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fixup: genotype datasets using reconstructed roots
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j23414 committed Jun 4, 2024
1 parent 6cff5f4 commit 1e6b119
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Showing 17 changed files with 94 additions and 785 deletions.
4 changes: 2 additions & 2 deletions nextclade/datasets/all/pathogen.json
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Expand Up @@ -34,7 +34,7 @@
},
"qc": {
"frameShifts": {
"enabled": false
"enabled": true
},
"missingData": {
"enabled": false,
Expand All @@ -60,7 +60,7 @@
"windowSize": 100
},
"stopCodons": {
"enabled": false
"enabled": true
}
},
"schemaVersion": "3.0.0",
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26 changes: 13 additions & 13 deletions nextclade/datasets/denv1/genome_annotation.gff3
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@@ -1,14 +1,14 @@
##gff-version 3
##sequence-region NC_001477.1 1 10735
NC_001477.1 feature gene 95 436 . + . codon_start=1;gene=C;gene_name=C;
NC_001477.1 feature gene 437 709 . + . codon_start=1;gene=pr;gene_name=pr;
NC_001477.1 feature gene 437 934 . + . codon_start=1;gene=M;gene_name=M;
NC_001477.1 feature gene 935 2419 . + . codon_start=1;gene=E;gene_name=E;
NC_001477.1 feature gene 2420 3475 . + . codon_start=1;gene=NS1;gene_name=NS1;
NC_001477.1 feature gene 3476 4129 . + . codon_start=1;gene=NS2A;gene_name=NS2A;
NC_001477.1 feature gene 4130 4519 . + . codon_start=1;gene=NS2B;gene_name=NS2B;
NC_001477.1 feature gene 4520 6376 . + . codon_start=1;gene=NS3;gene_name=NS3;
NC_001477.1 feature gene 6377 6757 . + . codon_start=1;gene=NS4A;gene_name=NS4A;
NC_001477.1 feature gene 6758 6826 . + . codon_start=1;gene=2K;gene_name=2K;
NC_001477.1 feature gene 6827 7573 . + . codon_start=1;gene=NS4B;gene_name=NS4B;
NC_001477.1 feature gene 7574 10270 . + . codon_start=1;gene=NS5;gene_name=NS5;
##sequence-region Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome 1 10735
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 95 436 . + . codon_start=1;gene=C;gene_name=C;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 437 709 . + . codon_start=1;gene=pr;gene_name=pr;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 437 934 . + . codon_start=1;gene=M;gene_name=M;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 935 2419 . + . codon_start=1;gene=E;gene_name=E;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 2420 3475 . + . codon_start=1;gene=NS1;gene_name=NS1;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 3476 4129 . + . codon_start=1;gene=NS2A;gene_name=NS2A;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 4130 4519 . + . codon_start=1;gene=NS2B;gene_name=NS2B;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 4520 6376 . + . codon_start=1;gene=NS3;gene_name=NS3;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 6377 6757 . + . codon_start=1;gene=NS4A;gene_name=NS4A;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 6758 6826 . + . codon_start=1;gene=2K;gene_name=2K;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 6827 7573 . + . codon_start=1;gene=NS4B;gene_name=NS4B;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv1/genome feature gene 7574 10270 . + . codon_start=1;gene=NS5;gene_name=NS5;
9 changes: 7 additions & 2 deletions nextclade/datasets/denv1/pathogen.json
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@@ -1,5 +1,9 @@
{
"alignmentParams": {
"penaltyGapOpen": 8,
"penaltyGapOpenInFrame": 12,
"penaltyGapOpenOutOfFrame": 14,
"gapAlignmentSide": "left",
"minSeedCover": 0.1,
"minLength": 1000
},
Expand All @@ -17,6 +21,7 @@
"experimental": true,
"files": {
"changelog": "CHANGELOG.md",
"examples": "sequences.fasta",
"genomeAnnotation": "genome_annotation.gff3",
"pathogenJson": "pathogen.json",
"readme": "README.md",
Expand All @@ -29,7 +34,7 @@
},
"qc": {
"frameShifts": {
"enabled": false
"enabled": true
},
"missingData": {
"enabled": false,
Expand All @@ -55,7 +60,7 @@
"windowSize": 100
},
"stopCodons": {
"enabled": false
"enabled": true
}
},
"schemaVersion": "3.0.0",
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182 changes: 2 additions & 180 deletions nextclade/datasets/denv1/reference.fasta

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2 changes: 1 addition & 1 deletion nextclade/datasets/denv1/tree.json

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26 changes: 13 additions & 13 deletions nextclade/datasets/denv2/genome_annotation.gff3
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@@ -1,14 +1,14 @@
##gff-version 3
##sequence-region NC_001474.2 1 10723
NC_001474.2 feature gene 97 438 . + . codon_start=1;gene=C;gene_name=C;
NC_001474.2 feature gene 439 711 . + . codon_start=1;gene=pr;gene_name=pr;
NC_001474.2 feature gene 439 936 . + . codon_start=1;gene=M;gene_name=M;
NC_001474.2 feature gene 937 2421 . + . codon_start=1;gene=E;gene_name=E;
NC_001474.2 feature gene 2422 3477 . + . codon_start=1;gene=NS1;gene_name=NS1;
NC_001474.2 feature gene 3478 4131 . + . codon_start=1;gene=NS2A;gene_name=NS2A;
NC_001474.2 feature gene 4132 4521 . + . codon_start=1;gene=NS2B;gene_name=NS2B;
NC_001474.2 feature gene 4522 6375 . + . codon_start=1;gene=NS3;gene_name=NS3;
NC_001474.2 feature gene 6376 6756 . + . codon_start=1;gene=NS4A;gene_name=NS4A;
NC_001474.2 feature gene 6757 6825 . + . codon_start=1;gene=2K;gene_name=2K;
NC_001474.2 feature gene 6826 7569 . + . codon_start=1;gene=NS4B;gene_name=NS4B;
NC_001474.2 feature gene 7570 10269 . + . codon_start=1;gene=NS5;gene_name=NS5;
##sequence-region Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome 1 10723
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 97 438 . + . codon_start=1;gene=C;gene_name=C;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 439 711 . + . codon_start=1;gene=pr;gene_name=pr;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 439 936 . + . codon_start=1;gene=M;gene_name=M;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 937 2421 . + . codon_start=1;gene=E;gene_name=E;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 2422 3477 . + . codon_start=1;gene=NS1;gene_name=NS1;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 3478 4131 . + . codon_start=1;gene=NS2A;gene_name=NS2A;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 4132 4521 . + . codon_start=1;gene=NS2B;gene_name=NS2B;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 4522 6375 . + . codon_start=1;gene=NS3;gene_name=NS3;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 6376 6756 . + . codon_start=1;gene=NS4A;gene_name=NS4A;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 6757 6825 . + . codon_start=1;gene=2K;gene_name=2K;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 6826 7569 . + . codon_start=1;gene=NS4B;gene_name=NS4B;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv2/genome feature gene 7570 10269 . + . codon_start=1;gene=NS5;gene_name=NS5;
9 changes: 7 additions & 2 deletions nextclade/datasets/denv2/pathogen.json
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@@ -1,5 +1,9 @@
{
"alignmentParams": {
"penaltyGapOpen": 8,
"penaltyGapOpenInFrame": 12,
"penaltyGapOpenOutOfFrame": 14,
"gapAlignmentSide": "left",
"minSeedCover": 0.1,
"minLength": 1000
},
Expand All @@ -17,6 +21,7 @@
"experimental": true,
"files": {
"changelog": "CHANGELOG.md",
"examples": "sequences.fasta",
"genomeAnnotation": "genome_annotation.gff3",
"pathogenJson": "pathogen.json",
"readme": "README.md",
Expand All @@ -29,7 +34,7 @@
},
"qc": {
"frameShifts": {
"enabled": false
"enabled": true
},
"missingData": {
"enabled": false,
Expand All @@ -55,7 +60,7 @@
"windowSize": 100
},
"stopCodons": {
"enabled": false
"enabled": true
}
},
"schemaVersion": "3.0.0",
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182 changes: 2 additions & 180 deletions nextclade/datasets/denv2/reference.fasta

Large diffs are not rendered by default.

2 changes: 1 addition & 1 deletion nextclade/datasets/denv2/tree.json

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26 changes: 13 additions & 13 deletions nextclade/datasets/denv3/genome_annotation.gff3
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@@ -1,14 +1,14 @@
##gff-version 3
##sequence-region NC_001475.2 1 10707
NC_001475.2 feature gene 95 436 . + . codon_start=1;gene=C;gene_name=C;
NC_001475.2 feature gene 437 709 . + . codon_start=1;gene=pr;gene_name=pr;
NC_001475.2 feature gene 437 934 . + . codon_start=1;gene=M;gene_name=M;
NC_001475.2 feature gene 935 2419 . + . codon_start=1;gene=E;gene_name=E;
NC_001475.2 feature gene 2414 3469 . + . codon_start=1;gene=NS1;gene_name=NS1;
NC_001475.2 feature gene 3470 4123 . + . codon_start=1;gene=NS2A;gene_name=NS2A;
NC_001475.2 feature gene 4124 4513 . + . codon_start=1;gene=NS2B;gene_name=NS2B;
NC_001475.2 feature gene 4514 6370 . + . codon_start=1;gene=NS3;gene_name=NS3;
NC_001475.2 feature gene 6371 6751 . + . codon_start=1;gene=NS4A;gene_name=NS4A;
NC_001475.2 feature gene 6752 6820 . + . codon_start=1;gene=2K;gene_name=2K;
NC_001475.2 feature gene 6821 7564 . + . codon_start=1;gene=NS4B;gene_name=NS4B;
NC_001475.2 feature gene 7565 10264 . + . codon_start=1;gene=NS5;gene_name=NS5;
##sequence-region Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome 1 10707
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 95 436 . + . codon_start=1;gene=C;gene_name=C;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 437 709 . + . codon_start=1;gene=pr;gene_name=pr;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 437 934 . + . codon_start=1;gene=M;gene_name=M;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 935 2419 . + . codon_start=1;gene=E;gene_name=E;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 2414 3469 . + . codon_start=1;gene=NS1;gene_name=NS1;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 3470 4123 . + . codon_start=1;gene=NS2A;gene_name=NS2A;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 4124 4513 . + . codon_start=1;gene=NS2B;gene_name=NS2B;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 4514 6370 . + . codon_start=1;gene=NS3;gene_name=NS3;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 6371 6751 . + . codon_start=1;gene=NS4A;gene_name=NS4A;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 6752 6820 . + . codon_start=1;gene=2K;gene_name=2K;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 6821 7564 . + . codon_start=1;gene=NS4B;gene_name=NS4B;
Reconstructed_root_sequence_of_https_nextstrain_org_dengue/denv3/genome feature gene 7565 10264 . + . codon_start=1;gene=NS5;gene_name=NS5;
9 changes: 7 additions & 2 deletions nextclade/datasets/denv3/pathogen.json
Original file line number Diff line number Diff line change
@@ -1,5 +1,9 @@
{
"alignmentParams": {
"penaltyGapOpen": 8,
"penaltyGapOpenInFrame": 12,
"penaltyGapOpenOutOfFrame": 14,
"gapAlignmentSide": "left",
"minSeedCover": 0.1,
"minLength": 1000
},
Expand All @@ -17,6 +21,7 @@
"experimental": true,
"files": {
"changelog": "CHANGELOG.md",
"examples": "sequences.fasta",
"genomeAnnotation": "genome_annotation.gff3",
"pathogenJson": "pathogen.json",
"readme": "README.md",
Expand All @@ -29,7 +34,7 @@
},
"qc": {
"frameShifts": {
"enabled": false
"enabled": true
},
"missingData": {
"enabled": false,
Expand All @@ -55,7 +60,7 @@
"windowSize": 100
},
"stopCodons": {
"enabled": false
"enabled": true
}
},
"schemaVersion": "3.0.0",
Expand Down
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