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Compare Tool
To enable users to simply explore the differences between two subsets of our data on our servers, we have created an "Compare" tool ✨
This tool consists of two filter panels with many options for users to click through and choose which differences they want to see. The results are shown in an overview table (counts) as well as three separate tables for the subsets unique to each search category and the subset in common between the two chosen sets. All tables are easily downloadable.
To showcase how to use the compare tool on an example, we are showing the steps on how to filter and use the compare tool for the example written in our paper manuscript (https://doi.org/10.1101/2023.02.03.526935).
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A. Choose if you want to include only "complete genomes" in the next steps or both "complete and partial genomes" (term definitions: https://www.ncbi.nlm.nih.gov/assembly/help/). In our example, we chose both complete and partial genomes.
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B. Choose if you want to compare on genomic or protein level. In our example, we chose "nucleotide" level comparison.
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C. Choose based on which reference genome you want to explore variants. In our example, we chose the reference genome: "ON563414.3".
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D. and E. are the two filter settings users can choose to compare different things from.
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F. Choose which genes you want included. Here all are selected per default.
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G. Choose which sequencing technologies to compare. In our example, we chose all Illumina sequencing technologies on one side and all Oxford Nanopore sequencing technologies on the other side, excluding mixed methods and other undefined methods.
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H. Choose countries to compare. We selected all in our example.
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I. Choose Date intervals to compare samples from. We left the default setting.
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J. Press the "compare" button to submit the queries.
The loading screen indicates that the query is currently processing and loading.
Note: User can click export button to download the result.
The amino acid mutations unique to the each selection as well as the mutations in common are listed here. Users can further filter these here as well.
An overview table of counts unique to the each selection as well as the mutations in common is shown here to provide the user with a quick overview of the results without the need to download the three tables.
The three data subsets are shown at the bottom and are available for download.
MpoxRadar Tools🧰: https://mpoxradar.net/Tool
Help page describing each tool functionality: https://mpoxradar.net/Help