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Commit from GitHub Actions (Update Indications on Merge)
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TanskaAnnna committed May 21, 2021
1 parent c8993c2 commit 1299361
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Showing 3 changed files with 105 additions and 38 deletions.
64 changes: 64 additions & 0 deletions indication_paths.json
Original file line number Diff line number Diff line change
Expand Up @@ -195516,5 +195516,69 @@
"reference": [
"https://go.drugbank.com/drugs/DB09245"
]
},
{
"directed": true,
"graph": {
"_id": "DB00792_MESH_D065631_3",
"disease": "Allergic rhinitis",
"disease_mesh": "MESH:D065631",
"drug": "loratadine",
"drug_mesh": "MESH:D017336",
"drugbank": "DB:DB00792"
},
"links": [
{
"key": "decreases activity of",
"source": "MESH:D017336",
"target": "UniProt:P35367"
},
{
"key": "positively regulates",
"source": "UniProt:P35367",
"target": "GO:0004969"
},
{
"key": "positively correlated with",
"source": "GO:0004969",
"target": "GO:0002441"
},
{
"key": "positively correlated with",
"source": "GO:0002441",
"target": "MESH:D065631"
}
],
"multigraph": true,
"nodes": [
{
"id": "MESH:D017336",
"label": "Drug",
"name": "loratadine"
},
{
"id": "UniProt:P35367",
"label": "Protein",
"name": "Histamine H1 receptor"
},
{
"id": "GO:0004969",
"label": "MolecularActivity",
"name": "histamine receptor activity"
},
{
"id": "GO:0002441",
"label": "BiologicalProcess",
"name": "histamine secretion involved in inflammatory response"
},
{
"id": "MESH:D065631",
"label": "Disease",
"name": "Allergic rhinitis"
}
],
"reference": [
"https://go.drugbank.com/drugs/DB00455"
]
}
]
40 changes: 40 additions & 0 deletions indication_paths.yaml
Original file line number Diff line number Diff line change
Expand Up @@ -122909,3 +122909,43 @@
name: Depressive disorder
reference:
- https://go.drugbank.com/drugs/DB09245
- directed: true
graph:
_id: DB00792_MESH_D065631_3
disease: Allergic rhinitis
disease_mesh: MESH:D065631
drug: loratadine
drug_mesh: MESH:D017336
drugbank: DB:DB00792
links:
- key: decreases activity of
source: MESH:D017336
target: UniProt:P35367
- key: positively regulates
source: UniProt:P35367
target: GO:0004969
- key: positively correlated with
source: GO:0004969
target: GO:0002441
- key: positively correlated with
source: GO:0002441
target: MESH:D065631
multigraph: true
nodes:
- id: MESH:D017336
label: Drug
name: loratadine
- id: UniProt:P35367
label: Protein
name: Histamine H1 receptor
- id: GO:0004969
label: MolecularActivity
name: histamine receptor activity
- id: GO:0002441
label: BiologicalProcess
name: histamine secretion involved in inflammatory response
- id: MESH:D065631
label: Disease
name: Allergic rhinitis
reference:
- https://go.drugbank.com/drugs/DB00455
39 changes: 1 addition & 38 deletions submission.yaml
Original file line number Diff line number Diff line change
@@ -1,38 +1 @@
- directed: true
graph:
disease: Allergic rhinitis
disease_mesh: MESH:D065631
drug: loratadine
drug_mesh: MESH:D017336
drugbank: DB:DB00792
links:
- key: decreases activity of
source: MESH:D017336
target: UniProt:P35367
- key: positively regulates
source: UniProt:P35367
target: GO:0004969
- key: positively correlated with
source: GO:0004969
target: GO:0002441
- key: positively correlated with
source: GO:0002441
target: MESH:D065631
multigraph: true
nodes:
- id: MESH:D017336
label: Drug
name: loratadine
- id: UniProt:P35367
label: Protein
name: Histamine H1 receptor
- id: GO:0004969
label: MolecularActivity
name: histamine receptor activity
- id: GO:0002441
label: BiologicalProcess
name: histamine secretion involved in inflammatory response
- id: MESH:D065631
label: Disease
name: Allergic rhinitis
reference: https://go.drugbank.com/drugs/DB00455

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