Cistrome data

From NuclearReceptorCistrome:

Nuclear receptors are a class of transcription factors that can bind DNA directly in response to ligand induction. In concert with other proteins, nuclear receptors are involved in important physiological and pathological functions. Recently, the application of ChIP_chip/seq teachniques renders the accurate and effective dectection of nuclear receptor binding sites possible. We desinged a web-interface that enables the users to access and download the processed ChIP_chip/seq data of nuclear receptors, co-regulators and histone modifications. The web resources also includes processed differential expression data under ligand induction in conditions matched to ChIP_chip/seq data whenever possible. All the ChIP_chip/seq peak regions are annotated with enriched HRE and co-regulator motifs. A list of predicted hormone response genes from integration of nuclear receptor ChIP_chip/seq data and differential expression data is also readily available to the users.

The Cistrome data are organized into three categories:

1. Cistrome - cell type and treatment-specific transcription factor binding sites;

2. Epigenome - cell type and treatment-specific epigenetic marks;

3. Motif - predicted transcription factor binding sites.

The data are named according to the original Cistrome convention.