In our work for MOSAIC (paper), we have developed improved starting points for ECHO models. As such, we have integrated these starting points for the ECHO model for the newest version, v4.0. Other bug fixes have also been added, detailed in the commit notes. Methods for these improved starting points appear in ECHO_V4_Update.pdf, as well as comparisons with datasets used in the Bioinformatics publication. Due to these improvements, we highly recommend that new users use ECHO v4.0+. However, the journal version will still be available for those who prefer it.