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v2.3.1

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@kapsakcj kapsakcj released this 10 Mar 16:42
· 8 commits to main since this release
715123f

PHVG v2.3.1 release notes

This patch release adds capability for detection of mutations known to be associated with Tamiflu resistance, includes bug fixes for Influenza Type B subtyping, and updates default input parameters (pangolin docker image, nextclade_dataset_tag, nextclade docker image).

New Features

  • New column tamiflu_resistance_aa_subs containing nextclade-detected substitutions that have been described in the literature to confer resistance to tamiflu (Influenza-specific)
  • New optional boolean input parameters for Mercury_Prep_N_Batch:
    • using_clearlabs_data, using_reads_dehosted, usa_territory
  • New optional input parameter for Freyja_Plot workflow: mincov

Default Docker Images and Input Parameter Updates

  • Default pangolin docker image: staphb/pangolin:4.2-pdata-1.18.1.1
  • Default nextclade docker image: nextstrain/nextclade:2.11.0
  • Default nextclade_dataset_tag for SARS-CoV-2: 2023-02-25T12:00:00Z
  • Default freyja docker image: staphb/freyja:1.3.11

Other Changes

  • Bug fix: Type B Influenza subtypes no longer duplicated from ABRicate output
  • Updates to GitHub Actions workflows for automated testing

Documentation can be found here: https://theiagen.notion.site/Theiagen-Public-Health-Resources-a4bd134b0c5c4fe39870e21029a30566

What's Changed

  • Expose minimum coverage option in Freyja_Plot by @sage-wright in #211
  • Enable alternative read and assembly files by @sage-wright in #210
  • Fix Bug RE Type-B subtyping (TheiaCoV_Illumina PE flu track) by @kevinlibuit in #216
  • update nextclade TSV parsing for SC2: clade_legacy. Also update Flu & nextclade by @kapsakcj and @cimendes in #213
  • update default pangolin docker to staphb/pangolin:4.2-pdata-1.18.1.1 and nextclade_dataset_tag for SC2 by @kapsakcj in #217

Full Changelog: v2.3.0...v2.3.1

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