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Add Welsh et al. epitope sites and escape scores #135

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merged 3 commits into from
Jan 27, 2024

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@huddlej huddlej commented Dec 15, 2023

Description of proposed changes

Adds distance maps for epitope sites and average escape scores based on antigenic escape scores from Welsh et al. 2023 [1], adds these maps to the distance maps config, and only exposes these distances through the nextflu-private builds Auspice config JSON for now. Adds the Python notebook used to generate these distance maps from the original raw data, so we can rebuild them later as needed.

[1] https://www.biorxiv.org/content/10.1101/2023.12.12.571235v1

Checklist

  • Add logic to workflow to only use these distance maps in nextflu-private builds
  • Checks pass

Adds distance maps for epitope sites and average escape scores based on
antigenic escape scores from Welsh et al. 2023 [1], adds these maps
to the distance maps config, and only exposes these distances through
the nextflu-private builds Auspice config JSON for now. Adds the Python
notebook used to generate these distance maps from the original raw
data, so we can rebuild them later as needed.

[1] https://www.biorxiv.org/content/10.1101/2023.12.12.571235v1
@huddlej huddlej force-pushed the add-welsh-epitope-maps branch from c678fa0 to 9c619a2 Compare January 18, 2024 00:40
@huddlej huddlej marked this pull request as ready for review January 18, 2024 00:41
@huddlej huddlej merged commit 61aed50 into master Jan 27, 2024
7 checks passed
@huddlej huddlej deleted the add-welsh-epitope-maps branch January 27, 2024 04:03
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