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tfsites modules for defineBindingStites starting with Position Frequency Matrix from JASPAR

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genepattern/tfsites.GenerateMotifDatabase

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tfsites.defineTFBindingSitesFromPFM

Normalizes the median fluorescence intensity (MFI) values in a Position Frequency Matrix from JASPAR data file for a transcription factor of interest. The k-mer with the maximum MFI that conforms to the IUPAC definition of a binding site is normalized to 1.0 and all other k-mers are normalized relative to that MFI value. For example, a normalized value of 0.1 is 10% of the maximum MFI.

Created in collaboration with the Emma Farley lab (UCSD).

See documentation at https://genepattern.github.io/tfsites.DefineTfBindingSitesFromPFM/v1/

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tfsites modules for defineBindingStites starting with Position Frequency Matrix from JASPAR

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