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Update README.md
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rmcolq authored Aug 23, 2024
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Expand Up @@ -3,6 +3,8 @@ Workflow to run [squirrel](https://github.com/aineniamh/squirrel) through a GUI

**S**ome **QUI**ck **R**earranging to **R**esolve **E**volutionary **L**inks

A full walkthrough of this workflow can be found [here](https://artic.network/mpxv/mpxv-phylogenetics-epi2me-sop.html)

Squirrel allows the following analyses of MPXV Clade I or Clade II sequences:
1. Generate an alignment
2. Run basic sequence QC on the alignment looking for standard errors arising from consensus building pipelines or low sequencing depth
Expand All @@ -24,4 +26,4 @@ If you check the `run_phylo` option, it will construct a tree using IQtree. You
If you check both the `run_phylo` and `seq_qc` options, and additional step is performed to generate a more informed mask file.

## More information
More information on the input parameters and methods can be found on [the main page for squirrel](https://github.com/aineniamh/squirrel).
More information on the input parameters and methods can be found on [the main page for squirrel](https://github.com/aineniamh/squirrel).

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