(complex) CASP3 SMAC_XIAP_Caspase-3_(complex) SMAC_XIAP_Caspase-9_(complex) active_caspase-7_(complex) XIAP_Caspase-9_(complex) CASP9 XIAP_Caspase-3_(complex) XIAP DIABLO Cleaved_Caspase-9_(complex) SMAC_XIAP_Caspase-7_(complex) XIAP_Caspase-7_(complex)
PID_Packaging_Of_Telomere_Ends HIST1H4D TINF2 ACD Shelterin_Complex_(complex) POT1 Extended_And_Processed_Telomere_End_(complex) TERF2 Extended_And_Processed_Telomere_End_Folded_Into_Higher_Order_Structure_(complex) TERF1 TERF2IP Nucleosome_(complex) Extended_And_Processed_Telomere_End_and_Associated_DNA_Binding_and_Packaging_Protein_Complex_(complex) HIST3H3 Extended_And_Processed_Telomere_End_and_Associated_DNA_Binding_and_Packaging_Protein_Complex_Folded_Into_Higher_Order_Structure_(complex)
PID_P2Y_receptors GPR17 P2RY6_UDP_(complex) P2RY4_UTP_(complex) GPR17_UDP_(complex) P2RY5_LPA_(complex) P2RY14 P2RY10 P2RY11 P2RY12 P2RY13 P2RY10_LPA_(complex) P2RY11__ATP_(complex) P2RY2 P2RY9_LPA_(complex) P2RY1 P2RY6 P2RY4 P2RY12_ADP_(complex) P2RY1_ADP_(complex) P2RY2_ATP_(complex) P2RY14_UDP-glucose_(complex) LPAR6 P2RY13_ADP_(complex) LPAR4
REACTOME_REACT_111174 Particulate_Ag_DC_receptors_(complex)
BIOCYC_PWY-6368 OCRL INPP5B MTMR14 INPP5D INPP5E INPP5F PMPCA TPTE2 INPP5J INPP5K INPP4B INPP4A PTEN TMEM55B SYNJ1 SACM1L INPPL1 TMEM55A MTMR3 PTPMT1 SYNJ2
REACTOME_REACT_486 gamma-H2AX_NBS1_complex_at_the_site_of_double-strand_break_(complex) H2AFX NBN
BIOCYC_PWY-5659 GMPPB GPI GMPPA MPI PMM2 PMM1
REACTOME_REACT_15451 PPP2R1A DYNLL1 SDCCAG8 PLK1 CEP57 cNAP-1_depleted_centrosome_(complex) PLK4 CETN2 NDE1 PRKAR2B DCTN2 DCTN3 CEP135 CENPJ CEP164 DCTN1 NEDD1 TUBA1A DYNC1I2 HAUS2 ALMS1 CSNK1D AZI1 PCM1 PRKACA OFD1 MAPRE1 NINL TUBB ODF2 CEP72 CLASP1 SSNA1 CEP63 YWHAG CEP41 CEP192 FGFR1OP PCNT CCP110 DYNC1H1 TUBA4A PAFAH1B1 CEP152 SFI1 TUBB4A AKAP9 CEP290 TUBG1 CDK1 CEP76 CEP70 ACTR1A TUBB4B CDK5RAP2 HSP90AA1 YWHAE CEP78 CSNK1E CKAP5
PID_pi3kcibpathway PI3K_Class_IB_family_(complex) MAP2K1 MAPK1 PI3K_Class_IB/PDE3B_(complex) PDE3B
REACTOME_REACT_18307 Ca_impermeable_AMPA_receptors_(complex) AP2S1 AP2A_(family) GRIP1/GRIP2_(family) PICK1 AP2M1 AP2A1 AP-2_Complex_(complex) AP2A2 GRIP1 GRIP2 AP2B1
PID_Glutathione_synthesis GSS GCLM gamma-glutamylcysteine_synthase_(complex) GCLC Glutathione_synthase_homodimer_(complex)
PID_Recycling_pathway_of_L1 L1_trans-homodimer_(complex) L1_NUMB_CRMP-2_alpha-adaptin_(complex) pL1_ERM_F-actin_(complex) CLTA CLTC L1CAM p90rsk AP2B1 SH3GL2 AP2S1 L1_AP-2_Clathrin_complex_(complex) Clathrin-coated_vesicle_(complex) AP2M1 MAPK1 ERM_PIP2_(complex) KIF4_homodimer_(complex) SRC DPYSL2 KIF4 L1_clathrin-coated_vesicle_(complex) NUMB Adaptor_protein_2_complex_(complex) AP2_clathrin_L1_KIF4_microtubule_(complex) KIAA1598 Adaptor_protein_complex_2_(AP-2)_large_adaptins EZR Clathrin_(complex) CRMP-2_NUMB_alpha_adaptin_(complex) pL1_Shootin-1_F-actin_(complex) pL1_Ezrin_(complex)
REACTOME_REACT_150320 PTGS2 PTGS1 PGHS2_dimer_(complex) Ac-PTGS1_dimer_(complex) PTGS2_celecoxib_(complex) Ac-PTGS2_dimer_(complex)
PID_Inhibition_of_HSL AKT2 PIP3_Phosphorylated_PKB_complex_(complex) PDE3B
PID_Signaling_by_Insulin_receptor insulin_insulin_receptor_(complex) Insulin_(complex) activated_insulin_receptor_(complex) Insulin_receptor_(complex) INS INSR phospho-insulin_receptor_(complex)
PID_Retrograde_neurotrophin_signalling DNAL4 AP2S1 CLTC Activated_TrkA_receptor_complex_Clathrin-coated_vesicle_(complex) Clathrin-coated_vesicle_(complex) Activated_TrkA_receptor_complex_Clathrin-coated_vesicle_dynein_dynactin_complex_(complex) NGF Activated_TrkA_receptor_complex_(complex) Adaptor_protein_complex_2_(AP-2)_large_adaptins AP2M1 Clathrin_(complex) CLTA Activated_TrkA_receptor_complex_Clathrin-coated_vesicle_Endophilin_(complex) NTRK1 DNM1 Adaptor_protein_2_complex_(complex) beta-NGF_homodimer_(complex) AP2B1 SH3GL2
PID_achpathway MUSK FKHRL1/14-3-3_(complex) PTK2 PIK3R1 SRC CHRNB1 PI3K_(complex) FOXO3 PTK2B RAPSN AGRN AKT1 BAD CHRNG MUSK/RAPSYN/SRC/RAPSYN/SRC/ACH_Receptor_gamma_polypeptide/ACH_Receptor_beta_polypeptide_1/agrin_(complex) PIK3CA PDPK1 TERT YWHAH
PID_Agmatine_biosynthesis ADC AGMAT
REACTOME_REACT_115810 ceramide_CERT_(complex) PPM1L COL4A3BP PPM1L_VAPA/B_dimer_(complex) CERT_PPM1L_VAPA/B_trimer_(complex) VAPB VAPA multiphospho-CERT_PPM1L_VAPA/B_trimer_(complex) ceramide_CERT_PPM1L_VAPA/B_trimer_(complex) VAMP-associated_proteins_A__B_(family)
PANTHER_P06217 DL SCW_(complex) SPZ_dimer/_TL_dimer/_MyD88/TUB/_PLL_(complex) DIF_dimer_phosphoCACT_UBI_SLMB_(complex) DIF PUT_(complex) TGFbetaR_I_(complex) TL_(complex) SAX_(complex) SPZ_(complex) CCK TGFbetaR_II EA/SPN27A_(complex) TKV DL_dimer_CACT_(complex) FYN SLMB DIF_dimer_phospho_CACT_(complex) SPZ_dimer/_TL_dimer/_MyD88/TUB_(complex) SPZ_dimer/TL_(complex) HLA-A CACT SPN27A_SPE_(complex) HV107_HUMAN DL/DIF_dimer_phosphoCACT_UBI_SLMB_(complex) EA activinbeta_full_length DPP_(complex) SPN27A MyD88 _ DL_dimer_phosphoCACT_(complex) DIF_dimer_CACT_(complex) Full-length_BMP_orthologous_ligand MyD88/TUB_(complex) SMOX_(complex) DL_dimer_phosphoCACT_SLMB_(complex) DIF_dimer/CACT_SLMB_(complex) HLA-DOA TUB DIF_dimer_phospho_UBI_CACT_(complex)
BIOCYC_PWY-3561 PCYT1A PLD4 PLD6 PCYT1B PLD1 PLD2 PLD3 CEPT1 CHPT1
PID_L13a_mediated_translational_silencing_of_Ceruloplasmin_expression RPS13 RPS12 RPS11 RPS10 RPS17 RPS16 RPS15 RPS14 EIF3D RPS19 RPS18 phospho-L13a_associated_wth_the_3prime_UTR_GAIT_element_of_ceruloplasmin_mRNA_within_the_translation_initiation_complex_(complex) RPS15A RPS7 RPS4X RPS5 EMBL_M13699 RPS27A RPS2 EMBL_X03205 Met-tRNAi_eIF2_GTP_(complex) FAU EIF2S1 EIF2S3 EIF2S2 EIF3H EIF3I EIF3J EIF3K EIF3A EIF3B EIF3C EIF1AX EIF3E EIF3F EIF3G RPL13A RPS9 PABPC1 RPS8 RPS26 RPS27 RPS24 RPS25 RPS23 RPS20 RPS21 RPS28 RPS29 eIF2_subunit_complex_(complex) RPS4Y1 EIF4H EIF4E cap-binding_complex_(complex) EIF4B eIF2_GTP_(complex) eIF3_eIGF1A_40S_Met-tRNAi_eIF2_GTP_(complex) 43S__Ceruloplasmin_mRNA_eIF4F_eIF4B_eIF4H_PABP_(complex) RPSA RPS6 EIF4G1 eIF3_subunits_complex_(complex) RPS3A eIF4A_subunits_complex_(complex) RPS3 EIF4A1 40S_ribosomal_complex_(complex) EIF4A2
PID_Grb2_events_in_EGFR_signaling SOS1 EGF_Phospho-EGFR_(Y992__Y1068__Y1086__Y1148__Y1173)_dimer_(complex) p21_RAS EGFR EGF_Phospho-EGFR_(complex) p21_RAS_GTP_(complex) GRB2 GRB2_SOS-EGF-Phospho-EGFR_dimer_(complex) p21_RAS_GDP_(complex) EGF GRB2_SOS1_(complex)
PID_tnfr1pathway LMNB2 MADD CASP2 CASP3 BAG4 TNFRSF1A MAP2K4 BIRC3 Lamin_A/C/Lamin_B1/Lamin_B2_(cleaved)_(complex) CASP8 RIPK1 TNF TNF-alpha/TNF_R1/SODD_(complex) TRADD FADD TRAF2 LMNA CRADD TNF-alpha/TNF_R1/RIP/RAIDD/MADD/TRADD/TRAF2/cIAP_(complex)
REACTOME_REACT_19279 Sema3A_Nrp-1_pPlexinA_Fyn_Fes_Rac-1-GTP_Rnd1_(complex) Plexin-A1-4_FYN_FARP2_(complex) NRP1_Plexin-A1-4_FYN_(complex) Rnd1-GTP_(complex) RRAS RAC1-GTP_(complex) Sema3A_Nrp-1_pPlexinA_Fyn_Fes_Rac-1-GTP_(complex) Sema3A_NRP-1_pPlexin-A_fyn_(complex) Plexin-A1-4_FYN_(complex) FYN NRP1_PlexinA1-4_FARP2_FYN_(complex) FARP2_PIP5KIgamma_(complex) RAC1 R-Ras-GDP_(complex) PIP5K1C FARP2 FES p-Plexin-A1-4_(family) NRP1 SEMA3A PLXNA3 PLXNA2 PLXNA1 PLXNA4 RND1 NRP1_p-Plexin-A1-4_FYN_(complex) Plexin-A1-4_(family) Sema3A_NRP-1_pPlexin-A_Fyn_Fes_(complex) Sema3A_dimer_(complex) Sema3A_Nrp-1_Plexin_A_Fyn_(complex)
PID_Gap_junction_degradation junctional_plaque_prior_to_invagination_(complex) AP2M1 Clathrin_(complex) planar_gap_junction_plaques_containing_Dab2_(complex) gap_junction_plaque_(complex) Invaginating_gap_junction_plaques_(complex) Junctional_channel_(complex)
REACTOME_REACT_6261 Cap_Binding_Complex_(CBC)_(complex) NCBP1 NCBP2 NELFB NELFA CTDP1 RNA_Pol_II_(hypophosphorylated)_complex_bound_to_DSIF_protein_(complex) RNA_Pol_II_(hypophosphorylated)_capped_pre-mRNA_complex_(complex) SUPT5H DSIF_NELF_early_elongation_complex_after_limited_nucleotide_addition_(complex) Early_elongation_complex_with_separated_aborted_transcript_(complex) POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L NELFE POLR2I POLR2H POLR2K POLR2J GTF2F1 NELFCD GTF2F2 RNA_Polymerase_II_holoenzyme_complex_(hypophosphorylated)_TFIIF_complex_(complex) NELF_complex_(complex) SUPT4H1 DSIF_complex_(complex)
BIOCYC_BSUBPOLYAMSYN-PWY SPDSY_(complex) SRM <i>S</i>-adenosylmethionine_decarboxylase_(complex) AMD1
BIOCYC_PWY-6371 OCRL PI4KB PI4KA phosphoinositide-3-kinase__class_III_(complex) IPMK PLCG2 PLCG1 PLCB3 PI4K2B PLCH1 TMEM55B PI4K2A CDIPT phosphatidylinositol_3-kinase_class_IA_p110delta/p85beta_(complex) INPPL1 TMEM55A SACM1L IP6K3 PIK3CB PIK3CD FIG4 PIK3CG ITPKA PIK3R6 ITPKC ITPKB PIK3R3 PIK3R2 PIK3R1 SYNJ2 SYNJ1 MTMR3 PIP5KL1 PIP4K2C PIP4K2B ITPK1 PLCB1 PLCB2 MTMR14 PLCB4 phosphatidylinositol_3-kinase_class_IA_p110alpha/p85alpha_(complex) phosphatidylinositol_3-kinase_class_IA_p110beta/p85gamma_(complex) PIKFYVE hypothetical_protein_MGC26597 phosphatidylinositol_3-kinase__class_IB__p110gamma/p101_(complex) PIK3C2B PIK3C2A PIK3C2G PLCD3 PIK3R5 PIK3C3 IPPK IP6K2 IP6K1 phosphatidylinositol_4-kinase__type_III__alpha INPP5A INPP5B INPP5D phosphatidylinositol_3-kinase__class_IB__p110gamma/p87_(complex) PIP5K1C PIP5K1B INPP5J INPP5K PLCD4 PPIP5K2 PTEN PLCD1 PPIP5K1 PIK3R4 PIK3CA PLCE1 MINPP1 PIP5K1A PLC_BETA_PHOSPHOLIPASE_C_BETA
PID_FGFR1c_ligand_binding_and_activation SDC2 Activated_FGFR_complexed_with_phosphorylated_FRS2__GRB2_and_CBL_(complex) CBL Phospho-FRS2 FGFR1c_homodimer_bound_to_FGF_(complex) GRB2 FGFR1c_homodimer_(complex) Activated_FGFR1c_homodimer_bound_to_FGF_(complex) FGFR1
BIOCYC_PWY-6365 ITPK1 IPMK
PID_RNA_Polymerase_II_Transcription_Initiation ERCC2 ERCC3 TAF13 TAF12 TAF11 TAF10 GTF2A1 GTF2A2 GTF2E1 GTF2E2 RNA_Polymerase_II_(unphosphorylated)_TFIIF_complex_(complex) GTF2B TAF4B RNA_Polymearse_II_NTP_TFIIF_complex_(complex) Pol_II_initiation_complex_(complex) TFIIA_(complex) GTF2H3 GTF2H2 GTF2H1 RNA_Polymerase_II_holoenzyme_complex_(unphosphorylated)_(complex) Pol_II_Initiation_complex_with_phosphodiester-PPi_intermediate_(complex) GTF2H4 POLR2E POLR2D POLR2G POLR2F POLR2A TFIIF_(complex) POLR2C POLR2B POLR2L MNAT1 POLR2I POLR2H POLR2K POLR2J TAF6 TAF5 TAF4 GTF2F1 TAF1 GTF2F2 pol_II_transcription_complex_(complex) TBP TAF9 TFIIH_(complex) TFIID_(complex) TFIIE_(complex) CDK7 CAK_(complex) CCNH
REACTOME_REACT_121036 pro-factor_X_(complex) F2 PROZ pro-protein_C_(complex) F7 F9 PROS1 F10 PROC GAS6
REACTOME_REACT_6866 IN_bound_to_sticky_3prime_ends_of_viral_DNA_(complex) UniProt_P05919_vpu p6_protein_(family) PSIP1 Autointegrated_viral_DNA_as_an_inverted_circle_(complex) UniProt_P04618_rev Autointegrated_viral_DNA_as_smaller_circles_(complex) UniProt_P69726_vpr viral_DNA_with_3prime_sticky_ends_(complex) HMGA1 IN_bound_to_sticky_3prime_ends_of_viral_DNA_in_PIC_(complex) BANF1 UniProt_P69723_vif UniProt_P04585_gag-pol viral_PIC_proteins_(complex) UniProt_P04591_gag Matrix_(family)
REACTOME_REACT_15510 NuMA-bound_microtubules_(complex) NUMA1 NEDD1 NuMA_homodimer_(complex) gamma-TuSC_(complex) TUBG1 TUBG2 centrosome-nucleated_microtubules_(complex) gamma-tubulin_complex_(complex) centrosome-associated_NuMA_(complex) TUBGCP2 TUBGCP3 TUBGCP4 TUBGCP5 TUBGCP6
PID_RNA_Polymerase_II_Pre_transcription_Events NCBP1 NCBP2 NELFB NELFA NELFE CCNT1 CCNT2 TAF4B pol_II_promoter_TFIID_TFIIA_TFIIB_Pol_II_TFIIF_complex_(complex) Elongin_Complex_(complex) Paused_processive_elongation_complex_(complex) TFIIF_(complex) GTF2F1 GTF2F2 SUPT4H1 DSIF_complex_(complex) CCNH Cap_Binding_Complex_(CBC)_(complex) Aborted_elongation_complex_after_arrest_(complex) Processive_elongation_complex_(complex) GTF2E1 GTF2E2 RNA_Polymerase_II_(unphosphorylated)_TFIIF_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_TFIIF_complex_(complex) GTF2B GTF2H3 phospho-Spt5 POLR2E POLR2D POLR2G POLR2F POLR2A POLR2C POLR2B POLR2L POLR2I POLR2H POLR2K POLR2J TAF6 TAF5 TAF4 TAF1 RNA_Polymerase_II_holoenzyme_complex_(hypophosphorylated)_TFIIF_complex_(complex) TAF9 TBP_(complex) CTDP1 TAF13 TAF12 TAF11 TAF10 Elongin_B_C_complex_(complex) pol_II_promoter_TFIID_complex_(complex) TCEB3 TCEB2 FACT_complex_(complex) ERCC2 TFIIA_(complex) ELL RNA_Polymerase_II_holoenzyme_complex_(unphosphorylated)_(complex) TCEA1 RNA_Pol_II_(hypophosphorylated)_capped_pre-mRNA_complex_(complex) MNAT1 TFIIE_(complex) NELFCD NELF_complex_(complex) TFIIH_(complex) CDK7 CDK9 GTF2A1 SSRP1 P-TEFb_complex_(complex) TCEB1 ERCC3 Aborted_early_elongation_complex_(complex) GTF2A2 pol_II_promoter_TFIID_TFIIA_TFIIB_complex_(complex) RNA_Pol_II_(hypophosphorylated)_complex_bound_to_DSIF_protein_(complex) SUPT16H GTF2H2 GTF2H1 GTF2H4 CAK_(complex) Arrested_processive_elongation_complex_(complex) pol_II_closed_pre-initiation_complex_(complex) RNA_Polymerase_II_holoenzyme_complex_(hyperphosphorylated)_(complex)
PID_integrin7_pathway CDH1 ITGAE ITGB7 alphaE/beta7_Integrin/E-cadherin_(complex)
PID_Nicotinate_metabolism NADK QPRT NMNAT3_tetramer_(complex) NMNAT1_hexamer_(complex) NMNAT2_(Mg2+)_(complex) NADSYN1 NMNAT2 NMNAT3 NMNAT1 NAD+_kinase_homotetramer_(Zn2+)_(complex) NADSYN1_homohexamer_(complex)
REACTOME_REACT_13532 PAK2
PID_Inhibition_of_PKR UniProt_P03496_NS NS1_Homodimer_(complex) EIF2AK2 NS1_Homodimer_PKR_Complex_(complex) NS1_Viral_dsRNA_Complex_(complex)
PID_Adenylate_cyclase_activating_pathway G_alpha-olf_GDP_Adenylate_cyclase_(active)_complex_(complex) G_alpha-olf_GDP_complex_(complex) Adenylate_cyclase G_alpha-olf_GTP_Adenylate_cyclase_(active)_complex_(complex) GNAL Adenylate_cyclase_(Mg2+_cofactor)_(complex) G_alpha-olf_GTP_complex_(complex)
REACTOME_11070 RFK FLAD1
PID_Transport_of_connexins_along_the_secretory_pathway GJA1
PID_Golgi_Associated_Vesicle_Biogenesis AP-1_Complex_(complex) ARRB1 CLTA CLTC DNM2 TXNDC5 SH3GL2 BLOC1S6 BLOC1S4 BLOC1S3 BLOC1S1 Cargo_AP-1_Arf1-GTP_beta-Arrestin-1_Vamp_Complex_(complex) ARF1 AP-1_sigma Clathrin_Triskelion_(complex) Cargo_AP-1_beta-Arrestin-1_Vamp_Complex_(complex) NAPA AP1B1 BLOC-1_Complex_(complex) DTNBP1 ARF1/GTP_(complex) AP1G1 Cargo_AP-1_Beta-arrestin_Vamp_Clathrin_Triskelion_Dynamin_Endophilin_Complex_(complex) AP-1_mu
PID_Caspase_8_is_formed_from_procaspase_8 Caspase-8_dimer_(complex) CASP8
BIOCYC_PWY-6502 NUDT1
BIOCYC_PWY-6133 TYR
PID_Processive_synthesis_on_the_C_strand_of_the_telomere PCNA POLD2 Processive_complex_loaded_on_telomere_Okazaki_fragment_Flap_(complex) POLD1 DNA_Polymerase_delta_tetramer_(complex) POLD3 PCNA_homotrimer_(complex) LIG1 Processive_complex_loaded_on_telomere_Okazaki_fragment_complex_(complex) POLD4 Processive_complex_loaded_on_telomere_ligated_C-strand_Okazaki_fragments_(complex)
REACTOME_REACT_508 phospho-IRS_(family) activated_insulin_receptor_(complex) GRB2_phospho-SHC_(complex) INSR CRK INS GRB2_IRS-P_(complex) GRB10_INSR_(complex) Crk_IRS-P_(complex) DOK1 p-IRS1_2_(family) IRS_(family) SHC1 SHC2 SHC3 p-SHC_(family) phospho-insulin_receptor_(complex) SOS1 Crk_SOS_IRS-P_(complex) GRB10 Insulin_(complex) IRS1 IRS2 Crk_SOS_(complex) GRB2
REACTOME_REACT_1846 CCNB2 CCNB1 Cyclin_B1_phospho-Cdc2(Thr_161__Thr_14__Tyr_15)_(complex) CDK1 Cyclin_B_(family) Cyclin_B_phospho-Cdc2(Thr_14)_(complex)
PID_mta3pathway HDAC1 ESR1 Estrogen/ER_alpha_(complex) Estrogen/Estrogen/ER_alpha/ER_alpha/CoA_(complex) MBD3 Estrogen/Estrogen/ER_alpha/ER_alpha_(complex) MTA3/MBD3/HDAC_(complex) MTA3
PID_pdgfrapathway PDGFRA CRKL PI3K_(complex) PDGFA-B-C_(complex) PDGF/PDGFRA_(complex) PLCG1 ELK1 RAPGEF1 CRK CAV3 CAV1 PIK3CA SHC/GRB2/SOS-1_(complex) JUN PDGF/PDGFRA/Caveolin-3_(complex) PKC PDGF/PDGFRA/SHB_(complex) PDGF/PDGFRA/Caveolin-1_(complex) PIK3R1 JAK1 PDGF/PDGFRA/alphav_Integrin_(complex) SRF SHC1 FOS PDGF/PDGFRA/Shf_(complex) SHB PDGF/PDGFRA/Crk_(complex) SHF CSNK2A1 SOS1 PDGF/PDGFRA/CRKL_(complex) ITGAV JUN/FOS_(complex) ELK1/SRF(dimer)_(complex) GRB2 PDGF/PDGFRA/Crk/C3G_(complex)
PID_Vitamin_B5__pantothenate__metabolism FASN SLC5A6 AASDHPPT
PID_Gap_junction_assembly GJA1 Connexin_43_connexon_in_Golgi_transport_vesicle_(complex) Docked_Cx43-containing_transport_vesicles_(complex) gap_junction_plaque_(complex) Connexin_43_hemi-channel_(complex) Junctional_channel_(complex)
PID_FGFR2c_ligand_binding_and_activation GRB2 SDC2 Activated_FGFR_complexed_with_phosphorylated_FRS2__GRB2_and_CBL_(complex) CBL Phospho-FRS2
BIOCYC_PWY0-662 PRPS1L1 PRPS2 PRPS1
REACTOME_REACT_19140 Cam-PDE_1_homodimer_(complex) active_Cam-PDE_1_(complex)
BIOCYC_PWY-6481 TYR
Pathway_9c389b3a1ef31813ed28b8e9a3061b8e.owl SMUG1 TDG MBD4 TDG_glycosylase_uracil_complex_(complex) NTHL1 CCNO
PID_Leukotriene_receptors GPR17 Cysteinyl_leukotriene_receptors GPR17_cysLTs_(complex) Cysteinyl_leukotriene_receptors_Cysteinyl_leukotrienes_(complex) LTB4_receptors_LTB4_(complex) LTB4_receptors
PID_cdmacpathway PLCB1 NFKBIA RELA/p50_(complex) MAP2K2 p50 HRAS I-kappa-B-alpha/RELA/p50/ubiquitin_(complex) p50/RELA/I-kappa-B-alpha_(complex) Cd/Cd_binding_protein_(complex) Cd_binding_protein MAP2K1 MAPK1 PKC RELA RAF1 MAPK3 ubiquitin
REACTOME_REACT_150331 Fibrilins_MFAP2_MFAP5_(complex) TGFB1 Elastic_fibre_with_associated_proteins_(complex) LTBPs_(family) TGF-beta-3_LAP3_(complex) MFAP2__MFAP5_(family) LAP3-binding_integrins_(complex) BMP10 MFAP3 MFAP2 MFAP1 FBLN2 FBLN1 Fibulins_(family) FBLN5 TGF-beta-1_LAP1_(complex) LTBPs_Fibrillin-1_(complex) GDF5 Elastic_fibre_(complex) FBLN1__FBLN2_Fibronectin_matrix_(complex) TGFB3 Fibrillins_BMP2_4_7_10_GF5_(complex) Elastic_fibre-asociated_proteins_(family) LTBP4 LTBP3 LTBP2 LTBP1 EFEMP1 Elastic_fibre_Fibulins_Emilins_(complex) EFEMP2 VTN TGF-beta-3_LAP3_LAP3-binding_integrins_(complex) Elastic_fibre_Fibulins_(complex) TGF-beta-1_LAP1_LAP1-binding_integrins_(complex) BMP7 MFAP5 BMP4 BMP2 LTBP1__LTBP3_(family) LTBP4_TGF-beta-1_LAP1_(complex) TGF_betas_LAPs_(complex) MFAP4 LTBP1__LTBP3_TGF_betas_LAPs_(complex) BMP2_4_7_10_GF5_(family) FBLN1__FBLN2_(family) LAP1_binding-integrins_(complex)
PID_Activation_of_Na_permeable_Kainate_Receptors Edited_GRIK2_homomer_(complex) Edited_GRIK1_homomer_(complex) GRIK1 GRIK2 Edited_GRIK1_and_GRIK2_heteroteramer_(complex) Edited_Kainate_Receptor-glutamate_complex_(complex) Edited_Kainate_receptors_(complex)
REACTOME_REACT_6237 UniProt_P04601_nef
REACTOME_REACT_12447 THEM4 AKT_PIP3_THEM4/TRIB3_(complex) Active_AKT_(family) p-T-AKT_(family) AKT1 AKT2 AKT3 TRIB3 AKT_PIP3_(complex) THEM4/TRIB3_(family) AKT_(family)
REACTOME_REACT_160131 Fibronectin_dimer_(complex) ITGB1 Integrin_alpha5beta1_Fibronectin_matrix_(complex) Integrin_alpha5beta1_(complex) FN1 ITGA5 Integrin_alpha5beta1_FN1_dimer_(complex)
REACTOME_REACT_169168 phosphorylated_anaphase_promoting_complex_(APC/C)_(complex) Ub-EHMT1_(complex) Histone_H3_(family) p-T235_S321-CEBPB_homodimer_(complex) ANAPC11 ANAPC10 H2AFB1 Cyclin_A_phospho-Cdk2(Thr160)_complex_(complex) H2BFS CDKN2C CDKN2A Cdh1_phospho-APC/C_complex_(complex) p-T235_S321-CEBPB_IL8_Gene_Nucleosome_(complex) AP-1(cJun_cFos)_phosphorylated_(complex) HIST3H2BB Histone_H2B_(family) EHMT1_EHMT2_Cdh1_p-APC/C_(complex) Phospho-Ribosomal_protein_S6_kinase_(family) Cdk4/6_INK4A_complex_(complex) FZR1 H2AFX H2AFZ UBA52 UBB UBC phospho-Cdh1_phospho-APC/C_complex_(complex) Ribosomal_protein_S6_kinase_(family) CDK4-6_(family) RPS27A UBE2D1 EHMT1_EHMT2_(complex) p-2S-JUN_p-2S_2T-FOS_IGFBP7_Gene_(complex) UBIQ_HUMAN_(family) CDC16 JUN H3F3B ANAPC2 FOS UBE2E1 Ub-EHMT2_(complex) HIST1H2BD HIST1H2BF IGFBP7 HIST1H2BB HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H2BH ANAPC4 HIST1H2BJ HIST1H2BK RPS6KA1 RPS6KA2 RPS6KA3 CDC27 CDC26 UBE2C CDC23 IL6_Gene_Nucleosome_(complex) Histone_H3_dimethylated_at_lysine-9_(family) HIST1H2BA HIST2H3A ANAPC1 Nucleosome_(Deacetylated)_(complex) Histone_H2A_(family) EHMT1 EHMT2 Cyclin_A_phospho-Cdk(Thr_160)_Cdh1_phosho-APC/C_complex_(complex) ANAPC5 ANAPC7 HIST2H2AA3 IL8_Gene_Nucleosome_(complex) Cyclin_A_(family) IL8_Gene_Nucleosome-H3K9Me2_(complex) IL6 CDK2 INK4A_(family) CDK4 CDK6 IL8 CDKN2B p-T235_S321-CEBPB_IL6_Gene_Nucleosome_(complex) Cyclin_A_phospho-Cdk2(Thr_160)_phospho-Cdh1_phospho-APC/C_complex_(complex) HIST2H2BE HIST1H2AJ HIST1H2AE HIST1H2AD HIST2H4B HIST1H2AC CEBPB CCNA2 CDKN2D CCNA1 IL6_Gene_Nucleosome-H3K9Me2_(complex) Nucleosome_with_Deacetylated_H4_and_H3_Dimethylated_at_Lysine-9_(complex) p-T235_S321-CEBPB_CDKN2B_Gene_(complex) HIST1H3D HIST2H2AC Ub-GLP_Ub-G9a_Cdh1_phospho-APC/C_(complex)
REACTOME_REACT_121248 HSPG2 Heparan-PGs_(family) AGRN HS(3)-PGs_(family) GlcA-Gal-Gal-Xyl-HS_proteins_(family) GPC1 GPC2 GPC3 GPC4 HS(2)-PGs_(family) GPC6 Heparan(2)-PGs_(family) HS(4)-PGs_(family) HS(1)-PGs_(family) HS(5)-PGs_(family) SDC1 SDC2 SDC3 SDC4 Heparan(4)-PGs_(family) Heparan_sulfate/heparin-PGs_(family) Heparan(1)-PGs_(family) Heparan(3)-PGs_(family) GPC5
PID_CDK_mediated_phosphorylation_and_removal_of_Cdc6 PSMD9 PSMD8 PSMB10 PSMD5 PSMD4 PSMD7 PSMD6 PSMD1 PSMD3 PSMD2 PSMD12 CDC6 PSMF1 ubiquitinated_Cdc6_(complex) PSMA2 PSMA3 PSMA1 PSMA6 PSMA7 PSMA4 PSMA5 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSME2 PSME3 PSME1 PSMD14 PSMD11 PSMD10 PSMD13 CDK_(complex) UniProt_P62988_RPS27A_subunit_1_76_subunit_1_76 CDK2 PSMB9 PSMB8 PSMB7 PSMB6 PSMB5 PSMB3 PSMB2 PSMB1
REACTOME_REACT_21247 p21_RAS_GTP_(complex) Activated_FGFR_p-FRS2_p-SHP2_(complex) p21_RAS_(family) Activated_FGFR_complexed_with_FRS2-alpha_(complex) SOS1 NRAS Activated_FGFR_p-FRS2_GRB2_SOS1_(complex) Activated_FGFR_complexed_with_FRS2-beta_(complex) FRS3 FRS2 Activated_FGFR_complexed_with_phosphorylated_FRS2-beta_(complex) Activated_FGFR_p-FRS2_SHP2_(complex) GRB2 PTPN11 Activated_FGFR_p-FRS2_(complex) Activated_FGFR_p-FRS2alpha_(complex) KRAS HRAS GRB2_SOS1_(complex)