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Meta-analysis of TCGA copy number data

In this repository are the scripts used for the analysis performed in the manuscript: Somatic Copy Number Alterations in Human Cancers: An Analysis of Publically Available Data From the Cancer Genome Atlas

L. Harbers et al, Frontiers in Oncology (2021)

Obtaining TCGA copy number data

TCGA copy number data can be obtained by running the getTCGA_data.R script. Set the cache (where you want to save the data) and specify where you want to save the clinical data and it will automatically download all the available copy number data and associated clinical information.

Running the analysis and plotting

To then run the analysis and generate the plots that are shown in the manuscript you will have to run TCGA-cna-plots.R. All the required data files are available in the data/ directory of this repository. Except the TCGA copy number data, which is too large to include. But this can be downloaded with the above mentioned script.

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Scripts used for the analysis of TCGA data

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